Hyperkalemia
Information
- Disease name
- Hyperkalemia
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05408039 | Active, not recruiting | Tracking Treatment Pathways in Adult Patients With Hyperkalemia. | July 14, 2022 | December 16, 2024 | |
| NCT04864795 | Active, not recruiting | Cardiovascular and Renal Treatment in Heart Failure Patients With Hyperkalaemia or at High Risk of Hyperkalaemia | April 19, 2021 | August 2024 | |
| NCT05297409 | Active, not recruiting | An Observational Prospective Cohort Study for Long-term Management of Hyperkalemia in Patients With Chronic Kidney Disease or Heart Failure | May 21, 2022 | August 8, 2025 | |
| NCT01349218 | Completed | N/A | Relationship Between Potassium Level in Venous Blood Samples Drawn and Heel Sticks In Infants and Newborns | March 2014 | March 2014 |
| NCT01371747 | Completed | Phase 2 | Patiromer in the Treatment of Hyperkalemia in Patients With Hypertension and Diabetic Nephropathy (AMETHYST-DN) | June 2011 | June 2013 |
| NCT01493024 | Completed | Phase 2 | Safety & Efficacy of Zirconium Silicate in Chronic Kidney Disease or Moderate Kidney Dysfunction With Mild Hyperkalemia | November 30, 2011 | June 30, 2012 |
| NCT01737697 | Completed | Phase 3 | Safety & Efficacy of Zirconium Silicate in Mild to Moderate Hyperkalemia | November 30, 2012 | November 30, 2013 |
| NCT06281470 | Completed | Phase 1 | The Safety and Tolerability of WS016 in Healthy Chinese Volunteers | February 13, 2023 | June 15, 2023 |
| NCT02020317 | Completed | N/A | Clinical Decision Support System for Quality Assurance in Potassium-Increasing Drug-Drug-Interactions | January 2014 | January 2015 |
| NCT05860491 | Completed | Dietary Fiber and Hyperkalemia in Dialysis Patients | January 1, 2022 | June 30, 2022 | |
| NCT02065076 | Completed | Phase 4 | Efficacy of Sodium Polystyrene Sulfonate in the Treatment of Hyperkaliemia in Pre-dialysis Patients | February 2014 | October 2014 |
| NCT02088073 | Completed | Phase 3 | Safety & Efficacy of Zirconium Silicate Dosed for 28 Days in Hyperkalemia. | March 31, 2014 | January 31, 2015 |
| NCT02107092 | Completed | Phase 3 | Open-label Safety & Efficacy of ZS (Sodium Zirconium Cyclosilicate)10g qd to Extend Study ZS-004 in Hyperkalemia. | May 31, 2014 | August 31, 2015 |
| NCT02163499 | Completed | Phase 3 | Open-label Safety and Efficacy of Sodium Zirconium Cyclosilicate for up to 12 Months | June 30, 2014 | November 30, 2016 |
| NCT02483702 | Completed | N/A | Irradiated Blood Versus Non Irradiated Blood Transfusions in Craniosynostosis Repair | August 2015 | May 11, 2017 |
| NCT02607085 | Completed | REal World EVidence for TrEAtment of HyperkaLemia in Emergency Department: Multicenter, Prospective, Observational Study | October 31, 2015 | May 31, 2016 | |
| NCT02609841 | Completed | POtassium and Cardiac Rhythm Trends in MaintENance HemoDialysis: A Multicenter, Prospective, Observational Study | September 30, 2015 | May 31, 2016 | |
| NCT02694744 | Completed | Phase 4 | Patiromer With or Without Food for the Treatment of Hyperkalemia | February 2016 | August 2016 |
| NCT02825784 | Completed | N/A | A Multicenter Study to Evaluate the Nutritional Suitability of Renastart | January 6, 2017 | October 31, 2019 |
| NCT02875834 | Completed | Phase 3 | A Study to Investigate the Safety and Efficacy of ZS in Patients With Hyperkalemia | March 3, 2017 | February 14, 2018 |
| NCT05535920 | Completed | Phase 4 | A Prospective, Randomized, Open-Label, Cross-Over Study of Lokelma to Control Interdialytic Hyperkalemia | April 14, 2022 | April 1, 2024 |
| NCT03071263 | Completed | Phase 2 | Spironolactone With Patiromer in the Treatment of Resistant Hypertension in Chronic Kidney Disease | January 23, 2017 | November 27, 2018 |
| NCT05441852 | Completed | A Study to Detect Hyperkalemia Using Smartphone-enabled Electrocardiogram (EKG) | March 31, 2022 | July 7, 2023 | |
| NCT03127644 | Completed | Phase 2/Phase 3 | ZS Ph2/3 Dose-response Study in Japan | June 14, 2017 | February 23, 2018 |
| NCT03161977 | Completed | The Effect of Mannitol on the Serum Potassium During Craniotomy | January 1, 2017 | June 1, 2017 | |
| NCT03172702 | Completed | Phase 3 | Open-label Safety of Sodium Zirconium Cyclosilicate for up to 12 Months in Japanese Subjects With Hyperkalemia | September 4, 2017 | July 6, 2019 |
| NCT03183778 | Completed | Phase 4 | Use of Patiromer to Transition Chronic Kidney Disease Patients With Hyperkalemia to a Plant-rich Diet. | March 12, 2018 | August 1, 2019 |
| NCT03229265 | Completed | Phase 4 | Pharmacokinetic Study of Tacrolimus and Mycophenolate Mofetil in Kidney Transplant Recipients With Hyperkalemia Receiving Patiromer | August 1, 2017 | August 7, 2019 |
| NCT05382988 | Completed | Phase 3 | Sodium Zirconium Cyclosilicate Lowers Hyperkalemia After Parathyroidectomy | November 2016 | December 2021 |
| NCT03283267 | Completed | Phase 1 | A Safety and Pharmacodynamic Study of Healthy Chinese Subjects Administered Sodium Zirconium Cyclosilicate (ZS) | October 24, 2017 | November 23, 2017 |
| NCT03303521 | Completed | Phase 3 | A Study to Test Whether ZS (Sodium Zirconium Cyclosilicate) Can Reduce the Incidence of Increased Blood Potassium Levels Among Dialized Patients. | December 14, 2017 | November 7, 2018 |
| NCT03326583 | Completed | Phase 2 | The Effects of Patiromer on Serum Potassium Level and Gut Microbiome of ESRD Patients With Hyperkalemia | November 1, 2017 | December 31, 2020 |
| NCT03337477 | Completed | Phase 2 | A Study to Evaluate a Potassium Normalization Treatment Regimen Including Sodium Zirconium Cyclosilicate (ZS) Among Patients With S-K ≥5.8 | February 13, 2018 | December 21, 2018 |
| NCT03528681 | Completed | Phase 3 | A Study to Investigate the Safety and Efficacy of ZS in Patients With Hyperkalemia. | May 6, 2021 | September 15, 2022 |
| NCT03781089 | Completed | Phase 4 | Patiromer Efficacy to Reduce Episodic Hyperkalemia in End Stage Renal Disease Patients | June 20, 2019 | March 15, 2023 |
| NCT03799926 | Completed | Phase 2 | Exploratory Study of ZG-801 for the Treatment of Hyperkalemia | February 18, 2019 | February 2, 2021 |
| NCT05184998 | Completed | Description of the Clinical Outcomes of Hospitalized Patients With Heart Failure With Different Serum Potassium Levels | November 30, 2021 | July 13, 2022 | |
| NCT03888066 | Completed | Phase 3 | Patiromer for the Management of Hyperkalemia in Subjects Receiving RAASi Medications for the Treatment of Heart Failure (DIAMOND) | April 24, 2019 | September 2, 2021 |
| NCT05118022 | Completed | N/A | Artificial Intelligence Identified Dyskalemia Using Electrocardiogram (AIDE) | January 1, 2022 | February 28, 2023 |
| NCT04141800 | Completed | Spanish Study of Hyperkalaemia Incidence and Prognosis in Patients With Heart Failure and Reduced Ejection Fraction | April 30, 2019 | March 31, 2021 | |
| NCT04207203 | Completed | N/A | Healthy Diet Rich in Potassium to Chronic Kidney Disease With Sodium Zirconium Cyclosilicate: A Feasibility Study | November 3, 2020 | May 10, 2023 |
| NCT04217590 | Completed | Phase 3 | Reduce Incidence of Pre-Dialysis Hyperkalaemia With Sodium Zirconium Cyclosilicate in Chinese Subjects | November 16, 2020 | January 3, 2022 |
| NCT04251468 | Completed | N/A | Clinical Potassium Pilot Study | April 29, 2020 | September 9, 2020 |
| NCT04256369 | Completed | Rate of Termination of Premixed Parenteral Nutrition (PN) in Surgical Patients Secondary to High Serum Electrolytes | February 2, 2020 | December 30, 2021 | |
| NCT05029310 | Completed | Phase 4 | Effects of Patiromer on Pharmacokinetics of Immunosuppresive Drugs in Renal Transplant Recipients | September 1, 2021 | February 1, 2023 |
| NCT04466969 | Completed | Assessment of Hyperkalemia's Illness and Treatment Burden in Chronic Kidney Disease and Heart Failure Patients: HK Registry Pilot Study | July 31, 2020 | November 30, 2020 | |
| NCT04955678 | Completed | Phase 3 | A Comparative Study of ZG-801 and Placebo in Patients With Hyperkalemia | August 3, 2021 | March 13, 2023 |
| NCT04799067 | Completed | Hyperkalaemia Prevalence, Recurrence and Treatment in Haemodialysis | May 17, 2021 | July 18, 2022 | |
| NCT04780841 | Completed | Phase 2 | A Study Evaluating the Safety and Efficacy of RDX013 for the Treatment of Hyperkalemia | January 11, 2021 | March 3, 2022 |
| NCT00290160 | Completed | N/A | Early Protein Supplementation on Prevention of Hyperkalemia | December 2002 | July 2007 |
| NCT00868439 | Completed | Phase 2 | Evaluation of Patiromer in Heart Failure Patients | April 2009 | December 2009 |
| NCT06366230 | Not yet recruiting | Phase 1/Phase 2 | Adding Urea to the Final Dialysis Fluid | July 1, 2024 | June 30, 2028 |
| NCT06365684 | Not yet recruiting | Phase 4 | Sodium Zirconium Cyclosilicate to Allow Liberal Fruit and Vegetable Intake for Patients With CKD Stage 3b and 4 | April 29, 2024 | May 1, 2025 |
| NCT04789239 | Recruiting | Phase 2 | OPtimizing Aldosterone Receptor Antagonist Therapy by Sodium Zirconium Cyclosilicate in Heart Failure | September 1, 2021 | December 30, 2024 |
| NCT04510792 | Recruiting | IMpact of hyPeRkalaemia on thErapy With Renin angiotenSin aldoSterone System Inhibitors | July 12, 2021 | August 12, 2024 | |
| NCT05004363 | Recruiting | Phase 3 | Lokelma for RAAS Maximisation in CKD & Heart Failure. | January 19, 2022 | December 31, 2023 |
| NCT05090865 | Recruiting | N/A | Dietary Potassium Liberalization in Pre-Dialysis Patients | January 15, 2024 | October 31, 2025 |
| NCT04012138 | Recruiting | Phase 4 | Insulin Dextrose Infusion vs Nebulized Salbutamol vs Combination of Salbutamol and Insulin Dextrose in Acute Hyperkalemia | December 20, 2019 | June 20, 2026 |
| NCT05136664 | Recruiting | Phase 3 | Trial Evaluating the Efficacy and Safety of Patiromer in Chinese Subjects | February 10, 2022 | November 2026 |
| NCT03253172 | Recruiting | N/A | Potassium Supplementation in CKD | July 1, 2017 | October 1, 2025 |
| NCT05766839 | Recruiting | Phase 2 | Patiromer for Treatment of Hyperkalaemia in Children Under 12 Years of Age | September 2024 | August 2028 |
| NCT05786469 | Recruiting | Phase 3 | Patiromer Trial in CKD Stage IIIB to V | August 2, 2023 | June 2025 |
| NCT06029179 | Recruiting | N/A | SZC Versus SPS for Treatment of Hyperkalemia in Hemodialysis Patients | January 15, 2024 | June 15, 2024 |
| NCT06036823 | Recruiting | Phase 4 | 5 Versus 10 Units of Insulin in Hyperkalemia Management | October 1, 2023 | December 2024 |
| NCT06256991 | Recruiting | Phase 4 | Potassium Correction for RAAS Optimization in Chronic Kidney Disease | April 1, 2024 | December 2026 |
| NCT06277128 | Recruiting | Phase 2 | A Study to Evaluate the Safety and Efficacy of WS016 in Patients With Hyperkalemia. | September 11, 2023 | August 4, 2024 |
| NCT03597035 | Terminated | Phase 4 | Mineralocorticoid Receptor Antagonism Clinical Evaluation in Atherosclerosis Add-On | July 17, 2018 | July 31, 2020 |
| NCT04847232 | Terminated | Phase 3 | Effect of Sodium Zirconium Cyclosilicate on Arrythmia-related Cardiovascular Outcomes in Participants on Chronic Hemodialysis With Recurrent Hyperkalemia (DIALIZE-Outcomes) | April 30, 2021 | March 7, 2024 |
| NCT04983979 | Terminated | Phase 2 | The ORTIZ Study: Optimising RASi Therapy With SZC | June 17, 2022 | May 16, 2023 |
| NCT03018067 | Terminated | Phase 2 | A Study Evaluating the Onset-of-Action, Safety, and Efficacy of RDX227675 for the Treatment of Hyperkalemia | January 2017 | May 2017 |
| NCT04443608 | Terminated | Phase 4 | Patiromer Utility as an Adjunct Treatment in Patients Needing Urgent Hyperkalemia Management | October 8, 2020 | June 3, 2023 |
| NCT05056727 | Terminated | Phase 3 | A Study to Evaluate the Effect of Sodium Zirconium Cyclosilicate on Chronic Kidney Disease (CKD) Progression in Participants With CKD and Hyperkalaemia or at Risk of Hyperkalaemia | September 30, 2021 | February 7, 2024 |
| NCT01866709 | Terminated | Phase 4 | Safety and Efficacy of Sodium Polystyrene Sulfonate in Hyperkalemia | May 2013 | August 2013 |
| NCT02033317 | Terminated | Phase 2 | An Open-Label, Multiple Dose Study to Evaluate the Pharmacology, Safety, and Tolerability of Patiromer in Participants on Hemodialysis | August 2008 | December 2008 |
| NCT03087058 | Terminated | Phase 2 | Pharmacodynamic & Safety of Patiromer in Children & Adolescents (2-<18 Yrs) With Chronic Kidney Disease and Hyperkalemia | July 7, 2017 | April 30, 2021 |
| NCT03096561 | Unknown status | N/A | Measurement of Serum Potassium Rate During Accidental Hypothermia. | November 14, 2016 | July 2019 |
| NCT04727840 | Unknown status | Phase 1 | Potassium Binder in CKD Patients (With Hyperkalemia) (DiPo Trial) | March 15, 2021 | January 15, 2022 |
| NCT03833089 | Unknown status | Phase 4 | Targeted Potassium Levels for Prevention of ICD Therapy | April 1, 2019 | February 5, 2024 |
| NCT05086185 | Unknown status | Effect of Viscous Fiber on Postprandial Kalemic Response in Hemodialysis Patients | June 29, 2021 | June 30, 2022 | |
| NCT05173584 | Unknown status | Phase 4 | Levalbuterol Compared to Albuterol Regarding Cardiac Side Effects and Potassium Lowering Effects. | November 4, 2021 | December 31, 2021 |
| NCT00162487 | Unknown status | N/A | Genetic Determinants of the Hypokalemic and Hyperglycemic Effect of Albuterol Inhalation | August 2002 |
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0002153
- MeSH unique ID (MeSH (Medical Subject Headings))
- D006947