Onychomycosis

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Information
Disease name
Onychomycosis
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT05279846 Active, not recruiting Phase 3 A Vehicle-controlled Study of Topical MOB015B in the Treatment of Distal Subungual Onychomycosis (DSO) May 9, 2022 March 2024
NCT05482763 Active, not recruiting Mycosis Culture Collection From Dermatological Isolated July 20, 2022 December 25, 2025
NCT00356915 Completed Phase 3 Itraconazole Tablets Vs. Itraconazole Capsules vs. Placebo in Onychomycosis of the Toenail. July 2006 October 2008
NCT00385502 Completed Phase 2 A Trial of the Safety and Efficacy of EcoNail™ in the Treatment of Fungus Infections of the Great Toenail September 2006 June 2008
NCT00443820 Completed Phase 3 Efficacy Safety, and Tolerability of Topical Terbinafine in Patients With Mild to Moderate Toenail Fungus of the Big Toenail December 2006 June 2008
NCT00443898 Completed Phase 3 Efficacy, Safety, and Tolerability of Topical Terbinafine in Patients With Mild to Moderate Toenail Fungus of the Big Toenail December 2006
NCT00453271 Completed Phase 2 Treatment of Mild to Moderate Distal Subungual Onychomycosis of the Toenail January 2007 October 2008
NCT00459537 Completed Phase 3 Efficacy, Safety and Tolerability of Topical 10% Terbinafine Hydrogen Chloride Versus 5% Amorolfine Nail Lacquer in Patients With Mild to Moderate Toenail Onychomycosis March 2007 January 2009
NCT00491764 Completed Phase 2 A Study to Evaluate Efficacy and Safety of Four Posaconazole Regimens With Placebo and Terbinafine in the Treatment of Toenail Onychomycosis (Study P05082AM2)(COMPLETED) June 2007 December 2008
NCT00602251 Completed N/A Bioequivalency Study of Terbinafine Tablets Under Fed Conditions March 2004 April 2004
NCT00602342 Completed N/A Bioequivalency Study of Terbinafine Tablets Under Fasting Conditions March 2004 April 2004
NCT00679523 Completed Phase 2 Safety and Efficacy Study of Subjects With Onychomycosis of the Great Toenail November 2005 February 2007
NCT00679601 Completed Phase 2 Absorption and Systemic Study of AN2690 in Patients With Moderate to Severe Onychomycosis (ADME II) March 31, 2007 May 31, 2007
NCT00680095 Completed Phase 1 Cumulative Irritation Test January 22, 2007 February 19, 2007
NCT00680134 Completed Phase 2 Safety and Efficacy Evaluation of Topically Applied AN2690 Solutions for Subjects With Onychomycosis June 30, 2006 August 31, 2007
NCT00680160 Completed Phase 2 Absorption and Systemic Study of AN2690 in Patients With Moderate to Severe Onychomycosis (ADME I) April 30, 2006 May 9, 2007
NCT00730405 Completed Phase 2 Efficacy and Safety Study of 4 Dose Regimens of Oral Albaconazole in Subjects With Distal Subungual Onychomycosis July 16, 2008 February 19, 2010
NCT00768768 Completed Phase 1 Iontophoretic Application of Terbinafine Gel to the Large Toe Nail October 2008 March 2009
NCT00777868 Completed Phase 2 A Dose-Ranging Study Evaluating the Safety and Efficacy of IDP-108 in Patients With Onychomycosis October 2007 April 2009
NCT00781820 Completed Phase 3 Comparative Efficacy of Bifonazole Cream vs Placebo After Nail Ablation With Urea Paste October 2008 January 2010
NCT00791219 Completed Phase 2 Study Comparing SUBA™-Itraconazole With SPORANOX® (Itraconazole) in the Treatment of Onychomycosis November 2008 December 2010
NCT00935649 Completed Phase 2/Phase 3 PinPointe FootLaser for the Treatment of Onychomycosis June 2009 November 2010
NCT00253305 Completed Phase 2 Topical Gel Anti-Fungal Agent for Tinea Unguium September 2005
NCT02343627 Completed Phase 2 Safety and Efficacy of NVXT Solution in Mild-to-Moderate Fungal Infection of the Toe Nail December 2014 January 2016
NCT02355899 Completed Phase 2 Evaluation of the Suitability of PD P 506 A in the PDT of Distal Subungual Onychomycosis (DSO) of the Great Toenail. January 2015 August 23, 2017
NCT02445495 Completed Chart Review of the Efficacy of the GenesisPlus 1064 nm Nd:YAG Laser in the Treatment of Onychomycosis November 2013 November 2014
NCT02464826 Completed Phase 4 A Pilot Study - Safety and Efficacy of Nailprotex® for Onychomycosis Treatment July 2015 June 2016
NCT02547701 Completed Phase 3 Clinical Trial on Onychomycosis With P-3058 Nail Solution in Pediatric Population August 2014 September 2017
NCT02549001 Completed Phase 3 Study to Evaluate the Efficacy and Safety of P-3058 10% Nail Solution in the Treatment of Toenail Onychomycosis August 20, 2015 September 17, 2018
NCT02588599 Completed N/A A Retrospective Analysis of the Effects of Low Level Laser Therapy on Toenail Onychomycosis October 2015 October 2015
NCT02714504 Completed N/A Anti-mold Azole in the Prophylaxis for Invasive Fusariosis August 2008 December 2014
NCT02798380 Completed Phase 2 Efficacy, Safety, and Tolerability of HTS-519 Insert in Patients With Toenail Fungus of the Big Toenail July 2016 October 2018
NCT02812771 Completed Phase 4 Safety and Pharmacokinetics of Efinaconazole Topical Solution in Subjects With Mild to Severe Onychomycosis August 4, 2016 January 14, 2019
NCT02933879 Completed Phase 2 Randomized, Placebo-Controlled, Double-Blind, Parallel-Group, Multi-Site Phase 2b Clinical Study March 21, 2016 June 21, 2018
NCT03098615 Completed Phase 4 Study Evaluating the Effect of Jublia on Dermatophytomas September 2015 July 2018
NCT03168841 Completed Phase 3 Efficacy and Safety of Efinaconazole 10% Solution in the Treatment of Onychomycosis in Diabetic Patients June 6, 2017 January 9, 2019
NCT03216200 Completed N/A Early Feasibility Study to Evaluate the Efficacy of the RenewalNail™ Plasma Treatment System in Patients With Onychomycosis (Fungal Nail) July 7, 2017 July 10, 2018
NCT03244280 Completed Phase 1 A Study of the Systemic Absorption of MOB015B December 16, 2017 April 23, 2018
NCT03289871 Completed N/A Clinical Evaluation of the Efficacy of a Medical Device in Treatment of Toenail Onychomycosis January 2015 November 2015
NCT03405818 Completed Phase 4 An Evaluation of the Safety and Pharmacokinetics of Tavaborole Topical Solution for the Treatment of Fungal Disease of the Toenail in Children and Adolescents October 22, 2015 July 27, 2017
NCT03814343 Completed Phase 4 Topical Amphotericin B in 30% Dimethylsulphoxide in Treating of Non-dermatophytes Onychomycosis January 15, 2019 November 30, 2020
NCT04327622 Completed Prevalence and Risk Evaluation of Diabetic Complications of the Foot in A Large Canadian Population March 3, 2020 June 30, 2020
NCT04940520 Completed Phase 1 Alpha-bisabolol for Onychomycosis Treatment June 1, 2020 May 1, 2021
NCT04993066 Completed N/A Clinical Evaluation to Assess the Safety and Efficacy of GentleMax Pro Plus November 12, 2020 April 27, 2023
NCT05089409 Completed Phase 1 A Study of ATB1651 in Adults With Mild to Moderate Onychomycosis March 4, 2022 September 20, 2023
NCT05560841 Completed N/A Effectiveness and Safety of Nailner Brush 2in1 in Onychomycosis July 28, 2022 April 10, 2023
NCT05578950 Completed Phase 1 Comparative Study Between Pulse Therapy With Oral Itraconazole Versus Continuous Oral Terbinafine Therapy for Treatment of Onychomycosis March 1, 2022 August 31, 2022
NCT05626270 Completed N/A Human Factors Testing for OTC Use of the Erchonia® LunulaLaser June 4, 2021 December 23, 2022
NCT00941317 Completed Phase 1 Single-blind Evaluation of Device to Nail Micro-drilling in Onychomycosis July 2009 September 2009
NCT00960089 Completed N/A Efficacy Study of LIQUICURE™ to Treat Toe Nail Fungus July 2008 October 2010
NCT01007708 Completed Phase 3 The Safety and Efficacy of Topical IDP-108 Versus Vehicle in Patients With Onychomycosis November 2009 December 2011
NCT01008033 Completed Phase 3 Safety and Efficacy of Topical IDP-108 Versus Vehicle in Patients With Onychomycosis November 2009 December 2011
NCT01014962 Completed Phase 1 A Study of the Effects of Increasing Doses of a Drug for the Treatment of Nail Fungus August 24, 2009 December 4, 2009
NCT01039883 Completed Phase 1 A Study to Compare the Blood Levels of Albaconazole in Healthy Subjects Who Have Received a Single Dose of 400 mg Albaconazole as a Tablet Versus Albaconazole as a Capsule November 23, 2009 January 20, 2010
NCT01044381 Completed Phase 1/Phase 2 Open-Label Pharmacokinetics (PK)/Safety Study of Luliconazole Solution, 10% in Distal Subungual Onychomycosis December 2010 May 2011
NCT01080079 Completed Phase 2 Efficacy and Safety Study of Iontophoretic Application of Terbinafine Gel in Subjects With Onychomycosis May 2010 June 2012
NCT01180491 Completed N/A A Clinical Investigation on Early Visible Effects of Application of K101 During 8 Weeks on Discoloured and Deformed Nails Resulting From Onychomycosis September 2010 November 2010
NCT01246518 Completed Phase 2 Efficacy and Safety of Two Treatment Regimens of Topical MOB015 in Adults With Distal Subungual Onychomycosis December 2010 October 2012
NCT01278394 Completed Phase 2 Safety and Efficacy Study of Subjects With Onychomycosis of the Great Toenail March 2007 July 2008
NCT01400594 Completed Phase 2 Safety & Efficacy Study of HTU-520 in the Treatment of Distal Subungual Onychomycosis of the Toenail July 2011 January 2013
NCT01419847 Completed Phase 4 Topical Penlac Nail Lacquer for Onychomycosis in Children March 2002 May 2006
NCT01452490 Completed N/A Diode Laser Treatment of Onychomycosis October 2011 August 2013
NCT01484145 Completed Phase 2 Deposition of Terbinafine After Iontophoretic Application of ETS Terbinafine Gel in Subjects With Distal Subungual Onychomycosis in the Great Toenail December 2011 April 2012
NCT01534689 Completed N/A Study of the Use of Low Level Laser Light Therapy to Treat Toenail Fungus April 2011 April 2012
NCT01666002 Completed N/A Treatment of Onychomycosis Using a 0.65 Millisecond Pulsed Nd:YAG 1064 nm Laser September 2011 November 2013
NCT01790165 Completed Phase 2 TDT 067 Open Label Multi-Dose Onychomycosis Study December 2009 June 2012
NCT01819051 Completed N/A Pilot Study to Evaluate Plasma Treatment of Onychomycosis March 2013 March 2015
NCT01841996 Completed Phase 1 Pharmacokinetics and Safety Study of ME1111 in Moderate to Severe Onychomycosis Patients March 2013
NCT01851590 Completed Phase 4 Resin vs. Amorolfine vs. Terbinafine Treatment in Onychomycosis October 2013 October 2014
NCT01915355 Completed N/A Pulsed Dye Laser Treatment of Onychomycosis July 2013 July 2015
NCT01996995 Completed N/A Laser Therapy for Onychomycosis in Patients Wih Diabetes at Risk for Diabetic Foot Complications March 2015 July 7, 2017
NCT02022215 Completed Phase 2 Efficacy and Safety Study of ME1111 in Patients With Onychomycosis December 19, 2013 March 1, 2016
NCT02242019 Completed N/A Study of Erchonia Low Level Laser Light Therapy to Treat Toenail Fungus February 2013 February 2014
NCT02267356 Completed Phase 2 A Study to Evaluate the Efficacy and Safety of Oral VT-1161 in Patients With Onychomycosis of the Toenail February 17, 2015 July 7, 2017
NCT02270697 Completed Evaluation of an Oligonucleotide Array for Rapid Identification of Dermatophytes in Clinical Specimens March 2012 March 2014
NCT05809297 Not yet recruiting Phase 4 Diode Laser and Photodynamic Therapy Vs. Ciclopirox. September 1, 2023 December 31, 2024
NCT06175013 Not yet recruiting N/A Evaluation of a Combination of Two Medical Devices and One Device Use in the Treatment of Toenail Onychomycosis June 2024 July 2024
NCT06327295 Not yet recruiting Phase 2 A Study of ATB1651 in Adults With Mild to Moderate Onchomycosis March 30, 2024 January 30, 2026
NCT06254027 Not yet recruiting N/A Clinical Investigation for the Evaluation of Efficacy and Safety of Two Medical Devices for Onychomycosis Treatment March 2024 September 2025
NCT06074315 Recruiting N/A Evaluation of the Effectiveness of Nail Genesis DLSO Product for Onychomycosis October 1, 2023 January 2025
NCT05491603 Suspended Phase 2 A Trial to Evaluate the Safety and Efficacy of DBI-001 Gel, DBI-002 Gel, and Aqueous Gel in Subjects With Onychomycosis November 2023 November 30, 2023
NCT01208168 Terminated Phase 3 Safety & Efficacy of NAB001 in the Treatment of Mild to Moderate Onychomycosis of the Toenails September 2010 July 2012
NCT01208129 Terminated Phase 3 Safety and Efficacy of NAB001 in the Treatment of Mild to Moderate Onychomycosis of the Toenails September 2010 July 2012
NCT01145807 Unknown status Phase 3 TDT 067 Onychomycosis Study April 2010 August 2012
NCT01615913 Unknown status Phase 1 Optimizing the Treatment of Toenail Onychomycosis Using a New Transdermal Patch Combined With Terbinafine/Ketoconazole April 2012 June 2013
NCT00233493 Unknown status Spread of Dermatophytes Among Families March 2005 February 2006
NCT05415852 Unknown status N/A Lasers in Onychomycosis June 25, 2022 September 15, 2022
NCT00771732 Unknown status Phase 2 Using Light Therapy to Treat Toe Nail Fungus May 2008 December 2009
NCT01014637 Unknown status Phase 4 Efficacy, Safety and Cost-effectiveness of a Sequential Therapy With RV4104A Ointment, Ciclopiroxolamine Cream and Ciclopirox Film-forming Solution Compared With Amorolfine Nail Lacquer in Dermatophytic Onychomycosis August 2009 September 2011
NCT02644551 Unknown status Phase 2 The Efficacy of CELEXT07 in the Treatment of Toenail Onychomycosis November 2016 September 2018
NCT02724384 Unknown status N/A Evaluating the Safety, Tolerability and Preliminary Efficacy of Plasma in Improving the Appearance of Onychomycosis March 2016 February 2019
NCT02019446 Unknown status N/A Laser Treatment for Onychomycosis in Diabetes July 2018 December 2021
NCT00808366 Unknown status N/A Efficacy and Safety of RV4104A Ointment in Onychomycosis October 2008 October 2009
NCT02961634 Unknown status Phase 3 Study Efficacy and Safety in Comparative Use of Investigational Product Adjuvant Treatment in Onychomycosis April 2017 August 2017
NCT05202366 Unknown status An Open-label Study Evaluating the Effectiveness of CGB-400 Topical Gel for Fungal Infection February 8, 2022 September 15, 2022
NCT00776464 Unknown status Phase 2/Phase 3 Treating Onychomychosis November 2008 January 2010
NCT02436291 Unknown status Phase 4 Evaluation of the Efficacy of CURE-EX Treatment in Onychomycosis October 2014 December 2015
NCT01528813 Unknown status Phase 2 Erbium-doped Yttrium Aluminium Garnet Laser(Er:Yag)Associated With Amorolfine Lacquer in the Treatment of Onychomycosis February 2012 December 2013
NCT05390190 Unknown status N/A Radiofrequency in Onychomycosis July 1, 2022 October 1, 2022
NCT00938925 Withdrawn N/A Effectiveness of Podiatry Care on Onychomycosis (EPOCAON) October 2009 March 2017
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0012203
MeSH unique ID (MeSH (Medical Subject Headings))
D014009