Severe asthma
Information
- Disease name
- Severe asthma
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT04612556 | Active, not recruiting | Efficacy of Mepolizumab in Severe Asthmatics on a Long Term (MESILICO) | January 22, 2021 | March 15, 2025 | |
| NCT02114034 | Active, not recruiting | Cohort Analysis of Clinical and Biological Severe Childhood Asthma | November 12, 2013 | November 2032 | |
| NCT05603845 | Active, not recruiting | Patient-Reported OUTcomes of Benralizumab in Real-World Use in Severe EosiNophilic Asthma Patients | February 20, 2023 | March 31, 2025 | |
| NCT06389058 | Active, not recruiting | Using NLP and Neural Networks to Autonomously Identify Severe Asthma and Determine Study Eligibility in a Large Healthcare System | May 1, 2023 | November 2026 | |
| NCT02975284 | Active, not recruiting | Unraveling Targets of Therapy in Bronchial Thermoplasty in Severe Asthma (TASMA) Extension Study | August 2015 | September 2024 | |
| NCT03074942 | Completed | Phase 2 | Reslizumab in Patients With Severe Asthma Who Failed to Respond to Omalizumab | April 20, 2017 | April 30, 2018 |
| NCT03361111 | Completed | BIOmarkers in Severe AsthMa Patients on Omalizumab Treatment | April 4, 2013 | December 30, 2018 | |
| NCT06239441 | Completed | Effectiveness of Anti-IL-5/IL5R Inhibitors | February 16, 2021 | November 29, 2023 | |
| NCT03387722 | Completed | Assessment of Treatment Patterns of Severe Asthmatic Patients Across the Gulf Region - SevEos Study | December 31, 2017 | January 3, 2019 | |
| NCT01350336 | Completed | N/A | Bronchial Thermoplasty in Severe Persistent Asthma | April 7, 2011 | March 17, 2020 |
| NCT00621946 | Completed | Phase 4 | Treatment of Outpatients With Severe Asthma and Moderate or Severe Major Depressive Disorder | March 2008 | March 2010 |
| NCT06024902 | Completed | Clinical Characteristics of Severe Childhood Asthma | January 1, 2021 | December 31, 2022 | |
| NCT03629782 | Completed | Characterisation of Patients With Severe Asthma in Primary and Secondary Care Settings in Europe Reported to be Eligible for Biological Therapy | April 26, 2018 | July 31, 2020 | |
| NCT05616338 | Completed | N/A | Modeling Bronchial Epithelium in Severe Asthma With Human Induced Pluripotent Stem Cells (iPSC) | November 29, 2022 | March 16, 2023 |
| NCT03925415 | Completed | BRazilian Asthmatics Patients EOSinophilic Profile (BRAEOS) | January 24, 2019 | October 15, 2019 | |
| NCT03931954 | Completed | Prevalence of the Eosinophilic Phenotype Among Severe Asthma Patients | May 15, 2019 | November 26, 2020 | |
| NCT04022447 | Completed | Dupilumab for Severe Asthma in a Real Life Setting | August 10, 2018 | April 2, 2019 | |
| NCT04031261 | Completed | National Validation and Sensitivity to Change of the SAQ | April 10, 2019 | March 23, 2020 | |
| NCT04272463 | Completed | ChAracterisation of ItaliaN Severe Uncontrolled Asthmatic patieNts Key Features When Receiving Benralizumab | March 13, 2020 | July 15, 2020 | |
| NCT05331755 | Completed | Real Life Experience Survey of Dupilumab in the Netherlands | April 1, 2021 | December 31, 2022 | |
| NCT05147155 | Completed | Impulse Oscillometry Measurements in Severe Eosinophilic Asthmatics Before and After Anti-IL-5 Factor Initiation | April 19, 2021 | October 23, 2023 | |
| NCT04648839 | Completed | Observational Retrospective Study on Clinical Outcomes of Patients Receiving Benralizumab in Spain. | February 16, 2021 | July 16, 2021 | |
| NCT03065920 | Completed | African Severe Asthma Program: A Research Network for Characterisation of Severe Asthma in Africans (ASAP) | April 2016 | December 31, 2019 | |
| NCT05576454 | Completed | Phase 1 | Evaluate the Pharmacokinetics of BAT2606 Injection in Healthy Chinese Male Subjects | September 20, 2022 | June 19, 2023 |
| NCT04221802 | Completed | Patient-reported Outcomes in Real-world Use of Benralizumab in Patients With Severe Eosinophilic Asthma in Belgium | December 23, 2019 | May 13, 2024 | |
| NCT04048343 | Completed | Phase 3 | Long-term Safety of Tezepelumab in Japanese Subjects With Inadequately Controlled Severe Asthma | June 10, 2019 | March 18, 2021 |
| NCT06421402 | Enrolling by invitation | K-HEALTH in AIR - Barcelona Pilot - Cohort | October 13, 2023 | August 31, 2026 | |
| NCT05762627 | Not yet recruiting | Severe Eosinophilic Asthma Phenotypes During Childhood Have Various Origins | March 2023 | March 2027 | |
| NCT06455462 | Recruiting | Patient Characteristics, Treatment Patterns and Outcomes of Patients Enrolled in the Tezepelumab Patient Access Programme; a Retrospective, Observational Medical Chart Review Conducted in UK Severe Asthma Centres | April 22, 2024 | September 23, 2024 | |
| NCT03435237 | Recruiting | Phenotyping Asthma for Bronchial Thermoplasty | May 10, 2021 | December 2024 | |
| NCT03476109 | Recruiting | Phase 4 | Study of Magnitude and Prediction of Response to Omalizumab and Mepolizumab in Adult Severe Asthma. | May 10, 2019 | December 31, 2024 |
| NCT03984253 | Recruiting | Swiss Severe Asthma Register | May 13, 2019 | February 28, 2034 | |
| NCT04334031 | Recruiting | N/A | Deployment o the Multidisciplinary Prospective Cohort Imminent | July 20, 2020 | July 2031 |
| NCT04520165 | Recruiting | Effect of Biologicals on Alternative Functions of Eosinophils in Severe Asthma | September 1, 2020 | August 31, 2025 | |
| NCT04565483 | Recruiting | Phase 4 | Predictive Signature of Benralizumab Response | October 11, 2021 | November 2026 |
| NCT04680117 | Recruiting | N/A | Defining the Severe Paediatric Asthma Endotype | June 15, 2021 | January 2025 |
| NCT04714567 | Recruiting | Portuguese Severe Asthma Registry: Getting Answers for Severe Asthma Patients | May 1, 2021 | December 2022 | |
| NCT05018299 | Recruiting | Phase 2 | Evaluate the Efficacy and Safety of FB704A in Adult With Severe Asthma | September 30, 2021 | September 30, 2025 |
| NCT05472324 | Recruiting | Phase 2 | Evaluate the Efficacy and Safety of TQC2731 Injection in Patients With Severe Asthma. | September 23, 2022 | October 2024 |
| NCT05946421 | Recruiting | The BASA Study: Breath Analysis for Severe Asthma Patients | July 4, 2023 | September 4, 2024 | |
| NCT06035289 | Recruiting | Register Schweres Asthma - German Asthma Net e.V. | November 1, 2011 | November 1, 2026 | |
| NCT06126692 | Recruiting | 3TR Asthma Biologics Cohort (ABC) Study | January 10, 2022 | August 2033 | |
| NCT06196879 | Recruiting | Phase 2 | A Study to Investigate the Efficacy and Safety of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALIANT) | February 27, 2024 | June 11, 2026 |
| NCT06283290 | Recruiting | PROPE Severe Asthma Study in Egypt | March 12, 2024 | July 31, 2024 | |
| NCT05164939 | Unknown status | Precision Medicine Intervention in Severe Asthma (PRISM) Study | May 1, 2020 | December 31, 2022 | |
| NCT02038374 | Unknown status | N/A | Clinico-biological Correlation of Severe Asthma in Children | November 2013 | April 2015 |
| NCT05032209 | Unknown status | Follow-up of Children With Severe Asthma at Adult Age | July 12, 2021 | July 12, 2022 | |
| NCT04463836 | Unknown status | Phenotyping Circulating and Lung Resident Eosinophils in Severe Asthma (P-CLESA) | September 1, 2020 | August 31, 2023 | |
| NCT04438408 | Unknown status | National Survey on Care Pathway and Quality of Life in Patients With Severe Asthma According to Their Phenotype. | September 1, 2020 | December 1, 2021 | |
| NCT04045587 | Unknown status | International Severe Asthma Registry: Canadian Cohort | November 6, 2018 | December 2023 | |
| NCT03608566 | Unknown status | Russian Severe Asthma Registry | March 30, 2018 | December 31, 2022 | |
| NCT03377920 | Unknown status | N/A | Predictive Value of Spirometric PIF to Produce PIF Rate Needed for the Use of Current DPI's. | October 12, 2017 | September 2019 |
| NCT03532685 | Unknown status | N/A | Clinical, Inflammatory and Functional Evaluation of a Population of Severe and Obese Asthmatics: Follow up | May 2018 | February 2019 |
| NCT01961258 | Unknown status | "SEVERE ASTHMA" in the COMMUNITY | June 2015 | June 2016 | |
| NCT04914078 | Unknown status | Severe Asthma Exacerbations and Mepolizumab Treatment | September 21, 2021 | December 1, 2023 | |
| NCT04980755 | Unknown status | N/A | Adapting Body Reprogramming for Severe Asthma: a Feasibility Study | July 28, 2021 | June 30, 2022 |
| NCT05001529 | Unknown status | Phase 4 | Flow Cytometry Analysis of Eosinophils in Severe Asthma Patients. | March 18, 2021 | March 2023 |
| NCT04108962 | Withdrawn | Phase 4 | Benralizumab in the Treatment of Patients With Severe Asthma With ABPA | December 23, 2019 | October 1, 2021 |
| NCT02433535 | Withdrawn | Phase 2 | Trial of Simvastatin for the Treatment of Severe Asthma | December 2013 | August 22, 2017 |
| NCT03784781 | Withdrawn | Type 2 Innate Lymphoid Cells in Severe Pediatric Asthma | June 9, 2016 | April 2020 |