Alzheimer disease
Information
- Disease name
- Alzheimer disease
- Disease ID
- Description
Disease area statistics
Chromosome band
| Gene symbol | Chromosome | Start | Stop | The number of variant |
|---|---|---|---|---|
| NECTIN2 | 19 | 44,846,297 | 44,889,223 | 22 |
| SORL1 | 11 | 121,452,314 | 121,633,763 | 18 |
| TOMM40 | 19 | 44,891,254 | 44,903,689 | 10 |
| APOE | 19 | 44,905,796 | 44,909,393 | 6 |
| CLU | 8 | 27,596,917 | 27,614,700 | 6 |
| SAMD12 | 8 | 118,377,984 | 118,621,963 | 6 |
| UGT2B4 | 4 | 69,480,165 | 69,495,905 | 4 |
| ANK3 | 10 | 60,026,298 | 60,389,875 | 4 |
| CBLC | 19 | 44,777,890 | 44,800,652 | 4 |
| FAM47E | 4 | 76,251,721 | 76,283,783 | 4 |
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT04699786 | Active, not recruiting | N/A | Returning Research Results That Indicate Risk of Alzheimer Disease Dementia to Healthy Participants in Longitudinal Studies | February 19, 2021 | January 31, 2026 |
| NCT05524181 | Active, not recruiting | N/A | Telehealth-enabled Integrated Palliative Care for People With Dementia | June 29, 2022 | August 14, 2024 |
| NCT05173922 | Active, not recruiting | N/A | "Safety in Dementia": An Online Caregiver Intervention | May 22, 2022 | August 3, 2024 |
| NCT06083350 | Active, not recruiting | N/A | Effects of Yeast Beta-glucan on Cognitive Function in Patients With Mild Cognitive Impairment | June 27, 2023 | June 30, 2025 |
| NCT05356702 | Active, not recruiting | N/A | The Brain Health Study: A Pragmatic, Patient-Centered Trial | June 29, 2022 | July 31, 2025 |
| NCT04121858 | Active, not recruiting | N/A | Brain Safe: Consumer Intervention to Reduce Exposure to Drugs Linked to Alzheimer's Disease | October 16, 2019 | October 31, 2024 |
| NCT03622905 | Active, not recruiting | N/A | ADvance II Study: DBS-f in Patients With Mild Alzheimer's Disease | August 1, 2019 | October 1, 2025 |
| NCT03556280 | Active, not recruiting | N/A | Multi-Center Study of Sensory Stimulation to Improve Brain Function | April 24, 2018 | September 2021 |
| NCT05454540 | Active, not recruiting | N/A | Repetitive TMS of the Posterior DMN in AD | October 1, 2018 | December 31, 2022 |
| NCT03741543 | Active, not recruiting | N/A | Learning and Coping With Early Stage Dementia | March 3, 2014 | December 31, 2024 |
| NCT04451408 | Active, not recruiting | Phase 1 | A Study of LY3372993 in Participants With Alzheimer's Disease (AD) and Healthy Participants | July 7, 2020 | October 15, 2024 |
| NCT04118764 | Active, not recruiting | N/A | Non-invasive Blood-brain Barrier Opening in Alzheimer's Disease Patients Using Focused Ultrasound | August 6, 2020 | December 2023 |
| NCT05026177 | Active, not recruiting | Phase 3 | Simufilam 50 mg or 100 mg for Mild-to-Moderate Alzheimer's Disease | November 18, 2021 | May 2025 |
| NCT05058040 | Active, not recruiting | Phase 4 | A Clinical Study to Evaluate the Long-Term Safety Sodium Oligomannate Capsules (GV-971) | June 2, 2021 | April 2025 |
| NCT05817643 | Active, not recruiting | Phase 1 | Food Effect Study of BMS-984923 in Healthy Older Adult Volunteers | January 10, 2023 | June 15, 2024 |
| NCT04785053 | Active, not recruiting | N/A | Memory Functions in Mild Alzheimer's Disease | June 22, 2020 | September 30, 2024 |
| NCT05754021 | Active, not recruiting | A Practical Platform for In-Home Remote Monitoring of Cognitive Frailty | February 1, 2022 | December 31, 2024 | |
| NCT05411822 | Active, not recruiting | N/A | Understanding Circadian Responses to Light in Persons With Mild Cognitive Impairment | June 14, 2021 | April 2025 |
| NCT05834296 | Active, not recruiting | Phase 1/Phase 2 | Study in Subjects With Mild-to-Moderate Alzheimer's Dementia | July 5, 2023 | March 3, 2028 |
| NCT03960476 | Active, not recruiting | N/A | Decision Making and Implementation of Aging-in-Place/Long Term Care Plans Among Older Adults | January 13, 2020 | February 28, 2025 |
| NCT03634007 | Active, not recruiting | Phase 1/Phase 2 | Gene Therapy for APOE4 Homozygote of Alzheimer's Disease | November 6, 2019 | November 2024 |
| NCT05557617 | Active, not recruiting | Periodontitis and Periodontal Bacteria in Dementia | October 30, 2020 | December 31, 2024 | |
| NCT04994483 | Active, not recruiting | Phase 3 | Simufilam 100 mg for Mild-to-Moderate Alzheimer's Disease | November 3, 2021 | October 2024 |
| NCT04042922 | Active, not recruiting | N/A | High Frequency Light and Sound Stimulation to Improve Brain Functions in Alzheimer's Disease | April 19, 2019 | April 30, 2025 |
| NCT06224920 | Active, not recruiting | Activity of Cerebral Networks, Amyloid and Microglia in Aging and Alzheimer's Disease | January 1, 2017 | March 31, 2024 | |
| NCT04088643 | Active, not recruiting | N/A | 4Hz Transcranial Alternating Current Stimulation for Patients With Mild Alzheimer's Disease | October 14, 2019 | December 2023 |
| NCT05842473 | Active, not recruiting | N/A | Long-term Effect of TMS in Primary Progressive Aphasia | February 1, 2023 | July 31, 2024 |
| NCT04482179 | Active, not recruiting | Phase 1 | Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Alzheimer Disease | February 19, 2020 | August 31, 2024 |
| NCT04592874 | Active, not recruiting | Phase 2 | A Phase 2 Study to Evaluate Efficacy and Safety of AL002 in Participants With Early Alzheimer's Disease | January 22, 2021 | October 15, 2024 |
| NCT03444181 | Active, not recruiting | N/A | ALzheimer and MUsic THerapy: Effects of Music Lessons on Brain Plasticity, Mood, and Quality of Life in Alzheimer Patients | April 11, 2018 | June 14, 2024 |
| NCT04517552 | Active, not recruiting | Investigation of Inflammation Using [C-11]-CS1P1 | November 2, 2020 | July 8, 2025 | |
| NCT03282097 | Active, not recruiting | N/A | Decisions About Cancer Screening in Alzheimer's Disease | December 1, 2017 | June 30, 2024 |
| NCT05703490 | Active, not recruiting | An Innovative Platform for Objective Monitoring of Instrumental Activities of Daily Living | November 1, 2021 | December 31, 2024 | |
| NCT05995418 | Active, not recruiting | Study on the Health Economic Burden of Alzheimer's Disease in China | July 1, 2023 | August 2024 | |
| NCT05175664 | Active, not recruiting | Novel Diagnostic and Disease Stage Biomarkers in AD | January 1, 2022 | January 1, 2025 | |
| NCT05292248 | Active, not recruiting | N/A | CONFIDENCE Financial Education for Caregivers | May 1, 2022 | March 1, 2024 |
| NCT06027320 | Active, not recruiting | N/A | The Retain Your Brain Health Study (RetainYourBrain.Com) | December 7, 2023 | September 7, 2024 |
| NCT05063539 | Active, not recruiting | Phase 2 | A Study of LY3372689 to Assess the Safety, Tolerability, and Efficacy in Participants With Alzheimer's Disease | September 16, 2021 | August 6, 2024 |
| NCT05145881 | Active, not recruiting | N/A | Effect of Probiotics in Alzheimer's Disease | April 2, 2020 | December 31, 2023 |
| NCT04322461 | Active, not recruiting | N/A | Effect of Exercise, Endocannabinoids and Ketones on Cerebral Metabolism in a Cognitive Disorders Population | May 1, 2022 | December 15, 2024 |
| NCT04270604 | Active, not recruiting | Biological Sample Collection for Research and Biobanking | February 6, 2012 | January 2030 | |
| NCT04314934 | Active, not recruiting | Phase 2/Phase 3 | OLE of Phase 2b/3 Study ANAVEX2-73-AD-004 | October 10, 2019 | July 31, 2024 |
| NCT05207397 | Active, not recruiting | Lactate for Energy and Neurocognition | April 12, 2023 | January 2025 | |
| NCT04536701 | Active, not recruiting | N/A | Learning and Improving Alzheimer's Patient-Caregiver Relationships Via Smart Healthcare Technology | February 19, 2021 | December 31, 2024 |
| NCT04437511 | Active, not recruiting | Phase 3 | A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2) | June 19, 2020 | August 22, 2025 |
| NCT04871074 | Active, not recruiting | Phase 2 | The Synapse Project | November 18, 2018 | May 2025 |
| NCT04312399 | Active, not recruiting | N/A | Hormone Replacement Trial Against ALzheimers' Disease | April 17, 2018 | December 31, 2024 |
| NCT04111211 | Active, not recruiting | Long-term Follow-up of Cognitive and Functional Evolutions of Persons With Isolated Cognitive Complaints or Mild Cognitive Deficits | December 3, 2019 | June 2025 | |
| NCT05550727 | Active, not recruiting | N/A | The PorchLight Project | September 23, 2022 | June 30, 2026 |
| NCT03062449 | Active, not recruiting | Phase 2 | Phase IIa L-serine Trial for eAD | March 1, 2017 | December 31, 2022 |
| NCT04055376 | Active, not recruiting | N/A | Daily Light and Sound Stimulation to Improve Brain Functions in Alzheimer's Disease | August 14, 2019 | April 30, 2025 |
| NCT04495686 | Active, not recruiting | N/A | An Innovative Supportive Care Model for Dementia and Traumatic Brain Injury | March 3, 2021 | September 2025 |
| NCT06209515 | Active, not recruiting | Sociodemographic Factors and Criminal Behaviour Preceding Neurodegenerative Disease - Retrospective Register Study | January 1, 2022 | December 31, 2027 | |
| NCT05004688 | Active, not recruiting | Phase 2 | A Trial to Evaluate the Effects of BCG in Adults With MCI and Mild-to-Moderate AD | March 25, 2022 | October 1, 2023 |
| NCT05768425 | Active, not recruiting | DIagnostic Biomarkers and Symptoms in Patients With Alzheimer's Disease and Lewy bodY Dementia | February 1, 2023 | December 2032 | |
| NCT04606420 | Active, not recruiting | N/A | Can Lifestyle Changes Reverse Early-Stage Alzheimer's Disease | September 8, 2018 | September 30, 2023 |
| NCT02958670 | Active, not recruiting | N/A | Imaging Tau Deposition in the Brain of Elderly Subjects | November 2016 | December 2029 |
| NCT06158789 | Active, not recruiting | N/A | Repetitive Blood Brain Barrier Opening for Alzheimer's Disease. | June 2, 2022 | January 19, 2024 |
| NCT04488419 | Active, not recruiting | Phase 2/Phase 3 | ATH-1017 for Treatment of Mild to Moderate Alzheimer's Disease | September 28, 2020 | August 2024 |
| NCT04102514 | Active, not recruiting | N/A | A Dyadic Approach for a Remote Physical Activity Intervention in Adults With AD and Their Caregivers | July 6, 2020 | August 31, 2024 |
| NCT05060848 | Active, not recruiting | Plasma Hydrogen Sulfide as a Biomarker for Alzheimer's Disease and Related Dementias | April 1, 2021 | May 2027 | |
| NCT04783350 | Active, not recruiting | N/A | Home-based Brain Stimulation for Memory | July 6, 2020 | September 30, 2024 |
| NCT05344989 | Active, not recruiting | Phase 1 | A First-in-Human Study to Assess Single Doses of APNmAb005 in Healthy Participants | May 6, 2022 | July 2024 |
| NCT03687710 | Active, not recruiting | The Comparative Effectiveness Dementia & Alzheimer's Registry | February 16, 2015 | June 30, 2026 | |
| NCT05181475 | Active, not recruiting | Phase 4 | Long-term Efficacy and Safety Study of GV-971 | December 7, 2021 | June 2025 |
| NCT05012410 | Active, not recruiting | N/A | WeCareAdvisor Study for Caregivers of People Living With Dementia | December 13, 2021 | October 2025 |
| NCT04004767 | Active, not recruiting | TRC-PAD Program: In-Clinic Trial-Ready Cohort | June 4, 2019 | April 30, 2024 | |
| NCT03330587 | Active, not recruiting | Living Alone in Old Age With Cognitive Impairment | March 1, 2016 | May 31, 2025 | |
| NCT05469360 | Active, not recruiting | Phase 1 | Study of Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of NIO752 in Early Alzheimer's Disease Participants | February 23, 2023 | October 21, 2025 |
| NCT02951598 | Active, not recruiting | A Study of Health Care Use and Costs in Participants With Early Stage Alzheimer's Disease (AD) | October 29, 2016 | April 28, 2026 | |
| NCT04619420 | Active, not recruiting | Phase 2 | A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease | January 6, 2021 | December 30, 2032 |
| NCT03617497 | Active, not recruiting | N/A | Prevalence of Epilepsy and Sleep Wake Disorders in Alzheimer Disease | December 1, 2020 | September 30, 2024 |
| NCT03116126 | Active, not recruiting | Phase 3 | Noradrenergic Add-on Therapy With Guanfacine | January 4, 2019 | August 5, 2024 |
| NCT05295615 | Active, not recruiting | N/A | Pulsed Electromagnetic Field Treatment In Patients With Alzheimer's Disease | May 1, 2023 | September 30, 2025 |
| NCT05732519 | Active, not recruiting | Turkish Speech Analysis Development Study | March 1, 2023 | December 16, 2025 | |
| NCT05696483 | Active, not recruiting | Phase 1 | Phase 1 Study of OLX-07010 in Healthy Adult and Elderly Participants | January 20, 2023 | March 1, 2025 |
| NCT04381468 | Active, not recruiting | Phase 1/Phase 2 | SEMA4D Blockade Safety and Brain Metabolic Activity in Alzheimer's Disease (AD) | July 22, 2021 | June 10, 2024 |
| NCT05522387 | Active, not recruiting | Phase 2 | An Open-Label Extension of XPro1595 in Patients With Alzheimer's Disease | February 21, 2023 | September 30, 2024 |
| NCT03821857 | Active, not recruiting | Phase 4 | Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease | June 27, 2019 | May 2025 |
| NCT03688126 | Active, not recruiting | N/A | U.S. Study to Protect Brain Health Through Lifestyle Intervention to Reduce Risk | January 8, 2019 | July 2025 |
| NCT05516147 | Active, not recruiting | N/A | SAFE at Home: A Service to Provide Social Engagement to Community-Dwelling Persons With Dementia | January 19, 2024 | March 31, 2024 |
| NCT04837937 | Active, not recruiting | N/A | Negotiation Training for Caregiver Communication in AD | September 1, 2023 | March 31, 2025 |
| NCT05364307 | Active, not recruiting | Identification of Patients With a High Probability of Meeting Eligibility Criteria for an Alzheimer's Disease Clinical Trial (APHELEIA) | June 13, 2022 | December 2025 | |
| NCT02675270 | Active, not recruiting | N/A | Rehabilitation and Prophylaxis of Anomia in Primary Progressive Aphasia | November 2011 | June 30, 2024 |
| NCT04710550 | Active, not recruiting | Phase 1 | Exploring the Utility of [18F]3F4AP for Demyelination Imaging in Controls, Neurodegeneration and Traumatic Brian Injury | January 25, 2021 | December 1, 2025 |
| NCT03282916 | Active, not recruiting | Phase 2 | Anti-viral Therapy in Alzheimer's Disease | February 12, 2018 | December 2024 |
| NCT03347084 | Active, not recruiting | N/A | Deep Brain Stimulation With LIFUP for Mild Cognitive Impairment and Mild Alzheimer's Disease | November 10, 2018 | October 2023 |
| NCT05959239 | Available | TB006 Expanded Access (EA) Compassionate Use | |||
| NCT03539380 | Available | TRx0237 for the Treatment of Early and Mild-Moderate Alzheimer's Disease | |||
| NCT04606953 | Completed | N/A | Working Memory Training in Older Adults With Mild Cognitive Impairment : Impacts on Cognition and Ecological Activities | February 1, 2019 | September 27, 2021 |
| NCT03287765 | Completed | Evaluating the Relationship Between Tau PET Imaging and CSF Biomarkers of AD (Alzheimer Disease) in Humans | May 2016 | July 19, 2021 | |
| NCT05525377 | Completed | N/A | Better Living With Non-memory-led Dementia | June 21, 2022 | February 9, 2023 |
| NCT00630851 | Completed | Phase 3 | A Study of the Efficacy and Safety of Aricept in Patients With Severe Alzheimer's Disease Who Are Living in Skilled Nursing Homes | October 2002 | October 2004 |
| NCT03581643 | Completed | Validation of the Montreal Cognitive Assessment in Patients With Mild and Major Neurocognitive Disorder | March 6, 2017 | May 8, 2018 | |
| NCT03417986 | Completed | Phase 2 | Clinical Trial to Explore the the Amyloid Beta Draining Effect of Thiethylperazine (TEP) in Subjects With Newly Diagnosed Early-to-mild Dementia Due to Alzheimer's Disease (AD) in Comparison to Healthy Volunteers | November 24, 2017 | October 22, 2021 |
| NCT00076440 | Completed | Phase 2 | Antigonadotropin-Leuprolide in Alzheimer's Disease Drug INvestigation (ALADDIN) VP 104 Study | December 2003 | March 2007 |
| NCT05172687 | Completed | The Effect of De-Prescribing Antipsychotics on Health and Quality of Life for People With Dementia | April 2015 | December 31, 2018 | |
| NCT04271046 | Completed | N/A | STAR Caregivers - Virtual Training and Follow-up | September 1, 2020 | September 21, 2023 |
| NCT00480701 | Completed | Phase 2 | Evaluation of 123-I Iodobenzovesamicol (IBVM) and SPECT Imaging of Healthy Subjects and Patients With Alzheimer Disease | February 2007 | October 2011 |
| NCT01348061 | Completed | Evaluating Cerebrospinal Fluid Biomarkers in Alzheimer's, Progressive Supranuclear Palsy Subjects, and Controls | July 2011 | July 2013 | |
| NCT04524351 | Completed | Phase 1/Phase 2 | Posiphen® Dose-Finding, Biomarker Study in Early Alzheimer's and Parkinson's Patients | August 14, 2020 | January 31, 2022 |
| NCT00752232 | Completed | Phase 2 | Study Evaluating ACC-001 in Japanese Patients With Mild To Moderate Alzheimer's Disease | December 2008 | July 2012 |
| NCT03279523 | Completed | F 18 T807 PET (Positron Emission Tomograph )Scan for HIV Infected & Uninfected | May 3, 2016 | May 23, 2018 | |
| NCT05153161 | Completed | Phase 1 | Memesto Wearable Device for Persons With Dementia | August 31, 2022 | November 30, 2023 |
| NCT03786510 | Completed | N/A | A Study on the Effectiveness of Multidomain Intervention Program for Reducing Risks of Dementia | November 1, 2016 | July 31, 2017 |
| NCT02624778 | Completed | Phase 1 | A Study of LY3002813 in Participants With Memory Damage Due to Alzheimer's Disease (AD) or AD | December 22, 2015 | August 28, 2019 |
| NCT03430648 | Completed | Is Tau Protein Linked to Mobility Function? | September 7, 2017 | September 27, 2021 | |
| NCT03841539 | Completed | N/A | Nutrition Interventions for Cognitive Enhancement | March 7, 2019 | March 22, 2023 |
| NCT01978548 | Completed | Phase 1 | A Study to Evaluate the Effects of JNJ-54861911 on Amyloid Beta Processing in Cerebrospinal Fluid and Plasma in Patients With Prodromal Alzheimer's Disease | December 2013 | April 2015 |
| NCT04794634 | Completed | N/A | Relationship Between Alzheimer Disease and Diminution of the Three Macular Nervous Retinal Layers | March 9, 2021 | September 1, 2023 |
| NCT02323217 | Completed | Early Phase 1 | I2PETHV - Imidazoline2 Binding Site in Healthy Volunteers | January 2015 | July 2016 |
| NCT05159596 | Completed | N/A | In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment: Spanish Language Homes | September 20, 2022 | October 30, 2023 |
| NCT03971994 | Completed | N/A | Emotion and Attention in Alzheimer's Disease (ATEMMA) | May 31, 2019 | November 30, 2021 |
| NCT04247347 | Completed | N/A | Tailored Health Self-Management Interventions for Highly Distressed Caregivers: Family Members of Persons With Dementia | August 29, 2019 | June 21, 2022 |
| NCT04715750 | Completed | Phase 1 | Evaluation of Imaging Characteristics of [18F]PI-2620 PET in AD and PSP Patients Using High and Low Specific Activity | November 12, 2020 | October 26, 2022 |
| NCT03537729 | Completed | N/A | Effects of Visual Cues and Education for People Who Live Within Long Term Care Communities to Assist in Wayfinding | April 1, 2019 | October 23, 2023 |
| NCT02444637 | Completed | Phase 4 | Open Label Trial of Rivastigmine Patch in Subjects With Mild to Moderate Stage AD Having Coexisting svCVD | April 2015 | March 2019 |
| NCT00488007 | Completed | N/A | Clinical Trial on Alzheimer Disease, Presbycusis and Hearing Aids | May 2007 | September 2013 |
| NCT04602624 | Completed | Phase 2 | A Study to Evaluate the Safety and Tolerability of SAGE-718 in Participants With Mild Cognitive Impairment or Mild Dementia Due to Alzheimer's Disease (AD) | February 2, 2021 | September 21, 2021 |
| NCT00481520 | Completed | Phase 2 | Study Evaluating the Safety,Tolerability, PK and PD of SAM-531 in the Subjects With Mild to Moderate Alzheimer's Disease | June 2007 | January 2008 |
| NCT03991988 | Completed | Phase 2 | Montelukast Therapy on Alzheimer's Disease | September 25, 2019 | November 18, 2022 |
| NCT00249158 | Completed | Phase 3 | A Study of the Effectiveness and Safety of Risperidone in the Treatment of Behavioral Disturbances in Patients With Dementia | March 1998 | February 2001 |
| NCT01860625 | Completed | Phase 1 | A Phase I Clinical, Dose Escalation Study of the Safety, Tolerability and Pharmacokinetics of Donepezil Patch in Healthy Male Subjects | April 2013 | February 2014 |
| NCT03538522 | Completed | Phase 2 | A Double-Blind, Placebo-Controlled Safety and Efficacy Study of NA-831 | September 15, 2018 | October 30, 2019 |
| NCT04080544 | Completed | Phase 2 | Cognitive Decline and Alzheimer's Disease in the Dallas Lifespan Brain Study | January 15, 2019 | June 30, 2022 |
| NCT03022968 | Completed | Phase 2 | Tau Brain Imaging in Typical and Atypical Alzheimer's Disease (AD) | January 10, 2017 | November 25, 2019 |
| NCT04325204 | Completed | N/A | Faith-Based Toolbox for African Americans With Dementia | August 19, 2021 | July 13, 2023 |
| NCT03901456 | Completed | N/A | Care to Plan: a Tailored Resource for Family Members of Persons With Dementia | September 1, 2019 | May 24, 2022 |
| NCT03560245 | Completed | Phase 2 | A Study of Bryostatin in Moderately Severe to Severe Alzheimer's Disease Subjects Not On Memantine | June 20, 2018 | July 25, 2019 |
| NCT00291161 | Completed | N/A | Partners in Dementia Care: A Telephone Care Consultation Intervention Provided to Veterans in Partnership With Local Alzheimer's Association Chapters | December 2006 | February 2011 |
| NCT03638323 | Completed | Age-related Hearing Loss and Lexical Disorders | August 27, 2018 | January 31, 2019 | |
| NCT00253214 | Completed | Phase 3 | Placebo-Controlled Evaluation of Galantamine in the Treatment of Alzheimer's Disease: Safety and Efficacy of a Controlled-Release Formulation | March 2001 | July 2002 |
| NCT01138111 | Completed | Phase 1 | Florbetaben (BAY94-9172) PET (Positron Emission Tomography) Imaging in MCI (Mild Cognitive Impairment) Patients | June 2008 | December 2011 |
| NCT03033875 | Completed | N/A | Testing Tele-Savvy, an On-line Psychoeducation Program for Dementia Family Caregivers | May 18, 2017 | December 4, 2020 |
| NCT05402566 | Completed | MRI Assessment of Impaired Glucose Metabolism in Alzheimer's Disease | December 22, 2022 | October 27, 2023 | |
| NCT05248672 | Completed | Phase 1 | Study to Assess the Pharmacokinetics of CT1812 in Older Healthy Volunteers | February 15, 2022 | June 1, 2022 |
| NCT00236431 | Completed | Phase 3 | A Study to Evaluate the Efficacy and Safety of Galantamine in Patients With Mild Cognitive Impairment | May 2001 | December 2003 |
| NCT04842734 | Completed | N/A | Comparison of the Effect of Online Physical Exercise and Computerized Cognitive Stimulation in Patients With Alzheimer's Disease | April 27, 2021 | December 25, 2021 |
| NCT05125536 | Completed | N/A | The Effect of Music in Alzheimer's Patients | April 16, 2018 | July 13, 2018 |
| NCT05307692 | Completed | Phase 2 | A Study of Seltorexant in Participants With Probable Alzheimer's Disease | May 19, 2022 | November 10, 2023 |
| NCT05352529 | Completed | N/A | Assistive Technology and Reduced Caregiver Burden | February 2, 2021 | September 1, 2021 |
| NCT03901105 | Completed | Phase 3 | Evaluation of Flortaucipir PET Signal and Cognitive Change in Early Alzheimer's Disease | March 28, 2019 | April 28, 2019 |
| NCT00063310 | Completed | Phase 2 | ALADDIN Study: Antigonadotropin-Leuprolide in Alzheimer's Disease Drug INvestigation | March 2003 | February 2006 |
| NCT03300180 | Completed | N/A | Caregiver Outcomes of Alzheimer's Disease Screening | October 15, 2018 | September 30, 2023 |
| NCT03757325 | Completed | Phase 1 | Study to Evaluate DNL747 in Subjects With Alzheimer's Disease | February 13, 2019 | December 5, 2019 |
| NCT04733989 | Completed | A Biomarker Database to Investigate Blood-Based and Digital Biomarkers in Participants Screened for Alzheimer's Disease (Bio-Hermes) | April 21, 2021 | November 11, 2022 | |
| NCT03752463 | Completed | Phase 2 | NMDA Enhancer for the Treatment of Mild Alzheimer's Disease | May 22, 2015 | July 31, 2021 |
| NCT03971123 | Completed | Phase 1 | Study to Compare the Pharmacokinetics of Tricaprilin Formulations and a Placebo on Ketone Body Production | August 30, 2019 | May 26, 2020 |
| NCT03095417 | Completed | N/A | Improving the Recovery and Outcome Every Day After the ICU | September 25, 2017 | December 15, 2022 |
| NCT03698695 | Completed | Phase 1 | A Pharmacodynamics, Safety, and Pharmacokinetics Study of THN201 Versus Donepezil in Healthy Male Volunteers | September 27, 2018 | December 20, 2019 |
| NCT03313518 | Completed | N/A | Therapeutic Role of Transcranial DCS in Alzheimer | August 12, 2016 | October 10, 2017 |
| NCT00970333 | Completed | Phase 1 | Evaluation of [18F] FEPPA and PET Imaging as a Marker of Inflammation in Subjects With Neurological Conditions | August 2009 | October 2010 |
| NCT02340195 | Completed | Phase 1 | Pharmacokinetic Properties of Idalopirdine (Lu AE58054) in Subjects With and Without Impaired Kidney Function | January 2015 | |
| NCT05383053 | Completed | Evaluating the Efficacy of Artificial Intelligence-based Computer Aided Diagnosis Software That Assists in Determining Whether or Not to Conduct Amyloid PET for the Diagnosis of Alzheimer's Disease by Predicting Amyloid PET Positivity in Mild Cognitive Impairment Patients | July 22, 2022 | September 8, 2022 | |
| NCT00281749 | Completed | Phase 1 | Telephone Call From Acute Care Physicians to Long Term Care Physicians: Impact on Transitional Care of Elderly Patients | October 2006 | |
| NCT04044131 | Completed | Phase 2 | Metabolic Cofactor Supplementation in Alzheimer's Disease (AD) and Parkinson's Disease (PD) Patients | December 2, 2019 | April 20, 2021 |
| NCT05150990 | Completed | N/A | Technology and Family Thriving Study | October 12, 2021 | March 16, 2024 |
| NCT05033262 | Completed | N/A | Our Care Wishes - Dementia | October 7, 2020 | September 8, 2021 |
| NCT00089882 | Completed | Risk Evaluation and Education for Alzheimer's Disease (REVEAL) II | May 2003 | September 2006 | |
| NCT00951197 | Completed | Evaluation of Alteration by Magnetic Resonance Imaging (MRI) in Dementia Among Elderly Subjects | April 2009 | March 2011 | |
| NCT03551769 | Completed | Phase 1 | Pharmacokinetics of Tricaprilin Including Food Effect on Ketone Body Production | August 5, 2018 | August 27, 2018 |
| NCT00253227 | Completed | Phase 3 | A Study of the Safety and Effectiveness of a Flexible Dose of Galantamine Versus Placebo in the Treatment of Patients With Alzheimer's Disease | July 1997 | December 1998 |
| NCT02414282 | Completed | F 18 T807 Tau PET Imaging of Progressive Posterior Cortical Dysfunction (IND 123119, Protocol E) | March 2015 | October 20, 2020 | |
| NCT04686838 | Completed | N/A | REmote Assessment and Dynamic Response Intervention II | July 1, 2021 | November 25, 2022 |
| NCT01023685 | Completed | Phase 2 | To Investigate the Safety and Tolerability of Repeated Subcutaneous Injections of CAD106 in Alzheimer's Patients | December 2009 | February 2012 |
| NCT03328195 | Completed | N/A | Vielight Neuro RX Gamma - Feasibility Pilot | December 4, 2017 | February 28, 2022 |
| NCT06217146 | Completed | N/A | A Medical Cannabis Oil for Treatment of Agitation and Disruptive Behaviors in Subjects With Dementia. | October 12, 2022 | March 10, 2024 |
| NCT00304629 | Completed | Phase 3 | Long-term Safety and Efficacy of Galantamine in Alzheimer's Disease | March 2000 | March 2002 |
| NCT05159583 | Completed | N/A | In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment: Rural Homes | August 22, 2022 | January 30, 2024 |
| NCT05449626 | Completed | Validity and Reliability of Turkish Version of Bayer Activities of Daily Living Scale | July 26, 2022 | January 6, 2023 | |
| NCT03699644 | Completed | Multimodal Ocular Imaging in Neurodegeneration | January 4, 2019 | April 3, 2019 | |
| NCT04403165 | Completed | N/A | Locus-coeruleus Function in Normal Elderly and AD Risk | August 6, 2020 | March 26, 2024 |
| NCT04070378 | Completed | Phase 2 | Study of Daratumumab in Patients With Mild to Moderate Alzheimer's Disease | November 6, 2019 | August 15, 2023 |
| NCT03577262 | Completed | Early Phase 1 | A Non-therapeutic Feasibility Study of the Radioligand [11C]-UCB-J for Imaging Synaptic Density | July 23, 2018 | August 2, 2019 |
| NCT01020838 | Completed | Phase 3 | Phase III Study of Florbetaben (BAY94-9172) PET Imaging for Detection/Exclusion of Cerebral β-amyloid Compared to Histopathology | November 2009 | December 2013 |
| NCT00000179 | Completed | Phase 3 | Agitation in Alzheimer's Disease | ||
| NCT00719394 | Completed | Phase 1 | Study Evaluating Safety of GSI 136 in Young and Elderly Japanese Males | March 2008 | August 2008 |
| NCT01436188 | Completed | Early Phase 1 | A Study to Measure CSF Proteins in Elderly Healthy Volunteers and Volunteers With Mild Cognitive Impairment or Alzheimer's Disease | September 2011 | June 2013 |
| NCT00301574 | Completed | Phase 3 | An Efficacy and Safety Study of Galantamine for the Treatment of Patients With Alzheimer's Disease. | April 2001 | February 2004 |
| NCT02529436 | Completed | Overuse of Antidepressant in Patients With Alzheimer Disease | April 2015 | December 2015 | |
| NCT02337907 | Completed | Phase 2 | BI 409306 in Patients With Cognitive Impairment Due to Alzheimer's Disease. | January 21, 2015 | October 10, 2017 |
| NCT00034567 | Completed | Healthy Aging and Memory Study | |||
| NCT01807026 | Completed | Phase 1 | A Study of LY2886721 in Healthy Participants and Participants Diagnosed With Alzheimer's Disease | March 2013 | May 2013 |
| NCT01039194 | Completed | Phase 1 | Drug-Drug Interaction to Study the Effect of BMS-708163 on Pharmacokinetics (PK) of Galantamine Extended Release (ER) | January 2010 | April 2010 |
| NCT05462977 | Completed | N/A | Rhythmically Entrained Exercise in Community-Dwelling Older Adults | May 1, 2022 | September 30, 2023 |
| NCT01345110 | Completed | A Longitudinal Multidimensional Population Study on Brain Aging | November 2009 | December 2015 | |
| NCT00000172 | Completed | Phase 3 | Evaluation of Galantamine in the Treatment of Alzheimer's Disease | ||
| NCT00255866 | Completed | Phase 2/Phase 3 | Improving Mood and Behavior in Assisted Living Residents Through Skills Training for Their Caregivers | January 2004 | December 2006 |
| NCT03955380 | Completed | Phase 1 | MAD Phase I Study to Investigate Contraloid Acetate | December 12, 2018 | April 3, 2019 |
| NCT04562506 | Completed | N/A | Repetitive Transcranial Magnetic Stimulation With H-coil in Alzheimer's Disease | October 21, 2010 | September 8, 2014 |
| NCT03034746 | Completed | N/A | Impact of Physical Activity on Successful Aging | September 2013 | October 2016 |
| NCT03322462 | Completed | Phase 2 | Tau Screening Study in Patients With Early Symptomatic AD | November 21, 2017 | August 31, 2018 |
| NCT00216515 | Completed | Phase 4 | The Efficacy of Galantamine on the Attention and the Frontal Function of the Patients With Dementia of Alzheimer Type | March 2004 | November 2005 |
| NCT03587376 | Completed | Early Phase 1 | Characterization of T-Cell Response in Participants Previously Treated With JNJ-54861911 (Atabecestat) | May 30, 2018 | August 23, 2018 |
| NCT04394845 | Completed | Phase 1 | A Study of the Biodistribution and Safety of [18F]GTP1 in Healthy Japanese Participants | August 11, 2020 | October 9, 2020 |
| NCT02377206 | Completed | Early Phase 1 | Neuroinflammation and Cognitive Decline in Alzheimer Disease | April 6, 2016 | December 4, 2019 |
| NCT02129452 | Completed | Olfactory Neuroepithelial Tissue of Alzheimer Disease | January 2013 | February 2015 | |
| NCT03405662 | Completed | N/A | Impact of Photobiomodulation (PBM) on Biomarkers of Alzheimer's Disease | August 16, 2018 | January 1, 2021 |
| NCT03008161 | Completed | Phase 1 | Multiple Dose Safety Study of NPT088 in Patients With Mild to Moderate Probable Alzheimer's Disease | December 2016 | February 6, 2019 |
| NCT06275243 | Completed | N/A | Polymorphism of ApoE in Alzheimer's Disease: Genetic Study in Castile and Leon (Spain) | July 6, 2022 | March 22, 2024 |
| NCT04621448 | Completed | N/A | Moving Together: An Online Group Movement Program for People Living With Memory Loss and Caregivers | November 18, 2020 | May 12, 2023 |
| NCT00479219 | Completed | Phase 1 | Study Evaluating GSI-953 in Healthy Young and Alzheimer's Patients | May 2007 | October 2007 |
| NCT06194552 | Completed | Phase 1 | A Multiple Dose Study of the Safety and Pharmacokinetics of NTRX-07 | September 6, 2022 | June 30, 2023 |
| NCT02918539 | Completed | Registry of Amyloid Positive Patients for Alzheimer's Disease Drug Research Trials | October 2016 | October 18, 2017 | |
| NCT00191009 | Completed | Phase 2/Phase 3 | Adding Atomoxetine To Standard Medication Treatment In Patients With Alzheimer's Disease | October 2003 | January 2006 |
| NCT00955409 | Completed | Phase 2 | Long Term Extension Study Evaluating Safety, Tolerability and Immunogenicity Of ACC-001 In Subjects With Mild To Moderate Alzheimer's Disease | November 5, 2009 | December 17, 2013 |
| NCT02612688 | Completed | N/A | Pragmatic Trial of Video Education in Nursing Homes | March 1, 2016 | May 31, 2019 |
| NCT00464334 | Completed | Phase 1 | A Study of V950 in People With Alzheimer Disease (V950-001 AM7) | March 2007 | January 2012 |
| NCT01209156 | Completed | Phase 1 | Evaluation of [18F] PBR111 and PET as a Marker of Inflammation in Subjects With Neurological Conditions | March 2010 | June 2013 |
| NCT00499642 | Completed | Phase 1 | Study Evaluating the Effect of Lecozotan SR on the QTc Interval | June 2007 | August 2007 |
| NCT05108922 | Completed | Phase 3 | A Study of Donanemab (LY3002813) Compared With Aducanumab in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 4) | November 16, 2021 | September 19, 2023 |
| NCT01772095 | Completed | ADVANCE Study: Alzheimer Disease eVAluation iN Clinical PracticE | February 2013 | November 2013 | |
| NCT05080777 | Completed | N/A | Pilot Pragmatic Clinical Trial to Embed Tele-Savvy Into Health Care Systems | September 28, 2021 | June 5, 2023 |
| NCT04040348 | Completed | Phase 1 | Alzheimer's Disease Stem Cells Multiple Infusions | October 8, 2019 | April 25, 2023 |
| NCT03089918 | Completed | Phase 1 | A Study to Investigate the Regional Brain Kinetics of Brain Drug Transporters Using P-glycoprotein and Breast Cancer Resistance Protein Substrates and by Using the Positron Emission Tomography Ligand 11C-JNJ-63779586 in the Human Brain | May 17, 2017 | August 24, 2018 |
| NCT04972643 | Completed | N/A | The Protective Effect of Omega-3 Fatty Acid on Cognitive Function Among Patients With Mild Dementia | September 23, 2012 | September 23, 2018 |
| NCT03075007 | Completed | Brain Vascular Disease in Aging and Dementia | May 23, 2017 | August 31, 2019 | |
| NCT05159557 | Completed | N/A | In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment: Wearables | August 22, 2022 | March 25, 2024 |
| NCT00006399 | Completed | Phase 2 | Effects of Estrogen on Memory in Post-Menopausal Women and Patients With Alzheimer's Disease | September 1999 | March 2004 |
| NCT03748706 | Completed | Phase 2 | PTI-125 for Mild-to-moderate Alzheimer's Disease Patients | March 7, 2019 | May 8, 2019 |
| NCT00480870 | Completed | Phase 4 | The Effect of Anticholinesterase Drugs on Sleep in Alzheimer's Disease Patients | April 1999 | January 2005 |
| NCT00009204 | Completed | Phase 3 | Serotonergic Pharmacotherapy for Agitation of Dementia | September 1995 | April 2002 |
| NCT00066157 | Completed | Phase 2/Phase 3 | Alzheimer's Disease: Therapeutic Potential of Estrogen | September 2001 | December 2007 |
| NCT00814502 | Completed | N/A | Zolpidem CR and Hospitalized Patients With Dementia | December 2008 | December 2013 |
| NCT02494531 | Completed | N/A | Illiteracy and Vulnerability to Alzheimer's Disease: Evaluation of Amyloid Pathology by PET Imaging | December 12, 2015 | May 6, 2020 |
| NCT02839187 | Completed | N/A | Neuro Imaging and Multimodal Alzheimer's Disease | June 2010 | May 2012 |
| NCT05077631 | Completed | Phase 1 | Study to Evaluate the Effects of Single Ascending Oral Doses of ACD856 on Safety, Tolerability and Pharmacokinetics | February 15, 2021 | February 22, 2022 |
| NCT02750306 | Completed | Phase 3 | Safety and Efficacy of Suvorexant (MK-4305) for the Treatment of Insomnia in Participants With Alzheimer's Disease (MK-4305-061) | May 23, 2016 | September 30, 2018 |
| NCT01707719 | Completed | Isolated Erythrocyte Membrane Susceptibility to Photo-oxidative Stress in Alzheimer's Disease | June 2015 | November 2018 | |
| NCT01518374 | Completed | Phase 2 | Clinical Evaluation of Florbetapir F 18 (18F-AV-45) | December 2009 | May 3, 2017 |
| NCT01901263 | Completed | Patients With Behavioural Symptoms and Hospitalized in Cognitive and Behavioural Units | October 2012 | October 2015 | |
| NCT02958930 | Completed | N/A | Safety and Efficacy of Transcranial Electromagnetic Treatment Against Alzheimer's Disease | October 1, 2017 | January 11, 2019 |
| NCT05019014 | Completed | Olfactory Deficits in Neurologic Disease | August 10, 2011 | July 3, 2020 | |
| NCT03903211 | Completed | Phase 2 | Longitudinal Changes of [18F]PI-2620 Positron Emission Tomography in Subjects With Cognitively Normal, Mild Cognitive Impairment and Alzheimer's Disease | April 9, 2019 | February 28, 2021 |
| NCT00462917 | Completed | N/A | REVEAL III: Risk Evaluation and Education for Alzheimer's Disease | March 2007 | October 2009 |
| NCT01639586 | Completed | N/A | Comparison for the Patient With Alzheimer Disease the Impact of Three Different Groups of Patient Care | August 2011 | April 2013 |
| NCT03447613 | Completed | Retinal Nerve Fiber Layer Thickness and Cerebrospinal Fluid Aβ/Tau | August 1, 2013 | December 31, 2014 | |
| NCT00183378 | Completed | N/A | Using Behavioral Programs to Treat Sleep Problems in Individuals With Alzheimer's Disease | September 2005 | March 2011 |
| NCT00366483 | Completed | Phase 1 | Study Evaluating the Safety of Lecozotan SR in Healthy Young and Elderly Subjects | May 2006 | |
| NCT04828122 | Completed | Amyloid Prediction in Early Stage Alzheimer's Disease From Acoustic and Linguistic Patterns of Speech | November 19, 2020 | August 6, 2021 | |
| NCT04044495 | Completed | N/A | Sleep, Rhythms and Risk of Alzheimer's Disease | September 9, 2019 | February 22, 2022 |
| NCT03656159 | Completed | N/A | Evaluation of a New CBT for People With Alzheimer's Disease and Their Caregivers | January 2017 | June 2019 |
| NCT03090854 | Completed | Cholinergic Markers Alzheimer's Disease | November 8, 2017 | January 12, 2021 | |
| NCT04931459 | Completed | Phase 1 | A Study to Evaluate the Safety, Tolerability, and Blood Levels of ACU193 in Participants With MCI or Mild AD | June 21, 2021 | June 12, 2023 |
| NCT05885620 | Completed | N/A | SAMi Intervention Study to Evaluate Smartwatch Interventions in Persons With MCI and Dementia | November 10, 2020 | November 10, 2022 |
| NCT03389698 | Completed | Developing Advanced Blood-Brain Barrier Permeability Imaging for Early AD | December 18, 2018 | July 11, 2023 | |
| NCT03323502 | Completed | N/A | Aligning Patient Preferences: a Role Offering Alzheimer's Patients, Caregivers, and Healthcare Providers Education and Support | February 1, 2020 | August 31, 2022 |
| NCT05686044 | Completed | Phase 2/Phase 3 | A Dose-ranging Study to Investigate Efficacy of Buntanetap in Mild to Moderate AD | April 1, 2023 | February 13, 2024 |
| NCT02317523 | Completed | N/A | Alzheimer's Caregiver Coping: Mental and Physical Health | September 2014 | June 30, 2019 |
| NCT00065169 | Completed | N/A | Delaying Alzheimer Disease Symptoms With Anti-Inflammatory Drugs | November 2000 | November 2005 |
| NCT03605667 | Completed | Phase 2 | Study of BHV-4157 in Alzheimer's Disease | July 31, 2018 | December 23, 2021 |
| NCT03977584 | Completed | Phase 2 | Tau Positron Emission Tomography (PET) Longitudinal Substudy Associated With: Study of Crenezumab Versus Placebo in Preclinical Presenilin1 (PSEN1) E280A Mutation Carriers in the Treatment of Autosomal-Dominant Alzheimer's Disease | June 10, 2019 | April 19, 2022 |
| NCT00042172 | Completed | Phase 4 | Treatment for Early Memory Loss | June 2002 | September 2004 |
| NCT00035204 | Completed | Phase 4 | A Study of the Effects on Sleep, Attention, and Gastrointestinal Tolerance of Galantamine and Donepezil in Patients With Alzheimer's Disease | May 2003 | |
| NCT02959489 | Completed | N/A | Risk Evaluation and Education for Alzheimer's Disease - the Study of Communicating Amyloid Neuroimaging (REVEAL-SCAN) | November 2016 | April 29, 2021 |
| NCT05215782 | Completed | Eye to Brain Connection | March 14, 2022 | March 16, 2023 | |
| NCT04093882 | Completed | The Relevance of the Blood-brain Barrier to Cognitive Dysfunction and Alzheimer's Disease | September 12, 2019 | September 30, 2021 | |
| NCT03824197 | Completed | N/A | Auburn University Research on Olive Oil for Alzheimer's Disease (AU-ROOAD) | May 7, 2019 | December 31, 2020 |
| NCT03016702 | Completed | N/A | The Cognitive Resilience Study | February 27, 2017 | August 9, 2017 |
| NCT00059410 | Completed | Alzheimer's Disease Treatment and Illness Perceptions Survey (TIPS) II | January 2003 | September 2005 | |
| NCT00831506 | Completed | Phase 1 | Dimebon (PF-01913539)-Digoxin Drug-Drug Interaction Study In Healthy Subjects | February 2009 | May 2009 |
| NCT00765115 | Completed | Phase 1 | A Study of Healthy Subjects to Assess the Effect of LY450139 on Amyloid Beta Peptide Production Rate and or Dose Response. | July 2006 | September 2007 |
| NCT00088387 | Completed | Phase 2 | Effect of Lithium and Divalproex in Alzheimer's Disease | July 2004 | March 2005 |
| NCT05418296 | Completed | N/A | Assessing a Novel Virtual Environment That Assists With Activities of Daily Living | June 9, 2022 | October 30, 2023 |
| NCT03112096 | Completed | Phase 1 | A Phase I [18F]THK-5351 Positron Emission Tomography Study in Healthy Subjects and Alzheimer's Disease | May 17, 2017 | August 31, 2018 |
| NCT04335110 | Completed | N/A | Assessing Acceptability, Cost, and Efficacy of STELLA-Support Via Technology | March 24, 2021 | June 15, 2023 |
| NCT03565809 | Completed | Quality of the Management of Diabetes in Elderly People With Dementia in France | May 2, 2017 | December 31, 2018 | |
| NCT02444078 | Completed | N/A | Effects of Exercise on Functional Ability in People With Dementia in Nursing Homes:a Cluster Randomised Controlled Trial | August 2015 | September 2017 |
| NCT02062099 | Completed | Phase 1 | PET Imaging of the Translocator Proteine Ligands (TSPO) With [18 F] DPA-714 Biomarker of NeuroInflammation in Cognitive Decline (NIDECO) | January 2014 | May 22, 2018 |
| NCT02462291 | Completed | N/A | New Approach for Treatment of Behavioral Disorders in Alzheimer's Disease (Alzheimer's Behavioral and Cognitive Disorders) | June 2015 | December 2015 |
| NCT05527288 | Completed | N/A | A Bridging Study on Efficacy and Safety of [18F]Florbetaben PET for Diagnosis of Alzheimer Disease Subjects in Chinese Population | January 28, 2021 | September 12, 2021 |
| NCT03493282 | Completed | Phase 1/Phase 2 | Effect of CT1812 Treatment on Brain Synaptic Density | March 28, 2018 | October 16, 2020 |
| NCT05680532 | Completed | N/A | The Improvement of Black Raspberry in Obese and Mild AZ Patients Infected With H. Pylori | November 11, 2021 | August 4, 2022 |
| NCT04726527 | Completed | Clinical Evaluation of Florbetapir in Primary Progressive Aphasia | March 15, 2012 | February 28, 2017 | |
| NCT00287248 | Completed | Phase 1 | Assess 123-I IMPY and SPECT Imaging as a Tool to Detect β-Amyloid in the Brain | February 2006 | March 2008 |
| NCT05783830 | Completed | Early Phase 1 | Study Evaluating the Pharmacokinetics of a Single Microdose of ACD856 | January 13, 2020 | April 18, 2020 |
| NCT00291421 | Completed | A Survey Study of the Treatment and Outcome Management in Patients Diagnosed With Alzheimer's Disease | July 2002 | May 2006 | |
| NCT03117738 | Completed | Phase 1/Phase 2 | A Study to Evaluate the Safety and Efficacy of AstroStem in Treatment of Alzheimer's Disease | May 9, 2017 | August 31, 2019 |
| NCT04597827 | Completed | Metacognition in Semantic Dementia: Comparison With Alzheimer's Disease | October 16, 2020 | April 27, 2022 | |
| NCT00071721 | Completed | Phase 3 | Valproate in Dementia (VALID) | October 2003 | December 2009 |
| NCT03384069 | Completed | N/A | CBT for African Americans With Cognitive Impairment | January 10, 2018 | November 20, 2019 |
| NCT05309369 | Completed | N/A | Musical Engagement of Brain LObes in Alzheimer's Disease Patients StudY | May 11, 2022 | March 15, 2024 |
| NCT04512040 | Completed | N/A | At-Home Telehealth Yoga for Treating Chronic Pain in People With Alzheimer's Disease and Their Caregiver's | February 25, 2021 | May 9, 2022 |
| NCT00062569 | Completed | N/A | Bathing Persons With Alzheimer's Disease aT Home (The BATH Study) | September 2002 | June 2006 |
| NCT03999879 | Completed | PhosphoRus, Proton Imaging and Amyloid BuRdEn (PREPARE) ON AMYLOID BURDEN AND COGNITION | May 1, 2019 | February 24, 2023 | |
| NCT05102045 | Completed | N/A | The Effects of Repetitive Transcranial Magnetic Stimulation in Patients With Alzheimer's Disease | September 1, 2016 | June 1, 2017 |
| NCT03101085 | Completed | Phase 1/Phase 2 | S-Equol in Alzheimer's Disease 2 Trial | May 5, 2017 | March 1, 2021 |
| NCT03721705 | Completed | Phase 3 | Renew NCP-5 for the Treatment of Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild Dementia of the Alzheimer's Type | November 12, 2018 | March 23, 2021 |
| NCT04903171 | Completed | N/A | Effects of Enriched Gardens in Nursing Home Residents With Dementia | March 15, 2020 | October 15, 2020 |
| NCT02819700 | Completed | Evaluation and Characterization of Behavioural Disorders and Dementias by the Behavioural Dysexecutive Syndrome Inventory (BDSI) | January 29, 2013 | January 28, 2018 | |
| NCT02361424 | Completed | Phase 2 | Pilot Study Assessing the Effects of PXT00864 in Patients With Mild Alzheimer Disease (AD) | February 2013 | June 2015 |
| NCT00018278 | Completed | Phase 4 | Electrophysiologic Measures of Treatment Response in Alzheimer Disease | October 1998 | September 2001 |
| NCT04052737 | Completed | Phase 2 | PMZ-1620 (Sovateltide) in Mild to Moderate Alzheimer's Disease | March 23, 2018 | January 6, 2023 |
| NCT03901092 | Completed | Phase 3 | A Reader Study to Assess Accuracy and Reliability of Flortaucipir F 18 Positron Emission Tomography (PET) Scan Interpretation | March 26, 2019 | April 26, 2019 |
| NCT00034762 | Completed | Phase 3 | Efficacy and Safety of Risperidone Compared With Placebo in the Treatment of Psychotic Symptoms in Patients With Alzheimer's Disease | December 2000 | January 2003 |
| NCT00000178 | Completed | Phase 3 | Multicenter Trial of Prednisone in Alzheimer's Disease | ||
| NCT00040378 | Completed | Prevention of Alzheimer's Disease by Vitamin E and Selenium (PREADVISE) | May 2002 | August 2016 | |
| NCT03847038 | Completed | N/A | BarcelonaBeta Dementia Prevention Research Clinic: a Study on Risk Factors Disclosure | July 16, 2018 | December 31, 2022 |
| NCT04640077 | Completed | Phase 2 | A Follow-On Study of Donanemab (LY3002813) With Video Assessments in Participants With Alzheimer's Disease (TRAILBLAZER-EXT) | November 23, 2020 | February 27, 2024 |
| NCT04200911 | Completed | Early Phase 1 | Cognition, Age, and RaPamycin Effectiveness - DownregulatIon of thE mTor Pathway | June 1, 2020 | January 13, 2022 |
| NCT03531684 | Completed | Phase 2 | Efficacy and Safety of MMFS in Early AD | March 20, 2018 | April 22, 2020 |
| NCT00216502 | Completed | Phase 3 | A Study of the Safety and Effectiveness of Galantamine in Patients With Alzheimer's Disease | August 2001 | November 2005 |
| NCT00479440 | Completed | Phase 1 | Study Evaluating the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of SAM-315 in Healthy Adults | August 2006 | March 2007 |
| NCT01334450 | Completed | Phase 2 | Transcranial Magnetic Stimulation (TMS) Treatment for Alzheimer Patients | June 2011 | June 2012 |
| NCT03883633 | Completed | Reversal of Cognitive Decline (ReCODE) Study | June 30, 2019 | December 31, 2020 | |
| NCT00750282 | Completed | Phase 2 | Phase II Study of Florbetaben (BAY 94-9172) PET Imaging for Detection/Exclusion of Cerebral β-amyloid in Patients With Probable Alzheimer's Disease Compared to Healthy Volunteers | August 2008 | November 2010 |
| NCT00838942 | Completed | Life From Vision in Alzheimer Disease | December 2004 | April 2011 | |
| NCT00479557 | Completed | Phase 2 | Study Evaluating Safety, Tolerability, And Immunogenicity Of ACC-001 In Subjects With Mild To Moderate Alzheimer's Disease | May 2007 | January 2013 |
| NCT04542109 | Completed | N/A | REmote Assessment and Dynamic Response Intervention | April 27, 2021 | June 17, 2022 |
| NCT05562583 | Completed | N/A | SAGE-LEAF: Reducing Burden in Alzheimer's Disease Caregivers Through Positive Emotion Regulation and Virtual Support | September 30, 2019 | April 30, 2022 |
| NCT05292222 | Completed | N/A | Transmagnetic Stimulation Pilot in Early Stage Alzheimer's Disease | June 17, 2022 | November 7, 2023 |
| NCT02249403 | Completed | Phase 2 | Efficacy and Safety of Talsaclidine in Patients With Mild to Moderate Dementia of Alzheimer Type | January 1999 | |
| NCT03744312 | Completed | Phase 1/Phase 2 | Imaging Inflammation in Alzheimer's Disease With 11C-ER176 | September 10, 2018 | July 20, 2022 |
| NCT03698760 | Completed | N/A | Computerized Olfactory Test - Alzheimer Disease Mild Stage | June 25, 2019 | March 5, 2020 |
| NCT00216593 | Completed | Phase 3 | Treatment of Severe Alzheimer's Disease: Evaluation of Efficacy and Safety of Galantamine Hydrobromide in a Controlled Study | December 2003 | March 2008 |
| NCT03612622 | Completed | N/A | Effect of Theta-Burst Transcranial Magnetic Stimulation (TBS) for Early Alzheimer's Disease | August 14, 2018 | December 30, 2020 |
| NCT00253123 | Completed | Phase 3 | A Study of the Effectiveness and Safety of Risperidone Versus Placebo in the Treatment of Behavioral Disturbances in Patients With Dementia | March 1997 | |
| NCT04149860 | Completed | Phase 1 | Study With Lu AF87908 in Healthy Participants and Participants With Alzheimer's Disease | September 27, 2019 | July 19, 2023 |
| NCT00831298 | Completed | N/A | Assessment of Sleep Disturbance in Alzheimer Disease | July 2010 | November 2011 |
| NCT02432222 | Completed | N/A | Effects of Visual Arts Training on Dementia | April 2015 | December 2015 |
| NCT04771845 | Completed | Transcranial Magnetic Stimulation in Mild Cognitive Impairment and Alzheimer Disease | May 1, 2008 | May 30, 2020 | |
| NCT00165659 | Completed | Phase 2 | A Multi-Center, Randomized, Double-Blind, Parallel Group Study With 3 Groups Receiving Placebo, 5 mg of E2020 and 10 mg of E2020 | November 2002 | |
| NCT04606251 | Completed | N/A | Home-Based Telerehabilitation for People With Alzheimer Disease | October 30, 2020 | April 15, 2021 |
| NCT03046121 | Completed | N/A | A Family-centered Intervention for Acutely-ill Persons With Dementia | November 6, 2017 | December 23, 2023 |
| NCT00788047 | Completed | Phase 1 | A Phase 1 Study To Evaluate The Effect Of Dimebon On The Pharmacokinetics Of Dextromethorphan | November 2008 | January 2009 |
| NCT06281314 | Completed | N/A | The Efficacy of VESPA 2.0 for Cognitive Rehabilitation in Patients With Mild Cognitive Impairment | March 1, 2021 | December 31, 2023 |
| NCT01565330 | Completed | Phase 1 | A Study of Two Doses of 18F-AV-45 in Alzheimer's Disease and Healthy Volunteers | March 2008 | August 2008 |
| NCT04330482 | Completed | N/A | Translating a Dementia Caregiver Intervention Into a Mobile Application | January 13, 2020 | May 30, 2022 |
| NCT03919669 | Completed | Phase 2 | A Longitudinal Evaluation of a Radiotracer for Use in Tau Tracking | April 2, 2019 | May 19, 2022 |
| NCT00745576 | Completed | Phase 1 | Study Evaluating The Potential Interaction Between Verapamil Immediate Release And SAM-531 When Co-Administered | October 2008 | December 2008 |
| NCT02333942 | Completed | Dementia Signal Development Study of Nautilus NeuroWave TM for the Detection of Dementia | May 2014 | February 2015 | |
| NCT00009191 | Completed | Phase 4 | The Depression in Alzheimer's Disease Study (DIADS) | November 2005 | November 2007 |
| NCT00178165 | Completed | N/A | Coordinating Center for Enhancing ADRD Caregiving | September 1996 | November 2001 |
| NCT00979316 | Completed | Phase 1 | Effect on the Electrocardiographic QT Interval Corrected for Heart Rate (QTc) in Healthy Subjects | September 2009 | February 2010 |
| NCT03221894 | Completed | A Retrospective Study to Investigate the Additive Effectiveness of Chinese Herbal Medicine in Alzheimer's Disease | July 15, 2017 | July 31, 2021 | |
| NCT03611439 | Completed | N/A | Effects of an 8 Component Botanical Supplement on Mild and Moderate Alzheimer's Patients | October 1, 2013 | December 25, 2015 |
| NCT04720001 | Completed | Florbetaben PET Imaging in PPA | August 23, 2018 | February 26, 2021 | |
| NCT05821153 | Completed | Phase 1 | Low Dose IL2 Immunotherapy in AD | June 19, 2019 | April 27, 2022 |
| NCT03489044 | Completed | Phase 2 | An Investigation of Levetiracetam in Alzheimer's Disease | October 28, 2018 | March 21, 2022 |
| NCT02968719 | Completed | Phase 1 | A Phase 1, Corplex™ Donepezil Transdermal System Compared to Oral Aricept® | November 2016 | July 11, 2017 |
| NCT03363269 | Completed | Phase 2 | Evaluate the Efficacy and Safety of ID1201 for Dose-finding in Mild Alzheimer's Disease | April 12, 2016 | April 17, 2019 |
| NCT01089582 | Completed | Quality Of Life Assessment In Alzheimer's Disease (AD) Patients Receiving Aricept Tablets | November 2007 | July 2009 | |
| NCT03073876 | Completed | Phase 4 | Detecting an Early Response to Donepezil With Measures of Visual Attention | December 1, 2005 | January 13, 2021 |
| NCT04474405 | Completed | Early Phase 1 | Exploratory Evaluation of Flortaucipir Injection in Healthy Volunteers and Cognitively Impaired Subjects | August 16, 2013 | December 9, 2013 |
| NCT03643003 | Completed | N/A | Music Therapy for Persons With Dementia | May 25, 2018 | September 30, 2018 |
| NCT03784300 | Completed | Phase 1 | A Safety Study of PTI-125 in Healthy Volunteers | August 18, 2017 | March 27, 2018 |
| NCT01487395 | Completed | Phase 1 | Prediction of Cognitive Properties of New Drug Candidates for Neurodegenerative Diseases in Early Clinical Development | December 2011 | December 2013 |
| NCT00110552 | Completed | Phase 1 | Effects of Sage on Memory and Mental Performance in Alzheimer's Disease Patients | July 2005 | October 2014 |
| NCT04117178 | Completed | Phase 4 | Monitoring Anti-Dementia Drugs by Serum Levels | February 4, 2020 | February 16, 2023 |
| NCT00249145 | Completed | Phase 3 | A Study of the Effectiveness and Safety of Risperidone in the Treatment of Behavioral Disturbances in Patients With Dementia | April 1995 | December 1996 |
| NCT03522129 | Completed | Phase 1 | Study to Evaluate the Effect of CT1812 Treatment on Amyloid Beta Oligomer Displacement Into CSF in Subjects With Mild to Moderate Alzheimer's Disease | May 30, 2018 | February 6, 2019 |
| NCT00956410 | Completed | Phase 2 | To Investigate the Safety and Tolerability of Repeated Subcutaneous Injections of CAD106 in Alzheimer's Patients | September 2009 | June 2011 |
| NCT05538455 | Completed | N/A | Investigating ProCare4Life Impact on Quality of Life of Elderly Subjects With Neurodegenerative Diseases | September 30, 2022 | April 30, 2023 |
| NCT03550131 | Completed | N/A | Innovations in Dementia Empowerment and Action | December 5, 2018 | May 16, 2023 |
| NCT00479700 | Completed | Phase 1 | Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAM-531 in Healthy Subjects | May 2006 | July 2006 |
| NCT00285025 | Completed | Phase 2 | Study of the Effect of SR57667B in Patients With Alzheimer's Disease | March 2005 | September 2005 |
| NCT06179979 | Completed | PET Study With 11 C-PIB to Evaluate Amyloid Protein Deposits in Mild Cognitive Disorder, Alzheimer's Disease and Early Frontotemporal Degeneration. | May 17, 2008 | July 15, 2008 | |
| NCT04585347 | Completed | Phase 1 | Single Dose Study of ALZ-801 Prototype Tablets | September 16, 2015 | November 13, 2015 |
| NCT01002079 | Completed | Phase 1 | Drug-Drug Interaction Study With Rifampin | August 2010 | October 2010 |
| NCT03978052 | Completed | N/A | Prevention of Cognitive Decline in ApoE4 Carriers With Subjective Cognitive Decline After EGCG and a Multimodal Intervention | October 30, 2019 | June 28, 2023 |
| NCT03863041 | Completed | N/A | Study of Phosphorylated Metabolism Profile as Predictive Biomarker of Cognitive Decline in Memory Complaint. | April 8, 2019 | June 15, 2023 |
| NCT03706261 | Completed | Phase 1 | Alzheimer's PET Imaging in Racially/Ethnically Diverse Adults | March 22, 2019 | July 14, 2023 |
| NCT00452504 | Completed | Phase 1 | Single Ascending Dose Study of SRA-444 in Healthy Subjects | February 2007 | June 2007 |
| NCT01515982 | Completed | N/A | Physical Exercise as an Additional Treatment for Alzheimer Disease | February 2010 | December 2013 |
| NCT02946710 | Completed | P75NTR, Diagnostic Biomarker for Alzheimer's Disease: Quantification Study in Cerebrospinal Fluid | December 2014 | December 2017 | |
| NCT05602220 | Completed | N/A | Heartrate and Breathing Effects on Attention and Memory 1 | January 11, 2023 | November 13, 2023 |
| NCT05514756 | Completed | N/A | VINCI-AD: An Investigation of Transcutaneous Vagus Nerve Stimulation in Mild Cognitive Impairment. | June 1, 2022 | June 30, 2023 |
| NCT05697354 | Completed | N/A | New Virtual Reality Technologies and Telemedicine for Cognitive Rehabilitation in Alzheimer's Disease | August 30, 2021 | December 21, 2021 |
| NCT03435861 | Completed | Phase 2 | Effect of Neflamapimod on Brain Inflammation in Alzheimer's Disease Patients | October 8, 2018 | June 30, 2021 |
| NCT04557592 | Completed | Comparisons of gaIt aNalyses pERformance Between the Gaitrite walkwaYs | June 17, 2019 | February 26, 2020 | |
| NCT04079803 | Completed | Phase 2 | PTI-125 for Mild-to-moderate Alzheimer's Disease Patients | September 9, 2019 | March 31, 2020 |
| NCT01743534 | Completed | Conservation of Praxis in the Food and Alzheimer Disease | July 2011 | July 2016 | |
| NCT00486044 | Completed | Phase 2 | Evaluating Simvastatin's Potential Role in Therapy | February 2005 | June 2009 |
| NCT02409030 | Completed | Multi-parameter Diagnostic Blood Test for the Diagnosis of Alzheimer's Disease | January 2014 | October 18, 2017 | |
| NCT01384344 | Completed | N/A | Ecological Assessment of Apathy in Alzheimer's Disease and in Control Subjects: Video Recognition and Actigraphy | June 2011 | June 2012 |
| NCT04587583 | Completed | Phase 1/Phase 2 | WeCareAdvisor: A Web-Based Tool to Improve Quality of Life for Military Veterans With Dementia and Their Caregivers | October 19, 2020 | October 21, 2021 |
| NCT03030105 | Completed | Phase 1 | Study to Evaluate the Effects of BPN14770 on Scopolamine-induced Cognitive Impairment in Healthy Volunteers | January 2017 | June 2017 |
| NCT03690193 | Completed | N/A | Feasibility and Efficacy of the Ketogenic Diet in Alzheimer's Disease | December 3, 2013 | January 6, 2017 |
| NCT01608061 | Completed | N/A | ADvance DBS-f in Patients With Mild Probable Alzheimer's Disease | May 2012 | September 2018 |
| NCT02719938 | Completed | N/A | Triggered Palliative Care for Advanced Dementia | March 2016 | October 31, 2017 |
| NCT03290326 | Completed | N/A | tACS for Amyloid-β Reduction in Alzheimer's Disease | November 27, 2017 | May 14, 2019 |
| NCT00432081 | Completed | Phase 3 | Effect of Indomethacin on the Progression of Alzheimer's Disease | May 2000 | August 2005 |
| NCT03902548 | Completed | Phase 1 | Initial Investigation of [18F]P16-129 in Alzheimer's Disease Patients and Healthy Volunteers | February 21, 2018 | November 2, 2019 |
| NCT00177489 | Completed | N/A | Coordinating Center for Caregiver Intervention Trial | June 2002 | September 2005 |
| NCT00733863 | Completed | Phase 2 | Safety and Tolerability of Repeated Subcutaneous Injections of CAD106 in Mild Alzheimer's Patients. | July 2008 | |
| NCT02702817 | Completed | Phase 2 | Randomized Trial of Low-dose Naproxen in Cognitively Intact Persons at Risk of Alzheimer's Dementia | August 1, 2012 | July 15, 2017 |
| NCT04157712 | Completed | Phase 1 | Multiple Ascending Dose Study of ALZ-801 | September 26, 2015 | July 4, 2016 |
| NCT00065767 | Completed | Phase 2/Phase 3 | Cognitive and Neurophysiological Effects of Raloxifene in Alzheimer's Disease | September 2001 | March 2005 |
| NCT04489303 | Completed | Phase 2 | Virtual Patient Behavioral Response Training for Family Caregivers | May 15, 2020 | May 30, 2021 |
| NCT06390098 | Completed | Phase 1 | Positron Emission Tomography Study in Healthy Subjects to Determine the Relationship Between Plasma Concentration and Brain Target Occupancy of ASN51 | August 9, 2021 | November 2, 2021 |
| NCT03467477 | Completed | Phase 2 | Tau Screening Study in Subjects With Early Symptomatic AD | March 8, 2018 | November 15, 2018 |
| NCT01409694 | Completed | Phase 3 | Alzheimer's Disease - Input of Vitamin D With mEmantine Assay | September 2011 | January 2016 |
| NCT03367403 | Completed | Phase 2 | A Study of LY3002813 in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ) | December 18, 2017 | September 21, 2021 |
| NCT04538066 | Completed | Phase 2 | Bryostatin Treatment of Moderately Severe Alzheimer's Disease | August 30, 2020 | November 16, 2022 |
| NCT04287738 | Completed | N/A | Care Ecosystem: Navigating Patients and Families Through Stages of Care, Extension Trial | March 20, 2015 | May 20, 2022 |
| NCT05077826 | Completed | N/A | Enhancing Memory in Mild Cognitive Impairment and Early Stage Alzheimer's Disease | October 7, 2021 | April 30, 2023 |
| NCT00083590 | Completed | Phase 2 | Huperzine A in Alzheimer's Disease | April 2004 | November 2007 |
| NCT01696019 | Completed | N/A | Randomized Trial of Exercise and Social Interaction in a Community-Based Sample of Non-Demented Chinese Elders | July 2008 | September 2009 |
| NCT04277104 | Completed | N/A | Does Acoustic Stimulation During Sleep Boost Slow Wave Sleep and Memory Performance? | October 20, 2019 | July 20, 2023 |
| NCT02323334 | Completed | Phase 1 | A Study of LY3202626 in Healthy Participants and Participants With Alzheimer's Disease | December 2014 | February 2016 |
| NCT00104013 | Completed | Phase 3 | Study of Xaliproden (SR57746A) in Patients With Mild-to-Moderate Dementia of the Alzheimer's Type | November 2003 | November 2007 |
| NCT02854917 | Completed | Memantine and Comprehensive, Individualized, Patient Centered Management of Alzheimer's Disease: Health Outcome | July 2016 | January 5, 2018 | |
| NCT01565291 | Completed | Early Phase 1 | A Preliminary Study of 18F-AV-45 in Alzheimer's Disease and Healthy Elderly Volunteers | June 2007 | January 2008 |
| NCT02978729 | Completed | N/A | Telephone Versus Videoconference Communication for Remote Genetic Disclosure in the APOE4 Trial | August 2016 | July 11, 2019 |
| NCT04745104 | Completed | Phase 1 | A Trial of SHR-1707 in Healthy Young Adult and Elderly Subjects | February 23, 2021 | March 21, 2022 |
| NCT00506415 | Completed | Phase 3 | Comparative Efficacy, Safety, and Tolerability of Rivastigmine 10 and 15 cm^2 Patch in Patients With Alzheimer's Disease (AD) Showing Cognitive Decline | June 2007 | May 2011 |
| NCT05094817 | Completed | Feasibility of an Online, Self-administered Cognitive Screening Tool in Older Patients Undergoing Ambulatory Surgery | February 11, 2022 | July 21, 2023 | |
| NCT04165213 | Completed | N/A | Care of Persons With Dementia in Their Environments (COPE) in Programs of All-Inclusive Care of the Elderly (PACE) | June 28, 2021 | May 31, 2024 |
| NCT00568776 | Completed | Phase 2 | ELND005 in Patients With Mild to Moderate Alzheimer's Disease | December 2007 | May 2010 |
| NCT02817074 | Completed | N/A | MIND Diet Intervention and Cognitive Decline | January 2017 | June 30, 2021 |
| NCT02353598 | Completed | Phase 1 | A Study of Crenezumab in Participants With Mild to Moderate Alzheimer Disease | February 26, 2015 | March 26, 2019 |
| NCT02955706 | Completed | Phase 4 | Assessment the Efficacy of Acetyl-L-carnitine in Patient With Alzheimer's Disease | April 1, 2016 | January 25, 2019 |
| NCT01646723 | Completed | N/A | Volunteers Adding Life in Dementia | June 2012 | March 2016 |
| NCT05317910 | Completed | N/A | Effect of Music Therapy on Anxiety of Caregivers of Alzheimer's Disease Patients | April 1, 2022 | July 20, 2022 |
| NCT02055092 | Completed | Young Onset Dementia - the Difficult Diagnosis and the Stressful Life for the Whole Family | February 2014 | July 2020 | |
| NCT03790709 | Completed | Phase 2/Phase 3 | ANAVEX2-73 for Treatment of Early Alzheimer's Disease | July 3, 2018 | June 30, 2022 |
| NCT03899844 | Completed | Study to Evaluate Amyloid in Blood and Imaging Related to Dementia | April 9, 2019 | January 31, 2024 | |
| NCT05422339 | Completed | N/A | Efficacy of Gamification in Enhancing User Engagement | September 12, 2022 | September 28, 2023 |
| NCT01550549 | Completed | N/A | Evaluation of Web-based Training to Educate Physicians in the Methods of Interpreting Florbetapir-PET Scans | August 2011 | September 2011 |
| NCT00000171 | Completed | Phase 3 | Study of Melatonin: Sleep Problems in Alzheimer's Disease | ||
| NCT01273272 | Completed | Phase 2 | Cognitive-Behavioral Treatment for Mild Alzheimer's Patients and Their Caregivers | February 2011 | September 2017 |
| NCT03545789 | Completed | Phase 1 | Phase 1 Test-retest Evaluation of [18F]MNI-958 PET | March 12, 2018 | February 6, 2020 |
| NCT03351452 | Completed | N/A | tES Effects on Associative Memory Performance | April 9, 2018 | February 24, 2020 |
| NCT00795730 | Completed | Phase 1 | Multiple Dose Study Evaluating the Safety and Tolerability of NSA-789 | January 2009 | May 2009 |
| NCT03412604 | Completed | N/A | Effect of Modulating Gamma Oscillations Using tACS | August 2, 2018 | September 15, 2019 |
| NCT00880555 | Completed | Semantic Memory, Financial Capacity, and Brain Perfusion in Mild Cognitive Impairment (MCI) (CASL) | April 2009 | May 2014 | |
| NCT03053908 | Completed | N/A | Orexin and Tau Pathology in Cognitively Normal Elderly | March 27, 2018 | May 13, 2019 |
| NCT04157244 | Completed | N/A | The Music, Sleep and Dementia Study | March 12, 2019 | January 12, 2021 |
| NCT05202197 | Completed | Smart Cupboard-based System for Memory Assessment in Alzheimer's Patients | October 30, 2021 | November 20, 2021 | |
| NCT04559828 | Completed | N/A | Attenuation of Inflammatory Processes Associated With Alzheimer's Disease After Consumption of Pomace Olive Oil. | June 10, 2020 | July 28, 2021 |
| NCT03475316 | Completed | N/A | Movement Intervention for Memory Enhancement | March 28, 2019 | June 30, 2020 |
| NCT06151795 | Completed | Phase 1 | A Study to Evaluate XTR006 in Chinese Volunteers | June 12, 2023 | January 10, 2024 |
| NCT05916664 | Completed | N/A | Efficacy Study of Kinto Care Coaching for Dementia Family Caregivers | May 18, 2023 | April 22, 2024 |
| NCT00658125 | Completed | N/A | Deep Brain Stimulation (DBS) for Alzheimer's Disease | March 1, 2007 | June 30, 2010 |
| NCT04299308 | Completed | N/A | Acute Exercise and the Cerebral Metabolic Response in Aging and Alzheimer's Disease | August 28, 2020 | October 31, 2023 |
| NCT04574921 | Completed | N/A | Study on Safety, Feasibility and Neural Activation of Non-Invasive Light Therapy System | October 1, 2020 | July 12, 2022 |
| NCT04735536 | Completed | Phase 2 | Pilot Clinical Study of CT1812 in Mild to Moderate Alzheimer's Disease Using EEG | July 9, 2020 | April 26, 2023 |
| NCT04981587 | Completed | N/A | Effects of Strength Exercise on Fall Risk in Elderly With Alzheimer's Disease | May 1, 2021 | March 4, 2022 |
| NCT03981159 | Completed | N/A | Effect of Exercise Training in Alzheimer's Patients | March 1, 2017 | November 15, 2017 |
| NCT02221622 | Completed | Phase 1 | Allopregnanolone for Mild Cognitive Impairment Due to Alzheimer's Disease or Mild AD | August 2014 | February 2018 |
| NCT00403507 | Completed | Phase 2 | Exercise Treatment of Mild-Stage Probable Alzheimer's Disease | October 2006 | October 2009 |
| NCT03654911 | Completed | Sustainable Method for Alzheimer's Prediction | April 11, 2018 | January 31, 2020 | |
| NCT00036114 | Completed | Phase 3 | Study of Aripiprazole in the Treatment of Patients With Psychosis Associated With Dementia of the Alzheimer's Type | March 2000 | August 2003 |
| NCT00277810 | Completed | Phase 2/Phase 3 | Study Evaluating the Safety, Tolerability, and Efficacy of Lecozotan SR in Outpatients With Alzheimer's Disease | March 2006 | June 2008 |
| NCT05055310 | Completed | The Mechanism of MicroRNAs Network in Alzheimer's Disease | October 2016 | December 31, 2019 | |
| NCT00677885 | Completed | P-glycoprotein Function in Brain Diseases | May 9, 2008 | August 25, 2014 | |
| NCT00053599 | Completed | Phase 3 | Cholesterol Lowering Agent to Slow Progression (CLASP) of Alzheimer's Disease Study | December 2002 | October 2007 |
| NCT01823666 | Completed | Predicting the Conversion From Mild Cognitive Impairment to Dementia | September 2012 | September 2014 | |
| NCT00906191 | Completed | Phase 1 | Study Evaluating How Quickly And To What Extent The 14-Carbon-SAM-531 Is Absorbed/Converted/Eliminated In Male Subjects | May 2009 | August 2009 |
| NCT01696123 | Completed | Phase 2 | Efficacy and Tolerability of MLC601 in Patients With Mild to Moderate Alzheimer Disease Who Were Unable to Tolerate or Failed to Benefit From Treatment With Rivastigmine | January 2011 | August 2012 |
| NCT04496778 | Completed | N/A | Low Level Laser Therapy Impact on Cognitive Function and Quality of Life in Alzheimer Anemic Elderly Patients | January 3, 2020 | August 1, 2020 |
| NCT03402503 | Completed | Phase 2 | Safety, and Efficacy of a New Buccal Film of Montelukast in Patients With Mild to Moderate Alzheimer's Disease | November 26, 2018 | April 3, 2024 |
| NCT04856072 | Completed | N/A | Deep Brain Stimulation in Alzheimer's Disease: Biomarkers and Dose Optimization | December 19, 2014 | December 5, 2023 |
| NCT04279418 | Completed | N/A | Non-pharmacological Intervention for Preclinical Alzheimer's Disease | April 1, 2019 | December 31, 2019 |
| NCT04567745 | Completed | Phase 1 | Automated Retinal Image Analysis System (EyeQuant) for Computation of Vascular Biomarkers | September 29, 2020 | September 30, 2021 |
| NCT00007189 | Completed | Phase 3 | Alzheimer's Disease Anti-Inflammatory Prevention Trial (ADAPT) | January 2001 | |
| NCT00479297 | Completed | Phase 1 | Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAM-531 in Healthy Japanese Males | May 2006 | February 2007 |
| NCT04491006 | Completed | Phase 2 | A Study of ATH-1017 in Mild to Moderate Alzheimer's Disease | November 23, 2020 | May 20, 2022 |
| NCT03239561 | Completed | Early Phase 1 | Evaluation of Tau Protein in the Brain of Participants With Alzheimer's Disease Compared to Healthy Participants | September 6, 2017 | April 30, 2018 |
| NCT01565434 | Completed | N/A | Erythrocyte Complement Receptor 1 and Alzheimer Disease | February 2012 | April 2015 |
| NCT02253732 | Completed | N/A | Skeletal Muscle as a Mediator of Exercise Induced Effects on Metabolism & Cognitive Function: Role for Myokines & miRNAs | September 2015 | March 2018 |
| NCT05984732 | Completed | N/A | Intergenerational Reminiscence and Digital Storytelling | April 15, 2021 | August 30, 2022 |
| NCT03402659 | Completed | Phase 2 | Proof-of-Concept Study of a Selective p38 MAPK Alpha Inhibitor, Neflamapimod, in Subjects With Mild Alzheimer's Disease | December 29, 2017 | July 31, 2019 |
| NCT03543878 | Completed | N/A | Stimulating Neural Activity to Improve Blood Flow and Reduce Amyloid: Path to Clinical Trials | November 16, 2018 | February 10, 2020 |
| NCT04948450 | Completed | N/A | A Multidomain Intervention Program for Older People With Dementia | November 24, 2022 | January 31, 2024 |
| NCT00105547 | Completed | Phase 3 | Efficacy Study of MPC-7869 to Treat Patients With Alzheimer's | February 2005 | May 2008 |
| NCT04672135 | Completed | Phase 1 | A Phase 1 (First in Human) Randomized, Double-blind, Placebo-controlled SAD, MAD Study With Oral REM0046127 | November 9, 2020 | April 26, 2022 |
| NCT00161473 | Completed | N/A | Alzheimer's in Long-Term Care--Treatment for Agitation | January 2001 | September 2009 |
| NCT00718731 | Completed | Phase 1 | Study GSI-136 in Healthy Young and Healthy Elderly Subjects | March 2008 | August 2008 |
| NCT06151808 | Completed | N/A | Analysis of XTR006 PET Imaging in Non-cognitively Impaired Subjects, MCI Due toAD, and Mild to Moderate AD Subjects | September 1, 2022 | January 10, 2024 |
| NCT03720548 | Completed | Phase 1 | A Study of LY3372993 in Healthy Participants and Participants With Alzheimer's Disease (AD) | November 5, 2018 | May 14, 2019 |
| NCT00443014 | Completed | Phase 4 | The Dementia Study in Northern Norway | June 2003 | June 2009 |
| NCT05807100 | Completed | Investigation of Alzheimer's Disease and Periodontal Status | March 2, 2022 | January 6, 2023 | |
| NCT02770482 | Completed | N/A | Amyloid Beta-peptide 1-40 and Alzheimer's Disease | June 2014 | March 14, 2018 |
| NCT04939818 | Completed | Clinical Feasibility of Speech Phenotyping for Remote Assessment of Neurodegenerative and Psychiatric Disorders | June 14, 2021 | September 15, 2022 | |
| NCT04388254 | Completed | Phase 2 | Simufilam (PTI-125), 100 mg, for Mild-to-moderate Alzheimer's Disease Patients | March 24, 2020 | November 9, 2023 |
| NCT03461276 | Completed | Phase 2 | Safety and Immunogenicity of Repeated Doses of ABvac40 in Patients With a-MCI or Vm-AD | December 13, 2017 | March 23, 2023 |
| NCT06019117 | Completed | N/A | Effectiveness of Probiotic K10 in Managing Health Outcomes in Parkinson and Alzheimer Disease | August 10, 2023 | January 7, 2024 |
| NCT05147428 | Completed | N/A | A Program to Reduce Inappropriate Medications Among Older Adults With Alzheimer's Disease | June 21, 2022 | October 1, 2023 |
| NCT02294513 | Completed | Hearing Instruments in Alzheimer's Disease | October 2014 | February 2017 | |
| NCT02915939 | Completed | N/A | The Residential Care Transition Module | December 2016 | August 30, 2021 |
| NCT02271685 | Completed | N/A | Sound Estimation and Accuracy Task | February 2015 | May 2015 |
| NCT04563767 | Completed | Feasibility - Infinitome | September 15, 2020 | October 13, 2020 | |
| NCT05862935 | Completed | N/A | Influence of Physical Exercise as Adjuvant Treatment in Patients With Alzheimer's Disease | June 1, 2022 | February 1, 2023 |
| NCT01582919 | Completed | N/A | Neuroimaging Markers of Alzheimer Disease: a Longitudinal Population Study | September 2012 | June 2015 |
| NCT06435078 | Completed | N/A | Developments of Novel Virtual Visual and Haptic Stimulation Systems for the Elderly | March 6, 2017 | August 21, 2017 |
| NCT02392468 | Completed | Phase 1 | Study of Systemic and Ocular Safety and Pharmacokinetics of BI 409306 in Patients With Schizophrenia, Alzheimer's Disease, and Healthy Volunteers | April 15, 2015 | August 10, 2017 |
| NCT05501119 | Completed | N/A | SUPPORT-D Intervention for Persons With Alzheimer's Disease and Their Caregivers | January 27, 2023 | April 1, 2024 |
| NCT00726115 | Completed | Phase 1 | Study Evaluating Safety, Tolerability and Pharmacokinetics of Single and Multiple Dose of SAM-531 | August 2008 | February 2009 |
| NCT02351453 | Completed | Patients With Alzheimer Disease, Spouse Carers and Risk of Institutionalization: a Prospective Observational Cohort Study of Dyads (AID Study) | August 2011 | February 2013 | |
| NCT03587649 | Completed | Phase 1 | Evaluation of [18F]MNI-1126 as an Imaging Marker for Synaptic Density Loss | May 7, 2018 | February 26, 2020 |
| NCT04251182 | Completed | Phase 2 | Clinical Study Evaluating Efficacy and Safety of T3D-959 in Mild-to-moderate AD Subjects | March 1, 2021 | February 17, 2023 |
| NCT04759092 | Completed | N/A | A Four Month Home Based tDCS Study on Patients With Alzheimer's Disease. | April 1, 2019 | May 1, 2021 |
| NCT05218018 | Completed | N/A | Triglyceride Effects on Blood Flow in the Human Brain | March 1, 2020 | January 13, 2022 |
| NCT03665909 | Completed | N/A | A Proactive Health Monitoring Intervention for Dementia Caregivers | April 1, 2014 | April 8, 2020 |
| NCT03455569 | Completed | N/A | A Dyadic Sleep Intervention for Alzheimer's Disease Patients and Their Caregivers | September 11, 2018 | February 1, 2023 |
| NCT00018382 | Completed | Phase 2 | Insulin, Neurogenetics and Memory in Alzheimer's Disease | October 1999 | March 2003 |
| NCT00551161 | Completed | Phase 4 | Magnetic Resonance Spectroscopy Study of Memantine in Alzheimer's Disease | August 2007 | December 2011 |
| NCT00982202 | Completed | Phase 2 | Pioglitazone in Alzheimer Disease | January 2002 | January 2005 |
| NCT02240693 | Completed | Phase 2 | Alzheimer Disease Proof of Concept Study With BI 409306 Versus Placebo | January 15, 2015 | October 9, 2017 |
| NCT05784298 | Completed | N/A | Acute Effect of Low-intensity Gamma rTMS on Cognitive and EEG Parameters in Adults With Mild Dementia by Alzheimer's Disease | April 28, 2022 | September 28, 2023 |
| NCT04805983 | Completed | Phase 1 | Evaluating the Safety, Tolerability, Pharmacokinetics and Receptor Occupancy of BMS-984923 | March 25, 2021 | April 24, 2022 |
| NCT02351882 | Completed | Phase 2/Phase 3 | Safety and Efficacy of Nabilone in Alzheimer's Disease | January 2015 | March 2019 |
| NCT05475158 | Completed | Comparison of OCTA Factors in Patients With or Without Amyloid Pathology: A Prospective Study | September 1, 2019 | July 31, 2021 | |
| NCT04797715 | Completed | Phase 3 | Assessing Clinical Outcomes in Alzheimer's Disease Agitation | December 31, 2020 | November 21, 2022 |
| NCT01168245 | Completed | Phase 1 | TMS Stimulation and Cognitive Training in Alzheimer Patients | January 2010 | September 2011 |
| NCT00208819 | Completed | Phase 4 | A Comparison of Two Standard Therapies in the Management of Dementia With Agitation | September 2003 | July 2007 |
| NCT04555616 | Completed | N/A | Environmental Design for Behavioral Regulation in People With Dementia | January 25, 2021 | October 13, 2021 |
| NCT00253201 | Completed | Phase 3 | A Study of the Safety and Effectiveness of Two Doses of Galantamine Versus Placebo in the Treatment of Patients With Alzheimer's Disease | October 1997 | |
| NCT05172128 | Completed | N/A | Effect of Blueberry Supplementation on Alzheimer's Biomarkers | February 21, 2022 | February 6, 2023 |
| NCT02697721 | Completed | N/A | Powerful Tools for Caregivers of Dementia Patients | February 2016 | February 2019 |
| NCT00151398 | Completed | Phase 2 | Study Evaluating Lecozotan SR in Mild to Moderate Alzheimer's Disease (AD) | October 6, 2005 | March 15, 2008 |
| NCT03834402 | Completed | INTERCEPTOR Project: From MCI to Dementia | May 1, 2019 | December 31, 2023 | |
| NCT04206670 | Completed | N/A | In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment | March 10, 2020 | December 8, 2021 |
| NCT04919005 | Completed | N/A | Virtual Environment to Aid Cognitive Stimulation of Elderly People With Early Alzheimer's | July 1, 2016 | July 20, 2017 |
| NCT01461109 | Completed | Phase 1 | Research Involving Subjects With Parkinson's Disease, Alzheimer Disease and Healthy Controls | August 2011 | May 2014 |
| NCT06354933 | Completed | Neurological Soft Signs in Neurodegenerative Dementias | April 1, 2022 | February 1, 2024 | |
| NCT03943264 | Completed | Phase 1 | A Biomarker-directed Study of XPro1595 in Patients With Alzheimer's | November 20, 2019 | September 1, 2021 |
| NCT00397891 | Completed | Phase 1 | Study Evaluating Single Ascending Doses of AAB-001 Vaccine SAD Japanese Patients With Alzheimers Disease | October 2006 | February 2010 |
| NCT04571697 | Completed | A Study of Comparing Rates of Dementia and Alzheimer's Disease in Participants Initiating Methotrexate Versus Those Initiating Anti-tumor Necrosis Factor (TNF)-Alpha Therapy | September 28, 2020 | October 27, 2020 | |
| NCT00494962 | Completed | Phase 1 | Study Comparing Lecozotan SR Two 5-mg Tablets Vs. Lecozotan SR One 10-mg Tablet in Healthy Subjects | June 2007 | June 2007 |
| NCT03299062 | Completed | N/A | Smell, Voice and Nasal Swabs as Markers for Neuro-degenerative Disorders | November 14, 2017 | December 21, 2021 |
| NCT03635047 | Completed | Phase 1 | A Phase I Study for Safety and Tolerability of AL002. | November 12, 2018 | November 25, 2020 |
| NCT03846232 | Completed | Detection of Cerebral Proteinopathy in Alzheimer's Disease Through Magnetic Resonance Imaging | February 12, 2019 | December 31, 2022 | |
| NCT05715866 | Completed | N/A | Non-invasive Stimulation Through Nesa and Therapeutic Exercise on Sleep Disturbances on Alzheimer's Disease Patients. | December 7, 2021 | August 22, 2022 |
| NCT03019536 | Completed | Phase 1 | A Study of LY3303560 in Participants With Mild Cognitive Impairment or Alzheimer's Disease | January 31, 2017 | June 5, 2019 |
| NCT03929302 | Completed | N/A | Brain Energy Metabolism and Sleep in Adults | November 30, 2018 | July 31, 2022 |
| NCT05787041 | Completed | Phase 1 | The Effect of High Fat Diet on the Pharmacokinetics of AD16 Tablets in Healthy Chinese Adult Subjects | June 14, 2019 | December 14, 2019 |
| NCT01094145 | Completed | N/A | Deep Brain Stimulation (DBS) of the Nucleus Basalis Meynert (NBM) to Treat Cognitive Deficits in Light to Moderate Alzheimer's Disease | January 2010 | January 2013 |
| NCT04480112 | Completed | N/A | Impact of Covid-19 on Frequent Social Interaction Through Communication Technologies in the Cognitive Status of Socially-isolated Older Adults | June 2, 2020 | June 11, 2021 |
| NCT01564706 | Completed | Phase 1 | A Study of 18F-AV-45 in Healthy Volunteers | October 2007 | January 2008 |
| NCT03080051 | Completed | Early Phase 1 | Evaluation of [18F]MNI-952 as a Potential PET Radioligand for Imaging Tau Protein in the Brain | August 2016 | March 6, 2017 |
| NCT04570644 | Completed | Phase 1 | Randomized I/II Phase Study of ALZT-OP1 Combination Therapy in Alzheimer's Disease and Normal Healthy Volunteers | August 28, 2020 | January 18, 2021 |
| NCT00024531 | Completed | Phase 2 | Lipitor as a Treatment for Alzheimer's Disease | October 2000 | August 2004 |
| NCT05628636 | Completed | Phase 1 | AC-OLE-01-VA Tolerability Study in Healthy Participants Under Different Dosing Conditions | November 14, 2022 | April 3, 2023 |
| NCT03666624 | Completed | N/A | Socially Isolated Older Adults Living With Dementia | August 6, 2020 | December 30, 2020 |
| NCT02530255 | Completed | N/A | Telomerase Activator and Retinal Amyloid | December 1, 2016 | December 31, 2018 |
| NCT00153010 | Completed | Phase 2 | An Evaluation of Three Doses of NS 2330 in Patients With Mild to Moderate Dementia of the Alzheimer's Type | February 2003 | |
| NCT00029120 | Completed | Evaluation of Age- and Alzheimer's Disease-Related Memory Disorder | December 18, 2001 | April 21, 2008 | |
| NCT03542656 | Completed | Phase 3 | Application of Amyloid PET in Cerebral Amyloid Angiopathy | September 11, 2014 | March 22, 2018 |
| NCT03408041 | Completed | Reported Time Between Onset and Diagnosis of Alzheimer's Disease: Correlation With Objective Parameters | May 1, 2016 | October 1, 2017 | |
| NCT02843529 | Completed | N/A | Evaluation of a Computerized Complex Instrumental Activities of Daily Living Marker (NMI) | October 17, 2016 | February 21, 2020 |
| NCT00004845 | Completed | Phase 2/Phase 3 | A Multicenter Trial of Rofecoxib and Naproxen in Alzheimer's Disease (NSAID Study) | December 2001 | |
| NCT01122329 | Completed | Phase 4 | A Positron Emission Tomography (PET) Study Evaluating Brain Metabolism of a Medical Food in Alzheimer's Disease | October 2010 | January 2015 |
| NCT04074837 | Completed | Phase 1 | Phase1a, Dose-escalation Study of NNI-362 in Healthy Aged Volunteers | August 1, 2019 | August 15, 2021 |
| NCT05891938 | Completed | N/A | Effects of Hydrogen Gas Inhalation on Adults of Various Ages | January 1, 2023 | April 5, 2023 |
| NCT04928976 | Completed | Amyloid Prediction in Early Stage Alzheimer's Disease Through Speech Phenotyping | January 22, 2021 | July 30, 2021 | |
| NCT05477056 | Completed | Quality Improvement PrecivityAD Clinician Survey (QUIP I) | March 1, 2021 | October 6, 2022 | |
| NCT00911807 | Completed | Phase 2 | Comparative Study to Test Safety and Efficacy of Neurotrophic and Cholinergic Treatment of Alzheimer's Disease | October 2004 | April 2008 |
| NCT03520998 | Completed | Phase 2 | A Randomized Study to Assess the Safety of GRF6019 Infusions in Subjects With Mild to Moderate Alzheimer's Disease | April 16, 2018 | May 24, 2019 |
| NCT03076671 | Completed | N/A | More Than a Movement Disorder: Applying Palliative Care to Parkinson's Disease | March 1, 2017 | December 31, 2020 |
| NCT02978768 | Completed | N/A | Tai Chi 6-Form Sports Apparatus With Alzheimer's Disease | August 2011 | June 2015 |
| NCT05077501 | Completed | Phase 1 | Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Doses of ACD856 | September 29, 2021 | May 23, 2022 |
| NCT04956874 | Completed | N/A | FL-REACH: Pilot Trial of a Brief Dementia Caregiver Intervention | October 4, 2019 | September 17, 2020 |
| NCT01042314 | Completed | Phase 1 | Drug-Drug Interaction Study With Aricept® (Donepezil) | January 2010 | April 2010 |
| NCT05246332 | Completed | N/A | Grounding Effect on Alzheimer's Disease | August 1, 2019 | July 31, 2020 |
| NCT06094452 | Completed | N/A | Effects of 24-week Computerized Cognitive Training in Patients With MCI and AD | October 21, 2020 | August 19, 2022 |
| NCT03994237 | Completed | Accompanying ALZHEIMER CAREGIVER | December 12, 2018 | June 7, 2019 | |
| NCT00046358 | Completed | Phase 4 | The Effect of Short-Term Statins and NSAIDs on Levels of Beta-Amyloid, a Protein Associated With Alzheimer's Disease | September 2002 | August 2005 |
| NCT03058965 | Completed | Early Phase 1 | Phase 0 Evaluation of [18F]MNI-958 as a Potential PET Radioligand for Imaging Tau Protein in the Brain | November 29, 2016 | May 11, 2018 |
| NCT02108769 | Completed | N/A | Yogic Breathing Changes Salivary Components | October 2013 | November 2013 |
| NCT04045990 | Completed | N/A | Network Modulation in Alzheimer's Disease | September 1, 2018 | March 1, 2022 |
| NCT01231295 | Completed | Isotopic Imaging for Prodromal Alzheimer's Disease | February 2011 | September 2016 | |
| NCT00299676 | Completed | An Observational Study of the Safety and Effectiveness of Galantamine in the Treatment of Patients With Alzheimer's Disease Over an 18-month Period | May 2005 | March 2008 | |
| NCT01339130 | Completed | N/A | Assessment of Social-emotional Functioning in Neurological Diseases | June 2009 | June 2013 |
| NCT00285077 | Completed | Phase 2 | Long-Term Safety Extension With SR57667B in Patients With Alzheimer's Disease | March 2004 | November 2006 |
| NCT02172612 | Completed | N/A | A Pilot Study to Reduce Inappropriate Anticholinergic Prescribing in the Elderly | September 2014 | November 20, 2015 |
| NCT00453544 | Completed | N/A | Enhancing Consent for Alzheimer's Research | April 2006 | September 2012 |
| NCT00467766 | Completed | N/A | Combining a Caregiver Intervention With Aricept Treatment for Mild to Moderate Alzheimer's Disease | July 1999 | June 2003 |
| NCT00368459 | Completed | Phase 2 | Raloxifene for Women With Alzheimer's Disease | August 2006 | January 2012 |
| NCT00366288 | Completed | Study Evaluating PAZ-417 in Healthy Young/Elderly | July 2006 | March 2008 | |
| NCT03420807 | Completed | N/A | Retinal Metabolic Imaging of Alzheimer Patient | December 4, 2017 | March 12, 2020 |
| NCT02746484 | Completed | N/A | ABILITY - TelerehABILITation: TechnologY-enhanced Multi-domain at Home Continuum of Care Program | April 2015 | October 2016 |
| NCT04556097 | Completed | N/A | Implementation of the Care Ecosystem Training Model for Individuals With Dementia in a High-risk, Integrated Care Management | December 15, 2020 | November 3, 2021 |
| NCT05806177 | Completed | Phase 1 | Safety, Tolerability and Pharmacokinetics of AD16 Tablets After MAD in Healthy Chinese Adult Subjects | May 26, 2020 | July 31, 2020 |
| NCT03667924 | Completed | N/A | Utilizing Senior Companions to Enhance Dementia Care | April 29, 2019 | August 31, 2020 |
| NCT04515433 | Completed | N/A | Gamma tACS in Alzheimer's Disease | August 20, 2020 | September 30, 2020 |
| NCT00663026 | Completed | Phase 2 | Study Evaluating Bapineuzumab In Alzheimer Disease Subjects | November 2008 | October 2010 |
| NCT03823404 | Completed | Phase 2/Phase 3 | GAIN Trial: Phase 2/3 Study of COR388 in Subjects With Alzheimer's Disease | March 28, 2019 | January 1, 2022 |
| NCT03418688 | Completed | Phase 1 | A Multiple Ascending Dose Study of COR388 | March 6, 2018 | October 15, 2018 |
| NCT04669028 | Completed | Phase 3 | A Phase 3 Study of NE3107 in Probable Alzheimer's Disease | August 5, 2021 | October 25, 2023 |
| NCT02213458 | Completed | N/A | Care Ecosystem: Navigating Patients and Families Through Stages of Care | March 20, 2015 | March 8, 2018 |
| NCT04057807 | Completed | Early Phase 1 | Peripheral Benzodiazepine Receptors (PBR28) Brain PET Imaging With Lipopolysaccharide Challenge for the Study of Microglia Function in Alzheimer's Disease | April 15, 2018 | July 27, 2022 |
| NCT01850238 | Completed | Phase 1 | Safety Study of AADvac1, a Tau Peptide-KLH-Conjugate Active Vaccine to Treat Alzheimer's Disease | May 2013 | March 2015 |
| NCT01009476 | Completed | Long-term Use of Galantamine Versus Nootropics (Memory Enhancing Drugs) in Patients With Alzheimer's Dementia Under Conditions of Daily Routine | March 2006 | August 2008 | |
| NCT00860275 | Completed | Phase 1 | Drug-Drug Interaction (DDI) w/Ketoconazole or Fluconazole | April 2009 | June 2009 |
| NCT04104373 | Completed | The Ontario Neurodegenerative Disease Research Initiative | July 7, 2014 | April 30, 2018 | |
| NCT04384978 | Completed | N/A | Socially Assistive Robots for Interaction With Older Adults With Dementia | January 12, 2020 | April 15, 2022 |
| NCT03298672 | Completed | Phase 1 | Safety, Tolerability, and Pharmacokinetics Study of NDX-1017 | October 9, 2017 | September 5, 2019 |
| NCT05227820 | Completed | Phase 2 | Insulin-Sensitizing Anti-Inflammatory Small Molecule for Investigative Treatment of Dementia | January 19, 2022 | August 20, 2022 |
| NCT01268020 | Completed | Early Phase 1 | Evaluation of [18F] FMH3 and PET as a Marker of Histamine-3 Receptor Activity in Subjects With AD Compared w/ HC | December 2010 | October 2012 |
| NCT01872598 | Completed | Phase 3 | Masitinib in Patients With Mild to Moderate Alzheimer's Disease | January 2012 | December 2020 |
| NCT05544201 | Completed | N/A | Transcranial Alternating Current Stimulation (TACS) for Sleep Disturbances in Neurocognitive Disorders Due to Alzheimer's Disease | October 1, 2022 | February 28, 2024 |
| NCT00684710 | Completed | Phase 1 | Study Evaluating the Safety, Tolerability and Activity of One Dose of PAZ-417 Given to Healthy Japanese Subjects | April 2008 | August 2008 |
| NCT00833274 | Completed | N/A | Evaluation of Apathy Using Attentional Reaction Test in Neurodegenerative Diseases | February 2009 | October 2011 |
| NCT03770182 | Completed | N/A | Brain Stimulation for Neurological Patients | January 1, 2017 | July 27, 2022 |
| NCT02986932 | Completed | N/A | Blood-Brain-Barrier Opening Using Focused Ultrasound With IV Contrast Agents in Patients With Early Alzheimer's Disease | December 2016 | December 2017 |
| NCT05408780 | Completed | Phase 1 | A Phase 1, Two-part, Randomized Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of a Liquid Formulation of Tricaprilin and Matching Placebo in Healthy Subjects | July 14, 2022 | October 24, 2022 |
| NCT04468347 | Completed | Phase 1 | Flortaucipir PET Imaging in the Preclinical, Prodromal and Dementia Phases of Alzheimer's Disease | October 2014 | February 2018 |
| NCT01951118 | Completed | Phase 4 | Olfactory Deficits and Donepezil Treatment in Cognitively Impaired Elderly | October 2013 | May 2019 |
| NCT04842955 | Completed | N/A | Modulators of Gamma tACS in Alzheimer's Disease (Mod-GammAD) | March 10, 2021 | April 30, 2021 |
| NCT00254033 | Completed | Phase 4 | Apathy Associated With Alzheimer's Disease | October 2003 | October 2006 |
| NCT03778151 | Completed | N/A | Repetitive TMS of the Default Mode Network in AD | February 1, 2018 | October 1, 2020 |
| NCT04048759 | Completed | N/A | The Promotion of Physical Activity for the Prevention of Alzheimer's Disease in Adults With Down Syndrome | January 21, 2020 | November 22, 2023 |
| NCT03384043 | Completed | N/A | Comparing Smartphone Technology and a Memory Strategy on Improving Prospective Memory in Alzheimer's Disease | January 8, 2018 | February 28, 2020 |
| NCT00119561 | Completed | N/A | Testing the Effectiveness of Telephone Support for Dementia Caregivers | February 2005 | January 2014 |
| NCT00236574 | Completed | Phase 3 | A Study to Evaluate the Efficacy and Safety of Galantamine in Patients With Mild Cognitive Impairment | May 2001 | November 2003 |
| NCT00380302 | Completed | Phase 1/Phase 2 | Activity of AVE1625 in Mild to Moderate Alzheimer's Patients. | September 2006 | July 2007 |
| NCT04731311 | Completed | N/A | Telerehabilitation Alzheimer's Disease Usability (TADU) | July 29, 2021 | September 7, 2021 |
| NCT03226522 | Completed | Phase 2/Phase 3 | Addressing Dementia Via Agitation-Centered Evaluation | July 13, 2017 | April 17, 2020 |
| NCT03630419 | Completed | Phase 1/Phase 2 | Specialized Food Plan Based on Individual Physiological Comprehensive Body Assessments Accompanied With Cellular Repair Therapy to Decrease Inflammation Cognitively Impaired Patients | February 10, 2018 | July 28, 2018 |
| NCT03691519 | Completed | Phase 3 | Prevention of Cognitive Decline in Older Adults With Low Dha/Epa Index in Red Blood Cells | April 17, 2018 | March 31, 2020 |
| NCT03801642 | Completed | Phase 1/Phase 2 | Dapagliflozin In Alzheimer's Disease | January 29, 2019 | July 7, 2022 |
| NCT03926702 | Completed | Early Phase 1 | Tau Imaging With JNJ067 | June 18, 2019 | January 6, 2021 |
| NCT04333329 | Completed | N/A | Transcranial Pulse Stimulation (TPS) for Alzheimer's Disease (AD) | August 8, 2015 | February 15, 2017 |
| NCT03711825 | Completed | Early Phase 1 | Study to Evaluate Safety/Duration in Stomach of Extended Release Capsules Containing Memantine Hydrochloride in Healthy Adults | September 10, 2018 | November 13, 2018 |
| NCT03554226 | Completed | N/A | Agitation and Aggressivity in Alzheimer's Disease Patients: A Cohort Study | November 1, 2014 | December 31, 2018 |
| NCT01297036 | Completed | Phase 1 | Pharmacokinetic Comparisons of Two Donepezil Formulations | January 2008 | May 2008 |
| NCT00000176 | Completed | Phase 3 | Alzheimer's Disease Prevention Trial | September 2007 | |
| NCT05525780 | Completed | Phase 1 | Dose-Escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics of Donepezil From Single Dose of GB-5001 IM Depot and Aricept® Oral Tablets in Healthy Male Volunteers | August 26, 2022 | June 2, 2023 |
| NCT00912886 | Completed | Pregnenolone Sulfate an Early Marker of the Memory Loss in Alzheimer's Disease | September 2009 | September 2011 | |
| NCT02361242 | Completed | Phase 2 | 24-week Open-label Extension Study Evaluating PXT00864 Effect in Mild AD Patients Further to PLEODIAL-I Completion | June 2013 | December 2015 |
| NCT01566071 | Completed | N/A | Ability to Drive of Early Stage Alzheimer Disease | July 2012 | July 2015 |
| NCT01315717 | Completed | Gait and Alzheimer Interaction Tracking (GAIT) Study | November 2009 | May 2016 | |
| NCT00414622 | Completed | Phase 2 | GTS21-201 for Alzheimer Disease:GTS-21 Administered Daily for 28 Days to Participants With Probable Alzheimer's Disease | November 2006 | April 2007 |
| NCT00593372 | Completed | Phase 1 | Treatment of Language and Memory in Patients With Alzheimer's Disease | August 2003 | April 2010 |
| NCT01796314 | Completed | N/A | Impact of Therapeutic Educational Programme on the Alzheimer's Disease Affected Patient's Quality of Life | January 2013 | February 2017 |
| NCT00297362 | Completed | A Study of the Safety and Effectiveness of Galantamine Hydrobromide in Patients With Alzheimer's Disease | June 2004 | October 2005 | |
| NCT00039702 | Completed | Brain Imaging in Alzheimer's Disease | June 2002 | September 2004 | |
| NCT03466736 | Completed | Enriching Clinical Trials Requiring Amyloid Positivity With Practice Effects | September 1, 2018 | April 20, 2023 | |
| NCT01819714 | Completed | N/A | Sensory Support Care for Elderly Patients Suffering From Alzheimer'S-type Neurodegenerative Disease | June 2013 | February 2015 |
| NCT05082883 | Completed | Cognitive Screening Made Easy for PCPs | August 13, 2021 | May 1, 2023 | |
| NCT03683394 | Completed | N/A | Systematic Multi-domain Alzheimer's Risk Reduction Trial | August 30, 2018 | August 10, 2022 |
| NCT00908492 | Completed | Phase 2/Phase 3 | Supporting Caregivers of Persons With Dementia: A Pilot Study | November 2009 | September 2011 |
| NCT01078168 | Completed | Phase 2 | Alzheimer's Disease Acitretin Medication | March 2010 | May 2013 |
| NCT04413851 | Completed | Feasibility of Passive Data Collection in Dementia Subjects With Agitation | June 1, 2020 | December 6, 2021 | |
| NCT01194713 | Completed | N/A | Effects of Sleep Deprivation on Cerebrospinal Fluid (CSF) Amyloid-beta (Aβ) Dynamics | March 2011 | September 2013 |
| NCT02973971 | Completed | ADDIA Chronobiological Study | November 2016 | March 29, 2018 | |
| NCT03822208 | Completed | Phase 1 | First in Human Study for Safety and Tolerability of AL003. | March 29, 2019 | May 6, 2021 |
| NCT00563732 | Completed | Phase 1 | Study Evaluating Potential Pharmacokinetic (PK) Interaction Between Lecozotan and Digoxin | December 2007 | September 2008 |
| NCT01700556 | Completed | N/A | A Trial to Support Caregivers of Patients With Dementia in Italy: the UP-TECH Project | January 14, 2013 | June 7, 2014 |
| NCT05318040 | Completed | Phase 1 | Safety, Tolerability and Pharmacokinetics of CMS121, a Drug Candidate for Alzheimer's Disease, in Healthy Subjects | May 1, 2022 | December 17, 2022 |
| NCT00000173 | Completed | Phase 3 | Memory Impairment Study (Mild Cognitive Impairment Study) | March 1999 | January 2004 |
| NCT04748666 | Completed | N/A | PST for Care Partners of Adults With Alzheimer's and Alzheimer'S-related Dementia | June 14, 2021 | July 20, 2023 |
| NCT03682185 | Completed | Phase 3 | The Healthy Patterns Sleep Study | May 1, 2016 | May 31, 2021 |
| NCT00255086 | Completed | Phase 3 | The Effect of Memantine on Brain Structure and Chemistry in Alzheimer's Disease Patients | May 2005 | February 2010 |
| NCT05508646 | Completed | N/A | Group-Based Telehealth Music Therapy Intervention for Patients With Dementia: A Pilot Study | January 1, 2023 | January 29, 2024 |
| NCT00556660 | Completed | Phase 1 | Evaluation of [123I] AV51 and SPECT as a Marker of Beta-amyloid Protein Deposition in Subjects With Alzheimer Disease in Comparison to Healthy Subjects | September 2007 | July 2008 |
| NCT00479349 | Completed | Phase 1 | Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of SAM-531 | May 2007 | January 2008 |
| NCT01453569 | Completed | Phase 2 | Safety, Efficacy and Dose Titration of Sodium Oligo-mannurarate Capsule on Mild to Moderate Alzheimer's Disease | October 2011 | August 2013 |
| NCT03533257 | Completed | Phase 2 | Study to Assess the Safety and Biological Activity of AMX0035 for the Treatment of Alzheimer's Disease | August 27, 2018 | August 15, 2021 |
| NCT01837641 | Completed | Phase 1 | A Study of LY3002813 in Participants With Alzheimer's Disease | May 3, 2013 | August 24, 2016 |
| NCT00480818 | Completed | Phase 1 | Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of SAM-531 in Healthy Young and Elderly Subjects | September 2006 | July 2007 |
| NCT05225389 | Completed | Phase 1 | Study to Assess the Absorption, Metabolism, Excretion, and Mass Balance of CT1812 in Healthy Adult Male Subjects | December 31, 2021 | January 24, 2022 |
| NCT03375697 | Completed | Phase 1 | A Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-63733657 in Healthy Subjects and Subjects With Alzheimer's Disease | December 22, 2017 | December 16, 2019 |
| NCT00480467 | Completed | Phase 1 | Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAM-315 in Healthy Japanese Males | September 2006 | August 2007 |
| NCT04063124 | Completed | Phase 1/Phase 2 | Senolytic Therapy to Modulate Progression of Alzheimer's Disease | February 14, 2020 | January 30, 2023 |
| NCT06180252 | Completed | PET Study of Acetylcholine Esterase Activity in Alzheimer's Disease | May 12, 2004 | January 29, 2008 | |
| NCT00501111 | Completed | Phase 2 | Proof of Concept Study of Cognitive Improvement in Patients With Alzheimer's Disease | July 2007 | August 2008 |
| NCT01681602 | Completed | Phase 3 | Effect of Physical Exercise in Alzheimer Patients | January 2012 | June 2014 |
| NCT01430286 | Completed | N/A | Web-based Psycho-Educational Program to Support Carers of Alzheimer's Patients | October 2011 | July 2014 |
| NCT00470418 | Completed | Phase 2 | Development of NIC5-15 in the Treatment of Alzheimer's Disease | January 2007 | March 2010 |
| NCT04305652 | Completed | N/A | The Progressively Lowered Stress Threshold Model | January 1, 2020 | January 30, 2021 |
| NCT04434898 | Completed | The Assessment of the Diagnosis and Prognosis of Patients With Alzheimer Disease or Parkinson Disease With Cognitive Impairment by Using Diffusion MRI | October 1, 2017 | September 30, 2020 | |
| NCT02846415 | Completed | N/A | Play Intervention for Dementia for Promoting Cognitive Function: A Feasibility Study | August 1, 2016 | December 31, 2017 |
| NCT04118985 | Completed | N/A | Compensatory Training to Support Brain Healthy Lifestyle Changes in Those at Risk for Alzheimer's Disease | October 10, 2019 | October 30, 2020 |
| NCT01692977 | Completed | N/A | What Elements of the Design of a Healing Garden Are Used as Landmarks by Patients With Alzheimer's Disease to Locate? | August 2012 | October 2014 |
| NCT04517877 | Completed | Phase 2 | Caring Light Project for Family Caregivers | July 15, 2020 | May 30, 2021 |
| NCT01217021 | Completed | Early Phase 1 | Safety and Efficacy of Positron Emission Tomography (PET) Imaging With MNI-558 | September 2010 | March 2011 |
| NCT05516342 | Completed | N/A | LEAD IT! An App to Enable Persons With Early Stage Dementia to Lead Group Activities for Their Peers | November 10, 2020 | June 11, 2023 |
| NCT05537688 | Completed | Identification of Graphic Markers of Neurocognitive Disorders (MG) | June 27, 2022 | August 27, 2023 | |
| NCT00938665 | Completed | Evaluation of a Handheld Event Related Potential (ERP)/Quantitative Electroencephalography (qEEG) System (COGNISION™) as a Useful Cognitive Biomarker for Alzheimer's Disease. | December 2010 | February 2014 | |
| NCT05515679 | Completed | N/A | The BRAIN App: Building Relationships Using Artificial Intelligence and Nostalgia | July 13, 2022 | December 31, 2022 |
| NCT04555941 | Completed | Phase 2 | The Effects of Intermittent Theta Burst Stimulation in MCI and Early AD | October 5, 2020 | January 31, 2022 |
| NCT04700540 | Completed | N/A | A Mobile Informatics Solution to Aid in Memory | September 1, 2022 | April 1, 2024 |
| NCT03424200 | Completed | N/A | Coaching for Cognition in Alzheimer's (COCOA) | January 10, 2018 | January 1, 2022 |
| NCT00385684 | Completed | Phase 4 | Low-Dose Opiate Therapy for Discomfort in Dementia (L-DOT) | October 2007 | June 2014 |
| NCT00726726 | Completed | Phase 1 | Drug Interaction Study With a Potential Alzheimer's Disease Compound | August 2008 | October 2008 |
| NCT03442322 | Completed | N/A | Optimizing Care for Patients With Dementia | March 15, 2018 | July 26, 2022 |
| NCT05642052 | Completed | N/A | Feasibility Study of a Community Pilot Project for the Prevention of Alzheimer's Disease: the KetoHome Study. | November 28, 2022 | March 28, 2024 |
| NCT05395559 | Completed | Prevalence and Recognition of Cognitive Impairment in Hospitalized Patients: a Flash Mob Study | September 21, 2022 | September 21, 2022 | |
| NCT02997982 | Completed | Phase 2 | Feasibility and Effects of Valaciclovir Treatment in Persons With Early Alzheimer's Disease | December 2016 | March 4, 2020 |
| NCT04268953 | Completed | Phase 1 | Study to Compare the Pharmacokinetics of Daily Administration of Tricaprilin on Ketone Body Production | February 27, 2020 | May 1, 2020 |
| NCT00041678 | Completed | Phase 3 | Study of Aripiprazole in the Treatment of Patients With Psychosis Associated With Dementia of the Alzheimer's Type | January 2000 | March 2003 |
| NCT03397667 | Completed | N/A | The Aging Brain ANSWERS Program | August 1, 2018 | May 31, 2023 |
| NCT00000174 | Completed | Phase 3 | Investigation Into Delay to Diagnosis of Alzheimer's Disease With Exelon (InDDEx) | ||
| NCT02178124 | Completed | Phase 1 | A Phase I Clinical Study, Randomized, Single-blind, Placebo-controlled, Multiple Doses, Dose Escalation Study of the Safety, Tolerability and Pharmacokinetics of Donepezil Patch in Healthy Male Subjects. | July 2014 | December 2014 |
| NCT05503511 | Completed | Phase 1 | Safety and Pharmacokinetic Study of NPT 2042 Soft-gelatin Capsules Administered Orally to Healthy Adult Subjects | October 20, 2022 | March 30, 2023 |
| NCT03119961 | Completed | Phase 1/Phase 2 | Blood Brain Barrier Opening in Alzheimer' Disease | June 26, 2017 | October 7, 2020 |
| NCT03134963 | Completed | Cerebral Haemodynamic Changes During Cognitive Testing: A fTCD Study | May 5, 2017 | December 1, 2017 | |
| NCT00000177 | Completed | Phase 3 | Estrogen Hormone Protocol | October 1995 | January 1999 |
| NCT00105638 | Completed | N/A | Telehealth Education Program for Caregivers of Veterans With Dementia | September 2005 | April 2007 |
| NCT02050464 | Completed | Computational Tools for Early Diagnosis of Memory Disorders | December 2013 | April 2017 | |
| NCT01183806 | Completed | Phase 3 | Effects of Exercise and Rivastigmine on Quality of Life of Alzheimer's Disease Patients | July 2010 | March 2012 |
| NCT03446001 | Completed | Phase 3 | Safety and Efficacy of TRx0237 in Subjects With Alzheimer's Disease Followed by Open-Label Treatment | January 10, 2018 | April 4, 2023 |
| NCT00261573 | Completed | Phase 3 | A Study of the Safety and Effectiveness of Galantamine Versus Placebo in the Treatment of Patients With Vascular Dementia or Mixed Dementia | December 1998 | December 2000 |
| NCT02788513 | Completed | Phase 2 | BI 425809 in Patients With Cognitive Impairment Due to Alzheimer's Disease. | August 11, 2016 | October 11, 2019 |
| NCT05444244 | Completed | N/A | A Relational Research Recruitment and Engagement Intervention for Cognitive Aging Research | August 1, 2022 | May 31, 2023 |
| NCT00056628 | Completed | Phase 3 | COGNIShunt® System for Alzheimer's Disease | January 2001 | October 2004 |
| NCT00017940 | Completed | Phase 1 | Gene Therapy for Alzheimer's Disease Clinical Trial | November 2003 | |
| NCT03723707 | Completed | N/A | Enhanced Quality in Primary Care for Elders With Diabetes and Dementia | December 3, 2018 | October 20, 2022 |
| NCT03510572 | Completed | Early Phase 1 | Evaluation of [18F]PI-2620 as a Potential Positron Emission Computed Tomography Radioligand for Imaging Tau Protein in the Brain | June 4, 2018 | July 31, 2019 |
| NCT05202223 | Completed | N/A | Harmony at Home: A Pilot Telehealth Program for Rural ADRD Caregivers | January 15, 2022 | December 8, 2022 |
| NCT00870974 | Completed | Phase 1 | A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions | March 2009 | November 2016 |
| NCT05599100 | Completed | N/A | Virtual Training for Latino Caregivers to Manage Symptoms of Dementia | May 5, 2023 | January 15, 2024 |
| NCT03093519 | Completed | Phase 1 | A Repeated Dose Study of KHK6640 in Japanese Patients With Alzheimer's Disease | March 3, 2017 | December 6, 2017 |
| NCT00498602 | Completed | Phase 2 | Study Evaluating ACC-001 In Subjects With Mild To Moderate Alzheimer's Disease | November 2007 | February 2013 |
| NCT04533815 | Completed | N/A | Enhancing Sleep Quality for Nursing Home Residents With Dementia | May 5, 2021 | August 31, 2022 |
| NCT04442594 | Completed | N/A | REMINISCENCES and EMOTIONS : Reminiscence Triggered by Virtual Reality for Older Adults With Mood Disorders | December 2, 2020 | February 1, 2023 |
| NCT00141661 | Completed | Phase 2 | A Safety and Tolerability Evaluation of Two 10-Week Dose Regimens of Orally-Administered PF-04494700 in Alzheimer's Patients | October 2005 | June 2006 |
| NCT03071224 | Completed | Early Phase 1 | Phase 1 Evaluation of [18F]MK-6240 PET as an Imaging Marker for Tau Protein | June 2016 | June 9, 2021 |
| NCT00147693 | Completed | N/A | Systematic Care for Informal Caregivers of Dementia Patients: An Efficient Approach? | June 2005 | February 2006 |
| NCT01057030 | Completed | Phase 1 | Multiple Dose Japanese Bridging Study | March 2010 | June 2010 |
| NCT04103580 | Completed | N/A | Caregiver Speaks: A Technologically Mediated Storytelling Intervention | March 1, 2020 | August 31, 2023 |
| NCT05697380 | Completed | N/A | CB3 Pilot (Communication Bridge: A Person-centered Internet-based Intervention for Individuals With Primary Progressive Aphasia) | June 1, 2021 | July 12, 2023 |
| NCT05803122 | Completed | Validation of the I-UDS Neuropsychological Battery | July 15, 2022 | December 30, 2022 | |
| NCT03653871 | Completed | N/A | Caregiver Study Dr. Phillips | September 11, 2018 | December 31, 2019 |
| NCT03373604 | Completed | Phase 2 | Imaging Tau in Alzheimer's Disease and Normal Aging | December 11, 2017 | May 11, 2022 |
| NCT00417482 | Completed | Phase 4 | Antipsychotic Discontinuation in Alzheimer's Disease | August 2004 | April 2011 |
| NCT03340571 | Completed | Blood Biomarker of Alzheimer's Disease (AD) | March 12, 2018 | July 31, 2019 | |
| NCT03944460 | Completed | Phase 1 | SAD Phase I Study (First-in-human) to Investigate Contraloid Acetate | April 9, 2018 | July 27, 2018 |
| NCT00103649 | Completed | Phase 3 | 18-Month Study of the Efficacy of Xaliproden (SR57746A) in Patients With Mild-to-Moderate Dementia of the Alzheimer's Type | November 2003 | October 2007 |
| NCT03197740 | Completed | Phase 3 | A Multinational, Multi-center, Randomized, Double-blind, Active Comparator, Phase III Clinical Trial to Evaluate the Efficacy and Safety of Donepezil Transdermal Patch in Patients With Alzheimer's Disease | October 12, 2017 | July 20, 2020 |
| NCT00013923 | Completed | Phase 2 | Effectiveness of A Nutritional Brain Metabolic Enhancer for Alzheimer Disease | June 2005 | |
| NCT00645190 | Completed | Phase 3 | A Randomized, Double-blind, Flexible Dose, Multicenter Study to Evaluate the Effectiveness and Safety of Galantamine IR in Mild to Moderate Alzheimer's Disease | March 2004 | February 2005 |
| NCT03920826 | Completed | N/A | Transcranial Alternating Current Stimulation for Patients With Mild Alzheimer's Disease (TRANSFORM-AD) | September 11, 2019 | April 15, 2022 |
| NCT04300933 | Completed | N/A | Neurofeedback Intervention for Preclinical Alzheimer's Disease | April 1, 2019 | December 31, 2019 |
| NCT03173846 | Completed | Multiregional rtfMRI Neurofeedback for the Prevention of Alzheimer's Disease (NPAD) | May 5, 2017 | December 31, 2019 | |
| NCT03224988 | Completed | Bilateral Brain Dynamics in Cognition and Aging | March 20, 2018 | January 20, 2022 | |
| NCT01746498 | Completed | N/A | Therapeutic Effect of Direct Current Stimulation on Cognitive Function of Mild to Moderate Alzheimer Patients | June 2011 | November 2012 |
| NCT03250741 | Completed | Phase 2 | Effects of Dopaminergic Therapy in Patients With Alzheimer's Disease | June 2016 | November 2018 |
| NCT03184467 | Completed | Phase 2 | Clinical Trial to Evaluate the Efficacy and Safety of GV1001 in Alzheimer Patients | September 5, 2017 | September 19, 2019 |
| NCT03887923 | Completed | N/A | Vestibular Physical Therapy for People With Alzheimer Disease | May 10, 2019 | December 31, 2019 |
| NCT01880151 | Completed | N/A | Neuroelectrical Biomarkers for Alzheimer's Disease Stages | July 12, 2013 | January 2019 |
| NCT00253188 | Completed | Phase 3 | A Study of the Safety and Effectiveness of Two Doses of Galantamine Versus Placebo in the Treatment of Patients With Alzheimer's Disease | February 1997 | December 1998 |
| NCT03290040 | Completed | Identification of Predictors for Early Cognitive Decline in Men | January 2015 | December 2022 | |
| NCT00294307 | Completed | Enhancing Care Coordination: Hospital to Home for Cognitively Impaired Older Adults and Their Caregivers | February 2006 | August 2012 | |
| NCT03981380 | Enrolling by invitation | 11C-PIB PET Study in MESA at Columbia University | August 1, 2020 | June 30, 2025 | |
| NCT05575076 | Enrolling by invitation | Phase 3 | Open-label Extension for Phase 3 Clinical Trials of Simufilam | November 7, 2022 | July 15, 2026 |
| NCT06114914 | Enrolling by invitation | TapTalkTest Project:Development of a Non-invasive Screening Test to Detect Risk of Alzheimer's Disease Pathology | August 1, 2022 | December 31, 2025 | |
| NCT04786223 | Enrolling by invitation | Phase 2 | Targeting Neuroinflammation as a Contributing Pathology in Alzheimer's Disease Dementia | March 30, 2021 | March 2025 |
| NCT06234436 | Enrolling by invitation | Early Phase 1 | Plasma Dilution and Infusion to Improve Cognition in Mild Cognitive Impairment (MCI) | December 7, 2023 | December 31, 2025 |
| NCT06029114 | Enrolling by invitation | MR Elastography of Cognitive Impairment | October 11, 2023 | November 2027 | |
| NCT05477862 | Enrolling by invitation | N/A | Neural Mechanisms of Clinically Designed Improvisatory Music for Alzheimer's Disease | October 15, 2023 | January 15, 2026 |
| NCT06023407 | Enrolling by invitation | N/A | Feasibility of Improving Glycemia With Heat Therapy to Prevent AD | February 27, 2024 | January 1, 2027 |
| NCT06246019 | Enrolling by invitation | The Clinical Impact of the Novel Alzheimer's Blood-based Biomarkers | February 7, 2024 | December 31, 2025 | |
| NCT04948866 | Enrolling by invitation | N/A | Palliative Care for Persons With Late-stage Alzheimer's and Related Dementias and Their Caregivers | July 26, 2021 | September 30, 2024 |
| NCT04886063 | Enrolling by invitation | Phase 2/Phase 3 | Open Label Study of ATH-1017 for Treatment of Mild to Moderate Alzheimer's Disease | June 30, 2021 | February 2027 |
| NCT06285448 | Enrolling by invitation | Feasibility of Lecanemab Registry and Clinical Outcome Measures | January 2, 2024 | June 30, 2026 | |
| NCT03089827 | Enrolling by invitation | Biodistribution of [11C]PIB in Patients With Risk Factors for Alzheimer's Disease | May 21, 2014 | April 2031 | |
| NCT04510168 | Enrolling by invitation | Accelerated Non-Atherosclerotic Brain Arterial Aging Relationship to Alzheimer's Disease | September 18, 2020 | April 2025 | |
| NCT04949529 | Enrolling by invitation | Falls: A Marker of Preclinical AD | March 7, 2019 | April 2025 | |
| NCT03724136 | Enrolling by invitation | N/A | Alzheimer's Autism and Cognitive Impairment Stem Cell Treatment Study | October 24, 2018 | July 31, 2025 |
| NCT05584241 | Enrolling by invitation | N/A | Behavioral Change Following Alzheimer's Disease (AD) Biomarker Disclosure | February 20, 2023 | August 2026 |
| NCT04250376 | Enrolling by invitation | N/A | The Use of Transcranial Focused Ultrasound for the Treatment of Neurodegenerative Dementias | November 27, 2017 | January 2025 |
| NCT05704309 | Enrolling by invitation | The Diabetes Prevention Program Outcomes Study AD/ADRD Project | November 7, 2022 | August 30, 2027 | |
| NCT04851691 | Enrolling by invitation | N/A | An Electronic Clinical Decision Support Tool to Reduce Low-value Antipsychotic Prescriptions | August 3, 2021 | July 31, 2024 |
| NCT05990114 | Enrolling by invitation | N/A | Evaluation of the Structured Caregiver Support Program (SCSP) in Terms of Various Parameters | September 2023 | November 2023 |
| NCT02414178 | Enrolling by invitation | F 18 T807 Tau PET Imaging in Dominantly Inherited Alzheimer's Network (DIAN Project) | March 1, 2021 | September 2024 | |
| NCT04701177 | Enrolling by invitation | Digitally-enhanced, Decentralized, Multi-omics Observational Cohort | March 15, 2021 | November 30, 2026 | |
| NCT04104659 | Enrolling by invitation | Study of Tau Imaging With the Use of [18F]MK-6240 Tracer | March 1, 2021 | June 1, 2024 | |
| NCT06023446 | Enrolling by invitation | Can (Optical Coherence Tomography) Pictures of the Retina Detect Alzheimer's Disease at Its Earliest Stages? | September 29, 2023 | February 28, 2028 | |
| NCT05973448 | Enrolling by invitation | N/A | The Nightlight Falls Prevention Study | July 28, 2023 | August 31, 2026 |
| NCT06017505 | Enrolling by invitation | Integrating eSAGE With EHR Data Using Machine Learning for the Early Detection and Monitoring of Cognitive Impairment in Individuals | June 1, 2024 | September 2025 | |
| NCT06022068 | Enrolling by invitation | Phase 1/Phase 2 | Evaluating Rapamycin Treatment in Alzheimer's Disease Using Positron Emission Tomography | September 1, 2023 | January 31, 2025 |
| NCT06424652 | Enrolling by invitation | N/A | Effect of Physiologic Insulin Administration on Cognition | May 16, 2024 | June 16, 2024 |
| NCT04947553 | Enrolling by invitation | Phase 3 | A Study to Assess the Long-term Safety and Efficacy of AXS-05 in Subjects With Alzheimer's Disease Agitation | June 17, 2021 | December 2024 |
| NCT04785300 | Enrolling by invitation | Phase 1/Phase 2 | ALSENLITE: Senolytics for Alzheimer's Disease | July 6, 2022 | December 2024 |
| NCT04954183 | Enrolling by invitation | Development of an EEG Diagnostic for Alzheimer's Disease | October 1, 2021 | June 2024 | |
| NCT06245031 | Enrolling by invitation | N/A | Extension to a Pivotal Study of Sensory Stimulation in Alzheimer's Disease (OLE Hope Study, CA-0015) | February 29, 2024 | March 2027 |
| NCT05597124 | Enrolling by invitation | Phase 2 | Exercise to Improve Brain Health in Older African Americans | April 11, 2023 | March 2028 |
| NCT01435551 | No longer available | Using Hypnotherapy For Dementia & Alzheimer's | |||
| NCT04855955 | No longer available | Autologous Human Adipose-Derived Mesenchymal Stem Cells in Alzheimer's Disease | |||
| NCT03564964 | No longer available | Expanded Access to Provide SUVN-502 for the Treatment of Subjects With Alzheimer's Disease | |||
| NCT05796037 | Not yet recruiting | An Observational Study of Patients Living With Chronic Neurological Diseases | August 1, 2024 | December 31, 2038 | |
| NCT04004702 | Not yet recruiting | Phase 2 | Levetiracetam for Alzheimer's Disease Neuropsychiatric Symptoms Related to Epilepsy Trial (LAPSE) | January 2020 | June 2025 |
| NCT05831371 | Not yet recruiting | Discard the Curative Causes of Late Onset Epilepsy: the Role of Brain 18F-FDG PET | May 2, 2023 | September 2, 2023 | |
| NCT05460143 | Not yet recruiting | Optical Neuroimaging and Cognition | March 1, 2023 | September 1, 2025 | |
| NCT05985486 | Not yet recruiting | N/A | Brain Outcomes With Lifestyle Change in Down Syndrome | October 1, 2024 | September 30, 2027 |
| NCT06367231 | Not yet recruiting | SCGs as a Proxy for Determining the Cognitive Status of Older Adults | May 1, 2024 | July 1, 2025 | |
| NCT06079216 | Not yet recruiting | N/A | Making Connections Thru Music | December 1, 2024 | September 30, 2025 |
| NCT06120049 | Not yet recruiting | Phase 2/Phase 3 | [18F]-MFBG Versus [123I]-MIBG and [18F]-PE2I in PD vs. MSA and DBL vs. AD | December 2023 | December 2026 |
| NCT05809908 | Not yet recruiting | Phase 3 | Tricaprilin Phase 3 AD Study | January 2025 | January 2028 |
| NCT06301750 | Not yet recruiting | N/A | Oral Enteral Nutrition Feeding in Alzheimer's Patients | March 2024 | June 2024 |
| NCT06445582 | Not yet recruiting | SV2A-PET/CT and PET/MRI Combined Clinical Criteria Score in the Diagnosis of Early Cognitive Alteration | June 2024 | December 2025 | |
| NCT05564169 | Not yet recruiting | Phase 3 | Masitinib in Patients With Mild to Moderate Alzheimer's Disease | January 2024 | December 2026 |
| NCT06403345 | Not yet recruiting | N/A | A Green Activity Prescription Program for Hispanic/Latino (Latinx) Persons Living With Dementia | April 29, 2024 | November 30, 2024 |
| NCT05509387 | Not yet recruiting | N/A | Investigating if a Stronger tDCS Intensity is More Effective for Improving Naming Ability in People Living With Alzheimer's Disease | September 1, 2022 | December 31, 2026 |
| NCT05521477 | Not yet recruiting | N/A | Dynamic Response to Probiotics in Context of Alzheimer Disease: a Proof-of-concept Study | September 1, 2022 | September 1, 2023 |
| NCT05163626 | Not yet recruiting | N/A | Combined Aerobic Exercise and Cognitive Training in Seniors at Increased Risk for Alzheimer's Disease | December 2024 | December 2034 |
| NCT06045988 | Not yet recruiting | Phase 2 | Automated, Assistive, Non-Contact Sleep Quality Monitor for Individuals With Alzheimer's Disease | February 1, 2025 | April 2025 |
| NCT04571502 | Not yet recruiting | N/A | Integration of Health Information Technology and Promotion of Personhood in Family-Centered Dementia Care | July 2024 | May 31, 2025 |
| NCT06432166 | Not yet recruiting | Phase 1/Phase 2 | 2-Hydroxybenzylamine (2-HOBA) Study in Early Alzheimer's Patients | July 1, 2024 | December 31, 2027 |
| NCT06379100 | Not yet recruiting | N/A | Cerebellar iTBS Mode Transcranial Magnetic Stimulation for the Treatment of Alzheimer's Disease | May 20, 2024 | September 25, 2024 |
| NCT05163067 | Not yet recruiting | N/A | Combined Aerobic Exercise and Cognitive Training in Seniors With Genetic Susceptibility for Alzheimer's Disease | December 2024 | December 2034 |
| NCT05882344 | Not yet recruiting | N/A | Deep Brain Stimulation for Alzheimer's | February 1, 2025 | October 2028 |
| NCT06377033 | Not yet recruiting | N/A | Using the EHR to Advance Genomic Medicine Across a Diverse Health System | May 1, 2024 | June 30, 2027 |
| NCT06223438 | Not yet recruiting | Detecting an MCI and Amyloid Digital Neuro Signature(DNS) Using Altoida's Multimodal Digital Biomarkers. | January 15, 2024 | July 1, 2024 | |
| NCT05575271 | Not yet recruiting | N/A | Implantable Vagus Nerve Stimulation Modulation of Coeruleus-Norepinephrine Network for Mild-Moderate AD Patients | November 1, 2022 | December 31, 2026 |
| NCT06068361 | Not yet recruiting | Diagnostic Evaluation of Dementia With Lewy Bodies Using a Multimodal Approach | July 2024 | July 2027 | |
| NCT05389644 | Not yet recruiting | N/A | TMS as a Treatment for Apathy in Alzheimer's Disease | November 15, 2023 | July 1, 2025 |
| NCT06371053 | Not yet recruiting | N/A | The Effect of Community Intervention on Different Degrees of Dementia | April 2024 | May 2024 |
| NCT06169826 | Not yet recruiting | Phase 4 | Histidine Oral Supplementation as a Therapeutic Modality for Alzheimer's Disease | June 2024 | April 2026 |
| NCT06328374 | Not yet recruiting | Voice and Swallowing Disorders in Adults With and Without Alzheimer's Disease | June 2024 | December 2026 | |
| NCT06298474 | Not yet recruiting | N/A | The BRAIN App (Phase 2 SBIR) | February 15, 2025 | November 30, 2025 |
| NCT05909189 | Not yet recruiting | N/A | LEADing Dementia End-of-Life Planning Conversations | February 1, 2024 | June 30, 2027 |
| NCT05762926 | Not yet recruiting | N/A | Non-invasive Brain Stimulation by Transcranial Pulse Stimulation as a Coadjunctive Treatment in Alzheimer's Disease | August 1, 2023 | May 2, 2024 |
| NCT05929924 | Not yet recruiting | N/A | Does EVOO Induce Gene and Metabolic Changes in Healthy Subjects | August 1, 2023 | December 31, 2024 |
| NCT05599425 | Not yet recruiting | N/A | Health Behavior Change in Midlife Adults at Risk for Alzheimer's Disease | April 1, 2023 | April 30, 2024 |
| NCT05104593 | Not yet recruiting | N/A | An Integrated Solution for Sustainable Care for Multimorbid Elderly Patients With Dementia | January 1, 2024 | December 31, 2025 |
| NCT06325527 | Not yet recruiting | Cognitive Impairment Cohort Study of the Elderly Population in YuGarden | April 1, 2024 | June 1, 2031 | |
| NCT04437290 | Not yet recruiting | University of Washington Alzheimer's Disease Research Center (UW ADRC) Imaging & Biomarker Core | November 2022 | April 30, 2025 | |
| NCT06242574 | Not yet recruiting | Meaningful Aspects of Health for Adults With Dementia, Their Care Partners and Healthcare Practitioners | April 15, 2024 | March 1, 2025 | |
| NCT06328829 | Not yet recruiting | N/A | Intermittent Oral Tube in Alzheimer's Patients | March 2024 | December 2024 |
| NCT06372821 | Not yet recruiting | Phase 1 | A Trial Evaluating the Effect of NIO752 on Tau Synthesis Measured by a Process Known as SILK | May 2024 | August 2025 |
| NCT06412185 | Not yet recruiting | Phase 1 | Single Dose Escalation Study of CM383 in Healthy Volunteers | June 30, 2024 | June 30, 2025 |
| NCT06321380 | Not yet recruiting | Working Memory Functioning in Alzheimer's Disease and Vascular Dementia | April 2024 | October 2025 | |
| NCT05194163 | Not yet recruiting | Phase 2 | MW150 Stress Kinase Inhibitor in Mild to Moderate Alzheimer's Disease | May 1, 2022 | November 30, 2024 |
| NCT05904132 | Not yet recruiting | N/A | Individual Closed-Loop Neuromodulation Therapy for Alzheimer's Disease | July 2024 | July 2025 |
| NCT06081569 | Not yet recruiting | Multimodal Deep Learning for the Diagnosis and Assessment of Alzheimer's Disease | October 15, 2023 | October 15, 2026 | |
| NCT03899298 | Not yet recruiting | Phase 1 | Safety and Clinical Outcomes With Amniotic and Umbilical Cord Tissue Therapy for Numerous Medical Conditions | September 1, 2019 | March 20, 2029 |
| NCT06416137 | Not yet recruiting | Dementia in Migrants Living in Italy: Promoting a Diversity-sensitive Clinical Approach and Provision of Care | June 30, 2024 | June 30, 2025 | |
| NCT05508841 | Not yet recruiting | N/A | Understanding How Alzheimer's Disease Impacts the Therapeutic Response to Transcranial Direct Current Stimulation | September 1, 2022 | December 31, 2026 |
| NCT06313944 | Not yet recruiting | German Registry of Alzheimer's Disease Treated With Transcranial Pulse Stimulation | April 1, 2024 | October 1, 2026 | |
| NCT05805215 | Not yet recruiting | N/A | Noninvasive Temporal Interference Stimulation: Modulating Associative Memory by Targeting Deep-brain Targets | January 30, 2024 | December 12, 2025 |
| NCT05667935 | Not yet recruiting | Cognitive Impairment Cohort Study of the Elderly Population in SheMountain | December 26, 2022 | January 31, 2031 | |
| NCT06347172 | Not yet recruiting | N/A | Deprescribing in Patients Living With Dementia With Caregiver and Provider Nudges | June 17, 2024 | February 15, 2025 |
| NCT05183321 | Not yet recruiting | N/A | Treatment of Periodontal Disease in Patients With Alzheimer's Disease | June 1, 2024 | December 31, 2026 |
| NCT06213766 | Not yet recruiting | N/A | Spatial and Ocular Trajectories for the Early Diagnosis of Alzheimer's Disease. | March 1, 2024 | September 1, 2025 |
| NCT06448975 | Not yet recruiting | N/A | An Exploratory Study of Deep Cervical Lymphovenous Bypass (LVB) in Alzheimer's Disease | May 31, 2024 | July 1, 2026 |
| NCT05806697 | Not yet recruiting | N/A | Investigation of AlzHeimer's Predictors in Subjective Memory Complainers - Extension Study | April 17, 2023 | December 2029 |
| NCT06373094 | Not yet recruiting | Phase 1 | A Single Dose Escalation Study of HHT201 in Healthy Subjects | June 1, 2024 | March 31, 2025 |
| NCT05473325 | Not yet recruiting | Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY) | January 1, 2023 | June 22, 2025 | |
| NCT05532644 | Not yet recruiting | Correlation of P-glycoprotein Polymorphisms With Microbial Metabolites in Patients With Alzheimer's Disease on Medication | September 2022 | September 2024 | |
| NCT03454646 | Not yet recruiting | Phase 4 | Comparison of Therapeutic Strategies With Cholinesterase Inhibitors (SOS TRIAL) | June 1, 2024 | September 15, 2027 |
| NCT05765552 | Not yet recruiting | N/A | Effects of Dual-Task Training In Individuals With Alzheimer | April 15, 2023 | April 15, 2024 |
| NCT05245903 | Not yet recruiting | Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside | May 2022 | April 30, 2025 | |
| NCT06297590 | Not yet recruiting | Phase 1 | A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease | June 2024 | February 2027 |
| NCT06346275 | Not yet recruiting | N/A | Effect of Acupuncture on the Gait Disturbance and Hemodynamic Changes in the Prefrontal Cortex | July 1, 2024 | April 2025 |
| NCT06391853 | Not yet recruiting | N/A | Investigating Brain Insulin Resistance In Alzheimer Disease With IntraNasal Insulin : A Multimodal Neuroimaging Study | June 1, 2024 | October 1, 2026 |
| NCT05143528 | Not yet recruiting | Phase 3 | Evaluating the Efficacy and Safety of Nilotinib BE in Subjects With Early Alzheimer's Disease | February 1, 2022 | June 1, 2026 |
| NCT06410157 | Not yet recruiting | N/A | Heartrate and Breathing Effects on Attention and Memory | July 2024 | November 2027 |
| NCT03121066 | Not yet recruiting | N/A | Transcranial Magnetic Stimulation for Alzheimer's Disease Treatment | November 2023 | December 2024 |
| NCT05899764 | Not yet recruiting | Phase 1/Phase 2 | Epileptic Hippocampus in Alzheimer's Disease | June 1, 2023 | June 1, 2029 |
| NCT06362707 | Not yet recruiting | Phase 2 | Fasudil Trial for Treatment of Early Alzheimer's Disease (FEAD) | May 1, 2024 | October 1, 2026 |
| NCT05793372 | Not yet recruiting | Hyperhomocysteinemia in Alzheimer's Disease | June 2023 | March 1, 2026 | |
| NCT06368115 | Not yet recruiting | N/A | A Program to Reduce Inappropriate Medications Among Older Adults With Alzheimer's Disease: Implementation Phase 2 | June 2024 | June 2025 |
| NCT06254469 | Not yet recruiting | Phase 3 | Visualizing Brain Proteinopathies Using [F-18]Flornaptitril-PET in the Prediction of Clinical Progression of Mild Cognitive Impairment With Either Suspected Chronic Traumatic Encephalopathy or Alzheimer's Disease | March 1, 2024 | December 31, 2026 |
| NCT05430867 | Not yet recruiting | Phase 4 | Efficacy and Safety of Memantine and Sodium Oligomannate in Patients With Moderate to Severe Alzheimer's Disease | July 1, 2022 | December 31, 2024 |
| NCT05672732 | Not yet recruiting | Assessment of Clinical Trial Experiences of Alzheimer's Disease Patients | February 2024 | February 2026 | |
| NCT06385106 | Not yet recruiting | N/A | Effects of Repetitive Transcranial Magnetic Stimulation in Patients With Alzheimer's Disease | April 2024 | January 2025 |
| NCT06135051 | Not yet recruiting | Phase 1/Phase 2 | Ultrasonic Neuromodulation for Treatment of Cognitive Impairment | April 2024 | April 2027 |
| NCT06417086 | Not yet recruiting | N/A | Clinical Evaluation of Acupuncture Treatment on Alzheimer's Disease in APOE e4 Carriers and Non-Carriers | June 1, 2024 | November 30, 2026 |
| NCT04482413 | Not yet recruiting | Phase 2 | Study to Evaluate the Safety and Efficacy of AstroStem in Treatment of Alzheimer's Disease | February 1, 2023 | December 20, 2024 |
| NCT06079203 | Not yet recruiting | N/A | ED-LEAD: Emergency Departments Leading the Transformation of Alzheimer's and Dementia Care | June 1, 2024 | August 2028 |
| NCT06444841 | Not yet recruiting | N/A | Paper-Based and Smartphone-Based Memory Supports | June 1, 2024 | September 30, 2028 |
| NCT04760171 | Not yet recruiting | Amyloid Proteins From Medullary Thyroid Cancer and Laryngeal Amyloidosis | February 2021 | February 2026 | |
| NCT05114499 | Not yet recruiting | Efficacy and Safety of Donepezil and Sodium Oligomannate in Patients With Mild to Moderate Alzheimer's Disease | December 2021 | December 2024 | |
| NCT05527405 | Not yet recruiting | N/A | Efficacy of Caregiver Training Program in Enhancing Caregiver and Patient Outcomes | March 2024 | August 2025 |
| NCT06021704 | Not yet recruiting | N/A | The Care for America's Aging Study | July 1, 2024 | December 31, 2026 |
| NCT06416267 | Not yet recruiting | Risk and Clinical Consequences of Low Count Monoclonal B-cell Lymphocytosis (LC MBL) | August 2024 | December 2040 | |
| NCT05761665 | Not yet recruiting | Comparison of Kinesiophobia, Balance, Falling and Walking Speeds of Elderly's With Physical Frailty With Alzheimer's | June 2023 | February 29, 2024 | |
| NCT06168955 | Not yet recruiting | N/A | Study of N-homocysteinylation of Key Proteins in Alzheimer's Disease (HO-MA) | February 2024 | December 2025 |
| NCT05516134 | Not yet recruiting | N/A | All About Me: An Intervention to Ease the Transition to Long Term Care | March 28, 2024 | June 15, 2024 |
| NCT06042413 | Not yet recruiting | N/A | Prediction and Prevention of Postoperative Mortality and Morbidity | July 1, 2024 | September 1, 2025 |
| NCT06459583 | Not yet recruiting | N/A | Evaluation of Self-Mediated Alternatives for Risk Testing Education and Return of Results | June 2024 | November 2025 |
| NCT05143255 | Not yet recruiting | N/A | Developing a Communication Intervention for People With Memory Changes and Their Caregivers | March 2024 | September 2024 |
| NCT06202872 | Not yet recruiting | N/A | Memory Enhancement Using Transcranial Alternating Current Stimulation | February 1, 2024 | February 1, 2026 |
| NCT06427668 | Not yet recruiting | Phase 2 | Study of SPG302 in Adult Participants With Mild-to-Moderate Alzheimer's Disease (AD) | July 2024 | June 2026 |
| NCT05924425 | Recruiting | Phase 4 | Daridorexant to Treat Insomnia in Patients With Mild Cognitive Impairment and Mild to Moderate Alzheimer Disease | March 13, 2024 | March 13, 2027 |
| NCT03665831 | Recruiting | N/A | Deep TMS for Comorbid Depression and Cognitive Impairment in Older Adults | October 23, 2018 | September 15, 2024 |
| NCT05886114 | Recruiting | N/A | A Multi-domain Lifestyle Intervention Among Aged Community-residents in Zhejiang, China | May 28, 2023 | April 28, 2027 |
| NCT06174038 | Recruiting | N/A | Early Age-Related Hearing Loss Investigation (EARHLI) | April 1, 2024 | February 1, 2028 |
| NCT05151562 | Recruiting | N/A | Music Therapy for Patients With Alzheimer's Disease | July 18, 2022 | April 2026 |
| NCT05661084 | Recruiting | N/A | Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia | January 24, 2023 | August 31, 2027 |
| NCT05464368 | Recruiting | Phase 1 | R21 Roche: 3-Way Tau Tracers in AD | February 1, 2023 | June 2027 |
| NCT05406778 | Recruiting | N/A | SPARK Neuro REMIND Study | May 18, 2022 | November 2025 |
| NCT05798637 | Recruiting | PIPAF Platelets in the Pathogenesis of Ageing Associated Frailty | February 10, 2020 | November 2023 | |
| NCT03020381 | Recruiting | Gait as Predictor of Dementia and Falls. The Gait and Brain Cohort Study | December 2007 | January 2033 | |
| NCT05527587 | Recruiting | N/A | The Effects of a Park Visit Program on Individuals With Dementia and Their Caregivers | November 1, 2022 | December 31, 2024 |
| NCT05507905 | Recruiting | N/A | Effects of Dance and Music Appreciation on Brain Health and Fitness in People at Risk for Alzheimer's Disease | April 24, 2023 | March 2027 |
| NCT05457998 | Recruiting | BioFINDER-Brown: Examination of Alzheimer's Disease Biomarkers | June 14, 2023 | June 2028 | |
| NCT04134923 | Recruiting | Imaging Biomarkers in Preclinical and Symptomatic AD | June 8, 2021 | October 2029 | |
| NCT05637801 | Recruiting | N/A | A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (Hope Study, CA-0011) | December 13, 2022 | July 2025 |
| NCT03144921 | Recruiting | N/A | EPIC: An Intervention for Early-stage AD Dyads - Adapted for Virtual Delivery | December 12, 2017 | May 2024 |
| NCT06105320 | Recruiting | N/A | COGNIFOOD-Changing the Carbohydrate/Fat-ratio to Prevent Cognitive Decline and Alzheimer Pathology: A Pilot Study | October 2023 | April 2026 |
| NCT06121986 | Recruiting | N/A | A Scalable Nutrition Adherence Intervention | November 30, 2023 | January 2027 |
| NCT05094271 | Recruiting | Phase 1 | Is Obstructive Sleep Apnea Important in the Development of Alzheimer's Disease? | June 30, 2021 | March 20, 2025 |
| NCT03860857 | Recruiting | Phase 3 | Biomarker Exploration in Aging, Cognition and Neurodegeneration | May 1, 2018 | December 22, 2027 |
| NCT06121544 | Recruiting | The Swedish BioFINDER - Preclinical AD Study | April 1, 2022 | December 31, 2025 | |
| NCT06092125 | Recruiting | Clinical Applicantion of Multi-Tracer PET/MR Imaging in Neurological Disorders/Disease | February 1, 2023 | December 2026 | |
| NCT04516057 | Recruiting | Phase 3 | Nabilone for Agitation Blinded Intervention Trial | February 1, 2021 | October 2025 |
| NCT05607732 | Recruiting | N/A | Primary Care Detection of Cognitive Impairment Leveraging Health & Consumer Technologies in Underserved Communities: The MyCog Trial | January 30, 2024 | July 7, 2027 |
| NCT05617014 | Recruiting | Alzheimer's Disease Neuroimaging Initiative 4 | June 9, 2023 | July 31, 2027 | |
| NCT05456503 | Recruiting | Phase 3 | PET Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Using PI-2620 | September 19, 2022 | August 2026 |
| NCT06057909 | Recruiting | A Study of Neurodegeneration and Neuronal Fluctuations in Lewy Body Disease and Alzheimer's Disease | April 5, 2024 | June 2027 | |
| NCT05846984 | Recruiting | N/A | Learning Skills Together Family Caregiver Complex Intervention | January 30, 2024 | April 30, 2027 |
| NCT04780399 | Recruiting | Phase 2 | Efficacy and Safety of Yangxue Qingnao Pills in the Treatment of Mild to Moderate Alzheimer's Disease | November 9, 2021 | December 30, 2024 |
| NCT05345509 | Recruiting | Phase 1/Phase 2 | A Clinical Trial to Access Pharmacokinetic Profiles and Safety of IVL3003. | April 1, 2023 | March 31, 2024 |
| NCT04507815 | Recruiting | N/A | tDCS and Cognitive Training for Mild Cognitive Impairment and Alzheimer's Dementia | September 24, 2020 | September 2024 |
| NCT05800028 | Recruiting | Memory and Social Interactions | March 10, 2023 | December 31, 2026 | |
| NCT03288363 | Recruiting | N/A | Transcranial Direct Current Stimulation and Early Alzheimer's Disease (tDCS-AD) | June 6, 2017 | December 6, 2024 |
| NCT06134180 | Recruiting | N/A | CONFIDENCE-AI Financial Education for Caregivers (CONFIDENCE-AI) | March 23, 2024 | June 30, 2025 |
| NCT05565833 | Recruiting | Phase 2 | Sleep Healthy Using the Internet Mitigating Insomnia to Address Neurocognitive Difficulties (SHUTi MIND) | February 27, 2023 | January 2028 |
| NCT05655793 | Recruiting | The TearAD Study: Tear Biomarkers for Alzheimer's Disease (AD) Screening and Diagnosis | June 9, 2022 | July 1, 2025 | |
| NCT06367426 | Recruiting | Phase 1 | A Phase I Study of DDN-A-0101 in Healthy Volunteers and Elder People | April 2024 | May 2025 |
| NCT05626205 | Recruiting | N/A | Psycho-social Intervention With Paro Robotic Seal Focused on Patients With Dementia | November 5, 2022 | March 30, 2024 |
| NCT04099823 | Recruiting | N/A | MR Evaluation of Cerebrospinal Fluid (CSF) Dynamics | October 31, 2019 | January 2026 |
| NCT05189106 | Recruiting | Phase 1/Phase 2 | Neurodegenerative Alzheimer's Disease and Amyotrophic Lateral Sclerosis (NADALS) Basket Trial | December 5, 2022 | June 1, 2025 |
| NCT03671889 | Recruiting | N/A | ExAblate Blood-Brain Barrier (BBB) Disruption for the Treatment of Alzheimer's Disease | September 28, 2018 | December 2024 |
| NCT06292351 | Recruiting | Phase 2/Phase 3 | DMB-I in the Treatment of Alzheimer Type Dementia | December 27, 2023 | December 21, 2024 |
| NCT05847192 | Recruiting | Tau Networks in Psychotic Alzheimer's Disease | April 13, 2023 | December 31, 2029 | |
| NCT04123314 | Recruiting | Early Phase 1 | Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease | March 24, 2021 | December 30, 2024 |
| NCT04471779 | Recruiting | N/A | Information About Alzheimer's Disease for Latinos in New York City | August 13, 2021 | November 30, 2025 |
| NCT04131491 | Recruiting | N/A | Epilepsy in Alzheimer's Disease: Effect on Disease Progression | February 12, 2020 | September 30, 2023 |
| NCT06148233 | Recruiting | N/A | CSF1R PET Probe [18F]CSF-23 in Alzheimer's Disease Brain Imaging | September 15, 2023 | September 14, 2024 |
| NCT05545657 | Recruiting | Relationship and Central Mechanism Between Diabetes and Cognitive Impairment Based on Simultaneous EEG-fMRI Approach and Peripheral Neuropathology Biomarkers Assay | October 18, 2022 | August 31, 2025 | |
| NCT05640141 | Recruiting | Pre-demential Motoric Cognitive Risk Syndrome in Ageing Subjects | January 26, 2022 | December 30, 2024 | |
| NCT04863495 | Recruiting | Couples Lived Experience | April 19, 2021 | August 1, 2026 | |
| NCT05976659 | Recruiting | N/A | Home-based Neuromodulation to Target Depression And Memory Symptoms in Older Adults | January 24, 2023 | June 30, 2025 |
| NCT05538507 | Recruiting | Phase 2 | Efficacy of Chinese Traditional Medicine "Smart Soup" in Cognition and Behavior Regulation in Alzheimer's Disease | June 1, 2022 | June 2024 |
| NCT04165109 | Recruiting | Trial-Ready Cohort-Down Syndrome (TRC-DS) | June 7, 2021 | December 2025 | |
| NCT03560960 | Recruiting | Early Phase 1 | Multi-Center Development of a Novel Diagnostic Test for Alzheimer's Disease | February 4, 2020 | November 2026 |
| NCT05801380 | Recruiting | Monitoring Drug Efficacy in Patients With Alzheimer's Disease | February 14, 2022 | February 14, 2025 | |
| NCT05107882 | Recruiting | Optina Diagnostics' Cerebral ß-Amyloid Status (CAS) Test | June 7, 2022 | December 2023 | |
| NCT03682081 | Recruiting | N/A | Interventions for Patients With Alzheimer's Disease and Dysphagia | September 25, 2020 | June 30, 2024 |
| NCT05384353 | Recruiting | In Vivo PET of Synaptic Density in Cognitive Disorders | April 11, 2022 | June 2026 | |
| NCT05178992 | Recruiting | Phase 1/Phase 2 | Use of Socially Assistive Robots for Long Term Care Older Adults With Cognitive Impairment and Apathy | September 13, 2021 | July 1, 2025 |
| NCT04575727 | Recruiting | Early Phase 1 | Exploratory Evaluation of [11C]MPC6827 | January 8, 2021 | September 2025 |
| NCT03933696 | Recruiting | N/A | Light, Metabolic Syndrome and Alzheimer's Disease - Aim 2 | January 2, 2019 | May 31, 2025 |
| NCT05776641 | Recruiting | N/A | Gamma Light and Sound Stimulation to Prevent Dementia in Cognitively Normal People at Risk for Alzheimer's Disease | January 10, 2024 | May 2026 |
| NCT04522739 | Recruiting | Phase 4 | Spironolactone Safety in African Americans With Mild Cognitive Impairment and Early Alzheimer's Disease | September 6, 2022 | September 2025 |
| NCT04610944 | Recruiting | N/A | Changing Talk Online Training (CHATO) National Trial | April 26, 2021 | May 31, 2026 |
| NCT04239079 | Recruiting | Autoimmune Features of Neurodegenerative Disorders | May 1, 2019 | June 2024 | |
| NCT05984446 | Recruiting | N/A | Targeting Default Mode Network Dysfunction in Persons at Risk of Alzheimer's Disease With Non-invasive Techniques | December 5, 2019 | December 4, 2024 |
| NCT04337255 | Recruiting | N/A | Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet in Stroke Patients Patients | December 14, 2021 | December 31, 2026 |
| NCT05597410 | Recruiting | Shanghai At Risk for Alzheimer's Disease: a Cohort Study | March 1, 2022 | March 2030 | |
| NCT04949750 | Recruiting | N/A | Efficacy of Paper-based Cognitive Training in Vietnamese Patients With Early Alzheimer's Disease | September 6, 2022 | October 31, 2024 |
| NCT04579120 | Recruiting | Neuroimaging in Healthy Aging and Senile Dementia (HASD_IND) | September 1, 2021 | December 2025 | |
| NCT04696315 | Recruiting | Early Diagnosis of SCD Based on Radiogenomics | January 1, 2021 | December 31, 2025 | |
| NCT02414347 | Recruiting | F 18 T807 Tau PET Imaging of Alzheimer's Disease | October 23, 2014 | December 2024 | |
| NCT05971030 | Recruiting | N/A | Clinical Exploratory Research of Medial Prefrontal Cortex Combined With Dorsolateral Prefrontal Cortex Electrical Stimulation in the Treatment of Alzheimer's Disease | July 30, 2023 | July 30, 2025 |
| NCT03507257 | Recruiting | Longitudinal Early-onset Alzheimer's Disease Study Protocol | April 30, 2018 | May 31, 2024 | |
| NCT03174938 | Recruiting | N/A | The Swedish BioFINDER 2 Study | May 15, 2017 | December 31, 2028 |
| NCT05171725 | Recruiting | Multidisciplinary Expert System for the Assessment & Management of Complex Brain Disorders | April 1, 2021 | September 30, 2024 | |
| NCT06029894 | Recruiting | N/A | Improving Sleep and AD Biomarkers | December 15, 2023 | December 2024 |
| NCT05709210 | Recruiting | N/A | Pilot Study on the Feasibility of Using Smartphone Data as a Diagnostic Marker for Alzheimer's Disease. | July 27, 2023 | February 15, 2024 |
| NCT05372172 | Recruiting | Tennessee Alzheimer's Project | October 27, 2021 | December 31, 2025 | |
| NCT03991624 | Recruiting | N/A | Lack of Decision-making in Patients With Alzheimer's Disease : Functions Involved and the Daily Consequences | September 27, 2019 | October 2025 |
| NCT06116084 | Recruiting | N/A | Randomized Controlled Study Evaluating the Efficacy of Hypnosis in Nuclear Medicine | May 26, 2023 | April 1, 2026 |
| NCT05794451 | Recruiting | Developing an Artificial Intelligence System to Detect Cognitive Impairment | March 20, 2023 | December 31, 2025 | |
| NCT06095063 | Recruiting | N/A | dTMS for Subjective Cognitive Decline | November 15, 2023 | November 15, 2024 |
| NCT04740580 | Recruiting | Early Phase 1 | Glutathione, Brain Metabolism and Inflammation in Alzheimer's Disease | February 15, 2022 | December 31, 2026 |
| NCT05997030 | Recruiting | N/A | Low-Intensity Focused Ultrasound (LIFU) Neuromodulation | October 12, 2023 | September 30, 2025 |
| NCT05667649 | Recruiting | Phase 1 | Autologous Activated Adipose-derived Stem Cells (RB-ADSC) Injected Directly Into the Brain for Mild to Moderate Alzheimer's Disease | August 14, 2023 | March 2025 |
| NCT05021211 | Recruiting | Whole Egg Intake and Choline Concentration in the Aging Brain | June 1, 2021 | December 2023 | |
| NCT03946930 | Recruiting | Cognitive Decline in AD | December 13, 2018 | December 31, 2025 | |
| NCT03896711 | Recruiting | N/A | MEMORI Corps: Activity-based Companion Care for Dementia | March 1, 2022 | September 29, 2024 |
| NCT05138263 | Recruiting | Korean Brain Aging Study for Early Diagnosis and Prediction of Alzheimer's disease2 (KBASE2) | January 1, 2022 | June 2026 | |
| NCT03901261 | Recruiting | N/A | Cohort Study of Adult Patients With Down Syndrome at Risk of Developing Alzheimer's Disease (TriAL21) | April 26, 2019 | March 31, 2023 |
| NCT06096090 | Recruiting | Phase 2 | Phase II Clinical Trial of Interleukin-2 in AD | January 1, 2022 | December 30, 2025 |
| NCT05670912 | Recruiting | Phase 2 | Efficacy and Safety of Wei Li Bai Capsules in the Treatment of Alzheimer's Disease | October 1, 2022 | November 30, 2024 |
| NCT05004987 | Recruiting | Phase 4 | Aβ Dynamics in LLMD | February 4, 2022 | June 2026 |
| NCT05043675 | Recruiting | Early Phase 1 | Clinical Evaluation of [18F]APN-1607 PET Uptake in Alzheimer's Disease Patients | September 10, 2021 | September 10, 2024 |
| NCT05194787 | Recruiting | TAS Test: Online Motor-cognitive Tests for Early Detection of Alzheimer's Disease | March 5, 2021 | December 2030 | |
| NCT05561205 | Recruiting | N/A | rTMS for Apathy Clinical Trial | February 9, 2023 | December 1, 2024 |
| NCT05270408 | Recruiting | N/A | Noninvasive Brain Stimulation in Mild Cognitive Impairment and Dementia | August 8, 2022 | January 2027 |
| NCT04570215 | Recruiting | N/A | Digital Interventions in Neuro-Rehabilitation: Gotcha! | September 17, 2019 | June 30, 2025 |
| NCT05731440 | Recruiting | Fluselenamyl - Beta Amyloid PET Imaging for Alzheimer Disease | November 18, 2022 | November 2025 | |
| NCT05468905 | Recruiting | China Longitudinal Aging and Cognitive Impairment Study | January 10, 2021 | December 2026 | |
| NCT04263194 | Recruiting | N/A | Network-based rTMS in Alzheimer's Disease | March 21, 2019 | March 21, 2024 |
| NCT06223360 | Recruiting | Phase 2 | A Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients With Early Alzheimer's Disease (BenfoTeam) | March 22, 2024 | February 1, 2027 |
| NCT05205980 | Recruiting | N/A | Perturbation Training Reduces Falls in People With AD | April 28, 2023 | June 30, 2024 |
| NCT04616287 | Recruiting | N/A | Self and Autobiographical Memory in Dementia With Lewy Bodies and Alzheimer Disease: a Behavioral and Multimodal Neuroimaging Study | January 25, 2021 | December 2023 |
| NCT06203106 | Recruiting | NYSCF Scientific Discovery Biobank | November 10, 2022 | November 10, 2045 | |
| NCT05077579 | Recruiting | Alzheimer"s Imaging Biomarkers in Obesity | October 18, 2021 | December 31, 2026 | |
| NCT04804241 | Recruiting | Phase 2 | Senicapoc in Alzheimer's Disease | March 18, 2022 | June 2025 |
| NCT04082611 | Recruiting | N/A | The PREVENTION Trial: Precision Recommendations to Optimize Neurocognition | July 12, 2019 | January 2025 |
| NCT05929703 | Recruiting | N/A | Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders | December 4, 2023 | August 2027 |
| NCT05733520 | Recruiting | N/A | I-CARE 2: Mobile Telehealth to Reduce Alzheimer'S-related Symptoms | May 30, 2023 | July 30, 2027 |
| NCT03814603 | Recruiting | The Sleep Amyloid, Slow WAve Race and Ethnicity Study | November 21, 2018 | June 1, 2026 | |
| NCT05063851 | Recruiting | Phase 2 | The Use of Memantine for Prevention of Alzheimer's Disease | October 11, 2021 | December 2025 |
| NCT06072963 | Recruiting | Phase 2 | COMMETS- Combination MCI Metabolic Syndrome | January 30, 2024 | December 1, 2028 |
| NCT05891444 | Recruiting | N/A | Effect of Transcranial Random Noise (tRNS) for Early Alzheimer's Disease | June 1, 2022 | December 1, 2023 |
| NCT05643326 | Recruiting | N/A | At Home Gamma tACS in Alzheimer's Disease (tACS@Home) | June 6, 2022 | June 30, 2024 |
| NCT03638583 | Recruiting | Alzheimer Prevention Trials (APT) Webstudy | December 20, 2017 | April 30, 2026 | |
| NCT04360200 | Recruiting | Cognitive Impairment in Ageing People | April 1, 2020 | December 2040 | |
| NCT05326750 | Recruiting | N/A | Non-invasive Neurostimulation as a Tool for Diagnostics and Management for Neurodegenerative Diseases | November 21, 2022 | July 2032 |
| NCT04840979 | Recruiting | Phase 2 | Discovery and Validation of Genetic Variants Affecting Microglial Activation in Alzheimer's Disease | May 11, 2021 | December 2026 |
| NCT03846492 | Recruiting | N/A | Targeting Brain Physiology to Treat Neuropsychiatric Symptoms of Dementia Using TMS-EEG and tDCS | April 24, 2019 | June 2025 |
| NCT06199193 | Recruiting | N/A | Design of Personalised supplemenTs Based on the Gut micRobiota Through Artificial Intelligence for Alzheimer's Patients | February 1, 2024 | December 31, 2025 |
| NCT05655195 | Recruiting | N/A | Chronic Treatment of Alzheimer's Disease by Gamma Light and Sound Therapy | December 14, 2022 | September 1, 2026 |
| NCT06094192 | Recruiting | N/A | Improving Memory in Alzheimer's Disease With Noninvasive Brain Stimulation | December 20, 2023 | May 31, 2028 |
| NCT06122415 | Recruiting | The Swedish BioFINDER - Memory Clinic Study | December 1, 2022 | December 31, 2026 | |
| NCT05309577 | Recruiting | N/A | Self-Care for Dementia Caregivers | March 7, 2023 | November 1, 2024 |
| NCT06014424 | Recruiting | Phase 2 | Cannabidiol Medication Intervention Trial | September 27, 2023 | December 29, 2026 |
| NCT04129060 | Recruiting | Early Phase 1 | Cholinergic Health After Menopause (CHAMP) | March 15, 2020 | May 31, 2024 |
| NCT05977088 | Recruiting | N/A | Prediction of Effectiveness of rTMS Application in Alzheimer's Patients | February 16, 2022 | May 15, 2025 |
| NCT04389437 | Recruiting | N/A | OCT-Angiography and Adaptive Optics in Patients With Memory Impairment | June 26, 2020 | June 2026 |
| NCT05007353 | Recruiting | N/A | The SINgapore GERiatric Intervention Study to Reduce Cognitive Decline and Physical Frailty (SINGER) Study | August 23, 2021 | January 31, 2026 |
| NCT05582200 | Recruiting | Selective PET Imaging of Astrocytes and Microglia in Alzheimer's Disease | January 20, 2023 | October 31, 2025 | |
| NCT06079827 | Recruiting | Impact of Therapeutic Plasma Exchange on RNA Biomarker Expression Levels in Alzheimer's Patients | March 22, 2022 | September 1, 2025 | |
| NCT05081219 | Recruiting | Phase 2 | SNIFF - Combo INI+EMPA Trial | October 14, 2021 | October 2028 |
| NCT05926011 | Recruiting | N/A | Efficacy of RGn600 in Patients With Mild-to-moderate Alzheimer's Disease | July 24, 2023 | December 2025 |
| NCT02564692 | Recruiting | GeneMatch: A Program of the Alzheimer's Prevention Registry to Match Individuals to Studies Based on Apolipoprotein E (APOE) Genotype | November 2015 | December 2030 | |
| NCT04114994 | Recruiting | Longitudinal Cognitive Assessment by BoCA | October 1, 2019 | October 1, 2029 | |
| NCT05614310 | Recruiting | Detecting Early Alzheimer's Using MR | November 7, 2022 | July 31, 2024 | |
| NCT02638519 | Recruiting | Early Phase 1 | HP Xenon-129 fMRI of Healthy Volunteers and Participants With Alzheimer's Disease | June 27, 2016 | January 28, 2026 |
| NCT05003830 | Recruiting | Application of Multi-probe PET/MR Imaging in the Diagnosis and Evaluation of Alzheimer's Disease | July 1, 2020 | September 1, 2023 | |
| NCT06274528 | Recruiting | Phase 2 | DORA and LP in Alzheimer's Disease Biomarkers | March 11, 2024 | March 11, 2029 |
| NCT05518409 | Recruiting | N/A | Immunohistochemical Study of Neurodegenerative Diseases | April 1, 2022 | December 30, 2023 |
| NCT06168604 | Recruiting | N/A | Evaluating the Efficacy of the Pain Identification and Communication Toolkit | December 14, 2023 | February 2028 |
| NCT03657745 | Recruiting | Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy | January 1, 2018 | December 31, 2025 | |
| NCT03810794 | Recruiting | N/A | Clinical Evaluation on the Therapeutic Effect of Acupuncture Treatment for Alzheimer's Disease | March 1, 2019 | December 30, 2024 |
| NCT06406348 | Recruiting | Phase 1 | A Phase 1 Trial to Assess Safety, Tolerability and Pharmacokinetics of ALIA-1758 in Healthy Participants | May 9, 2024 | January 2025 |
| NCT05374278 | Recruiting | Phase 1/Phase 2 | First-in-Human Evaluation of an Astrocytic Glutamate Transporter (EAAT2) PET Tracer in Dementia | November 2, 2021 | July 1, 2025 |
| NCT06105047 | Recruiting | N/A | Validation of a Remediation Method for Memory Disorders Using Motor and Emotional Encoding in Patients With Alzheimer's Disease | January 22, 2024 | May 2025 |
| NCT05880849 | Recruiting | Phase 1 | Choline Effects - Pre-symptomatic AD | June 26, 2023 | June 2026 |
| NCT05400330 | Recruiting | Phase 1 | Long-Term Follow-up of Gene Therapy for APOE4 Homozygote Alzheimer's Disease | May 8, 2023 | November 2028 |
| NCT02612376 | Recruiting | Rocky Mountain Alzheimer's Disease Center Longitudinal Biomarker and Clinical Phenotyping Study | February 2016 | January 2025 | |
| NCT04100057 | Recruiting | N/A | Sleep Disturbance and Emotion Regulation Brain Dysfunction as Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Dementia | August 31, 2021 | August 30, 2025 |
| NCT05256121 | Recruiting | N/A | HAPPCAP-AD (Human-APPlication Combined Approach for Prevention of Alzheimer's Disease) | June 4, 2019 | December 31, 2024 |
| NCT05318976 | Recruiting | Phase 2 | A Study of XPro1595 in Patients With Early Alzheimer's Disease With Biomarkers of Inflammation | February 28, 2022 | December 31, 2024 |
| NCT04614532 | Recruiting | N/A | Recognizing Pain Intensity in Alzheimer's Disease | November 24, 2021 | January 2025 |
| NCT06210035 | Recruiting | N/A | Effects of Heart Rate Oscillations During Meditation on Plasma Biomarkers of Alzheimer's Disease | January 29, 2024 | December 31, 2024 |
| NCT06385951 | Recruiting | N/A | Spatial Navigation for the Early Detection of Alzheimer's Disease. | March 5, 2024 | October 1, 2028 |
| NCT03503331 | Recruiting | Phase 2 | UAB Alzheimer's Disease Center Core Cohort - Imaging Substudy | April 20, 2018 | April 1, 2026 |
| NCT05478681 | Recruiting | N/A | Home-based Transcranial Direct Current Stimulation (tDCS) for Behavioral Symptoms in Alzheimer's Disease and Related Dementias (ADRD) | April 17, 2023 | September 1, 2024 |
| NCT05200897 | Recruiting | N/A | Transdermal Trigeminal Electrical Neuromodulation on Mild Cognitive Impairment With Insomnia | November 3, 2021 | November 30, 2023 |
| NCT04820335 | Recruiting | N/A | Promoting Independence With Compensatory Cognitive Rehabilitation | February 1, 2022 | December 2025 |
| NCT06372587 | Recruiting | N/A | Next-Generation alzheImer'S Therapeutics | December 19, 2023 | February 28, 2027 |
| NCT05641688 | Recruiting | Phase 3 | [18F]PI-2620 Phase 3 Histopathological Study | December 1, 2022 | March 2026 |
| NCT04308512 | Recruiting | Phase 1/Phase 2 | Care Coordination System for People With Dementia | November 1, 2021 | December 1, 2024 |
| NCT06442852 | Recruiting | Study on the Relationship Between Peripheral Blood miRNA and Risk and Severity of Alzheimer's Disease | April 3, 2021 | December 30, 2026 | |
| NCT06040905 | Recruiting | N/A | Causal Effect of Coenzyme Q10 Nutrition and Cognitive Dysfunction in the Metabolic Storm (Hyperglycemia and Sarcopenia) and Brain-derived Neurotrophic Factor | December 26, 2023 | July 31, 2026 |
| NCT04075435 | Recruiting | Early Phase 1 | Cannabidiol Solution for the Treatment of Behavioral Symptoms in Older Adults With Mild Cognitive Impairment or Alzheimer's Dementia | January 11, 2021 | September 15, 2024 |
| NCT06129838 | Recruiting | Investigation of Inflammation in Alzheimer's Disease and Related Dementias (ADRD) Using [11C]-CS1P1 | May 5, 2023 | May 2026 | |
| NCT04855630 | Recruiting | N/A | Combating Alzheimer's Through Sleep and Exercise | March 1, 2023 | March 1, 2025 |
| NCT03217396 | Recruiting | Biomarkers of Synaptic Damage in Multiple Sclerosis | November 22, 2017 | September 30, 2027 | |
| NCT04971733 | Recruiting | Phase 1/Phase 2 | A Study to Assess Safety and Target Engagement of E2814 in Participants With Mild to Moderate Cognitive Impairment Due to Dominantly Inherited Alzheimer's Disease | June 28, 2021 | July 14, 2025 |
| NCT04692441 | Recruiting | N/A | Apolipoprotein E (APOE) Genotype Effects on Triglycerides and Blood Flow in the Human Brain | May 1, 2021 | December 31, 2025 |
| NCT04935372 | Recruiting | β-AARC: Cohort Study for the Identification of Blood-based Biomarkers in a Population With Subjective Cognitive Decline | May 25, 2021 | December 31, 2025 | |
| NCT05741853 | Recruiting | N/A | Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia | May 1, 2023 | November 30, 2027 |
| NCT03919162 | Recruiting | Phase 2 | A Trial to Evaluate the Efficacy and Safety of PQ912 in Patients With Early AD | November 15, 2021 | September 30, 2024 |
| NCT03649724 | Recruiting | Phase 2 | The LUCINDA Trial: LeUprolide Plus Cholinesterase Inhibition to Reduce Neurological Decline in Alzheimer's | November 27, 2020 | February 2026 |
| NCT06295263 | Recruiting | Application of AI Technology for the Diagnosis and Treatment of Geriatric Diseases | March 1, 2022 | June 29, 2026 | |
| NCT05820919 | Recruiting | N/A | Enhancing Sleep Quality for Nursing Home Residents With Dementia - R33 Phase | September 7, 2023 | May 29, 2027 |
| NCT05723172 | Recruiting | N/A | 40Hz tACS in Treating Cognitive Function and Modulating Neurophysiology of Patients With Alzheimer's Disease | September 1, 2023 | July 31, 2025 |
| NCT05427448 | Recruiting | N/A | Validation of Blood Biomarkers for Alzheimer's Disease | November 24, 2022 | December 31, 2024 |
| NCT05673759 | Recruiting | Event-Related Potential (ERP) Components in Clinical Diagnosis | March 6, 2023 | December 2024 | |
| NCT06366867 | Recruiting | N/A | An Open Platform of Serious Games for Cognitive Intervention | August 3, 2022 | December 1, 2025 |
| NCT06335173 | Recruiting | Phase 2/Phase 3 | A Study to Evaluate Efficacy and Safety of Intravenous ACU193 in Participants With Early Alzheimer's Disease (ALTITUDE-AD) | February 29, 2024 | January 2031 |
| NCT05288842 | Recruiting | Tanycytes in Alzheimer's Disease and Frontotemporal Dementia | September 6, 2022 | October 2026 | |
| NCT05732935 | Recruiting | N/A | Fasting ENHANCE Pilot Study | March 13, 2023 | January 31, 2025 |
| NCT05328115 | Recruiting | Phase 1 | A Study on the Safety, Tolerability and Immunogenicity of ALZ-101 in Participants With Early Alzheimer's Disease | September 30, 2021 | January 15, 2025 |
| NCT06291909 | Recruiting | N/A | Small Steps Towards Improving Activity and Sleep Habits to Decrease the Risk of Dementia | April 3, 2024 | January 2027 |
| NCT05655650 | Recruiting | Identifying Biomarkers in Alzheimer's Disease | September 1, 2018 | December 31, 2030 | |
| NCT05779839 | Recruiting | N/A | A Study of Caregiver Connections Via Technology in Dementia | February 22, 2023 | December 2024 |
| NCT05529706 | Recruiting | N/A | Community-based Brain Health Program to Address Dementia Risk | April 24, 2023 | October 31, 2024 |
| NCT05592366 | Recruiting | N/A | Dementia Care Partner Hospital Assessment Tool | April 2, 2024 | October 2027 |
| NCT05206305 | Recruiting | N/A | Sensory-Evoked Cortical Gamma Oscillation | July 1, 2022 | June 30, 2026 |
| NCT03880240 | Recruiting | Phase 1/Phase 2 | Gamma Induction for Alzheimer's Disease | August 5, 2019 | November 2024 |
| NCT04315337 | Recruiting | N/A | Improving Everyday Task Performance Through Repeated Practice in Virtual Reality. | January 12, 2021 | March 31, 2023 |
| NCT06234930 | Recruiting | N/A | The Feasibility, Safety and Tolerability of VR-based Audiovisual Stimulation | December 14, 2023 | April 15, 2024 |
| NCT05200208 | Recruiting | N/A | Improving Sleep and Cognition in Alzheimer's Disease | July 27, 2022 | August 2024 |
| NCT05939362 | Recruiting | N/A | New Imaging Biomarkers Predictive of MA Progression | October 2, 2023 | January 15, 2027 |
| NCT06249204 | Recruiting | N/A | Patient-Centered Dementia Care Practice Coaching Intervention | December 5, 2022 | June 30, 2025 |
| NCT05466422 | Recruiting | Phase 1 | A Study of MK-2214 in Adults With Mild Cognitive Impairment or Mild-to-Moderate Alzheimer's Disease (MK-2214-002) | September 20, 2022 | May 16, 2025 |
| NCT04576793 | Recruiting | Phase 2 | Longitudinal Imaging of Microglial Activation in Different Clinical Variants of Alzheimer's Disease | November 17, 2020 | May 31, 2025 |
| NCT03840928 | Recruiting | PatientSpot Formerly Known as ArthritisPower | April 1, 2015 | March 1, 2025 | |
| NCT05543681 | Recruiting | Phase 2 | IGC-AD1 Trial on Agitation in Dementia Due to Alzheimer's | October 11, 2022 | June 30, 2025 |
| NCT03739905 | Recruiting | N/A | ExAblate Blood-Brain Barrier Opening for Treatment of Alzheimer's Disease | December 6, 2018 | December 2024 |
| NCT05508789 | Recruiting | Phase 3 | A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5) | October 10, 2022 | April 30, 2027 |
| NCT06400368 | Recruiting | Effect of LEQEMBI on Cerebral and Retinal Amyloid in Mild Cognitive Impairment Due to Alzheimer's Disease | April 24, 2024 | April 2026 | |
| NCT02795052 | Recruiting | N/A | Neurologic Stem Cell Treatment Study | June 2016 | July 31, 2026 |
| NCT05067010 | Recruiting | Finding Retinal Biomarkers in Alzheimer's Disease | June 10, 2021 | December 24, 2024 | |
| NCT05453539 | Recruiting | Phase 1 | Proof-of-concept Study of New Imaging Diagnostic in Patients With Suspected Alzheimer's Disease | November 9, 2022 | January 2025 |
| NCT06375213 | Recruiting | Investigating Neurocognitive Disorders Epidemiology | August 24, 2023 | August 24, 2035 | |
| NCT03703856 | Recruiting | Phase 4 | Biomarker Predictors of Memantine Sensitivity in Patients With Alzheimer's Disease | January 31, 2019 | June 30, 2024 |
| NCT05574634 | Recruiting | N/A | The Role of the Locus Coeruleus in Age-related Distractibility | April 11, 2023 | June 30, 2027 |
| NCT06439992 | Recruiting | Beta Amyloid PET Imaging for Alzheimer Disease With [18F]-Fluselenamyl | November 7, 2023 | November 2025 | |
| NCT05569083 | Recruiting | PRedicting the EVolution of SubjectIvE Cognitive Decline to Alzheimer's Disease With Machine Learning | October 1, 2020 | March 30, 2024 | |
| NCT05925621 | Recruiting | Cognitive Neurology Unit Clinical Registry | July 16, 2023 | June 2028 | |
| NCT06335836 | Recruiting | The Effects of Social Isolation and Social Interaction on the Risk of Dementia Progression and Brain Function in SCD (Subjective Cognitive Decline, SCD) | March 1, 2024 | December 30, 2028 | |
| NCT02811653 | Recruiting | N/A | Motor Slowing and Its Lesion-related Correlates in Alzheimer's Disease | December 1, 2015 | December 2023 |
| NCT04629547 | Recruiting | Phase 2 | Sleep Trial to Prevent Alzheimer's Disease | May 25, 2022 | May 2026 |
| NCT05615233 | Recruiting | N/A | TACAD Program for Asian American Family Caregivers of Persons Living With Alzheimer's | April 5, 2024 | August 31, 2024 |
| NCT04844060 | Recruiting | Cerebro Spinal Fluid Collection (CSF) | February 2010 | December 2030 | |
| NCT06127368 | Recruiting | Phase 1 | Dose-Escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics From Single Dose of Intramuscular (IM) and Subcutaneous (SC) Donepezil (GB-5001) Injections Versus Donepezil Oral Tablet (Aricept®) in Healthy Male Volunteers | January 3, 2024 | January 14, 2025 |
| NCT04800588 | Recruiting | N/A | Computerized Tests of Cognitive Decline in Presymptomatic Alzheimer's Disease | May 5, 2021 | March 31, 2027 |
| NCT06052163 | Recruiting | Phase 2 | Bumetanide in Patients With Alzheimer's Disease | April 10, 2023 | April 15, 2025 |
| NCT06160908 | Recruiting | N/A | Transcranial Near-infrared Light Therapy for Mild-Moderate Alzheimer's Disease | December 12, 2023 | December 31, 2024 |
| NCT05579236 | Recruiting | Cortical Disarray Measurement in Mild Cognitive Impairment and Alzheimer's Disease | September 28, 2022 | April 2025 | |
| NCT05635968 | Recruiting | Phase 2 | The Clinical Trial of Low Dose Irradiation for Alzheimer's Disease | July 15, 2022 | April 15, 2025 |
| NCT03761381 | Recruiting | OCT Angiography and NRAI in Dementia | September 14, 2018 | December 2025 | |
| NCT05647473 | Recruiting | Phase 2 | Efficacy, Safety and Response Predictors of Adjuvant Astragalus for Cognition in Orthostatic Hypotension | February 20, 2024 | May 30, 2025 |
| NCT04784416 | Recruiting | Phase 2 | Transcranial Photobiomodulation for Alzheimer's Disease (TRAP-AD) | April 27, 2021 | November 30, 2025 |
| NCT06099197 | Recruiting | N/A | I-CARE 2: Mobile Telehealth to Reduce Alzheimer'S-related Symptoms in Hispanic Individuals | September 26, 2023 | July 2025 |
| NCT05383183 | Recruiting | Phase 4 | Efficacy and Safety of ChOline ALfoscerate in Patient With Mild to Moderate Alzheimer's Disease | January 20, 2022 | December 9, 2025 |
| NCT04633408 | Recruiting | N/A | Cultural Adaptation of a Behavioral Intervention for Latino Caregivers | July 1, 2020 | June 30, 2024 |
| NCT04335994 | Recruiting | N/A | ENhancing Outcomes in Cognitive Impairment Through Use of Home Sleep ApNea Testing | September 23, 2019 | June 2025 |
| NCT03657732 | Recruiting | The Chinese Familial Alzheimer's Network | January 10, 2005 | January 1, 2038 | |
| NCT03466177 | Recruiting | Multimodal Retinal Imaging in the Detection and Follow-up of Alzheimer's Disease | March 1, 2018 | December 31, 2025 | |
| NCT06104852 | Recruiting | Triage Survey for Neurology Research Eligibility | June 2, 2023 | June 2, 2027 | |
| NCT04452864 | Recruiting | N/A | Tablet-based Cognitive Training | July 1, 2020 | April 1, 2025 |
| NCT05642429 | Recruiting | Phase 1 | Study of AV-1959, an Amyloid Beta Vaccine | February 27, 2023 | November 7, 2026 |
| NCT05468073 | Recruiting | Phase 2 | Therapeutic Evaluation of Low-dose IL-2-based Immunomodulatory Approach in Patients With Early AD | October 11, 2022 | September 1, 2026 |
| NCT05950607 | Recruiting | Phase 4 | Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0 | November 13, 2023 | June 30, 2026 |
| NCT05413655 | Recruiting | Phase 2 | A Study of Oral EX039 in Subjects With Mild Alzheimer's Disease | August 8, 2022 | February 2027 |
| NCT02800395 | Recruiting | N/A | Influence of Oxidative Stress and Nutrition Biomarkers on the Cognitive Decline Evolution in Alzheimer Disease | December 2014 | December 2026 |
| NCT05795634 | Recruiting | N/A | Cognitive Vulnerability to Stress in Individuals at Risk for Alzheimer's Disease | March 1, 2023 | March 1, 2029 |
| NCT03875638 | Recruiting | Phase 2 | Treating Hyperexcitability in AD With Levetiracetam | August 22, 2019 | November 30, 2024 |
| NCT04570085 | Recruiting | Phase 3 | Effect of CAFfeine on Cognition in Alzheimer's Disease | March 1, 2021 | November 2024 |
| NCT05601856 | Recruiting | Gut Microbiome and Blood Indices in Patients With AD and Their Spousal Caregivers | December 15, 2022 | November 30, 2024 | |
| NCT04992195 | Recruiting | Impact of COVID-19 Vaccines on Cerebrovascular Health | July 5, 2021 | December 31, 2026 | |
| NCT05711888 | Recruiting | N/A | Semantic Recognition Task (SRT) in Alzheimer Disease | December 21, 2022 | December 26, 2023 |
| NCT05377060 | Recruiting | N/A | Disclosing Dementia Risk Based on Plasma Phosphorylated Tau | September 1, 2022 | May 31, 2024 |
| NCT06384378 | Recruiting | Phase 2 | Systemic and Central Inflammation in AD | March 17, 2023 | December 30, 2025 |
| NCT05722743 | Recruiting | N/A | Person-Environment Fit for Persons With Dementia | June 14, 2023 | June 15, 2026 |
| NCT03687112 | Recruiting | National Bank Alzheimer | January 1, 2009 | December 31, 2025 | |
| NCT03862222 | Recruiting | Atlas of Retinal Imaging in Alzheimer's Study | December 16, 2019 | June 2025 | |
| NCT05635266 | Recruiting | Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives | October 26, 2021 | October 2025 | |
| NCT05372159 | Recruiting | Vanderbilt Memory and Aging Project | September 17, 2012 | December 31, 2026 | |
| NCT03777722 | Recruiting | N/A | Light and the Effect on Metabolic Syndrome and Alzheimer's Disease | November 1, 2018 | April 30, 2025 |
| NCT05669495 | Recruiting | ANNE Vital Sign System Remote Sleep Assessment | November 10, 2022 | October 2025 | |
| NCT05139290 | Recruiting | N/A | DECIDE: Dyads and Families | July 15, 2022 | December 2026 |
| NCT06179680 | Recruiting | White Matter Hyperintensities in Amnestic Mild Cognitive Impairment or Alzheimer's Disease | July 21, 2022 | December 2026 | |
| NCT05919485 | Recruiting | N/A | The Effects of Specific tDCS on Cognition in MCI | August 1, 2023 | February 15, 2024 |
| NCT05911178 | Recruiting | N/A | Impact of Microglial Activation on Synaptic Density in Alzheimer's Disease | October 18, 2023 | April 17, 2028 |
| NCT03621839 | Recruiting | New CSF Biomarkers for Alzheimer's Disease | July 12, 2013 | December 31, 2050 | |
| NCT04627662 | Recruiting | N/A | Using Technology to Support Care Partners for Persons With Alzheimer's Disease: Tele-STELLA | May 14, 2021 | January 15, 2026 |
| NCT05877196 | Recruiting | N/A | A SMART Trial of Adaptive Exercises to Optimize Aerobic-Fitness Responses | June 22, 2023 | June 30, 2028 |
| NCT04601038 | Recruiting | Phase 2 | Trial of CORT108297 to Attenuate the Effects of Acute Stress in the Allocortex (CORT-X) | June 28, 2021 | January 1, 2027 |
| NCT05984524 | Recruiting | N/A | Gamma-Music Based Intervention for Mild Alzheimer's Disease | July 1, 2022 | June 30, 2027 |
| NCT05361382 | Recruiting | Phase 1 | Head-to-Head Harmonization of Tau Tracers in Alzheimer's Disease | November 23, 2021 | May 31, 2027 |
| NCT04994847 | Recruiting | APOE in the Predisposition to, Protection From, and Prevention of Alzheimer's Disease | May 1, 2021 | June 30, 2026 | |
| NCT05026866 | Recruiting | Phase 3 | A Donanemab (LY3002813) Prevention Study in Participants With Alzheimer's Disease (TRAILBLAZER-ALZ 3) | August 27, 2021 | November 8, 2027 |
| NCT03256539 | Recruiting | N/A | Napping, Sleep, Cognitive Decline and Risk of Alzheimer's Disease | August 12, 2021 | June 2024 |
| NCT06185543 | Recruiting | Phase 2 | A Phase 2, Randomized, Prospective Double-Blind, Single-Center, Placebo-controlled Study to Evaluate Safety, Tolerability, Target Engagement, and Efficacy of PrimeC in Patients With Mild to Moderate Alzheimer's Disease. | November 19, 2023 | November 2025 |
| NCT04436081 | Recruiting | Phase 2 | Effects of THC-Free CBD Oil on Agitation in Patients With Alzheimer's Disease | February 26, 2021 | March 2024 |
| NCT05943054 | Recruiting | N/A | Striatum and Hippocampus on Different Time Scales | January 6, 2023 | March 30, 2026 |
| NCT04575337 | Recruiting | Study on Biomarkers for Early Diagnosis of Alzheimer's Disease | May 28, 2020 | June 30, 2025 | |
| NCT05323812 | Recruiting | Phase 2 | ASURE: Alzheimer Study Using oRal Edaravone | March 1, 2023 | June 2024 |
| NCT03472664 | Recruiting | N/A | Brain Energy for Amyloid Transformation in Alzheimer's Disease Study | July 16, 2018 | April 2026 |
| NCT05853471 | Recruiting | Phase 1/Phase 2 | [18F]MC225-PET in Neurodegenerative Disease | February 1, 2022 | January 1, 2024 |
| NCT05231798 | Recruiting | Phase 2 | Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition | August 19, 2021 | December 31, 2024 |
| NCT03448601 | Recruiting | N/A | Alzheimer's Disease and Precision Medicine Research Among Native People | May 1, 2021 | May 2024 |
| NCT06025877 | Recruiting | Quality Improvement and Clinical Utility PrecivityAD2(TM) Clinician Survey | November 15, 2023 | October 30, 2024 | |
| NCT06170268 | Recruiting | Alzheimer's National Registry for Treatment and Diagnostics(ALZ-NET) | October 20, 2022 | December 2032 | |
| NCT05791552 | Recruiting | N/A | Feasibility of a Method for Analysis of Alzheimer´s Disease Specific Proteins in Nasal Secretion | February 15, 2022 | September 1, 2023 |
| NCT03035851 | Recruiting | N/A | Aerobic Exercise for Older Adults at Increased Risk of Alzheimer's Disease and Related Dementias | January 2017 | January 2025 |
| NCT04274998 | Recruiting | Early Phase 1 | Neuroinflammation Imaging in AD | March 3, 2020 | March 1, 2025 |
| NCT05530590 | Recruiting | N/A | Minnesota Inclusive LTSS for LGBTQ Seniors | January 31, 2024 | July 4, 2026 |
| NCT05641480 | Recruiting | N/A | Technical R&D and Demonstration of Intelligent Medical Care in Alzheimer's Disease's Management | June 3, 2022 | December 9, 2025 |
| NCT06116188 | Recruiting | Brain Insulin Resistance in Mild Cognitive Impairment | October 12, 2023 | October 10, 2025 | |
| NCT05710549 | Recruiting | N/A | Understanding Brain Mechanisms Involved in Autobiographical Memory | April 25, 2022 | August 2025 |
| NCT03799991 | Recruiting | N/A | Vestibular Therapy in Alzheimer's Disease | March 1, 2021 | June 30, 2027 |
| NCT06397339 | Recruiting | N/A | Indian Transforming Alzheimer's Care Training (INTACT) | October 5, 2022 | April 30, 2026 |
| NCT05010603 | Recruiting | Late Onset Alzheimer's Disease | November 15, 2016 | September 2026 | |
| NCT05905822 | Recruiting | DIetary plAnt Extracts, Colonic MicrObes, and Apoe geNetics Interactions stuDy | June 19, 2023 | September 2025 | |
| NCT04404153 | Recruiting | N/A | NeurostImulation for Cognitive Enhancement in Alzheimer's Disease | March 25, 2021 | September 2025 |
| NCT06221202 | Recruiting | N/A | Stories in the Moment: Dance Program for People Living With Dementia | February 10, 2023 | October 31, 2024 |
| NCT05336695 | Recruiting | Phase 1/Phase 2 | Assess Fibrin in Brains With AD/ADRD | March 29, 2022 | September 28, 2024 |
| NCT03670615 | Recruiting | N/A | Using Exercise and Electrical Brain Stimulation to Improve Memory in Dementia | November 28, 2018 | February 2025 |
| NCT05748613 | Recruiting | N/A | Treatment of Stress and Anxiety in MCI/Mild ADRD | November 2, 2023 | January 2028 |
| NCT06245499 | Recruiting | N/A | Aging Brain Care Virtual Program | March 11, 2024 | November 15, 2025 |
| NCT05788848 | Recruiting | Phase 1 | Virtual Reality Cognitive Therapy for Alzheimer's Disease | March 31, 2023 | September 30, 2024 |
| NCT04946916 | Recruiting | N/A | Neurofilament Light Chains and Cognitive Impairment in Chronic Psychiatric Disease | October 22, 2021 | October 22, 2025 |
| NCT06033066 | Recruiting | N/A | Financial Incentives and Recruitment to the APT Webstudy | September 27, 2023 | March 2026 |
| NCT05691842 | Recruiting | N/A | Effectiveness of a High-intensity Interval Exercise Program in People With Alzheimer's | December 20, 2022 | January 2026 |
| NCT04629495 | Recruiting | Phase 2 | Rapamycin - Effects on Alzheimer's and Cognitive Health | August 11, 2021 | December 2024 |
| NCT06247345 | Recruiting | Phase 1 | A Phase Ia/Ib, First-in-human (FIH) Study for Safety, Tolerability, Pharmacokinetics (PK), and Clinical Activity Evaluation of ADEL-Y01 | January 30, 2024 | May 31, 2026 |
| NCT04520698 | Recruiting | N/A | Utilizing Palliative Leaders In Facilities to Transform Care for Alzheimer's Disease | September 8, 2021 | September 2025 |
| NCT04902703 | Recruiting | Phase 2 | Phase II Trial to Evaluate Safety and Efficacy of GM-CSF/Sargramostim in Alzheimer's Disease | June 1, 2022 | July 31, 2025 |
| NCT03381482 | Recruiting | Ectosomes, New Biomarkers of Tau Pathology? | December 20, 2017 | December 2023 | |
| NCT05999084 | Recruiting | Georgia Memory Net Anti-Amyloid Monoclonal Antibody Registry | July 2024 | July 2028 | |
| NCT05905796 | Recruiting | N/A | The Brain Health Study: A Pragmatic, Patient-Centered Trial | December 7, 2022 | September 30, 2025 |
| NCT06120361 | Recruiting | The Swedish BioFINDER - Primary Care Study | January 1, 2020 | December 31, 2028 | |
| NCT05785156 | Recruiting | Diagnostic and Prognostic Value of New Quick Tests of Action Slowing in Stroke and in Cognitive Neurodegenerative Disease | July 16, 2021 | July 2025 | |
| NCT05379348 | Recruiting | Davos Alzheimer's Collaborative Study: Sequential Administration of Digital Testing To Screen For Cognitive Impairment Followed By Blood Based Biomarkers To Assist With Timely Detection And Accurate Diagnosis Of Alzheimer's Disease | March 14, 2022 | December 2023 | |
| NCT03592563 | Recruiting | CUHK Brain Health Longitudinal Study | July 1, 2019 | December 31, 2048 | |
| NCT05322343 | Recruiting | Biobank and Brain Health in Bordeaux. | March 22, 2022 | September 21, 2025 | |
| NCT03702907 | Recruiting | DC Longitudinal Study on Aging and Specimen Bank | January 1, 2007 | January 2027 | |
| NCT02740634 | Recruiting | N/A | Molecular and Structural Imaging in Alzheimer's Disease: A Longitudinal Study | May 2016 | March 2026 |
| NCT03809351 | Recruiting | Phase 1 | UAB Alzheimer's Disease Center Core Cohort - Tau Imaging Substudy | July 8, 2020 | July 8, 2025 |
| NCT03851523 | Recruiting | Longitudinal Study for the Characterization of the Phases of Subjective Perception of Cognitive Decline and Mild Cognitive Impairment of Alzheimer's Disease. | February 12, 2018 | December 31, 2026 | |
| NCT05642351 | Recruiting | Autobiographical Specificity | February 3, 2023 | February 28, 2025 | |
| NCT00064870 | Recruiting | Alzheimer's Disease Genetics Study | June 2002 | July 2026 | |
| NCT05269173 | Recruiting | Phase 2 | Efficacy and Safety of Flos Gossypii Flavonoids Tablet in the Treatment of Alzheimer's Disease | October 29, 2020 | December 30, 2024 |
| NCT04081285 | Recruiting | Epigenetic Biomarkers for Alzheimer's Disease | September 1, 2019 | December 31, 2023 | |
| NCT05077618 | Recruiting | Nalysis of the Periodontal Microbiota in Elderly Subjects With and Without Alzheimer's Disease: a Case Control Study | January 30, 2023 | July 31, 2024 | |
| NCT03278119 | Recruiting | Sleep Aging and Risk for Alzheimer's 2.0 | May 1, 2018 | May 30, 2025 | |
| NCT05068830 | Recruiting | Phase 2 | Safety and Efficacy of Plasma Transfusion From Exercise-trained Donors in Patients With Early Alzheimer's Disease | September 17, 2021 | September 2025 |
| NCT06125951 | Recruiting | Phase 2 | Effect of 10 mg Xanamem on Dementia Due to Alzheimer's Disease | April 12, 2024 | December 2025 |
| NCT04866979 | Recruiting | N/A | Applying Non-invasive Brain Stimulation in Alzheimer's Rehabilitation | April 6, 2021 | January 31, 2024 |
| NCT05892952 | Recruiting | IONA Longitudinal Cohort Study | December 21, 2023 | December 21, 2033 | |
| NCT06170528 | Recruiting | N/A | ARUA-ALZ - Connecting Audio and Radio SensingmSystems to Improve Care at Home for ADRD | November 16, 2022 | December 2024 |
| NCT03628404 | Recruiting | Defining the Genetic Etiology of Alzheimer's Disease in the Faroe Islands | September 1, 2015 | January 1, 2025 | |
| NCT05393388 | Recruiting | Tau Pet Imaging in the Aging Brain Cohort Dedicated to Diversity Study | May 9, 2022 | May 2027 | |
| NCT03860792 | Recruiting | N/A | Therapeutic Diets in Alzheimer's Disease | October 29, 2019 | November 30, 2024 |
| NCT04841135 | Recruiting | N/A | Blood Microbiota Signature of Alzheimer's Disease | June 3, 2021 | January 2026 |
| NCT05516667 | Recruiting | Cohort of Patients With Alzheimer's Disease and Their Families. | April 6, 2023 | January 1, 2027 | |
| NCT05557409 | Recruiting | Phase 3 | A Study to Assess the Efficacy and Safety of AXS-05 in Subjects With Alzheimer's Disease Agitation | September 6, 2022 | June 2025 |
| NCT05531526 | Recruiting | Phase 3 | Phase 3, Double-blind, Randomized, Placebo-controlled Trial to Evaluate the Efficacy and Safety of AR1001 in Participants With Early Alzheimer's Disease (Polaris-AD) | December 23, 2022 | December 2027 |
| NCT05617508 | Recruiting | Phase 2 | N-DOSE AD: A Dose Optimization Trial of Nicotinamide Riboside in Alzheimer's Disease | November 22, 2022 | March 31, 2025 |
| NCT03876314 | Recruiting | N/A | Physical Activity, Alzheimer's Disease and Cognition Relative to APOE Genotype | May 23, 2019 | December 2023 |
| NCT05405075 | Recruiting | Arizona Alzheimer's Disease Research Center (ADRC) | October 1, 2021 | June 30, 2026 | |
| NCT04520412 | Suspended | Phase 3 | A Study of Sodium Oligomannate (GV-971) in Participants With Mild to Moderate Alzheimer's Disease | October 27, 2020 | October 2026 |
| NCT03484143 | Suspended | N/A | Neuro RX Gamma - Pivotal Phase | June 26, 2019 | May 2023 |
| NCT04759365 | Terminated | Phase 1 | Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study of Oral ASN51 in Healthy Subjects and Subjects With Alzheimer's Disease | June 2, 2021 | August 1, 2022 |
| NCT00500500 | Terminated | Phase 2 | Effect of EGb 761® on Patients With Mild to Moderate Alzheimer's Disease | July 2005 | April 2008 |
| NCT03443973 | Terminated | Phase 3 | Safety and Efficacy Study of Gantenerumab in Participants With Early Alzheimer's Disease (AD) | August 22, 2018 | November 28, 2022 |
| NCT04374253 | Terminated | Phase 3 | A Study to Evaluate the Safety, Tolerability, and Efficacy of Long-Term Gantenerumab Administration in Participants With Alzheimer's Disease (AD) | January 26, 2021 | March 6, 2023 |
| NCT02406027 | Terminated | Phase 2 | An Extension Study to Evaluate the Long-Term Safety and Tolerability of JNJ-54861911 in Participants in the Early Alzheimer's Disease Spectrum | July 2, 2015 | June 28, 2018 |
| NCT05028114 | Terminated | Phase 1 | Tricaprilin Liquid Formulation PK Study | August 31, 2021 | July 19, 2022 |
| NCT03371420 | Terminated | Early Phase 1 | PET Imaging of Subjects Using 124I-PU-AD | April 2016 | June 10, 2019 |
| NCT00543322 | Terminated | PET Study of the Nicotinic Receptors in Human | July 2001 | July 2006 | |
| NCT00676143 | Terminated | Phase 3 | Study Evaluating the Safety and Efficacy of Bapineuzumab in Alzheimer Disease Patients | January 2008 | November 2012 |
| NCT02362880 | Terminated | N/A | Study of Genetic Alzheimer's Disease Mutation Carriers in Preclinical Stages of the Disease 18F-Florbetaben Positron Emission Tomography Study | February 2015 | January 2019 |
| NCT00667810 | Terminated | Phase 3 | Study Evaluating The Efficacy And Safety Of Bapineuzumab In Alzheimer Disease Patients | June 2008 | August 2013 |
| NCT00006187 | Terminated | Phase 3 | The Safety and Efficacy of an Investigational Drug in Delaying the Progression of Alzheimer's Disease | June 2005 | |
| NCT04311515 | Terminated | Phase 2 | To Evaluate Safety, Tolerability and Pharmacological Effects of PU AD in Subjects With Mild AD Dementia | June 30, 2020 | November 15, 2022 |
| NCT03047694 | Terminated | N/A | A Lexico-semantic Program on Tactile Tablet for Patients With Alzheimer's Disease | July 15, 2019 | January 15, 2021 |
| NCT05478031 | Terminated | Phase 2 | A Phase 2a Study to Investigate REM0046127 in Mild to Moderate Alzheimer's Disease | June 7, 2022 | June 4, 2024 |
| NCT00322036 | Terminated | Phase 3 | Global Efficacy Study of MPC-7869 to Treat Patients With Alzheimer's | May 2006 | December 2008 |
| NCT00474552 | Terminated | Phase 1 | Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAM-315 | June 2007 | October 2007 |
| NCT01000870 | Terminated | Early Phase 1 | Safety and Efficacy of Positron Emission Tomography Imaging With MNI-513 | October 2009 | September 2010 |
| NCT03819699 | Terminated | Phase 1 | Study With Lu AF20513 in Patients With Mild Alzheimer's Disease (AD) or Mild Cognitive Impairment (MCI) Due to AD | December 12, 2018 | June 27, 2019 |
| NCT03444870 | Terminated | Phase 3 | Efficacy and Safety Study of Gantenerumab in Participants With Early Alzheimer's Disease (AD) | June 6, 2018 | February 17, 2023 |
| NCT04482036 | Terminated | N/A | The MObile AssessMENT of Behavioral and Psychological Symptoms of Dementia in Amnestic MCI and AD (MOMENT) Study | October 23, 2020 | October 4, 2021 |
| NCT00548145 | Terminated | N/A | The Clinical Study of Pitavastatin Treatment for Group of Mild to Moderate Alzheimer's Disease | November 2007 | March 2012 |
| NCT02248116 | Terminated | Phase 2/Phase 3 | Follow-up Trial to Assess the Long-term Safety and Tolerability of Talsaclidine in Patients With Mild to Moderate Dementia of the Alzheimer Type | May 1999 | |
| NCT04010175 | Terminated | N/A | Digital Cognitive Remote Training in Alzheimer's Disease (MA-EIAD) | October 28, 2019 | January 25, 2022 |
| NCT03056495 | Terminated | Phase 1 | Clinical Trial to Determine Tolerable Dosis of Vorinostat in Patients With Mild Alzheimer Disease | September 28, 2017 | March 4, 2024 |
| NCT01028209 | Terminated | Phase 1 | Evaluation of [18F] PBR06 and PET as a Marker of Inflammation in Subjects With Neurological Conditions | November 2009 | September 22, 2010 |
| NCT04678453 | Terminated | Phase 1 | Safety of SNK01 in Subjects With Alzheimer's Disease (ASK-AD) | January 6, 2021 | January 31, 2024 |
| NCT03342326 | Terminated | N/A | Lexical Priming by Music in Alzheimer's Disease and Healthy Aging | April 3, 2018 | May 29, 2019 |
| NCT00544453 | Terminated | Phase 1 | Evaluation of [123I] MNI-308 and SPECT as a Marker of Beta-amyloid Protein Deposition in AD Subjects Compared to HC | October 2007 | July 2008 |
| NCT00612872 | Terminated | Phase 1 | Evaluation of [123I]CLINDE and SPECT as a Marker of Inflammation in Subjects With PD or AD and in Healthy Subjects | January 2008 | November 1, 2009 |
| NCT02440646 | Terminated | Natural History of Coronary Atherosclerosis in Real-World Stable Chest Pain Patients Underwent Computed Tomography Angiography in Comparison With Invasive Multimodality Imaging | May 2015 | August 2022 | |
| NCT03656107 | Terminated | N/A | The Cognition and Flow Study | January 14, 2019 | September 4, 2020 |
| NCT00895895 | Terminated | Phase 2 | Study Comparing 3 Dosage Levels Of SAM-531 In Outpatients With Mild To Moderate Alzheimer Disease | May 2009 | May 2011 |
| NCT03721042 | Terminated | N/A | Demonstrating the Diagnostic Power of an Electronic Nose: Study on Exhaled Air Samples | October 11, 2018 | October 1, 2020 |
| NCT00657813 | Terminated | Phase 1 | Evaluation of [123I] MNI-330 and SPECT as a Marker of Beta-amyloid Protein Deposition | March 2008 | September 30, 2008 |
| NCT02874820 | Terminated | Early Phase 1 | I2PETPG - Imidazoline2 Binding Sites in a Group of Participants Diagnosed With AD | July 2016 | July 2017 |
| NCT02263287 | Terminated | N/A | LESCOD: "Lewy Body Screening in Cognitive Disorders" | October 2014 | August 2017 |
| NCT04795466 | Terminated | Phase 2 | Study of the Efficacy and Safety of Various Anti-inflammatory Agents in Participants With Mild Cognitive Impairment or Mild Alzheimer's Disease | October 28, 2021 | March 7, 2024 |
| NCT01181921 | Terminated | Phase 4 | The CIRCADIAN Study: Evaluation of Modulating Effect of Galantamine on Circadian Rhythm in Patients With Mild to Moderate Alzheimer's Disease | May 2011 | June 2011 |
| NCT04505735 | Terminated | Amyloid Imaging With 11C-PiB in Healthy Aging and Mild Cognitive Impairment | November 22, 2016 | September 23, 2022 | |
| NCT01001637 | Terminated | N/A | Efficacy and Safety of Curcumin Formulation in Alzheimer's Disease | October 2009 | November 2010 |
| NCT02769065 | Terminated | Phase 1 | Study of TAK-071 in Healthy Participants and Participants With Mild Cognitive Impairment/Mild Alzheimer Disease and Relative Bioavailability (BA) and Food Effect of TAK-071 in Healthy Participants | May 5, 2016 | June 8, 2017 |
| NCT00912288 | Terminated | Phase 3 | A Phase 3 Efficacy Study Of Dimebon In Patients With Moderate To Severe Alzheimer's Disease | September 2009 | August 2010 |
| NCT02249351 | Terminated | Phase 2 | Efficacy and Safety of Talsaclidine (Free Base) in Patients With Mild to Moderate Dementia of Alzheimer Type | December 1999 | |
| NCT02351388 | Terminated | N/A | Transcranial Direct Current Stimulation for Depression in Alzheimer's Disease Patient - Preliminary Research | December 2014 | March 15, 2018 |
| NCT03179501 | Terminated | Phase 1 | NP001, Alzheimer's Disease, and Blood Markers of Inflammation | September 1, 2017 | July 31, 2018 |
| NCT04846426 | Terminated | Amyloid Prediction in Early Stage Alzheimer's Disease From Acoustic and Linguistic Patterns of Speech - FUTURE Extension | November 19, 2020 | June 7, 2024 | |
| NCT04592341 | Terminated | Phase 2 | A Study to Evaluate the Pharmacodynamic (PD) Effects of Once Weekly Administration of Gantenerumab in Participants With Early Alzheimer's Disease (AD) | November 18, 2020 | March 15, 2023 |
| NCT03672474 | Terminated | N/A | REGEnLIFE RGn530 - Feasibility Pilot | September 7, 2018 | May 13, 2020 |
| NCT00824967 | Terminated | N/A | Non Pharmacological Management of Behavioural Symptoms in Nursing Home | October 2007 | October 2009 |
| NCT03324711 | Terminated | N/A | Psychometric Validation of the "Antillanisée" Version of the Mini Mental State Examination (MMSEa) | November 15, 2016 | July 2019 |
| NCT01970150 | Terminated | N/A | The Effect of Repeated Transcranial Magnetic Stimulation on Off-line Resting Electroencephalographic Signal in Alzheimer's Disease | February 2014 | April 2015 |
| NCT01400542 | Terminated | Sleep Apnea in Early to Mid-Stage Alzheimer's Disease | December 2010 | June 2014 | |
| NCT02626377 | Terminated | N/A | Multicenter Prospective Cohort of Informal Caregivers in Burgundy and Franche-Comté | October 2015 | May 2019 |
| NCT00605046 | Terminated | Phase 1 | Evaluation of [123I] AV151 and SPECT in Subjects w/ AD in Comparison to Healthy Subjects | August 2007 | June 2008 |
| NCT03790774 | Terminated | N/A | Neurofeedback in Alzheimer's Disease | June 6, 2019 | August 1, 2020 |
| NCT03702816 | Terminated | Phase 2 | The Relationship Between Neuropsychological Testing and MRI, PET and COBRE - Project 1: AIM 2 (GE-180) | December 13, 2018 | September 29, 2019 |
| NCT00998764 | Terminated | Phase 3 | A Long-Term Safety And Tolerability Extension Study Of Bapineuzumab In Alzheimer Disease Patients | December 2009 | November 2012 |
| NCT03052712 | Terminated | N/A | Validation and Standardization of a Battery Evaluation of the Socio-emotional Functions in Various Neurological Pathologies | September 9, 2016 | September 8, 2019 |
| NCT03757910 | Terminated | Early Phase 1 | Brain Imaging in the Diabetes Prevention Program Outcomes Study | October 1, 2019 | January 31, 2023 |
| NCT04951284 | Terminated | Amyloid Prediction in Early Stage Alzheimer's Disease Through Speech Phenotyping - FUTURE Extension | January 21, 2021 | May 28, 2024 | |
| NCT02343757 | Terminated | N/A | Alzheimer's Disease Imaging With PET/MRI - Beta-amyloid | October 2013 | November 9, 2016 |
| NCT00626210 | Terminated | Phase 4 | Modafinil Treatment for Sleep/Wake Disturbances in Older Adults | February 2008 | October 2012 |
| NCT02322021 | Terminated | Phase 2 | Dose-Finding Study To Evaluate Safety, Tolerability, and Efficacy of E2609 in Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (Prodromal Alzheimer's Disease) and Mild to Moderate Dementia Due to Alzheimer's Disease | November 26, 2014 | December 20, 2019 |
| NCT03274817 | Terminated | Phase 1 | A Proof of Concept Study of the Prevention of Mild Cognitive Impairment and Eventual Alzheimer's Disease Using F18 Flutemetamol | June 18, 2009 | September 25, 2019 |
| NCT03998423 | Terminated | Phase 1 | Oral Fecal Microbiota Transplant Feasibility Study in Alzheimer's Disease | November 14, 2019 | July 14, 2020 |
| NCT04121208 | Terminated | Phase 1 | MIcroglial Colony Stimulating Factor-1 Receptor (CSF1R) in Alzheimer's Disease | April 7, 2021 | February 18, 2022 |
| NCT04339413 | Terminated | Phase 3 | A Study to Evaluate the Safety and Tolerability of Long-term Administration of Gantenerumab in Participants With Alzheimer's Disease (AD) | May 22, 2020 | January 4, 2023 |
| NCT00916617 | Terminated | Phase 2 | Study Evaluating The Long-Term Safety And Efficacy Of Subcutaneous Bapineuzumab | June 2009 | September 2012 |
| NCT03227185 | Terminated | N/A | Supporting Episodic Memory With Transcranial Direct Current Stimulation in Healthy Controls and Dementia Patients | October 1, 2017 | October 19, 2019 |
| NCT05491902 | Terminated | Pilot PET Study of Regional Cerebral Protein Synthesis in Alzheimer's | October 9, 2017 | October 15, 2020 | |
| NCT00960531 | Terminated | Phase 2 | A Long Term Extension Study Evaluating ACC-001 With QS-21 in Subjects With Mild to Moderate Alzheimer's Disease | July 2009 | December 2013 |
| NCT02149017 | Terminated | Phase 1/Phase 2 | Phase 1 and Phase 2 Clinical Trials of SNUBH-NM-333(18F) | December 2010 | December 2012 |
| NCT03487380 | Terminated | N/A | Taxonomic and Functional Composition of the Intestinal Microbiome: a Predictor of Rapid Cognitive Decline in Patients With Alzheimer's Disease | September 4, 2017 | June 12, 2023 |
| NCT03393546 | Terminated | N/A | Auricular Point Acupressure to Manage Pain in Patients With Alzheimer's Disease and Related Disorders | August 1, 2018 | March 8, 2022 |
| NCT01669876 | Terminated | Phase 2 | Study to Evaluate Dietary Supplementation With a Version of Anatabloc(R) in Subjects With Alzheimer's Disease | August 2012 | February 2015 |
| NCT03980730 | Terminated | Phase 2 | Study of Azeliragon in Patients With Mild Alzheimer's Disease and Impaired Glucose Tolerance | June 27, 2019 | January 29, 2021 |
| NCT00996918 | Terminated | Phase 3 | A Long-Term Safety And Tolerability Study Of Bapineuzumab In Alzheimer Disease Patients | December 2009 | November 2012 |
| NCT02844855 | Terminated | N/A | Memory for Action in Neurological Patients | December 26, 2016 | February 21, 2020 |
| NCT02388152 | Terminated | Phase 1 | Study to Evaluate the Safety and Tolerability of a New Drug Named Lu AF20513 in Patients With Mild Alzheimer's Disease | March 2015 | July 4, 2019 |
| NCT01815112 | Terminated | N/A | Early Diagnosis of Alzheimer-like Dementia: Benefit of MRI and PET Imaging | February 2008 | April 2014 |
| NCT03858283 | Terminated | N/A | Mindfulness for Alzheimer Caregivers | February 2, 2019 | March 13, 2020 |
| NCT00605059 | Terminated | Phase 1 | Evaluation of [123I] AV94 and SPECT in Subjects With Alzheimer Disease in Comparison to Healthy Subjects | August 2007 | June 2008 |
| NCT03387267 | Terminated | N/A | Videofluoroscopic Swallowing Study (VFSS) | October 24, 2017 | July 23, 2018 |
| NCT05220150 | Terminated | N/A | Discovering FFC-MRI Biomarkers of Alzheimer Disease | October 17, 2017 | September 1, 2021 |
| NCT00739037 | Terminated | Phase 1 | Study Evaluating PAZ-417 in Cerebrospinal Fluid in Subjects With Alzheimer's Disease | August 2008 | December 2008 |
| NCT05216315 | Unknown status | N/A | tDCS and Cognitive Efficiency | July 30, 2020 | June 30, 2023 |
| NCT03969732 | Unknown status | Phase 3 | Multimodal Biomarkers for Diagnosis and Prognosis in CAA | September 27, 2018 | July 31, 2022 |
| NCT00088673 | Unknown status | Phase 3 | Evaluation of 3APS in Patients With Mild to Moderate Alzheimer's Disease | June 2004 | |
| NCT05016427 | Unknown status | Phase 1 | A Study of Possibility of Using Regulatory T Cells(VT301) for Treatment of Alzheimer's Disease | November 1, 2020 | April 1, 2022 |
| NCT01434940 | Unknown status | N/A | Eye Movement Recording as an Early Differential Diagnostic Tool for Alzheimer/Depression | April 2010 | July 2018 |
| NCT01055392 | Unknown status | Phase 2 | Disease-modifying Properties of Lithium in the Neurobiology of Alzheimer's Disease | March 2007 | |
| NCT04466722 | Unknown status | The A-LIST WMM Insights Series | August 15, 2018 | December 31, 2023 | |
| NCT04436341 | Unknown status | Epileptic Activity in Patients With Alzheimer's Disease and Lewy Body Dementia | September 20, 2019 | April 1, 2024 | |
| NCT01128725 | Unknown status | N/A | Truncated and Extended Forms of Amyloid Beta Peptides in Alzheimer's Disease: Genesis, Toxicity and Identification as Biological Markers | September 2010 | December 2012 |
| NCT03038334 | Unknown status | N/A | Magnesium Sulfate for the Improvement of Cognition in Patients With Alzheimer Disease | February 20, 2017 | October 20, 2019 |
| NCT05260151 | Unknown status | Tau Protein and SV2a Imaging in Patients With Tau Protein-related Diseases | November 18, 2020 | December 31, 2022 | |
| NCT03168997 | Unknown status | Phase 4 | Memantine Treatment in Alzheimer's Disease Patients | July 15, 2017 | December 31, 2018 |
| NCT03208491 | Unknown status | N/A | AZ@GAME-Eco: Economic Assessment of Serious Games for the Management of Alzheimer's Disease and Related Disorders | September 30, 2017 | December 30, 2018 |
| NCT03283059 | Unknown status | Phase 3 | Octohydroaminoacridine Succinate Tablet for Mild-to-Moderate Alzheimer's Disease | August 16, 2017 | February 16, 2021 |
| NCT02648906 | Unknown status | Phase 4 | A Clinical Trial for an Evaluation of Choline Alfoscerate and Donepezil for Cognitive Improvements of Patients With Cerebrovascular Injury in Alzheimer Patients | July 2015 | |
| NCT04385225 | Unknown status | N/A | Effect of Hearing Loss and Vestibular Decline on Cognitive Function in Older Subjects | December 16, 2019 | November 2022 |
| NCT03811184 | Unknown status | Validation of a Smartphone Application for the Assessment of Patients With Mild Cognitive Impairment: MemScreen | January 17, 2019 | June 2020 | |
| NCT00094913 | Unknown status | PET Changes in Alzheimer's Disease (AD) | May 2004 | April 2005 | |
| NCT02204969 | Unknown status | Phase 1/Phase 2 | LIWA for Treatment of Alzheimer Patients | January 2015 | December 2015 |
| NCT02829801 | Unknown status | N/A | Evaluation of the Animal Intervention Used as Therapy | March 2, 2016 | May 2, 2019 |
| NCT04628702 | Unknown status | N/A | Playful Multimodal Intervention, Monitoring and Decision Support for Activation of People With Alzheimer's Dementia | February 18, 2020 | April 2022 |
| NCT01095718 | Unknown status | N/A | Comparison of 3 Learning Methods to Improve Independent Activities of Daily Living (IADLs) in Alzheimer Disease | March 2010 | |
| NCT05378659 | Unknown status | Neuroinflammation and Alzheimer's Pathology in POCD | November 1, 2021 | September 30, 2022 | |
| NCT03277573 | Unknown status | Phase 1 | Salsalate in Patients Mild to Moderate Alzheimer's Disease | July 21, 2017 | December 31, 2021 |
| NCT03082755 | Unknown status | Phase 4 | Nighttime Agitation and Restless Legs Syndrome in People With Alzheimer's Disease | July 1, 2017 | March 31, 2023 |
| NCT04100889 | Unknown status | A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Alzheimer's Disease | March 2, 2020 | July 2023 | |
| NCT00094939 | Unknown status | Predictors of Cognitive Decline in Normal Aging | September 2003 | August 2008 | |
| NCT04920786 | Unknown status | Phase 1 | Sequential Dose-escalation Study to Assess the Safety, Tolerability and Pharmacokinetics of TB006 in Healthy Subjects | June 1, 2021 | January 1, 2023 |
| NCT04732182 | Unknown status | N/A | Telerehabilitation Alzheimer's Disease Feasibility (TADF) | February 16, 2022 | February 28, 2023 |
| NCT03472482 | Unknown status | Optical Coherence Tomography in Cerebral Amyloidosis | March 25, 2016 | December 31, 2019 | |
| NCT03352258 | Unknown status | N/A | Effect of Low Dose Radiotherapy on Brain Amyloidosis in the Treatment of Alzheimer's Disease | November 17, 2017 | December 30, 2021 |
| NCT03615027 | Unknown status | N/A | Dementia-specific Intervention of Advance Care Planning | August 3, 2018 | December 31, 2019 |
| NCT01680588 | Unknown status | Phase 2 | Efficacy and Safety of the PET Imaging Agent [18F]NAV4694 in Subjects With Probable Alzheimer's Disease | August 2012 | December 2018 |
| NCT03977025 | Unknown status | Alzheimer Biomarkers on CSF of Elderly Patients Undergoing Surgery | June 11, 2019 | March 2020 | |
| NCT00056329 | Unknown status | Phase 3 | Vitamin E in Aging Persons With Down Syndrome | April 2002 | May 2012 |
| NCT03290274 | Unknown status | N/A | Clinical Trial to Evaluate the Efficacy and Security of Deep Brain Stimulation in Alzheimer´s Disease | March 1, 2017 | December 1, 2019 |
| NCT03954613 | Unknown status | Phase 4 | Evaluation of the Contribution of Regular Cognitive Exercises to Treatment in Patients With Alzheimer's Disease | October 15, 2020 | March 1, 2024 |
| NCT03927040 | Unknown status | N/A | Transcranial Electromagnetic Treatment Against Alzheimer's Disease | April 15, 2019 | March 30, 2020 |
| NCT02208193 | Unknown status | N/A | Alzheimer's Disease, Art and Garden | July 2014 | September 2017 |
| NCT02681822 | Unknown status | Multi-center Imaging Genetics Studies in China | November 2015 | December 2020 | |
| NCT02987842 | Unknown status | N/A | Neurofeedback as a Novel Treatment for Mild Cognitive Impairment & Early Alzheimer's Disease | December 2016 | December 2017 |
| NCT04327778 | Unknown status | N/A | Automate Music Therapy for the Management of Behavioral Disorders in Nursing Homes | April 2020 | August 2021 |
| NCT03672266 | Unknown status | Studies of Brain and Body Interaction | August 1, 2018 | July 1, 2019 | |
| NCT05076331 | Unknown status | Health and Aging Brain Study: Health Disparities Tau Positron Emission Tomography (PET) Scan Study | April 20, 2021 | December 30, 2023 | |
| NCT05004558 | Unknown status | N/A | Effects of Remote-based Resistance Training on Cardiometabolic Risk Factors, Cognitive Function, and Quality of Life in Adults Living With Alzheimer's Disease and/or Related Dementias | September 1, 2021 | June 2022 |
| NCT00192998 | Unknown status | The Serotonergic Transmitter System in Dementia and Affective Disorders | October 2003 | ||
| NCT04663854 | Unknown status | Phase 1 | Mycose AdminiStration for HealIng Alzheimer NEuropathy (MASHIANE) | August 20, 2020 | August 20, 2022 |
| NCT01638884 | Unknown status | N/A | Prospective Memory Imaging | September 2010 | June 2015 |
| NCT04975464 | Unknown status | BRINK (BRain In Kidney Disease) Memory Study 2.0 | November 15, 2011 | December 2021 | |
| NCT04439097 | Unknown status | N/A | Effects of Multicomponent Physical Exercise Program and Mediterranean Diet in Alzheimer's Disease | September 15, 2021 | July 15, 2022 |
| NCT04869904 | Unknown status | Oral Bacterial and Viral Mapping by Dental Plaque in Elderly Patients With and Without Alzheimer's Disease(ORal MICrobiology in Alzheimer's Patients) | June 1, 2021 | December 31, 2021 | |
| NCT04021888 | Unknown status | N/A | The Effects of Exercise Program in Alzheimer's Patients With Mild to Moderate Stage Alzheimer's Disease | July 16, 2018 | July 30, 2020 |
| NCT04509271 | Unknown status | Study on Novel Peripheral Blood Diagnostic Biomarkers for MCI Due to Alzheimer's Disease | October 1, 2020 | September 30, 2022 | |
| NCT03038035 | Unknown status | Phase 2 | The Alzheimer's Disease THErapy With NEuroaid (ATHENE) Study | December 2016 | June 2019 |
| NCT00409279 | Unknown status | N/A | An Innovative Psychosocial Intervention for Adult-Child Caregivers of Parents With Alzheimer's Disease | September 2003 | April 2008 |
| NCT03827733 | Unknown status | Gut Microbiota and Alzheimer's Diseases | February 1, 2018 | December 31, 2022 | |
| NCT04095962 | Unknown status | N/A | Effects of a Multicomponent Exercise Intervention on Physical and Cognitive Function of Older Adults With Dementia | September 1, 2018 | March 2022 |
| NCT05201768 | Unknown status | Determination of Walking, Balance, Fall Risk and Kinesiophobia in Individulas With Alzheimer's Dementation | March 1, 2022 | July 1, 2022 | |
| NCT01297140 | Unknown status | N/A | The PACO Study ("Personnalité Alzheimer COmportement") | January 2009 | November 2015 |
| NCT04823819 | Unknown status | N/A | Assessment of Effectiveness and Safety of Transcranial Magnetic Stimulation (rTMS) Combined With Transcranial Direct Current Stimulation (tDCS) in Dementia Treatment in Alzheimer's Disease | April 1, 2021 | September 30, 2023 |
| NCT04897464 | Unknown status | N/A | Validation Study of a New Digital Treatment Test | June 1, 2021 | May 31, 2022 |
| NCT04146688 | Unknown status | N/A | Nonverbal Communication in Aged People | May 17, 2018 | May 2021 |
| NCT04213391 | Unknown status | N/A | Effects of Sulforaphane in Patients With Prodromal to Mild Alzheimer's Disease | May 10, 2020 | December 1, 2022 |
| NCT04522960 | Unknown status | N/A | Melatonin in Alzheimer's Disease: Effect on Disease Progression and Epileptiform Activity. | October 20, 2020 | July 2023 |
| NCT03151382 | Unknown status | Phase 4 | A Based on PEEG and PET Study of Anxiolytic Treatment to Improve Cognitive Function in Patients With Alzheimer Disease | May 20, 2017 | June 30, 2018 |
| NCT04133454 | Unknown status | Phase 1 | Evaluation of Safety and Tolerability of Libella Gene Therapy for Alzheimer's Disease: AAV- hTERT | October 10, 2019 | January 2021 |
| NCT05433363 | Unknown status | Renji Alzheimer's Disease Neuroimaging Cohort Study | February 14, 2022 | February 2023 | |
| NCT04937959 | Unknown status | Amyloid Prediction in Early Stage Alzheimer's Disease Through Speech Phenotyping - PAST Extension | January 22, 2021 | August 30, 2022 | |
| NCT03650816 | Unknown status | Cerebrovascular Reactivity in Alzheimer's Disease | October 22, 2019 | June 22, 2022 | |
| NCT04025801 | Unknown status | Heidelberg In Vivo Confocal Microscopy to Evaluate the Ocular Surface Disorders of Healthy and Diseased Individuals | July 31, 2019 | June 2020 | |
| NCT03030365 | Unknown status | Orientation in AD Patients: PET-MR Study | February 15, 2017 | February 15, 2020 | |
| NCT02991235 | Unknown status | N/A | Efficacy and Safety of PRJ212 to Improve the Memory of Patients With Mild Severity Alzheimer's Disease | December 2016 | December 2018 |
| NCT02899403 | Unknown status | N/A | Neurophysiological Correlates of Cognitive Tasks in Healthy Volunteers -WP3 P003 | May 19, 2017 | December 2020 |
| NCT04913454 | Unknown status | N/A | CLearing Alzheimer's Disease Molecular Pathology Without Medications | August 1, 2021 | July 31, 2022 |
| NCT04614376 | Unknown status | Alzheimer's and Blood Glucose Levels | November 2020 | March 2022 | |
| NCT03978338 | Unknown status | N/A | A Study to Evaluate the Efficacy and Safety of Brain Polypeptide Solution in Mild Alzheimer's Disease | July 2019 | September 2020 |
| NCT02778581 | Unknown status | N/A | Study to Evaluate the Effect of a Vegetal Oil on Cognitive Impairment | March 2016 | July 2017 |
| NCT01570322 | Unknown status | Determinants of Quality of Life Related to Health in Alzheimer Disease | |||
| NCT04203121 | Unknown status | N/A | The Safety and Scientific Validity of Low-dose Whole Brain Radiotherapy in Alzheimer's Disease. | April 1, 2019 | July 31, 2020 |
| NCT05002699 | Unknown status | Investigating the Impact of Alzheimer's Disease Diagnostics in British Columbia | February 1, 2019 | March 2023 | |
| NCT03153371 | Unknown status | Early-onset Alzheimer's Disease Phenotypes: Neuropsychology and Neural Networks | April 4, 2016 | March 31, 2022 | |
| NCT04265482 | Unknown status | Community-based Cohort of Functional Decline in Subjective Cognitive Complaint Elderly | September 25, 2017 | September 25, 2023 | |
| NCT03865017 | Unknown status | Phase 1/Phase 2 | A Safety and Tolerability Study of GB301 | December 1, 2019 | December 1, 2021 |
| NCT04249869 | Unknown status | Phase 1/Phase 2 | The Efficacy of Traditional Chinese Herbal Medicine for Alzheimer's Disease | February 1, 2020 | December 31, 2020 |
| NCT02518412 | Unknown status | N/A | Transcranial Direct Current Stimulation (tDCS) as a Cognitive Enhancer for Patients With Alzheimers Disease | May 2013 | February 2016 |
| NCT04842552 | Unknown status | Phase 3 | Effect of Hydralazine on Alzheimer's Disease | August 2, 2021 | December 20, 2023 |
| NCT02843906 | Unknown status | N/A | Cognitive, Morphological and Neurobiological Progressive Aspects in Bipolar Disorders in the Elderly: Toward to a Neurodegenerescence Detection? | July 2015 | July 2018 |
| NCT01696591 | Unknown status | The Long-Term Safety and Efficacy Follow-Up Study of Subjects Who Completed the Phase I Clinical Trial of Neurostem®-AD | March 2012 | September 2013 | |
| NCT01255046 | Unknown status | Phase 2 | Study of STA-1 as an Add-on Treatment to Donepezil | December 2015 | |
| NCT03939286 | Unknown status | N/A | Multimodal Imaging Study on Physical Activity in Patients With Alzheimer's Disease | April 8, 2019 | October 2021 |
| NCT02578303 | Unknown status | N/A | Association Between Cerebral Arterial Vascular Flow and Sleep Apnea in Neurodegenerative Alterations | May 2015 | January 1, 2022 |
| NCT05366023 | Unknown status | N/A | Elucidating the Necessary Active Components of Training | February 21, 2022 | February 2024 |
| NCT02841605 | Unknown status | N/A | Enteric Nervous System in Alzheimer Disease | October 2016 | May 2019 |
| NCT05251649 | Unknown status | N/A | Transcranial Alternating Current Stimulation Combined With 40Hz Sound Stimulation for Treatment Alzheimer's Disease | December 23, 2021 | January 2023 |
| NCT04388982 | Unknown status | Phase 1/Phase 2 | the Safety and the Efficacy Evaluation of Allogenic Adipose MSC-Exos in Patients With Alzheimer's Disease | July 1, 2020 | August 2022 |
| NCT04928690 | Unknown status | Prediction of Amyloid and Mild Cognitive Impairment in Early Stage Alzheimer's Disease From Remote Speech Phenotyping | June 20, 2021 | August 30, 2022 | |
| NCT01782248 | Unknown status | N/A | Self-consciousness in Dementia | March 13, 2013 | March 12, 2022 |
| NCT03896698 | Unknown status | N/A | Feasibility Study of Transcranial Ultrasound Stimulation on Alzheimer's Disease Patients | August 23, 2019 | June 30, 2021 |
| NCT03900936 | Unknown status | Detecting Dementia Earlier | January 19, 2017 | August 30, 2021 | |
| NCT04294888 | Unknown status | N/A | TMS in Preclinical and Prodromal AD: Modulation of Brain Networks and Memory | March 2, 2020 | March 1, 2024 |
| NCT01839422 | Unknown status | N/A | Imaging of New Learning in Severe Alzheimer's Disease Patients | January 2012 | |
| NCT00438724 | Unknown status | N/A | Couples Coping With Alzheimer's Disease | November 2004 | November 2007 |
| NCT03676881 | Unknown status | Longitudinal Validation of a Computerized Cognitive Battery (Cognigram) in the Diagnosis of Mild Cognitive Impairment and Alzheimer's Disease | September 4, 2018 | December 2021 | |
| NCT03136679 | Unknown status | Discovery of Novel Biomarkers That Will Lead to the Early Detection of Alzheimer's Disease | March 22, 2017 | December 31, 2022 | |
| NCT03645993 | Unknown status | Early Onset Alzheimer's Disease Genomic Study | June 16, 2017 | June 16, 2022 | |
| NCT03123224 | Unknown status | N/A | The COACH Project: Combined Online Assistance for Caregiver Health | August 2015 | July 2018 |
| NCT03289377 | Unknown status | N/A | NRC:Improving Healthcare for Cognitively Impaired Elders and Their Caregivers | February 1, 2018 | October 2018 |
| NCT04524338 | Unknown status | N/A | Longitudinal Study Examining At-Home tDCS | October 31, 2020 | October 31, 2022 |
| NCT04604600 | Unknown status | Phase 3 | Multimodal Biomarkers for Diagnosis and Prognosis in VCI | September 3, 2020 | July 31, 2023 |
| NCT05443308 | Unknown status | Cerebral Vascular Reserve in Small Vessel Disease and Alzheimers Disease | June 21, 2022 | April 15, 2023 | |
| NCT05164536 | Unknown status | Phase 1 | Plasma P-tau2017 and Quantitative Amyloid PET Imaging | August 27, 2021 | September 1, 2022 |
| NCT02299154 | Unknown status | N/A | Memory Problems Perceptions Among Patients and Accompaniers During Diagnosis Process : | December 2014 | November 2017 |
| NCT04280861 | Unknown status | N/A | Multicomponent Intervention in Caregivers on Quality of Life of People With Dementia: a Clinical Trial | February 2, 2020 | December 21, 2021 |
| NCT03038282 | Unknown status | N/A | Effects of Chromium on Insulin Resistance in Alzheimer Disease Patients | February 20, 2017 | October 20, 2019 |
| NCT03672448 | Unknown status | The China Longitudinal Aging Study of Cognitive Impairment | September 1, 2018 | November 30, 2023 | |
| NCT02802371 | Unknown status | N/A | Pharmaceutical Collaborative Care Integrated to a Multidisciplinary Psychosocial Program | August 2016 | February 2020 |
| NCT04865172 | Unknown status | ECOCAPTURE for the Assessment of Apathy Under Real-life Conditions | September 2021 | September 2023 | |
| NCT03784183 | Unknown status | N/A | Neuropsychological and Neurophysiological Effects of Cognitive Stimulation in Patients With Alzheimer's Disease and Mild Cognitive Impairment | September 27, 2018 | October 1, 2020 |
| NCT03352739 | Unknown status | N/A | Fornix and NbM as Targets of Stimulation In Alzheimer's Disease | December 1, 2017 | December 1, 2020 |
| NCT02288000 | Unknown status | Phase 1 | Prediction of Cognitive Properties of Memantine for Neurodegenerative Diseases | September 14, 2016 | September 2020 |
| NCT02195596 | Unknown status | N/A | Effects of Exercise on Cognitive Performance of Patients With Alzheimer-type Dementia. Pilot Study. | April 2013 | December 2015 |
| NCT03838952 | Unknown status | N/A | The Efficacy of Traditional Chinese Herbal Medicine for Dementia | February 11, 2019 | December 31, 2020 |
| NCT04526262 | Unknown status | N/A | Assessment of Initial Efficacy and Safety of High Intensity Focused Ultrasound 'ExAblate 4000 Type 2' for Blood Brain Barrier Disruption in Patients With Alzheimer's Disease | April 10, 2020 | December 2020 |
| NCT02134041 | Unknown status | Amyloid Accumulation After Mild Traumatic Brain Injury | October 2012 | September 18, 2019 | |
| NCT01378026 | Unknown status | Study of the Role of G72 in Amyotrophic Lateral Sclerosis: Biomarker Discovery and Mechanism Investigation | January 2012 | ||
| NCT01417130 | Unknown status | Follow-up Study of the Alzheimer's Disease Anti-Inflammatory Prevention Trial | August 2009 | August 2012 | |
| NCT05326009 | Unknown status | A Direct Comparative Study of Tau Tracer in Patients With Alzheimer's Disease | November 20, 2021 | May 31, 2023 | |
| NCT04851496 | Unknown status | Amyloid Prediction in Early Stage Alzheimer's Disease From Acoustic and Linguistic Patterns of Speech - PAST Extension | November 19, 2020 | August 30, 2022 | |
| NCT05189132 | Unknown status | Periodonitis and Alzheimer's Disease | September 1, 2022 | January 2023 | |
| NCT03308032 | Unknown status | N/A | Self-Directed Online Training for Chinese Caregivers | September 1, 2016 | July 30, 2018 |
| NCT03270137 | Unknown status | N/A | Repetitive Transcranial Magnetic Stimulation in Patients With Alzheimer Disease | March 10, 2016 | August 31, 2017 |
| NCT04559789 | Unknown status | N/A | Reducing Dementia Risk With Digital Health Coaching | January 4, 2021 | January 30, 2024 |
| NCT02663531 | Unknown status | N/A | Retinal Neuro-vascular Coupling in Patients With Neurodegenerative Disease | September 27, 2016 | September 30, 2023 |
| NCT00599469 | Unknown status | Phase 1 | Far Infrared Treatment for Alzheimer's Disease | February 2008 | April 2009 |
| NCT03295110 | Unknown status | N/A | Connected Solution of Assistance Dedicated to Caregivers and People With Alzheimer's Disease or Related Diseases | February 13, 2018 | September 2019 |
| NCT02840045 | Unknown status | N/A | Development of a New Neuroimaging Method Aimed to Differentiate Mnesic Abilities of Alzheimer and Depressed Patients | February 20, 2015 | August 20, 2018 |
| NCT05119114 | Unknown status | Volumetric Magnetic Resonance Imaging in Dementia | December 2021 | December 2023 | |
| NCT02686554 | Unknown status | Identification of Proteostasis-related Biomarkers in Alzheimer´s Dementia | January 2016 | December 2022 | |
| NCT03644043 | Unknown status | Evidence Amyloid Scan EEG Study | July 20, 2018 | November 30, 2020 | |
| NCT03115814 | Unknown status | Deep Brain Stimulation for Treatment of Severe Alzheimer's Disease | April 17, 2017 | June 2019 | |
| NCT01314638 | Unknown status | Study of Adherence and Effects of Balance Exercices (SIEL BLEU Associatio) | May 2010 | June 2011 | |
| NCT05055895 | Unknown status | Association of Anticholinergic Burden With Onset of Delirium in Older Adults With Alzheimer Dementia: | January 1, 2005 | December 2022 | |
| NCT05239390 | Unknown status | Phase 2 | SCI-110 for Alzheimer Disease and Agitation | December 29, 2021 | June 29, 2023 |
| NCT04635540 | Unknown status | N/A | Decreased Empathy and Emotion Recognition in Patients With Neurodegenerative Disease | July 22, 2019 | July 2022 |
| NCT05009524 | Unknown status | N/A | The Interactive Physical and Cognitive Exercise System (v3) for Mild Cognitive Impairment (MCI) | August 23, 2021 | August 31, 2022 |
| NCT01874418 | Unknown status | N/A | Biomarker Study to Diagnose Alzheimer's Disease | March 2012 | February 2015 |
| NCT03959124 | Unknown status | N/A | Deep Brain Stimulation for Alzheimer's Disease | April 6, 2020 | September 30, 2021 |
| NCT02835716 | Unknown status | Pre-Clinical (Alzheimers) Diagnosis PCD = Optimum Outcomes OO | September 2016 | September 2020 | |
| NCT04132193 | Unknown status | Processing of Music in Alzheimer Patients | October 2019 | May 2021 | |
| NCT04220593 | Unknown status | N/A | Effects of Transcranial Direct Current Stimulation Associated With Cognitive Training in Alzheimer's Disease | November 25, 2019 | December 1, 2020 |
| NCT03661034 | Unknown status | N/A | Study of Tolerability, Safety and Efficacy of Sensory Stimulation at Multiple Dose Levels to Improve Brain Function (Etude Study) | May 31, 2018 | March 1, 2022 |
| NCT04228666 | Withdrawn | Phase 1/Phase 2 | A Clinical Trial to Determine the Safety and Efficacy of Hope Biosciences Autologous Mesenchymal Stem Cell Therapy (HB-adMSCs) for the Treatment of Alzheimer's Disease | March 1, 2020 | February 1, 2022 |
| NCT04064021 | Withdrawn | N/A | Acupuncture Treatment for Improving Alzheimer's Dementia | January 1, 2025 | March 31, 2027 |
| NCT04096261 | Withdrawn | The Importance of Sleep Quality and the Blood-brain Barrier in Cognitive Disorders and Alzheimer's Disease | September 12, 2019 | December 31, 2019 | |
| NCT03816228 | Withdrawn | Imaging of Brain Structural/Functional Connectivity and Amyloid and Tau Lesions in APOE4 Carriers. | January 2022 | October 11, 2022 | |
| NCT02664571 | Withdrawn | N/A | Florbetaben as an Amyloid Plaque Marker in Elderly Patients With Focal or Disseminated Superficial Hemosiderosis | July 2020 | July 2021 |
| NCT06220292 | Withdrawn | N/A | Intermittent Oral-esophageal Tube Feeding in Alzheimer's Patients With Dysphagia | January 30, 2024 | August 15, 2024 |
| NCT04019665 | Withdrawn | N/A | Self-screening of Cognitive Impairment in Primary Care | May 27, 2020 | December 1, 2020 |
| NCT04440891 | Withdrawn | N/A | Application of TMS Coupled With VR for Slowing the Rate of Cognitive Decline in Patients With Alzheimer's Disease | October 3, 2019 | November 2, 2021 |
| NCT04263519 | Withdrawn | Phase 2 | A Pilot Open Labeled Study of Tacrolimus in Alzheimer's Disease. | December 1, 2021 | January 1, 2023 |
| NCT04205539 | Withdrawn | Phase 1 | Lymphatic System Health in Alzheimer's Disease | December 10, 2021 | December 2023 |
| NCT03204604 | Withdrawn | N/A | The Brain Ketone Body Challenge Imaging Study | August 8, 2016 | March 2019 |
| NCT05728736 | Withdrawn | Phase 2 | Acute Effect of Lemborexant on CSF Amyloid-Beta and Tau | March 1, 2023 | October 4, 2023 |
| NCT05321498 | Withdrawn | Phase 2 | Study to Assess the Efficacy of XPro1595 in Patients With Mild Cognitive Impairment With Biomarkers of Inflammation | June 2023 | October 26, 2023 |
| NCT04041895 | Withdrawn | Detecting Probable Alzheimer's Disease From Speech Using Linguistical Analysis | August 13, 2018 | August 2020 | |
| NCT04942184 | Withdrawn | N/A | STRATEGIES to Improve Memory in Alzheimer's Disease | October 2022 | June 2023 |
| NCT03939780 | Withdrawn | N/A | Tau Tracer Comparison in Healthy Controls and Alzheimer's Disease Patients | January 2020 | April 2023 |
| NCT04255329 | Withdrawn | N/A | Non Verbal Communication and Dementia | February 2020 | September 27, 2021 |
| NCT03149380 | Withdrawn | N/A | Effectiveness of Alzheimer's Universe (Www.AlzU.Org) on Knowledge and Behavior | January 2017 | October 2024 |
| NCT01822951 | Withdrawn | Phase 4 | Cerebrolysin Compared to Donepezil in Patients With Mild to Moderate Dementia of Alzheimer's Type (DAT) | December 2016 | |
| NCT04901494 | Withdrawn | SSRI's and the Rate of Progression From MCI to Dementia | September 1, 2021 | October 6, 2023 | |
| NCT06257563 | Withdrawn | N/A | Toolkit for Experiential Well-beiNg in Dementia (TEND) | February 2024 | April 2024 |
| NCT02707978 | Withdrawn | Phase 2 | F 18 T807 Tau PET Imaging of Frontotemporal Dementia (FTD) | September 30, 2017 | December 30, 2020 |
| NCT00743743 | Withdrawn | Phase 3 | Pilot Study of the Effects of Resveratrol Supplement in Mild-to-moderate Alzheimer's Disease | September 2008 | December 2010 |
| NCT03472183 | Withdrawn | N/A | Exploration of the Enteric Nervous System in Alzheimer Disease | April 26, 2018 | September 18, 2019 |
| NCT01870453 | Withdrawn | Differential Effects of Various Anesthetic Agents on Cognitive Function in Patients With Alzheimer's Disease | October 2013 | December 2018 | |
| NCT04514328 | Withdrawn | N/A | Highlighting the Benefits of Therapeutic Gardens in Alzheimer's Disease by 18F-FDG Cerebral PET /CT | August 2, 2022 | January 2, 2023 |
| NCT05921929 | Withdrawn | Phase 1 | First-In-Human (FIH), Single Ascending Dose (SAD) Study of FluoroEthylNorMemantine (FENM) | May 2, 2024 | May 2, 2024 |
| NCT04282798 | Withdrawn | N/A | Racial Variation in Response to Music Interventions for People With Alzheimer's Dementia | June 2020 | March 2021 |
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- HPO alt_id (Human Phenotype Ontology)
- HP:0006878
- HPO alt_id (Human Phenotype Ontology)
- HP:0007213
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0002511
- ICD10 preferred id (Insert disease from ICD10)
- D0005318
- ICD10 class code (Insert disease from ICD10)
- G30
- MeSH unique ID (MeSH (Medical Subject Headings))
- D000544