Hypertriglyceridemia
Information
- Disease name
- Hypertriglyceridemia
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05953064 | Active, not recruiting | N/A | Effects of DHA-NAT on Postprandial Lipidaemia in Healthy Male Subjects | January 1, 2023 | April 1, 2024 |
| NCT05069298 | Active, not recruiting | N/A | Effect of Silibinin(A) as a Potential Anti-obesity Agent | January 12, 2023 | December 21, 2023 |
| NCT05610280 | Active, not recruiting | Phase 3 | A Study of Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe Hypertriglyceridemia | November 21, 2022 | June 2025 |
| NCT04239950 | Active, not recruiting | Phase 3 | Efficacy of Ethyl Icosapentate in Patients With Severe Hypertriglyceridemia | May 9, 2020 | December 2023 |
| NCT05457439 | Active, not recruiting | N/A | Sustainable-psycho-nutritional Intervention Program and Its Effects on Health Outcomes and the Environment | October 1, 2022 | December 2023 |
| NCT00086437 | Completed | Pharmacogenetics of Hypertriglyceridemia in Hispanics | July 2004 | January 2010 | |
| NCT00092560 | Completed | Phase 3 | Two Investigational Drugs in Patients With Mixed Hyperlipidemia (0653-036) | December 2002 | December 2003 |
| NCT00092573 | Completed | Phase 3 | Study of Ezetimibe and Fenofibrate in Patients With Mixed Hyperlipidemia (0653-036)(COMPLETED) | April 2003 | November 2004 |
| NCT00093899 | Completed | Phase 3 | A Study to Evaluate an Investigational Drug in Patients With Mixed Hyperlipidemia (0653A-071)(COMPLETED) | November 2004 | September 2005 |
| NCT00108511 | Completed | Phase 1 | Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides | October 2004 | September 2007 |
| NCT00109603 | Completed | N/A | Effect of Tenofovir Disoproxil Fumarate on Lipid Levels in HIV Infected Adults on Stable Anti-HIV Drug Therapy | May 2005 | November 2007 |
| NCT00134498 | Completed | Phase 3 | A Study Comparing The Efficacy & Safety Of Torcetrapib/Atorvastatin And Atorvastatin In Subjects With High Triglycerides | February 2005 | November 2006 |
| NCT00186537 | Completed | N/A | Comparing Tricor, Avandia, or Weight Loss to Lower Cardiovascular Risk Factors in People With High Triglycerides. | September 2003 | September 2008 |
| NCT00246376 | Completed | N/A | Diet, Exercise, Niacin, and Fenofibrate to Reduce Heart Disease Risk Factors in Individuals With HIV Lipodystrophy or Dyslipidemia | January 2004 | February 2012 |
| NCT00246402 | Completed | N/A | Acipimox to Improve Hyperlipidemia and Insulin Sensitivity Associated With HIV | September 2002 | August 2006 |
| NCT00246636 | Completed | Phase 4 | Evaluation of Efficacy and Safety of Omacor (Omega-3-acid Ethyl Esters) as Add-on Therapy in Hypertriglyceridemic Subjects Treated With Antara (Fenofibrate) Followed by an 8-week Extension | October 2005 | March 2007 |
| NCT00246701 | Completed | Phase 3 | Evaluation of Efficacy and Safety of Combined Omacor (Omega-3-acid Ethyl Esters) and Simvastatin Therapy in Hypertriglyceridemic Subjects | November 1, 2005 | June 1, 2006 |
| NCT00286234 | Completed | Phase 4 | Niacin, N-3 Fatty Acids and Insulin Resistance | October 2007 | December 2008 |
| NCT00346697 | Completed | Phase 4 | Omega-3 Fatty Acids for High Triglycerides in HIV-infected Patients | October 2006 | April 2010 |
| NCT03693131 | Completed | Phase 3 | Efficacy of MND-2119 in Participants With Hypertriglyceridemia | October 27, 2018 | June 29, 2019 |
| NCT00018720 | Completed | Regulation of Sterol Homeostasis | April 1996 | December 2000 | |
| NCT00046267 | Completed | N/A | Niacin for Treatment of Elevated Cholesterol and Triglycerides in HIV-Infected Patients | ||
| NCT00049881 | Completed | Genetic Determinants:Low HDL, High Triglycerides, Obesity | April 2002 | March 2004 | |
| NCT00076518 | Completed | Phase 2 | The Effect of Fish Oil Plus Fenofibrate on Triglyceride Levels in People Taking Highly Active Antiretroviral Therapy (HAART) | September 2005 | |
| NCT02898142 | Completed | N/A | Intestines and Liver Contribution to Fasting Postprandial Hypertriglyceridemia | February 2012 | September 2015 |
| NCT02911753 | Completed | N/A | Feasibility and Acceptability of a Beverage Intervention for Hispanic Adults | June 2016 | August 2017 |
| NCT02924558 | Completed | N/A | Metabolic Effects of Egg Protein and Unsaturated Fat Intakes in Subjects With Hypertriglyceridemia | February 2015 | February 2016 |
| NCT02926027 | Completed | Phase 4 | Effect of Vascepa on Improving Coronary Atherosclerosis in People With High Triglycerides Taking Statin Therapy | March 28, 2017 | August 15, 2020 |
| NCT02989753 | Completed | Phase 1/Phase 2 | Effects of Two Herbal Dietary Supplements on Lipid Metabolism in Moderate Hypercholesterolemia and Hypertriglyceridemia | January 2017 | July 2018 |
| NCT03120299 | Completed | Phase 4 | The Effect of Omega-3 FA on Hypertriglyceridemia in Patients With T2DM(OCEAN) | May 1, 2017 | June 1, 2021 |
| NCT03216057 | Completed | N/A | Safety and Efficacy of Omega-3 Free Fatty Acids in Adolescents With Obesity and Hypertriglyceridemia. | May 20, 2008 | November 22, 2016 |
| NCT03262610 | Completed | Phase 2 | Setmelanotide in a Single Patient With Partial Lipodystrophy | August 15, 2017 | January 31, 2018 |
| NCT03361501 | Completed | Phase 3 | A Phase 3 STudy of CaPRe in LOwering Very hiGh TriglYcerides (TRILOGY 2) | February 1, 2018 | January 9, 2020 |
| NCT03371355 | Completed | Phase 2 | Study of ISIS 703802 in Participants With Hypertriglyceridemia, Type 2 Diabetes Mellitus, and Nonalcoholic Fatty Liver Disease | December 21, 2017 | February 24, 2020 |
| NCT03385239 | Completed | Phase 2 | Study of ISIS 678354 (AKCEA-APOCIII-LRx) in Participants With Hypertriglyceridemia and Established Cardiovascular Disease (CVD) | January 30, 2018 | February 25, 2020 |
| NCT03398005 | Completed | Phase 3 | A Phase 3 STudy of CaPRe In LOwering Very hiGh TriglYcerides (TRILOGY 1) | January 23, 2018 | November 20, 2019 |
| NCT03415152 | Completed | A Prospective Observational Program Using Digital Technology Tools to Enhance Patient Adherence to Omacor Therapy | January 24, 2018 | July 1, 2019 | |
| NCT03508687 | Completed | Phase 1/Phase 2 | Study of Gemcabene in Adults With FPLD | March 13, 2018 | July 31, 2019 |
| NCT03591588 | Completed | N/A | Effects of Diet Interventions on Monocytes in Metabolic Syndrome | April 1, 2016 | March 31, 2020 |
| NCT03649269 | Completed | N/A | PC-300 Tea Effect on Triglyceride Levels | January 1, 2014 | December 31, 2014 |
| NCT00005442 | Completed | Re-evaluating Triglycerides in Coronary Heart Disease | June 1994 | May 2000 | |
| NCT03747224 | Completed | Phase 1 | Study of ARO-ANG3 in Healthy Volunteers and in Dyslipidemic Patients | January 7, 2019 | May 17, 2021 |
| NCT03783377 | Completed | Phase 1 | Study of ARO-APOC3 in Healthy Volunteers, Hypertriglyceridemic Patients and Patients With Familial Chylomicronemia Syndrome (FCS) | March 8, 2019 | February 11, 2021 |
| NCT03846908 | Completed | N/A | Postprandial Lipid Metabolism in Patients With Hypertriglyceridemia and Normo-lipidemic Controls: Medium Chain Fatty Acids (MCT) in Comparison to Long-chain, Saturated Fatty Acids (SFA) and Mono-unsaturated Fatty Acids (MUFA) | February 1, 2019 | March 31, 2021 |
| NCT03929198 | Completed | N/A | Translation of Pritikin Program to the Community | September 27, 2018 | December 1, 2018 |
| NCT04128839 | Completed | N/A | Impacts of Aronia on Inflammation and the Gut Microbiome | April 27, 2019 | December 27, 2021 |
| NCT04143971 | Completed | N/A | Intermittent Fasting in Hypertriglyceridemic Overweight or Obese Subjects | December 2, 2019 | May 20, 2020 |
| NCT04177680 | Completed | Phase 2 | Pharmacodynamic Effects of a Free-Fatty Acid Formulation of Omega-3 Pentaenoic Acid in Adults With Hypertriglyceridemia | June 3, 2020 | January 18, 2021 |
| NCT04221217 | Completed | Phase 3 | Long-term Safety and Efficacy Study of MND-2119 in Patients With Hypertriglyceridemia | February 14, 2020 | July 14, 2021 |
| NCT04236518 | Completed | N/A | Nutritional Transitions to More Plant Proteins and Less Animal Proteins: Understanding the Induced Metabolic Reorientations and Searching for Their Biomarkers (ProVegOmics) | August 27, 2020 | August 5, 2022 |
| NCT04283448 | Completed | N/A | Impacts of Lentils on Metabolism and Inflammation | May 22, 2020 | November 19, 2023 |
| NCT04630366 | Completed | Phase 1 | A Phase 1, First Time in Humans Study of NST-1024 | October 27, 2020 | June 20, 2022 |
| NCT04650152 | Completed | Study to Assess Tricor Therapy Effectiveness in Patients With Metabolic Syndrome (TRISTAN) | October 27, 2020 | November 12, 2021 | |
| NCT04756180 | Completed | Phase 3 | An Efficacy and Safety Study of Omega-3-acid Ethyl Ester in Chinese Subjects With Hypertriglyceridemia. | October 2016 | April 2019 |
| NCT04966494 | Completed | N/A | Impact of Beans and Oats Snack Bar on Hypertriglyceridemic Women | October 5, 2013 | November 2, 2015 |
| NCT04990817 | Completed | N/A | Effects of Replacing Energy From Solid Fats and Added Sugars (SoFAS) With Avocado | June 18, 2021 | April 17, 2024 |
| NCT05025943 | Completed | N/A | Omega-3 Fatty Acid Dietary Intervention (O3DI) | August 16, 2021 | March 15, 2023 |
| NCT05096455 | Completed | Hypertriglyceridemia Associated Acute Pancreatitis in Intensive Care Unit and Therapeutic Plasmapheresis | January 1, 2010 | December 31, 2020 | |
| NCT05181514 | Completed | N/A | Impact of Plasma Lipids on β Cell Function and Insulin Sensitivity | April 30, 2019 | December 1, 2021 |
| NCT05255718 | Completed | N/A | Impact of Aronia Berry Consumption on Inflammation, Metabolites, and the Gut Microbiome | April 27, 2019 | August 18, 2019 |
| NCT05295134 | Completed | N/A | Effect of Candida Rugosa Lipase on Serum Triglyceride Lowering | March 13, 2014 | November 4, 2014 |
| NCT05355402 | Completed | Phase 2 | A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Adults With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease (Established or at Increased Risk for), and/or With Severe Hypertriglyceridemia | May 9, 2022 | December 21, 2023 |
| NCT05609825 | Completed | Phase 1 | A Study of LY3875383 in Healthy Participants and Participants With Hypertriglyceridemia | November 14, 2022 | January 10, 2024 |
| NCT05685017 | Completed | Adiponectin, ICAM-1, VCAM-1 Levels and Metabolic Syndrome in Obese Adolescents | October 1, 2019 | June 30, 2020 | |
| NCT06020950 | Completed | N/A | Chia Seeds Consumption in Hypertriglyceridemia | September 18, 2023 | March 16, 2024 |
| NCT00435045 | Completed | Phase 3 | Evaluation of Efficacy and Safety of Omacor, Co-Administered With Atorvastatin, in Subjects With Hypertriglyceridemia | February 2007 | October 2007 |
| NCT00457938 | Completed | N/A | Novel Therapies for Metabolic Complications of Lipodystrophies | April 2006 | November 2014 |
| NCT00473655 | Completed | Phase 4 | Effect of Rosuvastatin on Triglyceride Levels in Mexican Hypertriglyceridemic Patients | January 2007 | February 2009 |
| NCT00504309 | Completed | N/A | Vascular and Lipid Effects of Omega-3 Fatty Acids in People With Moderately Elevated Triglycerides | July 2007 | January 2009 |
| NCT00519714 | Completed | Phase 2/Phase 3 | A Study to Evaluate the Lipid Regulating Effects of 1-Methylnicotinamide (1-MNA) | September 2007 | November 2008 |
| NCT00540111 | Completed | N/A | Effect of Soluble Fiber on Hypertriglyceridemia and Immune Profile in HIV-positive Individuals. | March 2005 | October 2007 |
| NCT00560430 | Completed | Phase 3 | Regulation of Inflammatory Parameters by Telmisartan in Hypertensive Patients | November 2007 | October 2009 |
| NCT00562575 | Completed | Phase 2 | Evaluation of Safety and Effects of SLx-4090 After Dosing for 14 Days in Subjects With High Triglycerides | May 2007 | February 2008 |
| NCT00593424 | Completed | N/A | Effect of Changing Diet on Fasting and Post Fat Load Lipoproteins | August 2002 | November 2005 |
| NCT00632840 | Completed | Phase 4 | Pharmacological Regulation of Fat Transport in Metabolic Syndrome | June 2001 | December 2007 |
| NCT00639041 | Completed | N/A | Changes in Blood Lipids After Long-term Consumption of n-3 LC-PUFA-Enriched Dairy Products | April 2006 | May 2007 |
| NCT00688857 | Completed | Phase 1 | Open-label Pharmacokinetic Study of Diazoxide Choline Coated vs. Uncoated Formulations | May 2008 | July 2008 |
| NCT00696475 | Completed | Phase 2 | Diazoxide Choline in Hypertriglyceridemia | June 2008 | March 2009 |
| NCT00728338 | Completed | N/A | Docosahexenoic Acid (DHA) Supplementation and Cardiovascular Disease in Men With High Triglycerides | June 2003 | November 2005 |
| NCT00745407 | Completed | Phase 4 | Effects of Fenofibrate on Adipocytokine Levels In Hypertriglyceridemic Patients | January 2005 | August 2008 |
| NCT00804427 | Completed | N/A | Effect of Fish Oil on Plasma Triglycerides in Adults | December 2008 | April 2010 |
| NCT00887653 | Completed | Phase 3 | Changes in Lipids and Safety of Raltegravir in HIV+ Patients With Hyperlipidemia While on Current Standard Therapy | May 2009 | April 2014 |
| NCT00891293 | Completed | Phase 4 | A Second Open-Label Extension of a Double-Blind, Parallel, Phase IV Study to Assess the Efficacy and Safety of Adjunctive Lovaza® (Formerly Known as Omacor®) Therapy in Hypertriglyceridemic Subjects Treated With Antara™ | March 2006 | May 2008 |
| NCT00903409 | Completed | Phase 3 | Open-Label Extension of a Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Lovaza® and Simvastatin Therapy in Hypertriglyceridemic Subjects | November 15, 2005 | June 27, 2008 |
| NCT00915902 | Completed | Phase 2/Phase 3 | Fish Oil Study for High Triglyceride Levels in Children | July 2009 | September 2012 |
| NCT00931879 | Completed | Phase 4 | Lovaza® and Microvascular Function in Type 2 Diabetes | October 2009 | July 2012 |
| NCT00937898 | Completed | N/A | Beef in an Optimal Lean Diet (BOLD) Effects on Cardiovascular Disease (CVD) Risk | August 2007 | March 2012 |
| NCT00959842 | Completed | Phase 1/Phase 2 | Effects of Lovaza on Lipoprotein Composition and Function in Mild Hypertriglyceridemia | September 2009 | February 2010 |
| NCT01003847 | Completed | Phase 4 | Differential Metabolic Effects of Fenofibrate and Fatty Acid | November 2009 | September 2010 |
| NCT01010399 | Completed | Phase 4 | Boosted Lexiva With Lovaza Adjunctive Therapy in Hypertriglyceridemic, HIV-Infected Subjects | September 2009 | November 2010 |
| NCT01023750 | Completed | Predictors of Response to Fenofibrate | January 2010 | July 2012 | |
| NCT01034540 | Completed | N/A | Effects of Prescription Omega-3 Acids on Glucose and Lipoprotein Lipids in Subjects With Hypertriglyceridemia | March 2010 | February 2011 |
| NCT01047501 | Completed | Phase 3 | Effect of AMR101 (Ethyl Icosapentate) on Triglyceride (Tg) Levels in Patients on Statins With High Tg Levels (≥ 200 and < 500 mg/dL) | December 2009 | February 2011 |
| NCT01047683 | Completed | Phase 3 | Efficacy and Safety of AMR101 (Ethyl Icosapentate) in Patients With Fasting Triglyceride (Tg) Levels ≥ 500 and ≤ 2000 mg/dL | December 2009 | July 2011 |
| NCT01088776 | Completed | Phase 2 | Omega-3 Fatty Acid Supplementation in Children | March 2010 | March 2016 |
| NCT01129050 | Completed | N/A | Effects of Omega-3 Fatty Acids on Markers of Inflammation | April 2007 | December 2008 |
| NCT01133210 | Completed | Phase 1 | Effect of Maraviroc on Metabolic Function in Obese Subjects (Phase I) | January 2011 | November 2012 |
| NCT01148004 | Completed | Phase 1 | The Influence of Ritonavir, Alone and in Combination With Lopinavir, on Fenofibric Acid Pharmacokinetics in Healthy Volunteers | May 13, 2010 | July 29, 2013 |
| NCT01150188 | Completed | N/A | Effects of Amino Acids on Regional Lipid Metabolism | June 2010 | August 2016 |
| NCT01211847 | Completed | Phase 2 | Efficacy Study of Diazoxide Choline to Treat Hypertriglyceridemia | October 2010 | December 2011 |
| NCT01245738 | Completed | Effect of Statins on Lipid Levels Following the First Acute Coronary Event (MK-0000-204) | August 2010 | December 2012 | |
| NCT01258322 | Completed | N/A | Pioglitazone Attenuates Dysmetabolism in Peritoneal Dialysis (PD) Patients | January 2008 | September 2008 |
| NCT01350973 | Completed | Phase 3 | Efficacy of TAK-085 in Participants With Hypertriglyceridemia | November 2009 | December 2010 |
| NCT01350999 | Completed | Phase 3 | Long-term Efficacy and Safety Study of TAK-085 in Participants With Hypertriglyceridemia | November 2009 | January 2011 |
| NCT01408303 | Completed | Phase 3 | [E]PANOVA Combined With a [S]TATIN in [P]ATIENTS With HYPERT[R]IGLYCER[I]DEMIA to Reduce Non-HDL CHOLES[T]EROL | August 2011 | June 2012 |
| NCT01431690 | Completed | Phase 1 | Interaction of Epanova on Warfarin Pharmacokinetic and Anticoagulant Activity and Comparison of the Effects of Epanova and Lovaza on Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) After Low-fat Meals | August 2011 | October 2011 |
| NCT01437930 | Completed | N/A | Intervention With n-3 Polyunsaturated Fatty Acids (PUFA)-Supplemented Products in Moderate Hypertriglyceridemic Patients | September 2011 | April 2012 |
| NCT01445730 | Completed | N/A | Fructose Consumption and Metabolic Dysregulation | August 2011 | June 2015 |
| NCT01455844 | Completed | Phase 2 | TRIal For Efficacy of Capre on hyperTriglyceridemiA | September 2011 | August 2014 |
| NCT01462877 | Completed | Phase 4 | A Study to Evaluate Fenofibrate Combination With Statin in Chinese Patients With Dyslipidemic | October 2011 | March 2014 |
| NCT01486433 | Completed | Phase 1 | The Effect of Multiple Doses of Epanova® on the Multiple-Dose Pharmacokinetics of Simvastatin in Healthy Normal Subjects | November 2011 | March 2012 |
| NCT01488409 | Completed | Phase 2 | Effects of Acipimox on Mitochondrial Function in Obesity | May 2012 | January 2015 |
| NCT01516151 | Completed | Phase 2 | Assess the Safety and Efficacy of NKPL66 (CaPre™) in the Treatment of Mild-to-high Hypertriglyceridemia | December 2011 | September 2013 |
| NCT01529424 | Completed | Phase 2 | Safety, Tolerability, and Pharmacokinetic Study of ISIS ApoC-III Rx in Hypertriglyceridemia | February 2012 | January 2014 |
| NCT01539616 | Completed | Phase 2 | A Clinical Trial to Evaluate the Safety and Efficacy of ZYH7 Compared to Fenofibrate in Patients With Dyslipidemia | November 2011 | August 2012 |
| NCT01556113 | Completed | N/A | Genetic Effect on Omega 3 Fatty Acids for the Treatment of Fatty Liver Disease | March 2012 | February 2017 |
| NCT01569724 | Completed | Phase 4 | Carbohydrate Metabolism Disorder Frequency in Hypertriglyceridemia Induced by Bexarotene of Cutaneous T Cell Lymphoma | January 2012 | April 2017 |
| NCT01625442 | Completed | Phase 4 | Crocus Sativus (Saffron) and Berberis Vulgaris (Barberry Fruit) in Metabolic Syndrome | January 2010 | February 2012 |
| NCT01660932 | Completed | Phase 4 | Vascular and Metabolic Effects of Omega-3 Fatty Acids | March 2011 | September 2012 |
| NCT01666041 | Completed | Phase 4 | Vascular and Metabolic Effects of Fenofibrate/Omega vs Fenofibrate | January 2012 | July 2013 |
| NCT01725646 | Completed | Phase 3 | An Efficacy and Safety Study of Omacor® in Taiwanese Hypertriglyceridemic Patients | July 2011 | August 2013 |
| NCT01737099 | Completed | N/A | Efficacy and Safety Study of DHA-O in Adults With Hypertriglyceridemia | November 2012 | November 2013 |
| NCT01749878 | Completed | Phase 1 | Study to Assess the Safety and Tolerability of Single Doses of REGN1500 | December 2012 | January 2016 |
| NCT01819636 | Completed | N/A | Effects Of Consumption Of A Highly Mineralized Sodium Bicarbonated Water On Blood Lipid Profile | March 2013 | June 2014 |
| NCT01912560 | Completed | Phase 2 | Pilot Study To Assess CAT-2003 in Patients With Hyperlipidemia | July 2013 | December 2013 |
| NCT01968720 | Completed | Phase 2 | Pilot Study To Assess CAT-2003 in Patients With Severe Hypertriglyceridemia | October 2013 | April 2014 |
| NCT02008084 | Completed | Phase 2 | A Pilot Study to Evaluate the Lipid Effects of TRIA-662 | December 2013 | October 2015 |
| NCT02009865 | Completed | Phase 3 | Epanova® for Lowering Very High Triglycerides II (EVOLVE II) | December 16, 2013 | December 23, 2014 |
| NCT02083510 | Completed | Early Phase 1 | Apolipoprotein CIII Reduction Via Colchicine | February 2014 | May 2014 |
| NCT02098278 | Completed | Phase 2 | Pilot Study To Assess CAT-2003 in Patients With Chylomicronemia | March 2014 | April 2015 |
| NCT02113163 | Completed | Phase 1 | PK Study Comparing Metformin Eicosapentaenoate to a Combined Dose of Metformin Hydrochloride and Ethyl Ester EPA | March 2014 | July 2014 |
| NCT02215694 | Completed | Phase 3 | Supplementation of Dual Probiotic Strains Reduced Fasting Triglyceride and Enhanced Apolipoprotein A-V Levels | June 2012 | March 2014 |
| NCT02250105 | Completed | Phase 2 | Trial of ARI-3037MO to Reduce Triglyceride Levels in Adults With Severe (≥500 mg/dl) Hypertriglyceridemia | September 2014 | June 2016 |
| NCT02300233 | Completed | Phase 3 | The COMPASS Study: A Study of Volanesorsen (Formally ISIS-APOCIIIRx) in Patients With Hypertriglyceridemia | February 5, 2015 | January 24, 2017 |
| NCT02310022 | Completed | Phase 1/Phase 2 | A PK and PD Study of Two Formulations of Omega-3 One Gram Capsules | November 2014 | August 2016 |
| NCT02354976 | Completed | Phase 2 | A Double-blind Randomized Placebo-controlled Study Comparing Epanova and Fenofibrate on Liver Fat in Overweight Subjects. | September 1, 2015 | May 26, 2016 |
| NCT02463071 | Completed | Phase 3 | AZD0585 Phase III Long-term Study in Japan | June 10, 2015 | March 11, 2017 |
| NCT02526121 | Completed | N/A | Effect of Therapeutic Phlebotomies on the Triglycerides Concentration in Patients With Hypertriglyceridemia and Hyperferritinemia | April 2013 | December 2015 |
| NCT02585869 | Completed | Phase 2 | Efficacy and Safety of Gemcabene in Patients With Low HDL-C and Either Normal or Elevated Triglycerides | December 1999 | June 2001 |
| NCT02681055 | Completed | Phase 2 | Open-Label Study To Evaluate MN-001 on HDL & Triglyceride in NASH & NAFLD Subjects | March 2016 | October 1, 2019 |
| NCT02709850 | Completed | Phase 1 | Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS ANGPTL3-LRx in Healthy Volunteers With Elevated Triglycerides and Participants With Familial Hypercholesterolemia | November 30, 2015 | June 26, 2017 |
| NCT02767531 | Completed | Phase 2 | Orlistat for the Treatment of Type I Hyperlipoproteinemia | December 2015 | December 31, 2022 |
| NCT02859129 | Completed | Phase 1 | Study to Evaluate the 2-Way Interaction Between Multiple Doses of Epanova™ and a Single Dose of Rosuvastatin (Crestor®) | September 2013 | November 2013 |
| NCT02868177 | Completed | Phase 2/Phase 3 | Effect of Totum-63, Active Ingredient of Valedia, on Glucose and Lipid Homeostasis on Subjects With Prediabetes | October 2016 | April 2019 |
| NCT06323252 | Not yet recruiting | N/A | A Study on the Effects of Mastiha Oil in Adults With Hypertriglyceridemia | April 1, 2024 | October 30, 2025 |
| NCT05851066 | Not yet recruiting | Phase 1 | A VSA003 Phase 1 Study in Chinese Adult Healthy Volunteers | June 2023 | December 2023 |
| NCT05487833 | Not yet recruiting | Phase 4 | Insulin and Standard Management in Hypertriglyceridemic Acute Pancreatitis | November 2022 | September 2024 |
| NCT06206759 | Not yet recruiting | Vitamin C Administration and Triglycerides Level in Critical Care Patients | May 1, 2024 | February 1, 2027 | |
| NCT06129526 | Not yet recruiting | Phase 4 | Study of the Efficacy and Safety of EPA in Patients With Type-2 Diabetes | December 2023 | December 2024 |
| NCT06220266 | Recruiting | Phase 2/Phase 3 | Effects of Phytoestrogen From Pueraria Mirifica in Improvement of Serum Lipid Parameters in Postmenopausal Women | March 2, 2024 | November 2024 |
| NCT05896254 | Recruiting | Phase 1/Phase 2 | Study of MAR001 in Adults With Metabolic Dysfunction | July 22, 2023 | November 2024 |
| NCT05245357 | Recruiting | N/A | Impact of Foods on Bile Acids, Metabolites, and Inflammation | February 24, 2022 | May 2024 |
| NCT05464784 | Recruiting | Phase 2 | MN-001 in Non-alcoholic Fatty Liver Disease, Type 2 Diabetes Mellitus, and Hypertriglyceridemia | August 22, 2022 | December 31, 2024 |
| NCT03527069 | Recruiting | Phase 3 | Efficacy and Safety of Cipros 10 Association on the Isolated Hypertriglyceridemia and Dyslipidemia Treatment | January 29, 2021 | February 28, 2025 |
| NCT06347133 | Recruiting | Phase 3 | Phase 3 Study of Plozasiran in Adults With Hypertriglyceridemia | May 21, 2024 | October 2026 |
| NCT05743868 | Recruiting | N/A | Metabolic Heterogeneity Underlying Hypertriglyceridemia: Hepatic Triglyceride Biosynthesis in Humans With Different Insulin Resistance Phenotypes | November 16, 2023 | August 2024 |
| NCT01527747 | Suspended | Phase 4 | Effects of DPP-4 Inhibition on Triglycerides | January 2012 | December 2024 |
| NCT00329862 | Terminated | N/A | Laparoscopic Adjustable Gastric Banding With Truncal Vagotomy | May 2006 | May 2006 |
| NCT02036307 | Terminated | Phase 2 | Supplementation With Omega-3: Mechanism of Action | April 2013 | January 2015 |
| NCT04365400 | Terminated | Phase 2 | Assess Efficacy and Safety of Epeleuton in Patients With Hypertriglyceridemia and Type 2 Diabetes | October 13, 2020 | May 3, 2022 |
| NCT04419688 | Terminated | Phase 1 | A First in Human Study of STT-5058, an Antibody That Binds ApoC3 | May 26, 2020 | December 23, 2022 |
| NCT00672633 | Terminated | Phase 2 | Trial of Lovaza in Adolescents With Mild to Moderately Elevated Triglycerides | April 2008 | March 2012 |
| NCT00080132 | Terminated | Phase 2 | Implitapide in Patients With Hypertriglyceridemia (HTG) on Maximal, Concurrent Triglyceride-Lowering Therapy | October 2004 | April 2005 |
| NCT00691288 | Terminated | Phase 2 | Effect of Omega-3 Fatty Acid Supplementation on Hypertriglyceridemia in HIV-infected Children | June 2008 | December 2012 |
| NCT01474434 | Terminated | Phase 2 | Efficacy of LCQ908 on Cardiovascular Risk | December 2011 | June 2014 |
| NCT04863014 | Terminated | Phase 2 | Efficacy and Safety of Evinacumab in Adult Patients With Severe Hypertriglyceridemia for the Prevention of Recurrent Acute Pancreatitis | July 12, 2021 | February 15, 2023 |
| NCT00278928 | Terminated | N/A | Fat Tolerance From Lipid Emulsion Infusion Packaged in Glass or Plastic | January 2006 | April 2007 |
| NCT01096446 | Terminated | N/A | Intravenous Fat Emulsions and Premature Infants | April 2008 | July 2010 |
| NCT00231621 | Terminated | Phase 3 | A Study on Efficacy and Safety of Topiramate in Treatment of Obese Subjects With Dyslipidemia | May 2001 | June 2002 |
| NCT02625870 | Unknown status | Phase 3 | Omega-3-Acid Ethyl Esters 90 Soft Capsules for Lowering Very High Triglycerides | December 2015 | |
| NCT00934219 | Unknown status | Phase 4 | Triglyceride Lowering Study | July 2009 | December 2012 |
| NCT01908374 | Unknown status | N/A | Bioavailability of EPA and DHA From Two Dietary Supplements | July 2013 | December 2013 |
| NCT03501680 | Unknown status | Phase 4 | Intensive Insulin for Severe/Moderate Hypertriglyceridemia Pancreatitis. | June 6, 2018 | December 31, 2020 |
| NCT02015988 | Unknown status | Phase 4 | Simvastatin and Fenofibrate vs Simvastatin Alone in Patients With Type 2 Diabetes Mellitus and Acute Coronary Syndrome | January 2014 | May 2017 |
| NCT03342807 | Unknown status | Phase 4 | Intravenous Administration of Insulin and Plasma Exchange on Triglyceride Levels in Early Stage of Hypertriglyceridemia-induced Pancreatitis | November 2017 | November 2020 |
| NCT04241081 | Unknown status | N/A | Interrupting Prolonged Sitting With Periodic Interval Exercise: Effect on Postprandial Lipemia | January 2020 | May 2020 |
| NCT00758927 | Unknown status | Phase 4 | The Effects of Omega-3 Fatty Acid (OMACOR) on the Low-density Lipoprotein (LDL) Sub-fraction in Type 2 Diabetic Patients | July 2009 | July 2010 |
| NCT01480687 | Unknown status | Phase 4 | Fish Oil Supplementation and Vascular Function in Hypertensive Patients With Hypertriglyceridemia | May 2011 | December 2012 |
| NCT03850405 | Unknown status | N/A | Dark Chocolate, Cholesterol and Microbiota | May 1, 2019 | March 1, 2020 |
| NCT04097990 | Unknown status | N/A | Characterization of Fatty Acid Composition of Triglycerides in Patients With Hypertriglyceridemia-induced Acute Pancreatitis | October 1, 2019 | October 30, 2020 |
| NCT00973271 | Withdrawn | Phase 3 | Diazoxide Choline Controlled-Release Tablet (DCCR) for Very High Triglycerides | March 2011 | December 2011 |
| NCT00397358 | Withdrawn | Phase 4 | Effect of Extraneal (Icodextrin)on Triglyceride Levels in PD Patients | November 2006 | June 2007 |
| NCT00029250 | Withdrawn | Phase 2 | Garlic in Hyperlipidemia Caused by HAART | November 2001 | May 2003 |
| NCT01180764 | Withdrawn | Phase 4 | Effects of Lovaza on High Density Lipoprotein (HDL) Composition and Function in Hypertriglyceridemia | August 2010 | October 2012 |
| NCT00901823 | Withdrawn | Phase 1 | Open-Label, Single- and Multiple-Dose Pharmacokinetic Study of Diazoxide Choline | March 2011 | March 2011 |
- HPO alt_id (Human Phenotype Ontology)
- HP:0003082
- HPO alt_id (Human Phenotype Ontology)
- HP:0008174
- HPO alt_id (Human Phenotype Ontology)
- HP:0008332
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0002155
- MeSH unique ID (MeSH (Medical Subject Headings))
- D015228