Irreversible pulpitis

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Information
Disease name
Irreversible pulpitis
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT05733468 Active, not recruiting Phase 4 TheraCal LC Coronal Pulpotomy and MTA Coronal Pulpotomy in Mature Permanent Molars July 1, 2022 May 30, 2024
NCT06240130 Active, not recruiting N/A Outcome Following Use of NaOCl and Chlorhexidine as Wound Lavage Agents November 1, 2022 May 1, 2024
NCT01561183 Completed N/A Vital Pulp Therapy (VPT) Using Calcium Enriched Mixture (CEM) to Treat Irreversible Pulpitis March 2012 December 2016
NCT01572116 Completed Phase 2 Effect of Sufentanil on the Rate of Anesthesia January 2010 October 2011
NCT01912755 Completed Phase 4 Anesthetic Efficacy of Articaine and Lidocaine in Lower Molars With Irreversible Pulpits February 2010 January 2011
NCT02086097 Completed Phase 4 Dexketoprofen Trometamol in Postoperative Endodontic Pain August 2013 April 2014
NCT02417337 Completed Phase 2 Efficacy of Different Drugs to Control Post Root Canal Treatment Pain August 2012 January 2015
NCT02601911 Completed Phase 2 Effect of Premedication on Success of Inferior Alveolar Nerve Block Injection September 2015 June 2016
NCT02614118 Completed Phase 2 Premedication Efficacy of Oral Ketorolac and Ketorolac/ Acetaminophen on Post Treatment Pain September 2015 May 2016
NCT02807298 Completed Phase 3 4% Articaine and 2% Lidocaine by Intraligamentary Technique in Irreversible Pulpitis June 2014 December 2014
NCT02923687 Completed Phase 2 Premedication Efficacy of Ketorolac Infiltration on Post Endodontic Pain September 2016 June 2017
NCT02981693 Completed N/A Evaluation of iRoot SP as Root Canal Sealer: A Clinical Study January 2014 November 2016
NCT03146481 Completed Phase 2/Phase 3 Pre-operative Aceclofenac on the Anesthetic Efficacy of IANB in Symptomatic Irreversible Pulpitis July 2016 July 2017
NCT01496846 Completed Phase 4 Efficacy Study of Articaine Versus Lidocaine as Supplemental Infiltration in Inflamed Molars September 2011 February 2016
NCT03749408 Completed Phase 2/Phase 3 Effect of Addition of Mannitol to Bupivacaine on IANB Success and Post-endodontic Pain December 2012 June 2014
NCT04654845 Completed N/A Patient Perception Between Two Emergency Treatments of Symptomatic Irreversible Pulpitis. November 16, 2020 July 30, 2022
NCT04784949 Completed N/A PRF Pulpotomy Using Different Bioceramic Materials in Permanent Molars August 1, 2019 January 1, 2021
NCT04870398 Completed N/A Partial Pulpotomy in Mature Permanent Teeth With Signs and Symptoms of Irreversible Pulpits January 5, 2017 April 23, 2021
NCT04900571 Completed Phase 4 Comparison of Nitrofurantoin and Calcium Hydroxide as Intracanal Medicaments in Alleviating Post-operative Pain January 1, 2021 May 18, 2021
NCT04964622 Completed Phase 1/Phase 2 the Effect of Preoperative Sodium Ibuprofen on Postoperative Endodontic Pain December 1, 2021 September 1, 2022
NCT05038059 Completed N/A Ethanolic Extract of Sapindus Mukorrossi as Final Endodontic Irrigant. April 2, 2020 September 1, 2021
NCT05306431 Completed Phase 2 Comparison of Antimicrobial Action of Sodium Hypochlorite and Polyhexamethylene Biguanide as Root Canal Irrigants June 1, 2022 November 30, 2022
NCT05568563 Completed N/A Comparison of Effectiveness of Pre-cooling With Ethyl Chloride Versus Honey August 1, 2022 September 30, 2022
NCT05778227 Completed N/A Comparing Different Single and Combination Chelating Agents on Sealer Penetration and Dentin Erosion. November 16, 2021 August 20, 2023
NCT06081335 Completed N/A Can Instrumentation Kinematics Affect Post Operative Pain and Substance P Levels? A Randomized Controlled Trial March 15, 2023 June 5, 2023
NCT06176378 Completed N/A A Clinical and Radiographic Evaluation of Low-Level Diode Laser Full Pulpotomy in Vital Permanent Teeth October 12, 2020 March 14, 2023
NCT06206304 Completed Relationship of Eye Colour With Anesthetic Success and Post-Operative Pain June 18, 2023 December 11, 2023
NCT06437197 Completed N/A Evaluation of Using Platelet-Rich Fibrin in Adult Pulpotomy March 12, 2023 March 23, 2024
NCT06427070 Not yet recruiting N/A Effectiveness of Two Intracanal Irrigation Solutions May 23, 2024 June 1, 2024
NCT06420583 Not yet recruiting N/A Post Operative Pain and Oral Health Related Quality of Life Following Pulpotomy VS Extraction of Permanent First Molar November 2024 December 2025
NCT04922229 Not yet recruiting N/A Comparative Effectiveness in the Management of Irreversible Pulpitis December 1, 2024 December 31, 2031
NCT06237985 Not yet recruiting N/A Effect of Conservative Root Canal Instrumentation on the Release of Inflammatory Mediators in Root Canal Treatments February 15, 2024 April 30, 2024
NCT04807244 Not yet recruiting N/A Treatment of Deep Carious Lesions With Selective Caries Removal, Partial or Full Pulpotomy April 1, 2021 September 30, 2025
NCT06183203 Not yet recruiting N/A Treatment Outcomes of Pulpotomy vs. Pulpectomy in Vital Primary Molars With Symptomatic Irreversible Pulpitis February 15, 2024 June 30, 2027
NCT06194773 Recruiting N/A The Effect of Totalfil and Neosealer Sealers on the Post-endodontic Pain June 26, 2023 January 6, 2025
NCT06231290 Recruiting N/A The Influence of Magnification and Clinical Experience on the Outcome of Pulpotomy in Mature Adult Teeth March 20, 2024 July 2025
NCT06245161 Recruiting N/A Efficacy of Computer Controlled Intraosseous Anesthesia in Pediatric Dental Patients October 1, 2023 May 2024
NCT05622266 Recruiting N/A Effectiveness of Pulpotomy in the Management of Mature Permanent Tooth With Irreversible Pulpits January 1, 2022 December 30, 2024
NCT05761730 Recruiting Phase 1 Oral Dexamethasone for the Management of Symptomatic Irreversible Pulpitis Without Performing Pulpotomy February 15, 2023 June 2023
NCT06358833 Recruiting N/A Comparison of Endodontic Postoperative Pain Using Different Irrigation Systems April 15, 2024 December 31, 2024
NCT05811403 Recruiting N/A Epigallocatechin Gallate (EGCG) as a Flushing Agent During Full Pulpotomy in Mature Permanent Molars With Irreversible Pulpitis July 1, 2023 December 1, 2025
NCT06142799 Recruiting N/A Influence of Moment of Restoration in Pain After a Root Canal Treatment November 14, 2023 April 30, 2024
NCT06149845 Recruiting N/A Pulpotomy in Vital Primary Molars Diagnosed With Symptomatic Irreversible Pulpitis March 21, 2024 September 2026
NCT06194721 Recruiting N/A The Effect of Intra-pulpal Anesthesia With Cryotherapy on Intra-operative Pain June 6, 2023 January 6, 2025
NCT06433245 Recruiting N/A Outcome Following Use of Different Concentrations of NaOCl as Wound Lavage and Hemostatic Agent in Partial Pulpotomy May 23, 2024 December 23, 2025
NCT04157036 Terminated Phase 3 Evaluation of Methylprednisolone or Ibuprofen on Efficacy of Nerve Blocks With Symptomatic Irreversible Pulpitis February 1, 2020 October 6, 2021
NCT05277246 Unknown status N/A Effect of Using Different Concentrations of NaOCI on IL-8 Level March 20, 2022 July 20, 2022
NCT05190406 Unknown status N/A Success and Quality of Life Following Complete Pulpotomy and Root Canal Treatment June 1, 2021 August 1, 2022
NCT01167985 Unknown status Phase 2 A Clinical Study: the Antibacterial Effect of Insoluble Antibacterial Nanoparticles (IABN) Incorporated in Dental Materials for Root Canal Treatment July 2013 December 2015
NCT03163420 Unknown status Phase 2/Phase 3 Diclofenac Potassium on IANB Efficacy in Symptomatic Irreversible Pulpitis July 2016 July 2017
NCT03186690 Unknown status N/A Similar Outcomes of Vital Pulp Therapy Using Mineral Trioxide Aggregate or Biodentine™ July 4, 2013 October 4, 2023
NCT03415724 Unknown status N/A Comparison of Anesthetic Efficacy of Dexmedetomidine and Epinephrine With Lidocaine in Irreversible Pulpitis February 1, 2018 April 30, 2018
NCT05279820 Unknown status N/A Comparative Study of the Outcome of Partial and Full Pulpotomy in Irreversible Pulpits June 1, 2021 January 2024
NCT05349929 Unknown status Phase 2 Analgesic Effect of Anahil and Ibuprofen on Pain After Root Canal Therapy in Patients With Pulpitis of the Molars in Qazvin(a City in Iran) May 2022 December 2022
NCT05427851 Unknown status N/A Diode Laser Pulpotomy of Mature Permanent Molars With Irreversible Pulpitis April 10, 2019 September 1, 2022
NCT05441995 Unknown status N/A Cryotherapy Efficacy During Pulp Therapy of the Mandibular First Permanent Molars in Children June 2022 August 2022
NCT04585438 Unknown status Phase 4 Evaluation of Trans-mucosal Bio-adhesive Discs of Diclofenac Potassium on the Anesthetic Success and Postoperative Pain in Patients With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial September 21, 2021 September 22, 2022
NCT02920606 Unknown status N/A Pulpotomy as a Treatment of Irreversible Pulpitis April 2016 June 2024
NCT02940405 Unknown status N/A Ketorolac Premedication for Anesthetic Efficiency of IANB & Postendodontic Pain in Teeth With Irreversible Pulpitis January 2017 January 2018
NCT04243733 Unknown status N/A MTA vs CEM Pulpotomy in Young Permanent Molars October 10, 2018 January 10, 2021
NCT04573374 Unknown status N/A Comparing the Outcome of Pulpotomy Using Biodentine and Portland Cement in Mature Cases With Irreversible Pulpitis: Randomized Clinical Trial November 2020 August 2022
NCT04040127 Withdrawn Phase 2 Residual Dental Pulp Tissue and Cord Blood Stem Cells September 1, 2019 February 28, 2020