opioid use

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Disease name
opioid use
Disease ID
Description
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Chromosome band
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Annotation
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NCT ID Status Phase Summary Start date Completion date
NCT04885231 Active, not recruiting N/A Impact of Counseling and Education on Opioid Consumption After ACL Reconstruction May 12, 2021 March 31, 2025
NCT04263909 Active, not recruiting Phase 4 The Impact of Sublingual Sufentanil on Postoperative Pain and Analgesic Requirements in Spine Surgery Patients December 1, 2020 December 30, 2022
NCT04838925 Active, not recruiting N/A Using Mobile Devices for Neurofeedback to Reduce Opioid Use in Chronic Pain June 22, 2022 April 2024
NCT05571072 Active, not recruiting N/A Opioid Use After Urogynecologic Procedures: Using a Predictive Calculator January 2, 2023 June 1, 2024
NCT04617938 Active, not recruiting N/A TACUNA (Traditions and Connections for Urban Native Americans) November 23, 2020 August 30, 2024
NCT05548582 Active, not recruiting N/A Reduced Opioid Prescription After Laparoscopic Hysterectomy January 12, 2023 December 31, 2024
NCT04550715 Active, not recruiting N/A Prevention Interventions for Opioid Misuse January 4, 2021 March 30, 2025
NCT03485430 Active, not recruiting N/A Tapering From Long-term Opioid Therapy in Chronic Pain Population. Randomized Controlled Trial With 12 Months Follow up March 22, 2018 December 30, 2025
NCT03498261 Active, not recruiting Phase 1 A Prospective Randomized Double Blind Trial to Assess the Effect of a Single Preoperative Dose of Gabapentin on Postoperative Opioid Consumption in Patients Undergoing Rhinoplasty January 30, 2018 December 30, 2024
NCT05280743 Active, not recruiting Precision Opioid Care After Cesarean Delivery (PRECISE-CD) March 28, 2022 June 1, 2024
NCT05226026 Active, not recruiting N/A NiteCAPP_HELPS_WD: Improving Sleep and Reducing Opioid Use in Chronic Pain Patients March 31, 2022 December 15, 2024
NCT05203770 Active, not recruiting Adaptations of the Brain in Chronic Pain With Opioid Exposure I October 31, 2018 June 30, 2024
NCT04648774 Active, not recruiting N/A Continuous Serratus Anterior Blockade for Sternotomy July 22, 2021 August 2023
NCT04247646 Active, not recruiting N/A SLeep and OPioid UsE in Patients Undergoing Total Knee Arthroplasty October 1, 2020 December 31, 2028
NCT04494698 Active, not recruiting N/A Impact of DuoTherm on Opioid Use and Chronic Low Back Pain June 23, 2022 July 29, 2024
NCT04491175 Active, not recruiting N/A Impact of DuoTherm on Acute Opioid Use and Low Back Pain June 23, 2022 July 29, 2024
NCT04216719 Active, not recruiting N/A Facilitating Opioid Care Connections March 18, 2020 December 1, 2025
NCT04122196 Active, not recruiting Phase 2/Phase 3 Perioperative Pregabalin in Ureteroscopy June 1, 2020 July 1, 2024
NCT03843788 Active, not recruiting N/A TENS and Opioid Use After Cesarean Delivery November 9, 2018 December 2022
NCT03834792 Active, not recruiting Adverse Long-term Consequences of Sleep Disordered Breathing: The Ottawa Hospital (TOH) Sleep Database December 30, 2018 December 2028
NCT05197465 Active, not recruiting Persistent Opioid Consumption After Major Abdominal Surgery and Its Determinants February 13, 2022 September 30, 2024
NCT04452344 Active, not recruiting Phase 3 Opioid Analgesic Reduction Study January 4, 2021 December 31, 2025
NCT06167759 Active, not recruiting N/A Preventing Opioid Misuse Through Safe Opioid Use Agreements Between Patients and Surgical Providers December 5, 2022 April 30, 2024
NCT04394559 Active, not recruiting N/A Prevention of Opioid Use Disorder After Surgery July 2, 2021 January 1, 2024
NCT03781440 Active, not recruiting N/A Regional Anesthesia for Cardiothoracic Enhanced Recovery January 1, 2020 December 2023
NCT03372382 Completed Phase 4 Ibuprofen and Acetaminophen Versus Ibuprofen and Acetaminophen Plus Hydrocodone for Analgesia After Cesarean Section December 13, 2017 April 10, 2018
NCT03377855 Completed N/A Addressing Origins of the Opioid Epidemic by Improving Prescribing for Opioid-Naive Patients February 1, 2018 December 31, 2019
NCT03380949 Completed N/A Monitor-Guided Analgesia During General Anesthesia - Part II December 8, 2017 June 7, 2018
NCT03411759 Completed Cytochrome P450's Pharmacogenomics in Chronic Pain Patients January 8, 2018 March 23, 2018
NCT03417193 Completed N/A Opioid Free Anesthesia and Major Spine Surgery January 29, 2018 February 16, 2023
NCT03422211 Completed A Prospective Assessment of Opioid Utilization Post-operatively in Sports Orthopaedic Surgeries November 16, 2017 November 2, 2018
NCT03450161 Completed Phase 4 Hyperalgesia, Persistent Pain, and Fentanyl Dosing in On-Pump Coronary Artery Bypass Grafting May 14, 2018 January 9, 2021
NCT03457116 Completed Phase 4 Narcotics vs NSAIDs for Post-operative Analgesia in Outpatient Rhinoplasty January 30, 2018 November 2, 2020
NCT03458598 Completed N/A Pre-Operative Single Shot Rectus Sheath Block February 16, 2018 February 5, 2019
NCT03467230 Completed Performance Assessment of the PMD-200 Under General Anesthesia March 15, 2018 December 12, 2018
NCT03472521 Completed Phase 4 Prevention of Persistent Opioid Use in Mothers September 17, 2018 April 10, 2021
NCT03507634 Completed N/A Opioid Free Anesthesia in Bariatric Surgery April 11, 2018 June 30, 2020
NCT03508830 Completed Phase 3 Minimally Invasive Thoracic Surgery Intercostal Nerve Block Trial December 30, 2018 January 30, 2021
NCT03525275 Completed N/A Effect of Battlefield Acupuncture and Physical Therapy Versus Physical Therapy Alone After Shoulder Surgery August 15, 2018 April 15, 2019
NCT03532256 Completed Post-op Crowd Sourcing Health Data Via Text-messaging October 1, 2018 November 5, 2023
NCT03536065 Completed N/A Post-Discharge Opioid Reduction Intervention for Open, Laparoscopic, and Endoscopic Surgery August 1, 2017 March 1, 2019
NCT03540030 Completed Phase 4 Opioid-Free Shoulder Arthroplasty September 2016 June 2019
NCT03565705 Completed Spinal Anesthesia and Peri-operative Opioid Consumption in Open Abdominal Prostatectomy April 24, 2018 October 14, 2018
NCT03568396 Completed Validation of Pupillary Response to Nociceptive Stimulation in Cardiac Surgery During Extracorporeal Circulation Period August 22, 2018 October 25, 2018
NCT03570320 Completed N/A Does Altering Narcotic Prescription Methods Affect Opioid Distribution Following Select Upper Extremity Surgeries? September 4, 2018 February 29, 2020
NCT03576781 Completed Early Phase 1 Developing rTMS Treatment Strategies for Pain in Opiate Dependence February 9, 2017 November 12, 2019
NCT03836235 Completed Development of a Risk Prediction Screening Tool for Opioid-Prescription Injury (STOP Injury) in Older Adults Initiated on Opioids From the Emergency Department March 4, 2019 April 3, 2020
NCT00781131 Completed Phase 4 Trial of Pregabalin for Post-operative Pain in Women Undergoing Abdominal Hysterectomy May 2008 January 2011
NCT02509312 Completed Phase 4 Prospective Effect of Intravenous Ketorolac on Opioid Use, EBL and Complications Following Cesarean Delivery May 2016 October 2017
NCT03020966 Completed Phase 4 IV vs. Oral Acetaminophen as a Component of Multimodal Analgesia After Total Hip Arthroplasty February 16, 2017 June 16, 2019
NCT03030742 Completed Postpartum Opioid Prescribing Patterns and Patient Utilization June 1, 2017 December 31, 2019
NCT03034278 Completed Self-reported Usage Patterns of Opioid Analgesic Medications After Surgery February 3, 2017 July 31, 2021
NCT03044522 Completed N/A Use of a Nurse Pain Educator for Patients With Chronic Pain November 14, 2016 November 21, 2017
NCT03044808 Completed Phase 4 Investigation of the Effect of Intravenous Lidocaine Infusion on Postoperative Pain Treatment and Bowel Function in Robotic Bowel Surgery February 2, 2016 April 19, 2017
NCT03143855 Completed Phase 1 Drug Interaction and Subjective Effects of Compounds for Opioid Use Disorder January 30, 2017 April 5, 2019
NCT03168425 Completed N/A Opioid Prescribing After Cesarean Delivery June 14, 2017 September 21, 2017
NCT03179566 Completed N/A Pain and Medication Use Following Surgery June 6, 2017 September 1, 2017
NCT03183882 Completed N/A Peer Comparison Feedback on Opioid Prescribing August 7, 2017 September 28, 2017
NCT03234439 Completed N/A Digital Tools for Coping With Chronic Pain December 8, 2017 December 31, 2018
NCT03268551 Completed MEMO-Medical Marijuana and Opioids Study September 4, 2018 July 14, 2023
NCT03287622 Completed N/A Evaluation of an Interactive Opioid Risk Education Program (STOMP) for Parents October 24, 2017 September 30, 2019
NCT03295097 Completed N/A Characteristics and Clinical Implications of a Clinical Decision Support System March 8, 2018 January 21, 2020
NCT03303209 Completed Patient-Centered Opioid Tapering Study September 15, 2015 August 10, 2017
NCT03303651 Completed N/A Monitor-Guided Analgesia During General Anesthesia - Part I October 16, 2017 January 26, 2018
NCT03306147 Completed N/A Negating Opioid and Pain Actively Through Intervention October 12, 2017 May 17, 2018
NCT03314792 Completed Phase 4 Effects of Tapentadol Versus Oxycodone After Hysterectomy. December 4, 2017 February 28, 2019
NCT03319277 Completed N/A A Randomized-controlled Trial of Post-operative Opiate Quantities After Urogynecologic Surgery October 13, 2017 June 25, 2019
NCT03328208 Completed N/A Nonpharmacologic Reduction of Periprocedural Distress and Drug Use November 22, 2017 December 31, 2018
NCT03334903 Completed Phase 4 Gabapentin Regimens and Their Effects on Opioid Consumption May 15, 2018 April 24, 2019
NCT03355248 Completed N/A Satisfaction Following Cesarean Section August 18, 2017 August 14, 2020
NCT03365817 Completed Phase 3 Cognitive Function and Addiction Under Opioid Tapering February 2, 2009 December 1, 2014
NCT03593642 Completed N/A ESP Catheter Vs Single Shot ESP for Open Heart Surgery in Infants October 1, 2018 June 30, 2019
NCT03599427 Completed Phase 4 Added Value of Systemic Lidocaine on Postoperative Pain, Opiate Use and Nausea After Knee Arthroscopy September 1, 2018 June 30, 2019
NCT03611374 Completed N/A Regional Anesthesia for Cardiothoracic Enhanced Recovery (RACER) Study June 7, 2019 April 6, 2023
NCT03627897 Completed Phase 4 ESP Block in Pediatric Patients for Postoperative Analgesia August 1, 2019 April 1, 2021
NCT03628846 Completed Opioid Use After Traumatic Injury in Adolescents July 1, 2018 April 30, 2023
NCT03629197 Completed N/A Improving Communication About Pain and Opioids October 31, 2017 August 31, 2020
NCT03629314 Completed N/A Improving Surgical Patient Knowledge and Safe Use of Opioids August 15, 2018 September 30, 2020
NCT03666455 Completed N/A Treating Pain With Acceptance and Commitment Therapy Trial January 1, 2019 March 23, 2020
NCT03678870 Completed N/A Discharge Opioid Education to Decrease Opioid Use After Cesarean September 1, 2018 November 1, 2019
NCT03684681 Completed N/A The Navigator Trial November 14, 2018 November 30, 2022
NCT03705559 Completed Phase 1 Opioid and Cannabinoid Interactions June 21, 2019 February 15, 2024
NCT03717402 Completed N/A Smartphone Technology to Alleviate Malignant Pain (STAMP) November 1, 2018 May 1, 2022
NCT03726268 Completed Phase 4 Optimizing Outpatient Anesthesia (OSPREy-Outpatient Surgery Pain Relief Enhancement) November 29, 2018 January 30, 2024
NCT03726476 Completed N/A Expectations and Pain Control Advancement In surgeRy: The REPAIR Trial September 10, 2019 December 6, 2021
NCT03743493 Completed PCORnet Opioid Surveillance Study July 1, 2018 November 15, 2019
NCT03744065 Completed N/A Lumbar Plexus and Suprainguinal Fascia Iliaca Blocks For Total Hip Replacement November 19, 2018 January 23, 2020
NCT03747341 Completed Phase 1 Buprenorphine-Fentanyl Interaction Study March 22, 2018 January 4, 2019
NCT03763734 Completed Phase 4 High-Dose Steroid for Knee Arthroplasty Patients Expected to Have Postoperative Pain January 29, 2019 January 1, 2021
NCT03763760 Completed Phase 4 High-Dose Steroid for Hip Arthroplasty Patients Expected to Have Postoperative Pain January 29, 2019 January 1, 2021
NCT03782506 Completed N/A Pain Management Support Study for Cancer Survivors November 1, 2018 December 31, 2021
NCT03783702 Completed Phase 4 Pain Control Following Sinus Surgery April 4, 2019 December 30, 2020
NCT03791645 Completed N/A Evaluating The Efficacy Of A Mind-Body Intervention In Overcoming Opioid Addiction October 27, 2018 March 31, 2022
NCT03805386 Completed Phase 2/Phase 3 Patient-Directed Postoperative Opioid Prescribing for Gynecologic Surgery January 15, 2019 April 15, 2020
NCT03808025 Completed N/A Opioid Use in Shoulder Arthroplasty Patients: A Stratification and Algorithm January 21, 2019 May 4, 2023
NCT03809949 Completed Phase 4 Opioid Free Versus Opioid Balanced Anesthesia January 16, 2019 May 22, 2019
NCT03821103 Completed N/A Incentivizing Buprenorphine-Naloxone Initiation in Emergency Departments February 6, 2019 February 29, 2020
NCT03833648 Completed N/A UControlPain App (This is the Official IRB Title) June 19, 2019 April 20, 2020
NCT00221338 Completed Phase 3 Clinical Trial of Gabapentin to Decrease Postoperative Delirium and Pain January 2006 July 2014
NCT03855241 Completed N/A Safely Disposing of Surplus Prescription Opioids June 5, 2019 August 14, 2019
NCT03858621 Completed N/A Comparison of Postoperative Nociception Between NOL-guided and Standard Intraoperative Analgesia Based on Fentanyl March 15, 2019 February 23, 2022
NCT03863353 Completed N/A Scenario Tailored Opioid Messaging Program (STOMP) to Improve Risk Understanding in Young Adults November 1, 2019 December 1, 2021
NCT03889418 Completed N/A Opioid Treatment and Recovery Through a Safe Pain Management Program April 1, 2019 June 30, 2023
NCT03894501 Completed N/A Pilot of Mindfulness Oriented Recovery Enhancement in MethadoneTreatment January 31, 2019 June 19, 2019
NCT03912740 Completed N/A Effect of Dexmedetomidine on Nol-Index Guided Remifentanil Analgesia April 11, 2019 December 31, 2019
NCT03929640 Completed Phase 3 Management Of Pain After Cesarean Trial August 5, 2019 September 30, 2023
NCT03932799 Completed Comparing State Payer Strategies to Prevent Unsafe Opioid Prescribing August 6, 2019 June 30, 2022
NCT03934411 Completed N/A Effect of Increased Pain Tolerance on Exercise Performance March 1, 2018 March 7, 2019
NCT03957798 Completed N/A Evaluation of a Motion-Activated Refusal-Skills Training Video Game for Prevention of Substance Use Disorder Relapse February 5, 2016 October 31, 2016
NCT03959787 Completed N/A Surgical Patient Knowledge and Safe Use of Opioids May 23, 2019 September 30, 2020
NCT03961152 Completed N/A Effect of the PainCoach App on Pain and Opiate Use After Total Knee Replacement January 15, 2016 June 8, 2017
NCT03986866 Completed N/A Video-based, Patient-Focused Opioid Education in the Perioperative Period April 29, 2019 April 1, 2020
NCT03991546 Completed N/A Pain and Narcotic Usage After Orthopaedic Surgery June 3, 2016 June 17, 2019
NCT03999450 Completed N/A Preventing Premature Death in Patients With Serious Opioid-related Infection October 8, 2019 May 31, 2020
NCT04005599 Completed N/A Opioid Sparing General Venous Anesthesia With Magnesium Sulfate June 3, 2019 January 6, 2022
NCT04010266 Completed N/A RelieVRx for Total Knee Arthroplasty (TKA) for the Reduction of Acute Postoperative Pain and Opioid Use March 1, 2021 August 31, 2023
NCT04011176 Completed N/A Microcurrent Treatment for Chronic Debilitating Pain December 9, 2019 June 1, 2022
NCT04015908 Completed Phase 4 A Multimodal Analgesia Protocol Adapted for Ambulatory Surgery August 1, 2019 January 31, 2023
NCT04017013 Completed Phase 4 Therapeutic Efficacy of Intravenous Lidocaine Infusion Compared With Epidural Analgesia for Postoperative Pain Control in Adult Patients Undergoing Major Abdominal Surgery: Non-Inferiority Clinical Trial March 1, 2020 September 5, 2022
NCT04024397 Completed A Study to Evaluate Unintended Prolonged Opioid Use October 1, 2019 December 29, 2023
NCT04036968 Completed Phase 2 Enhancing Medication-based Analgesia in Humans- STUDY 2 February 1, 2020 November 1, 2022
NCT04037085 Completed Phase 2 Ketamine to Improve Recovery After Cesarean Delivery - Part 1 October 9, 2019 August 1, 2021
NCT04039191 Completed N/A SMS Education for Post-operative Pain December 9, 2019 July 30, 2023
NCT04043143 Completed N/A 24-hour Oral Morphine Equivalent Based Opioid Prescribing After Surgery October 24, 2019 January 13, 2021
NCT04044521 Completed N/A Promoting Clinical Guidelines for Opioid Prescribing January 31, 2020 September 1, 2022
NCT04049032 Completed Perinatal Opioid Use September 1, 2017 December 31, 2018
NCT04058938 Completed N/A Pain in Breast Surgery Intervention March 1, 2018 March 1, 2020
NCT04083209 Completed N/A Effect of Preoperative Counseling on Postoperative Opioid Use Following Knee Arthroscopy. October 15, 2019 June 26, 2020
NCT04084392 Completed N/A Evaluating the Impact of the Bridge Clinic in Patients With Opioid Use Disorder November 25, 2019 January 18, 2022
NCT04087317 Completed N/A Vaginal Postpartum Pain Management Protocol Comparison June 1, 2020 July 30, 2022
NCT04129086 Completed Phase 4 Ketamine for Acute Pain Management After Trauma July 1, 2020 September 30, 2022
NCT04134767 Completed N/A Kentucky Communities and Researchers Engaging to Halt the Opioid Epidemic (CARE2HOPE) November 15, 2019 October 27, 2022
NCT04154384 Completed N/A Life Care Specialists (LCS) With a Focus on Patient Pain Management and Prevention of Substance Misuse February 21, 2020 December 19, 2022
NCT04156581 Completed Phase 4 Erector Spinae Plane Block Versus Conventional Analgesia in Complex Spine Surgery November 19, 2019 June 18, 2022
NCT04156802 Completed N/A Project Relief: Developing Brain Stimulation as a Treatment for Chronic Pain June 15, 2020 July 6, 2022
NCT04157075 Completed Early Phase 1 Intra-operative Uterosacral Ligament Bupivacaine Injection During Minimally Invasive Hysterectomy March 15, 2021 October 15, 2022
NCT04175509 Completed Phase 4 Improving Post-Operative Pain and Recovery in Gynecologic Surgery December 23, 2019 June 1, 2021
NCT04184362 Completed N/A Empower Opioid Misuse & Chronic Pain November 20, 2019 March 21, 2022
NCT04197570 Completed Phase 3 Opioid-free Anesthesia for Open Cardiac Surgery: A Prospective Randomized Controlled Trial February 4, 2020 March 14, 2020
NCT04225468 Completed N/A Safe Options for ACL Recovery February 12, 2020 June 3, 2022
NCT04246541 Completed Phase 3 Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic Meniscus Surgery April 23, 2019 September 12, 2021
NCT04257695 Completed N/A Developing and Pilot Testing an Opioid Tapering Protocol May 4, 2021 August 31, 2023
NCT04260659 Completed Phase 4 Opioid Free vs Opioid Based Anesthesia for Laparoscopic Sleeve Gastrectomy February 4, 2020 February 22, 2023
NCT04277975 Completed N/A Liberal vs. Restricted Post-discharge Opioid Prescribing Following Midurethral Sling June 1, 2020 July 1, 2022
NCT04294550 Completed Study on Quality of Life in Advanced Cancer Patients With Opioid-induced Constipation Treated With Naloxegol September 1, 2018 March 31, 2021
NCT04296396 Completed Phase 3 Opioid Prescription After Cesarean Trial September 21, 2020 July 8, 2022
NCT04308148 Completed Does Medical Cannabis Reduce Opioid Use in Adults With Pain October 6, 2020 March 13, 2024
NCT04315181 Completed Phase 1 Prescription Medication Interactions March 25, 2019 May 6, 2023
NCT04374396 Completed N/A Erector Spinea Plane Block in Pediatric Hip Surgery July 28, 2020 February 2, 2021
NCT04396587 Completed Phase 4 Non-analgesic Effects Produced by Equipotent Analgesic Doses of Sufentanil, Hydromorphone, and Oxycodone May 20, 2020 June 1, 2023
NCT04419168 Completed N/A Cognitive Behavioral Therapy and Real-Time Pain Management Intervention for Sickle Cell Via Mobile Applications August 12, 2020 December 11, 2023
NCT04436926 Completed N/A Opioid Approach Bias Modification March 1, 2021 November 30, 2023
NCT04443569 Completed Phase 3 Lidocaine Patches After Cesarean Section October 10, 2021 August 31, 2022
NCT04446975 Completed N/A Best Practice Alert for Opioid Prescribing July 7, 2020 June 8, 2021
NCT04457115 Completed N/A Erector Spinae Plane Block Versus Thoracic Paravertebral Block for Pain Control in Modified Radical Mastectomy April 27, 2020 November 15, 2021
NCT04459234 Completed Prospective Multicentre Study of the Use of Ketamine in the Treatment of Refractory Chronic Pain in the French CLCC February 2, 2021 March 9, 2023
NCT04474366 Completed Phase 4 The Effect of Pectoral Blocks on Perioperative Pain in Gender Affirmation Top Surgery June 16, 2020 April 30, 2022
NCT04484610 Completed Phase 4 Appropriate Opioid Quantities for Acute Pain - Pharmacist Study September 8, 2020 March 31, 2022
NCT04491617 Completed N/A STandard Versus No Opioid Prescription After Prolapse and Anti-INcontinence Surgery Trial August 27, 2020 August 31, 2022
NCT04491968 Completed N/A Mindfulness Oriented Recovery Enhancement for Chronic Pain and Opioid Relapse August 13, 2020 June 8, 2022
NCT04495725 Completed N/A Do Discounted Vouchers for Medical Cannabis Reduce Opioid Use in Adults With Pain October 6, 2020 March 13, 2024
NCT04498559 Completed Patient Knowledge on Pain Management and Safe Opioid Use July 24, 2020 December 12, 2020
NCT04509115 Completed Variation in Opioid Prescribing and Use for Acute Pain in Diverse Populations September 11, 2020 November 30, 2023
NCT04521920 Completed N/A Providing Suboxone and PrEP Using Telemedicine November 9, 2020 August 30, 2021
NCT04523766 Completed N/A Comparing the Impact of Mindful Interoceptive Mapping and Mindful Breathing on Pain and Opioid Use June 29, 2021 September 18, 2023
NCT04526236 Completed Phase 4 Influence of Aging on Perioperative Methadone Dosing September 3, 2019 July 13, 2022
NCT04543227 Completed Opioid Laws and Pediatric Use September 10, 2020 November 16, 2023
NCT04556552 Completed Phase 3 Non-Invasive Vagal Nerve Stimulation in Opioid Use Disorders November 13, 2020 September 13, 2022
NCT04581642 Completed Nociception-Level (NOL) for the Assessment of Pain in Patient Unable to Self-Report November 1, 2020 November 30, 2021
NCT04601246 Completed Understanding the Postpartum Pain Experience in Women of Minority Race/Ethnicity December 1, 2020 December 30, 2021
NCT04601480 Completed N/A PRescribing INterventions for Chronic Pain Via the Electronic Health Record Study - Current Opioid-User Population August 26, 2020 October 1, 2021
NCT04601493 Completed N/A PRescribing INterventions for Chronic Pain Via the Electronic Health Record Study - Opioid-Naive Population August 26, 2020 October 1, 2021
NCT04610398 Completed Phase 3 Perioperative Dexamethasone Reduces Postoperative Pain and Nausea After Hip Arthroscopy March 11, 2021 June 30, 2023
NCT04622813 Completed Phase 3 Nonopioid Analgesics and Cholecystectomy April 8, 2021 October 19, 2022
NCT04625231 Completed N/A Shared Decision-Making Tool for Opioid Prescribing After Ambulatory Hand Surgery in Veterans November 9, 2018 May 30, 2022
NCT04625283 Completed Phase 4 The Impact of Perioperative Ketamine Infusion on Surgical Recovery April 12, 2021 February 1, 2024
NCT04625868 Completed N/A Effectiveness of a Preoperative Educational Video for Reducing Opioid Consumption After Hand Surgery May 29, 2020 March 1, 2021
NCT04628832 Completed N/A Nudging Providers to Curtail Dangerous Opioid Prescribing: A Trial to Investigate Mechanisms April 15, 2021 July 12, 2021
NCT04646148 Completed N/A Optimization and Multi-Site Feasibility of Yoga for Chronic Pain in People in YOGAMAT-II - Phase I March 1, 2021 November 1, 2021
NCT04648072 Completed N/A How Does the Addition of Adductor Canal Block to Local Infiltration Affect Recovery in Patients Undergoing Total Knee Arthroplasty? A Feasibility Study. November 4, 2020 December 1, 2021
NCT04648683 Completed N/A Postoperative Telehealth Mindfulness Intervention After Spine Surgery December 21, 2021 August 25, 2022
NCT04693416 Completed Phase 2 SMART Trial: Intrapersonal and Interpersonal Stigma Reduction March 8, 2021 August 30, 2021
NCT04696445 Completed Pharmacokinetics of Morphine and Oxycodone in Frail Elderly Undergoing Cardiac Surgery October 1, 2020 November 26, 2021
NCT04710069 Completed N/A Postoperative Opt-In Narcotic Treatment Study June 26, 2020 January 30, 2021
NCT04734080 Completed Phase 4 Dronabinol in Total Knee Arthroplasty (TKA) March 1, 2021 April 1, 2024
NCT04797559 Completed N/A SZMN Blocks for Pain Control in Pediatric Patients Undergoing T&A November 29, 2021 April 19, 2023
NCT04805229 Completed A Difference-In-Differences Analysis of New Persistent Opioid Use After Surgery January 1, 2013 December 31, 2019
NCT04824300 Completed N/A Efect of Erector Spina Plane Block on Mastectomy November 1, 2020 February 25, 2021
NCT04824833 Completed N/A Effects of US-guided SAPB During Breast Surgery March 1, 2021 September 30, 2021
NCT04854252 Completed N/A Inflammatory Response to Opioid Versus Opioid Free Anesthesia November 12, 2020 March 29, 2021
NCT04854395 Completed Phase 4 Femoral Triangle Block With Popliteal Plexus Block Versus Femoral Triangle Block Versus Adductor Canal Block for TKA April 9, 2021 June 26, 2023
NCT04871425 Completed Phase 4 Ketamine Versus Fentanyl for Surgical Abortions April 27, 2021 October 14, 2021
NCT04873401 Completed N/A Leveraging Social Networks to Increase COVID-19 Testing Uptake April 20, 2021 January 1, 2023
NCT04888897 Completed The Experiences of People Prescribed Opioid Pain Medicines October 19, 2021 December 1, 2022
NCT04889833 Completed N/A Effects of Hypnosis Therapy on Outcomes in Shoulder Replacement Therapy December 19, 2020 December 1, 2023
NCT04897841 Completed Phase 4 Obstetric Liposomal Bupivacaine Via Surgical Transversus Abdominis Plane Block for Post Cesarean Pain Control October 11, 2021 October 13, 2022
NCT04902547 Completed N/A Evaluation of a Patient-Centred, Multidisciplinary Opioid Tapering Program for Individuals With Chronic Non-Cancer Pain on Long Term Opioid Therapy May 1, 2021 January 5, 2024
NCT04906239 Completed N/A The Effect of Bilateral Erector Spina Plane Block on Postoperative Pain in Adult Cardiac Surgery. June 1, 2021 March 15, 2022
NCT04910165 Completed Phase 3 Exparel Use in Adductor Canal Block After Total Knee Arthroplasty June 1, 2020 October 15, 2021
NCT04918446 Completed N/A Technology-Assisted Prescription Opioid Safety Education March 29, 2018 February 13, 2019
NCT04938492 Completed N/A The Association Between Loneliness and Substance Use August 12, 2021 July 1, 2023
NCT04939727 Completed N/A Suicide Prediction and Prevention for People at Risk for Opioid Use Disorder: Supplement to COMPUTE 2.0 August 3, 2021 July 31, 2022
NCT04955444 Completed N/A Opioid Use After Thyroid and Parathyroid Surgeries June 14, 2021 December 31, 2021
NCT05063227 Completed Prediction of Postoperative Pain by Nociception Monitoring October 6, 2021 January 4, 2023
NCT05098795 Completed N/A FOREward Together: Training Peer Recovery Coaches to Promote Retention and Adherence to MOUD October 20, 2021 August 14, 2023
NCT05108935 Completed N/A Providing PrEP, Hepatitis C Treatment, and MOUD Through Telemedicine at Greensboro SSP February 17, 2022 March 30, 2023
NCT05169281 Completed N/A Distribution of Medication Disposal Packets - Acute Opioid Prescribing March 24, 2021 May 26, 2021
NCT05221866 Completed N/A Efficiency And Quality In Post-Surgical Pain Therapy After Discharge March 14, 2022 December 10, 2023
NCT05252858 Completed N/A A Pilot Study Investigating the nCAP Signal Relief Patch in Subjects Undergoing Primary Hip or Knee Replacement Surgery March 21, 2022 October 8, 2022
NCT05262569 Completed Postoperative Opioid Use and Ileus Occurrence---A Case Control Study April 1, 2022 June 30, 2022
NCT05263635 Completed N/A Music Therapy in the Treatment of Perioperative Anxiety and Pain May 5, 2022 August 21, 2023
NCT05314335 Completed N/A Reflexology Socks and Opioid-induced Constipation October 30, 2020 July 7, 2022
NCT05321576 Completed N/A Opioid-free Anesthesia With ESPB in VATS Operation March 10, 2022 May 1, 2022
NCT05340855 Completed N/A A Pilot Study Using Facebook to Support Opioid Recovery Among American Indian Women May 5, 2022 June 8, 2023
NCT05358158 Completed N/A Chest dRain rEmoval intrAoperatively afTer thoracOscopic Wedge Resection May 4, 2022 March 17, 2024
NCT05358522 Completed N/A Increasing Implementation of Post-Operative Opioid Prescribing Guidelines June 1, 2022 November 5, 2023
NCT05375916 Completed N/A Comparison of Short-term Sustained-release Opioid in Open Abdominal Urologic Surgeries May 3, 2022 November 30, 2023
NCT05386069 Completed Phase 3 Does a Non-Opioid Multimodal Pain (NOMO) Protocol Decrease Narcotic Use November 15, 2019 June 1, 2021
NCT05393414 Completed N/A Efficacy of NSAID and Acetaminophen in the Control of Post-Operative Pain in Patients Undergoing Total Knee Replacement November 25, 2019 March 12, 2020
NCT05414942 Completed N/A Opioid Reduction Program for Total Knee Replacement Patients August 1, 2021 May 25, 2022
NCT05431322 Completed N/A Dexmedetomidine in Thoracoscopic Surgery: Opioid-Sparing Strategy June 1, 2022 October 31, 2023
NCT05482919 Completed The Adolescent Surgery Experience: A Mixed Methods Analysis June 14, 2022 October 15, 2023
NCT05525975 Completed N/A Opioid Consumption and Disposal After Shoulder Arthroplasty November 21, 2022 April 26, 2024
NCT05591105 Completed Morphine Consumption in the Obese Patients June 15, 2023 January 31, 2024
NCT05593341 Completed N/A Opioid Education in Total Knee Arthroplasty September 27, 2022 September 11, 2023
NCT05609955 Completed Phase 4 Effects Of Additional MgSO4 30 Mg/KgBW Intravenous and Ketorolac January 1, 2022 November 1, 2022
NCT05634291 Completed N/A Effects of the Nottingham Augmented Reality (AR) App for Arthritis Hand Joint Pain June 13, 2022 July 21, 2023
NCT05668845 Completed N/A Paragastric Autonomic Neural Blockade as Part of Combined Anesthesia. February 1, 2023 May 1, 2023
NCT05669066 Completed N/A Meditation and Opioid Consumption in Total Joint Replacement Patients Undergo Primary Total Hip and Knee Replacement July 10, 2017 December 16, 2021
NCT05693402 Completed Opioid-Free Anesthesia in Modified Radical Mastectomy January 1, 2018 December 1, 2020
NCT05698927 Completed N/A Analgesic Effects of Intrathecal Morphine and Bilateral Erector Spina Plane Block in Elective Cesarean Section February 1, 2023 September 30, 2023
NCT05706285 Completed Comparing Intrathecal Morphine With Erector Spina Plane Block in Open Gastrectomy Surgery February 15, 2023 February 1, 2024
NCT05808127 Completed N/A Guiding Aging Long-Term Opioid Therapy Users Into Safer Use Patterns August 9, 2023 May 9, 2024
NCT05818969 Completed N/A Effects of Hypnosis Therapy on Outcomes in Total Knee Replacement February 1, 2022 December 31, 2023
NCT05845177 Completed Persistent Pain After Hip Replacement September 4, 2023 November 1, 2023
NCT05946733 Completed N/A Two Approaches of Transversus Abdominis Block (TAP ) in Laparoscopic Cholecystectomy November 26, 2022 January 25, 2024
NCT06040307 Completed N/A Guiding Opioid Administration in Patients With Regional Anesthesia December 18, 2023 May 6, 2024
NCT06045078 Completed N/A Aromatherapy in Total Knee Replacement October 3, 2023 April 1, 2024
NCT06216210 Completed Assessing the Impact of Opioid-Free Anesthesia Using the Modified Mulimix Technique. April 22, 2022 October 4, 2023
NCT05412342 Enrolling by invitation Characterizing the Association Between Preoperative Depressive Symptoms and Opioid Use/Misuse After Surgery May 10, 2019 June 2024
NCT04500613 Enrolling by invitation N/A Erector Spinae Plane Blocks for Adolescent Idiopathic Scoliosis February 22, 2021 January 2024
NCT04971902 Enrolling by invitation Pharmacist-led Pharmacogenomic Clinical Service Within the Program of All-inclusive Care for the Elderly July 1, 2021 August 31, 2024
NCT05704764 Enrolling by invitation N/A Using the Ending Self-Stigma Intervention to Reduce Internalized Stigma Among People Living With HIV Who Use Substances February 17, 2023 December 31, 2025
NCT04680221 Enrolling by invitation Phase 4 Stopping Opioid Overuse in Obstetrics To Halt Exposure Trial March 1, 2021 June 1, 2024
NCT05539924 Enrolling by invitation Phase 3 Pregabalin Versus Gabapentin Opioid Sparing Effect in Discectomy September 15, 2022 November 1, 2022
NCT05896878 Enrolling by invitation N/A The Effects of Daily Anti-inflammatory Supplementation on Foundation Pain Index Scores in Chronic Opiate Patients July 10, 2023 August 2024
NCT05297396 Enrolling by invitation N/A Slow Opioid Tapering Pilot Study of Patients Using Chronic Opioid Therapy July 1, 2022 July 2024
NCT06139666 Enrolling by invitation Phase 4 The Effect of Liposomal Bupivacaine Nerve Block (Exparel) in Rotator Cuff Surgery July 11, 2019 June 1, 2025
NCT06133933 Enrolling by invitation Total Shoulder Arthroplasty Preoperative Pain Threshold and Association With Postoperative Opioid Consumption May 21, 2021 May 21, 2025
NCT05644587 Enrolling by invitation Phase 4 Novel Induction to Buprenorphine/Naloxone February 6, 2023 December 31, 2023
NCT06118073 Enrolling by invitation N/A Effect of Mindfulness on Pain After Total Knee Arthroplasty November 5, 2023 November 30, 2024
NCT05875857 Enrolling by invitation N/A Patient Utilization of Opioid Destruction Bags in the Post op Period June 19, 2023 March 2025
NCT04804072 Enrolling by invitation N/A INTEGRA: A Vanguard Study of Health Service Delivery in a Mobile Health Delivery Unit June 2, 2021 September 30, 2024
NCT05974423 Enrolling by invitation Phase 4 Randomized Trial of Narcotic vs Non-Narcotic Pain Modulation After Labrum Repair December 16, 2022 December 1, 2025
NCT04655339 Not yet recruiting Phase 2/Phase 3 Laparoscopic Transversus Abdominis Plane (TAP) Block to Reduce Post-operative Opioids December 10, 2020 July 1, 2024
NCT06137924 Not yet recruiting Phase 3 Intraoperative Autonomic Neural Blockade December 2, 2023 May 2, 2024
NCT04944225 Not yet recruiting N/A Opioid Reduction Strategy South Western Ontario November 1, 2024 March 1, 2025
NCT06337968 Not yet recruiting N/A CPB for Arthroscopic Hip Surgery May 1, 2024 May 31, 2025
NCT06113211 Not yet recruiting Phase 4 Nonopioid Pain Control Regimen After Open Reduction and Internal Fixation of Traumatic Fractures June 15, 2024 September 15, 2025
NCT06103370 Not yet recruiting N/A Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation August 2024 November 2028
NCT06100172 Not yet recruiting N/A Transcutaneous Auricular Neurostimulation After Lumbar Fusion Surgery May 2024 March 2025
NCT05276089 Not yet recruiting N/A GP Remote Consultation to Reduce Opioid Prescribing February 1, 2023 June 1, 2023
NCT05256394 Not yet recruiting N/A Patient-Centered Chronic Pain Care April 15, 2024 August 31, 2024
NCT05962671 Not yet recruiting Phase 4 Opioid-sparing Versus Sevoflurane Anesthesia on Early Postoperative Hypoventilation in Laparoscopic Bariatric Surgery August 10, 2023 March 30, 2024
NCT06063499 Not yet recruiting N/A HMP for Addictions Study June 2024 October 2024
NCT03804619 Not yet recruiting N/A Accelerated Intermittent Theta-Burst Stimulation for Opiate Use Disorder June 1, 2024 December 1, 2025
NCT06456190 Not yet recruiting N/A Testing STAR and TexSTAR: A Video and Text Messaging Intervention September 1, 2024 June 1, 2025
NCT05445700 Not yet recruiting N/A The Effects of Frailty on Opioid Consumption July 15, 2022 September 15, 2022
NCT06358040 Not yet recruiting N/A Opioid Dispenser for Microdiscectomy/Laminectomy July 2024 September 2025
NCT06285032 Not yet recruiting N/A Decreasing Loneliness to Optimize Pain Care June 2024 May 2026
NCT05900791 Not yet recruiting Persistent Pain After Knee Replacement November 1, 2023 June 30, 2024
NCT05611749 Not yet recruiting Phase 2 Duloxetine Impact on Postoperative Pain Control and Outcomes November 15, 2022 September 30, 2024
NCT06420336 Not yet recruiting N/A QL vs LAI for Palatoplasty July 1, 2024 July 30, 2026
NCT06270147 Not yet recruiting Phase 2 Timing of TAP Blocks in Bariatric Surgery March 4, 2024 June 28, 2024
NCT05850468 Not yet recruiting N/A Effectiveness of Combining Erector Spinea Block With Non Opioid Infusions as Opioid Free Anesthesia in Spine Surgeries. May 2023 November 2023
NCT05594459 Not yet recruiting N/A Early Treatment With Invasive Technique in Cancer Pain Management November 25, 2022 December 30, 2024
NCT05997355 Not yet recruiting N/A Preoperative Gabapentin for Cosmetic Breast Surgery September 1, 2023 July 31, 2024
NCT06231992 Not yet recruiting N/A Opioid Free Anaesthesia Versus Opioid Based Anesthesia for Laparscopic Cholecystectomy January 31, 2024 July 2024
NCT06231849 Not yet recruiting Gut Microbiota Dysbiosis in Opioid Use Disorders: Implications for Clinical Symptoms and Relapse Rate. February 2024 April 2026
NCT06015711 Not yet recruiting N/A The Effect of Preoperative Maxigesic® on Intraoperative Remifentanil Requirement August 30, 2023 December 31, 2024
NCT06425718 Not yet recruiting N/A Comparison of Postoperative Analgesia Methods in Elective Cesarean Section Surgeries May 15, 2024 June 30, 2024
NCT06299137 Not yet recruiting N/A Ultrasound Guided Serratus Anterior Plane Block in ED Patients With Rib Fractures August 1, 2024 October 2025
NCT06008496 Recruiting Patient Reported Outcomes, Postoperative Pain and Pain Relief After Day Case Surgery (POPPY) January 15, 2024 February 1, 2025
NCT04912531 Recruiting N/A Virtual Reality and Olfactory Stimuli Multimodal Intervention to Reduce Post-Operative Pain and Anxiety in Patients Undergoing Cardiothoracic Surgery October 1, 2022 June 30, 2025
NCT04925427 Recruiting N/A Reducing Opioid Mortality in Illinois August 10, 2021 August 30, 2026
NCT04927143 Recruiting Phase 2 Encouraging Abstinence Behavior in a Drug Epidemic September 15, 2021 December 2024
NCT04928157 Recruiting Phase 2 Prospective Randomized Trial of CPAP for SDB in Patients Who Use Opioids August 10, 2021 September 1, 2024
NCT03596424 Recruiting N/A Dexmedetomidine and Ketamine in VATS Surgery February 1, 2018 July 1, 2025
NCT06023225 Recruiting Sex Hormones, Postoperative Pain and Opioid Use September 1, 2023 July 1, 2027
NCT06032559 Recruiting Phase 3 Implementation and Effectiveness of Mindfulness Oriented Recovery Enhancement as an Adjunct to Methadone Treatment September 4, 2023 March 30, 2027
NCT03616236 Recruiting Phase 3 Buprenorphine for Probationers and Parolees: Bridging the Gap Into Treatment July 1, 2022 June 30, 2026
NCT06033599 Recruiting Phase 3 Motivational Interviewing and Mindfulness-Oriented Recovery Enhancement September 5, 2023 June 30, 2027
NCT04967352 Recruiting Predicting Chronic Pain Following Breast Surgery July 19, 2021 December 31, 2023
NCT03675386 Recruiting N/A Reducing Opioid Use for Chronic Pain Patients Following Surgery September 24, 2018 May 2024
NCT04973748 Recruiting N/A Conditioned Open-label Placebo (COLP) for Peri-operative Pain Management in Patients With Head and Neck Cancer February 7, 2023 November 15, 2024
NCT04974463 Recruiting Predicting Chronic Opioid Use Following Lower Extremity Joint Arthroplasty July 19, 2021 December 31, 2023
NCT05058287 Recruiting Phase 3 Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression November 5, 2021 December 31, 2024
NCT05078398 Recruiting N/A Postoperative Opt-In Narcotics Treatment in Breast June 1, 2022 January 1, 2024
NCT05976646 Recruiting Phase 1/Phase 2 Phase Ib/2a Drug-drug Interaction Study of a Combination of 45mg Dextromethorphan With 105 mg Bupropion September 18, 2023 January 2025
NCT04528173 Recruiting Phase 4 Opioid-Free Anesthetic for Tonsillectomy July 22, 2020 December 31, 2023
NCT05708521 Recruiting Phase 4 Personalization of Opioid Prescription Following Orthognathic Surgery April 24, 2023 June 2026
NCT05711056 Recruiting N/A Rural Expanded Access to OUD Care & Linkage Using Toxicologists for Telehealth Initiated Treatment August 30, 2023 August 2026
NCT05736211 Recruiting N/A Organization-level Youth Engagement Approach for Substance Misuse Prevention March 14, 2024 March 31, 2025
NCT04588389 Recruiting Phase 3 Comparison of Quadratus Lumborum Block Types December 1, 2020 December 31, 2022
NCT04592978 Recruiting N/A Personalized Feedback Intervention for Alcohol and Opioid Use Among Adults With Chronic Pain July 30, 2021 June 30, 2024
NCT04598074 Recruiting N/A Opioid Package Prototype (OPP) September 7, 2021 May 2025
NCT04601064 Recruiting N/A Peer Supported Collaborative Care Mental Health and Substance Use Disorder Care April 20, 2022 December 15, 2026
NCT05766631 Recruiting Phase 3 Treating Polysubstance Use Using a Novel Digital Technology July 26, 2023 September 29, 2027
NCT05774197 Recruiting N/A Psychological Intervention Using Smartphone Technology to Alleviate Malignant Pain May 4, 2023 July 2024
NCT05799339 Recruiting Optimizing CAB-LA as PrEP for Women Who Inject Drugs January 13, 2022 December 2024
NCT04601506 Recruiting N/A PRescribing INterventions for Chronic Pain Via the Electronic Health Record Study - Primary Care Providers August 26, 2020 September 2023
NCT04603417 Recruiting N/A Pain Avoidance Behavior and Its Relation to Risk for Opioid Use in Chronic Pain Patients August 15, 2020 July 31, 2025
NCT05804591 Recruiting Phase 4 Pregabalin in the Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy (LSG). April 24, 2023 August 1, 2025
NCT05805423 Recruiting N/A ENDOblock: Bilateral Superficial Cervical Blocks With Local Wound Infiltration in Thyroid Surgery April 17, 2023 November 2024
NCT05828121 Recruiting N/A POINT - Preventing an Opioid Epidemic in Norway: Focusing on Treatment of Chronic Pain October 1, 2022 June 1, 2025
NCT05834478 Recruiting Phase 3 Non-invasive Vagal Nerve Stimulation in Opioid Use Disorders UH3 February 20, 2024 December 2026
NCT04641221 Recruiting N/A Optimization and Multi-Site Feasibility of Yoga for Chronic Pain in People in YOGAMAT-II - Phase II February 20, 2022 March 31, 2025
NCT06434233 Recruiting N/A Opioid Use After Laparoscopic Salpingectomy April 25, 2024 June 2025
NCT05875207 Recruiting N/A Physical Therapy Integrated With Mindfulness for Patients With Chronic Pain and Opioid Treatment August 14, 2023 November 30, 2025
NCT04678960 Recruiting N/A Preventing Opioid Use Among Justice-involved Youth as They Transition to Adulthood Leveraging Safe Adults (LeSA) February 15, 2021 August 31, 2024
NCT05877157 Recruiting Pain AND Opioids After Surgery September 25, 2023 September 30, 2025
NCT04698746 Recruiting N/A PENG vs Intra-articular Injection for Hip Arthroscopy January 20, 2021 April 2024
NCT04749628 Recruiting Phase 4 Cannabidiol for Bilateral Total Knee Arthroplasty November 2, 2022 November 2024
NCT04764825 Recruiting Phase 4 Methadone for Spinal Fusion Surgery. February 26, 2021 May 1, 2024
NCT05905419 Recruiting N/A Neuroimaging of Opioid Phase (OPAL) June 1, 2023 June 30, 2027
NCT04798469 Recruiting Phase 2 Pain Alleviation With Testosterone in Opioid-Induced Hypogonadism January 10, 2022 April 30, 2025
NCT04801498 Recruiting Chronic Pain, Opioid Use, and Epidermal Nerve Fiber Density December 7, 2020 June 30, 2024
NCT05908097 Recruiting N/A Enhancing Prospective Thinking in Early Recovery (PARK) April 4, 2023 September 1, 2024
NCT04811014 Recruiting Phase 4 Young Houston Emergency Opioid Engagement System April 19, 2021 August 31, 2027
NCT05930184 Recruiting Phase 2/Phase 3 Laparoscopic Guided Peri-wound Transversus Abdominis Plane Block With Bupivacaine Versus Local Wound Infiltration on Post-op Opioid Use in Laparoscopic Sleeve Gastrectomy April 29, 2023 December 2024
NCT05936190 Recruiting N/A Comparison of the Effect of Lidocaine Infusion Applied at Different Doses During Lumbar Spinal Surgery on Hemodynamics and Postoperative Pain February 10, 2023 January 31, 2024
NCT04827992 Recruiting N/A Evaluation of Medical Cannabis and Prescription Opioid Taper Support for Reduction of Pain and Opioid Dose in Patients With Chronic Non-Cancer Pain August 23, 2021 June 30, 2025
NCT04837014 Recruiting N/A Eliminating Narcotic Prescriptions From Outpatient Minimally Invasive Gynecologic Surgery July 4, 2022 July 2024
NCT06443892 Recruiting Comparison of Pain Relief After Hip Fracture Surgery: Hip and Groin Nerve Block May 1, 2023 July 1, 2024
NCT05980546 Recruiting Phase 4 Genicular and Anterior Femoral Cutaneous Nerve Blocks for Total Knee Arthroplasty June 7, 2023 May 22, 2026
NCT05981105 Recruiting N/A Enhanced Recovery After Major Surgery and Chronic Pain for Total Knee Arthroplasty June 12, 2023 June 12, 2025
NCT04894864 Recruiting Phase 4 Opioid Free Anesthesia-Analgesia Strategy and Surgical Stress in Elective Open Abdominal Aortic Aneurysm Repair October 8, 2020 October 8, 2027
NCT04895306 Recruiting Phase 2 Testosterone Replacement to Alleviate Pain in Postmenopausal Women (TRAPP Trial) November 16, 2022 April 30, 2025
NCT05995535 Recruiting Phase 2 Pregabalin Plus Lofexidine for the Outpatient Treatment of Opioid Withdrawal January 1, 2024 August 31, 2026
NCT04902339 Recruiting N/A Near-infrared Spectroscopy-based Neurofeedback as Adjunct to Mindfulness-Oriented Recovery Enhancement in Persons With Chronic Pain May 1, 2021 August 30, 2023
NCT05995873 Recruiting N/A A Project to Test the Efficacy and Safety of An Innovative Treatment for Opiate Use Disorders. January 22, 2024 August 30, 2024
NCT05098561 Recruiting N/A Music Therapy for Post-cardiac Surgery Pain Management October 15, 2018 September 21, 2023
NCT06043830 Recruiting Phase 2 Managing Opioid Related Sleep Apnea With Acetazolamide October 18, 2023 June 1, 2025
NCT03784573 Recruiting N/A Canine-Assisted Anxiety Reduction In Emergency Care January 7, 2019 July 31, 2024
NCT06456268 Recruiting N/A VibraCool Device to Reduce Pain and Opioid Use After Anterior Cruciate Ligament Reconstruction June 30, 2024 July 15, 2025
NCT05153785 Recruiting Phase 2/Phase 3 Perioperative Intravenous Lidocaine in Liver Surgery November 15, 2021 December 31, 2026
NCT06055205 Recruiting N/A A Pain and Coordination Plan for Reduced Opioid Use After Accidental Injuries September 25, 2023 December 2028
NCT05172739 Recruiting Phase 4 Opioid Free Anaesthesia-Analgesia Strategy on Surgical Stress and Immunomodulation in Elective VATS-Lobectomy for NSCLC October 1, 2021 November 1, 2026
NCT05192434 Recruiting N/A Trauma Intervention to Optimize PrEP Among Women Who Inject Drugs June 17, 2022 April 30, 2026
NCT03823534 Recruiting Phase 3 Post-Op Pain Control for Prophylactic Intramedullary Nailing. February 20, 2019 October 1, 2024
NCT03858231 Recruiting Phase 4 Opioids Versus Non-Opioids Postoperative After Knee Arthroscopic Surgery October 29, 2018 January 2026
NCT05208892 Recruiting N/A Dexmedetomidine Use in SZMN Blocks for Pediatric T&A Pain Control January 29, 2024 December 2025
NCT06077422 Recruiting Phase 2/Phase 3 Exparel vs. Marcaine ESP Block for Post-cardiac Surgical Pain January 11, 2024 April 5, 2025
NCT05260047 Recruiting N/A Culturally Responsive Community Driven Substance Use Recovery for Black and Latinx Population July 20, 2022 October 1, 2026
NCT06082141 Recruiting N/A Effect of Adding TTPB to SAPB in Breast Cancer Surgery July 12, 2023 June 2024
NCT06084520 Recruiting Translation and Validation of the COMM and ASI-SR December 1, 2023 December 31, 2026
NCT03981445 Recruiting N/A Integrated HIV Prevention and HCV Care for PWID November 14, 2019 September 2024
NCT05286112 Recruiting N/A Mindfulness for Pain and Suicide March 6, 2023 February 28, 2025
NCT05299515 Recruiting N/A Peer Activate: Trial of Peer-Delivered Behavioral Activation for Methadone Adherence April 5, 2022 March 1, 2025
NCT05304403 Recruiting The Association of Microbiome Patterns With Chronic Opioid Use April 1, 2022 June 1, 2025
NCT05351905 Recruiting N/A Improving Pain Disability With the Use of Oral Cannabinoids November 22, 2022 December 2024
NCT04044820 Recruiting N/A Opioid Use Post-Discharge After Ambulatory Distal Arm Surgery March 4, 2019 December 31, 2023
NCT05370924 Recruiting Assessment of the Development of Postoperative Persistent Postoperative Pain February 20, 2021 June 30, 2024
NCT05380531 Recruiting N/A Personalized Perioperative Analgesia Platform (PPAP) for Cesarean Section December 5, 2022 October 30, 2026
NCT05384860 Recruiting N/A Incorporating Acupuncture Into ERAS for Ambulatory Total Hip Replacement (THR) Surgery July 6, 2022 August 2024
NCT04094701 Recruiting N/A Hip Arthroscopy Postoperative Opioid Demands October 21, 2020 March 2026
NCT04095624 Recruiting N/A Does Preoperative Pain Medication Management Influence Surgical Outcomes in Spinal Fusion September 9, 2019 July 1, 2024
NCT04110080 Recruiting N/A Enhanced Recovery After Surgery in Kidney Transplant Donors September 12, 2019 June 12, 2023
NCT03032822 Recruiting Opioid Consumption in Cystectomy Patients January 17, 2018 December 31, 2024
NCT05411159 Recruiting N/A Effect of Opioid-free Anesthesia on PostOperative Nausea and Vomiting in Patients Undergoing Video-assisted Thoracoscopic Surgery June 7, 2022 December 31, 2024
NCT06215053 Recruiting N/A Pre-post Erector Spine Plane Block-spinal Surgery January 1, 2024 January 1, 2026
NCT06464393 Recruiting N/A Opioid-based Versus Opioid-free Endotracheal Intubation March 20, 2024 March 20, 2025
NCT05463367 Recruiting Phase 2 Project 1 Aim 2, Adaptations of the Brain in Chronic Pain With Opioid Exposure January 1, 2021 August 1, 2023
NCT05485012 Recruiting Phase 1 Reinforcing Effects of Marijuana and Opioids August 3, 2023 October 2025
NCT05506878 Recruiting N/A Auriculo-Nerve Stimulation on Post-Operative Opioid Requirement October 24, 2022 September 30, 2026
NCT06230003 Recruiting N/A Efficacy of Erector Spinae Plane (ESP) Block in Patients With Inflammatory Bowel Disease (IBD) July 21, 2021 September 30, 2024
NCT05558397 Recruiting Phase 4 Epidural Association of Morphine and Ropivacaine for Cancer Pain Treatment April 1, 2018 August 2023
NCT04300751 Recruiting Phase 1 Alcohol and Opioids March 24, 2021 November 2024
NCT05585788 Recruiting N/A Opioid Dispensing Device for Post-Operative Pain in Cancer Patients Patients October 5, 2020 May 1, 2026
NCT05589753 Recruiting Phase 1/Phase 2 Sleep Disordered Breathing With Opioid Use May 2, 2019 December 31, 2024
NCT04393207 Recruiting Phase 4 TAP Block Using Liposomal Bupivacaine for Post-cesarean Delivery Analgesia- Walking Towards Recovery February 1, 2022 May 30, 2025
NCT04401917 Recruiting Early Phase 1 Evaluation of Neuroinflammation FNOS PET/CT in HIV (+) and (-) Subjects With OUD and Healthy Controls December 7, 2020 December 7, 2025
NCT05597878 Recruiting Phase 2/Phase 3 Opioid-Free Pain Control Regimen Following Robotic Radical Prostatectomy April 18, 2023 February 2025
NCT05599672 Recruiting N/A Co-Use of Opioid Medications and Alcohol Prevention Study May 1, 2023 April 30, 2025
NCT05607381 Recruiting N/A Neural Mechanisms of Meditation for Opioid-Treated Chronic Low Back Pain November 30, 2022 June 2027
NCT04469868 Recruiting N/A No Opioids PrescrIptions On Discharge After Surgery December 15, 2018 April 2024
NCT05639712 Recruiting Phase 4 Affective Effects of Pre-surgery Opioids: a Randomized, Doubleblind Placebo-controlled Trial December 13, 2022 December 2025
NCT06345872 Recruiting N/A Improving Sleep and Reducing Opioid Use in Individuals With Chronic Pain April 2024 July 2028
NCT04512144 Recruiting N/A Mindfulness in Endometrial and Cervical Cancer July 25, 2020 July 30, 2024
NCT06346860 Recruiting N/A Comparing Intrathecal Morphine With Modified Thoracoabdominal Nerve Block Through Perichondral Approach in Major Abdominal Surgery April 15, 2024 November 2024
NCT05001789 Suspended N/A Cognitive Functioning in Opioid Use Disorder September 21, 2021 November 30, 2024
NCT03187080 Suspended Phase 4 Enhanced Recovery Strategies in Elective Breast Surgery April 2024 April 2026
NCT05422001 Terminated Phase 4 Low-dose KETamine as an Adjunct to MOrphine for Acute Pain in the ED May 31, 2022 August 15, 2023
NCT03624985 Terminated Phase 4 The Effect of Perioperative Intravenous Lidocaine Infusion on Opioid Consumption After Lumbar Spine Surgery June 4, 2018 October 14, 2019
NCT03552120 Terminated N/A Serving Women Using Opioids During Pregnancy April 23, 2018 February 5, 2021
NCT03677830 Terminated Phase 4 Postoperative Pain Control & Relief in Neonates April 19, 2019 March 7, 2024
NCT04791761 Terminated Phase 1/Phase 2 Non-Opioid Pain Medications After Intracapsular Adenotonsillectomy April 13, 2021 July 3, 2023
NCT03922620 Terminated Phase 4 Liposomal Bupivacaine vs Peripheral Nerve Block January 23, 2020 June 30, 2021
NCT03618823 Terminated Phase 1/Phase 2 Non-opioids for Analgesia After Adenotonsillectomy in Children October 25, 2018 May 18, 2020
NCT04203199 Terminated N/A H-coil TMS to Reduce Pain: A Pilot Study Evaluating Relative Efficacy of the H1 vs H7 Coil January 18, 2022 October 6, 2022
NCT04766996 Terminated Phase 4 PROUD Study - Preventing Opioid Use Disorders May 17, 2021 December 27, 2021
NCT06217380 Terminated N/A Feasibility and Acceptability of Oxygen Saturation Monitoring Using Masimo SafetyNet Alert (MSNA) in a Supportive Housing Program September 20, 2023 February 15, 2024
NCT03248765 Terminated Human Brain Adaptation to Chronic Pain and Its Effects on Opioid Use August 30, 2017 September 11, 2020
NCT03656679 Terminated N/A Paravertebral Versus Pectoralis Block for Post Mastectomy Pain October 18, 2018 February 28, 2020
NCT03638635 Terminated Phase 4 Standard Bupivacaine vs Liposomal Bupivacaine in Colorectal Patients May 14, 2018 January 16, 2019
NCT03185117 Terminated Opioid Consumption After Hospital Discharge in Orthopedic Surgery September 1, 2016 July 24, 2019
NCT03588806 Terminated Phase 4 Use of Xtampza ER to Overcome Difficulties in Swallowing Opioid Pills May 1, 2018 October 31, 2019
NCT03992079 Terminated N/A A Multimodal Enhanced Recovery Program in Anorectal Surgery June 20, 2019 May 21, 2020
NCT03426137 Terminated Phase 2 Relieving Acute Pain (RAP) Study: A Pilot Study September 17, 2018 January 21, 2020
NCT03732469 Terminated Phase 4 Rectal Acetaminophen Use During Oocyte Retrievals to Reduce Post-Operative Opioid Utilization November 1, 2019 March 1, 2021
NCT04990804 Terminated Phase 4 Opioid Free vs. Standard Perioperative Pain Regimen for Anterior Cervical Discectomy and Fusion (ACDF) Surgery August 1, 2021 February 1, 2022
NCT04517110 Terminated Phase 3 Perioperative Pregabalin for Reducing Opioid Consumption After Cardiac Surgery April 9, 2021 September 7, 2022
NCT04258436 Terminated N/A Serratus Anterior Plane Block for Management of Post Thoracotomy Pain December 9, 2019 January 1, 2021
NCT03794882 Terminated Phase 4 Impact of Quadratus Lumborum Block on Recovery Profile After Ventral Hernia Repair May 6, 2019 March 12, 2020
NCT03798405 Terminated N/A Reactive vs. Proactive Pain Control in IBD January 1, 2019 July 1, 2022
NCT03886753 Terminated Pharmacokinetic (PK) and Pharmacodynamics (PD) Study of Ilera Specific Products May 15, 2019 June 30, 2020
NCT03730402 Terminated Phase 4 Laparoscopic Assisted Plane Block (LAPB) Trial February 4, 2019 April 14, 2021
NCT04033562 Terminated Phase 4 The Analgesic Efficacy of Continuous Sub-fascial Bupivacaine Infusion and Lidocaine Patches in Post-cesarean Patients With Opiate Use Disorder: A Comparative Efficacy Analysis January 15, 2020 May 17, 2021
NCT03749564 Terminated N/A Influence of Opioid Use on the Effects of Spinal Manipulative Therapy for Low Back Pain January 17, 2019 March 3, 2020
NCT04360421 Terminated Phase 4 Use of Long-acting Bupivacaine In Lower Extremity Amputation April 21, 2020 August 1, 2023
NCT04086394 Unknown status N/A PECS Block in Partial Mastectomy for Postoperative Pain Control September 1, 2019 November 1, 2020
NCT03106129 Unknown status Opioid Requirements Post Discharge of Patients Having Total Knee Arthroplasty (TKA) February 9, 2017 December 30, 2022
NCT04649281 Unknown status N/A Insomnia and Sleep Disturbances in Chronic Pain Patients - Relation to Physical Activity Level and Opioid Use October 12, 2020 December 31, 2021
NCT05322564 Unknown status N/A Standardization of Post-operative Opiate Prescriptions for Same-day Ankle and Wrist Fracture Surgeries May 2022 December 2022
NCT05337956 Unknown status N/A Ultrasound-guided Erector Spinae Plane Block Using Catheter for Video-assisted Thoracoscopy April 2022 May 2023
NCT03418636 Unknown status N/A The Staying Safe Intervention January 31, 2018 May 31, 2021
NCT04945525 Unknown status N/A Comparing a Patient Self-Assessment Software to Treatment as Usual in Opioid Prescriber and Patient Opioid Outcomes May 26, 2021 July 31, 2022
NCT05367050 Unknown status N/A Impact of a Behavioral Tele-health Program on the Quality of Recovery for Patients Undergoing Total Joint Replacement Surgery May 4, 2021 April 2023
NCT04435236 Unknown status N/A Cervical Erector Spinae Block Versus Interscalene Block for Shoulder Surgery October 1, 2021 May 1, 2022
NCT04764916 Unknown status Phase 3 Evaluation of Exparel Adductor Canal Field Block for Pain Control After ACL Reconstruction February 16, 2021 March 2, 2022
NCT04438746 Unknown status N/A Chronic Pain, Opioids, and Anger Treatment July 1, 2020 January 1, 2023
NCT03545516 Unknown status Phase 2 Wound Infiltration as Part of an Opioid Free Pain Management Pathway Following Cesarean Delivery September 17, 2018 November 1, 2018
NCT03412448 Unknown status The Prevalence of Chronic Pain and Continued Opioid Use After Cardiac Surgery June 1, 2017 August 1, 2018
NCT03248076 Unknown status Effect of Fentanyl on Main Opioid Receptor (OPRM1) on Human Granulosa Cells. April 1, 2017 October 10, 2018
NCT04503720 Unknown status N/A CLoWI Versus PCA Morphine for Pain Control After Major Abdominal Surgery December 1, 2017 June 2022
NCT04751344 Unknown status Phase 4 Liposomal Bupivacaine Versus Bupivacaine Plain for Operative Pain Management of Forefoot Surgery June 16, 2020 June 2022
NCT05437861 Unknown status N/A Return to Work - Will Brief Intervention Reduce Opioid-induced Back Pain? August 2022 January 2023
NCT04868552 Unknown status N/A Naloxone Education in Total Joint Patients September 2021 December 2022
NCT04189523 Unknown status N/A Does Early Administration of Ultrasound Guided Regional Anesthesia for Long Bone Fractures Effect Long Term Patient Opioid Usage September 1, 2019 June 2020
NCT04459923 Unknown status N/A Postoperative Pain Scores and Opioid Consumption in Video Assisted Thoracic Surgery June 20, 2020 May 25, 2022
NCT03545321 Unknown status N/A RESPOND TO PREVENT: Stepwise Pharmacy Naloxone Study July 9, 2019 November 2022
NCT05080348 Unknown status N/A Effectiveness of iPACK on Postoperative Pain From Hamstring Autograft Following ACL Repair December 2021 May 2022
NCT03749811 Unknown status N/A Pupillometry-guided Remifentanil Infusion Versus Conventional Administration in Children December 4, 2018 November 18, 2021
NCT05091138 Unknown status N/A Are Adductor Canal Blocks With Bupivacaine and Added Magnesium Better at Managing Post-operative Pain Than Bupivacaine and Added Buprenorphine in Patients Undergoing Same-day Discharge Total Knee Arthroplasty? October 12, 2021 October 1, 2022
NCT04462250 Unknown status N/A Mobile Health (mHealth) App for Safe Opioid Use August 24, 2020 May 31, 2022
NCT05103787 Unknown status N/A Impact of Bilateral Deep Parasternal Intercostal Plane Block on Intraoperative Opioid Consumption in Open Heart Surgery October 4, 2021 July 4, 2022
NCT04259333 Unknown status Phase 4 Celecoxib vs. Acetaminophen/Codeine/Caffeine for Post-operative Analgesia in Rhinoplasty. March 1, 2020 December 1, 2020
NCT04275258 Unknown status N/A Collaborative Opioid Taper After Trauma: Preventing Opioid Misuse and Opioid Use Disorder June 1, 2020 January 31, 2022
NCT03825471 Unknown status N/A Cranial Electrotherapy Stimulation on Anesthetics Consumption and Postoperative Pain January 14, 2019 December 31, 2020
NCT05196386 Unknown status N/A Usual Care Intervention Research Evaluating the Impact of a Personalized Pharmaceutical Plan on the Duration of Opioid Treatment in Non-cancerous Pain August 6, 2020 March 2023
NCT03198208 Unknown status Intraoperative Fentanyl Dose on Respiratory Complications January 1, 2007 June 30, 2018
NCT03105232 Unknown status Opioid-Redox Study August 20, 2021 December 1, 2022
NCT04729244 Unknown status Phase 1 The Study of Hemp Oil CBD for Evaluation of Efficacy and Safety in Treatment of Pain, Anxiety and Insomnia Management September 1, 2021 February 1, 2022
NCT03859089 Unknown status Cannabis for Opioid Substitution Trial October 10, 2017 October 31, 2019
NCT03870685 Unknown status Phase 4 Surgical Site Infiltration of Exparel vs TAP Block With Exparel in Patients Undergoing Laparotomy Via Midline Incision July 5, 2018 December 31, 2021
NCT05235503 Unknown status Phase 4 Influence of Δ9-tetrahydrocannabinol (THC) on Oxycodone Induced Ventilatory Depression in Healthy Volunteers December 9, 2021 June 2023
NCT03894592 Unknown status N/A Virtual Reality Analgesia In Trauma Rehab August 1, 2019 October 2020
NCT03394911 Unknown status Phase 3 Healthy Adult Male Facial Skin Surface Lipid Pheromone p.o. to Treat Opioid Addiction December 31, 2020 November 2021
NCT03927326 Unknown status N/A Postoperative Analgesia in Laparoscopic Abdominal Surgery After Exparel Via TAP or Local Infiltration August 2019 July 2020
NCT05022745 Unknown status Phase 4 ERAS Protocol for Single-level Posterior Lumbar Arthrodesisprospective Study. July 8, 2021 December 2022
NCT03931343 Unknown status N/A Comparison of Thoracolumbar Interfascial and Erector Spinae Plane Block on Analgesic Efficiency of After Spinal Surgery December 2020 April 2021
NCT03933345 Unknown status Overdose Risk Management and Naloxone April 5, 2019 August 31, 2023
NCT04314505 Unknown status Phase 4 Opioid-Sparing Protocol Comparing With Opioid-based Protocol After Bilateral Total Knee Arthroplasty March 20, 2020 August 20, 2020
NCT05271331 Unknown status N/A ESP Block Versus Wound Infiltration for Laminectomy May 23, 2022 May 20, 2023
NCT03534102 Withdrawn Phase 4 Can Simplified and More Detailed Instructions Affect Post-Operative Narcotic Consumption June 6, 2022 September 1, 2024
NCT03303664 Withdrawn N/A Inpatient Multimodal Path to RecOVEry July 11, 2017 February 26, 2018
NCT04740099 Withdrawn N/A Surviving Opioid Overdose With Naloxone Education and Resuscitation Trial (SOONER) December 2021 March 2023
NCT03586934 Withdrawn Phase 3 Multimodal Analgesia in Shoulder Arthroplasty June 1, 2018 June 1, 2019
NCT03352479 Withdrawn N/A Safe Return and Disposal of Unused Opioids December 1, 2017 July 30, 2018
NCT03744663 Withdrawn Phase 2 Long Acting Buprenorphine Injection Compared to Sublingual Buprenorphine/Naloxone Films June 2022 December 2022
NCT04335461 Withdrawn Early Phase 1 Postop Pain Control in Hip Fracture Surgery: Fascia Iliaca Compartment Block Versus Fracture Block August 5, 2021 March 17, 2023
NCT03036891 Withdrawn Phase 2 Naloxegol for Opioid-Related Gastroparesis December 29, 2016 September 30, 2019
NCT03563911 Withdrawn N/A Brief Mindfulness and Nutrition-Based Interventions for Chronic Pain: Strategies to Ease Pain December 12, 2018 April 1, 2020
NCT04539730 Withdrawn Phase 4 Liposomal Bupivacaine in Adductor Canal Blocks (ACB) December 1, 2021 December 1, 2022
NCT03836313 Withdrawn N/A Assessing if Cryoneurolysis Improves Prehabilitation and Decreases Pain After Surgery With Less Opioid Use in TKA Patients March 2019 June 2021
NCT04167852 Withdrawn N/A Mindfulness Meditation and Bariatric Surgery November 21, 2019 June 15, 2021
NCT03359798 Withdrawn N/A RCT of Counseling Intervention on Post-op Opiate Use December 1, 2017 December 1, 2018
NCT03857139 Withdrawn Phase 4 Opioids and Smoking Cessation December 2020 January 2023
NCT03906838 Withdrawn Early Phase 1 Regional Anesthesia Block in Fibula Free Flap Reconstruction January 1, 2020 November 30, 2020
NCT03907813 Withdrawn Phase 4 Liposomal Bupivacaine After Cesarean Delivery May 1, 2019 July 31, 2020
NCT03388814 Withdrawn Early Phase 1 Speeding Recovery From Pain and Opioid Use November 2018 June 2020
NCT04113252 Withdrawn N/A Impact of Coaching Patients on Pain Control With and Without Financial Incentivization May 2022 August 2022