Respiratory Depression

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Information
Disease name
Respiratory Depression
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04011163 Active, not recruiting Phase 2/Phase 3 Vital Signs-Integrated Patient-Assisted Intravenous Opioid Analgesia for Post Surgical Pain March 31, 2021 December 31, 2025
NCT03441282 Active, not recruiting Precision Medicine in Anesthesia: Genetic Component in Opioid-induced Respiratory Depression October 30, 2018 December 31, 2024
NCT02804022 Active, not recruiting Phase 2 Vital-signs-integrated Patient-assisted Intravenous Opioid Analgesia December 29, 2016 December 31, 2024
NCT06374589 Active, not recruiting N/A Closed-Loop O2 Use During High Flow Oxygen Treatment Of Critical Care Adult Patients (CLOUDHFOT) March 21, 2024 December 30, 2024
NCT01362270 Completed N/A Acupuncture for Sedation in the Intensive Care Unit (ICU) July 2011 July 2015
NCT01740453 Completed Phase 4 Effect of Interscalene Block on Ventilatory Function January 2012 March 2012
NCT03996694 Completed Phase 1 Single Dose Crossover Study to Compare the Respiratory Drive After Administration of Belbuca, Oxycodone and Placebo. July 23, 2019 October 27, 2019
NCT00544947 Completed Observation of Respiration Following Regional Anaesthesia With Intrathecal Opioids for Caesarean Section October 2007 July 2008
NCT00696137 Completed Phase 3 Long-term Extension Study of BEMA™ Fentanyl June 2008 July 2009
NCT00875134 Completed Phase 1/Phase 2 Testing of the Apnea Prevention Device March 2009 March 2010
NCT02417038 Completed Postoperative Respiratory Monitoring After Neuraxial Opioid Administration for Cesarean Delivery April 2015 April 15, 2016
NCT02473354 Completed Phase 1 Predictors of Opioid-Induced Respiratory Depression (OIRD) April 2015 April 29, 2018
NCT02481570 Completed N/A Anesthetic Optimization in Scoliosis Surgery November 2015 August 15, 2017
NCT02707003 Completed Clinical Utility of Capnography in the PACU( Post-anaesthesia Care Unit) February 2016 June 15, 2018
NCT02811302 Completed N/A PRediction of Opioid-induced Respiratory Depression In Patients Monitored by capnoGraphY April 7, 2017 May 7, 2018
NCT02885948 Completed Phase 4 The Use of Low Dose Prophylactic Naloxone Infusion to Prevent Respiratory Depression With Intrathecal Morphine. April 2016 December 2017
NCT02903173 Completed An Observational Study of Post-cesarean Delivery Respiratory Patterns Using a Non-invasive Minute Ventilation Monitor (Exspiron ™ System) February 2015 June 27, 2018
NCT02907255 Completed N/A Vital Sign Monitoring With Continuous Pulse Oximetry and Wireless Clinician Notification After Surgery October 2010 December 31, 2019
NCT02987985 Completed Phase 3 Efficacy of Opioid-free Anesthesia in Reducing Postoperative Respiratory Depression in Children Undergoing Tonsillectomy October 15, 2017 December 20, 2020
NCT03050983 Completed Determination of the Clinical Impact of Continuous Surveillance Monitoring (SM) and Utility of IPI. February 15, 2017 September 10, 2020
NCT03141294 Completed N/A Reformative Versus Single Step Dilation Percutaneous Dilatational Tracheostomy July 1, 2012 February 15, 2017
NCT03938259 Completed Effect of Opioids on Ventilation in Children With Obstructive Sleep Apnea July 1, 2019 August 30, 2020
NCT00345384 Completed Phase 1/Phase 2 Dexmedetomidine for the Control of Post-Operative Pain in Thoracotomy Patients May 2008 January 2010
NCT04017702 Completed Detection of Postoperative Respiratory Depression in High Risk Patients Utilizing Minute Ventilation Monitoring June 20, 2018 February 20, 2020
NCT04301895 Completed Phase 1 Pupillary Unrest in Ambient Light, and Relationship to Opioid-Induced Respiratory Depression April 30, 2019 September 3, 2019
NCT05465226 Completed Phase 4 Oliceridine in Patients With Acute Burn Injuries April 1, 2023 October 24, 2023
NCT06083272 Completed VitalThings Guardian Contactless Monitoring November 15, 2023 November 28, 2023
NCT01843933 Completed N/A Detecting Post-Operative Respiratory Depression in Children June 2013 December 2014
NCT01869582 Completed N/A Safer Births - Reducing Perinatal Mortality March 2013 April 2018
NCT01874834 Completed N/A Cardiopulmonary Responses to Exposure to Ozone and Diesel Exhaust August 2010 January 2013
NCT01969227 Completed N/A The Effects of Ketamine on Respiratory Stimulation and Transpulmonary Pressures January 2014 December 2022
NCT02133586 Completed N/A Effects of Sequential Exposure to Nitrogen Dioxide and Ozone in Healthy Adult Human Volunteers. January 2014 January 2016
NCT06137638 Not yet recruiting Phase 2 ENA-001 for Post Operative Respiratory Depression (PORD) March 15, 2024 September 15, 2025
NCT06064409 Not yet recruiting Optimal Timing and Failure Prediction of High Flow Nasal Cannula Oxygen Therapy in Emergency Department: Prospective Observational Single Center Study November 1, 2023 March 2025
NCT05391555 Recruiting Phase 2/Phase 3 Pupillary Unrest as an Indicator of Central Opioid Effect in Subjects 40-60 Years of Age October 1, 2022 August 31, 2023
NCT01784991 Terminated N/A Study of Respiratory Depression When Using a Hydromorphone Pain Protocol December 2011 April 16, 2014
NCT01181843 Terminated Incidence of Respiratory Depression in Cesarean Section July 2010 June 2014
NCT03151226 Terminated N/A OSA Screen Negative With Spinal Duramorph August 3, 2015 October 1, 2015
NCT02760927 Terminated N/A Assessment of a Oral Endotracheal Tube Fastener on Patients Intubated With Oral Endotracheal Tubes March 2016 May 2016
NCT01714791 Terminated N/A Effects of Osteopathic Treatment on Pulmonary Function After Coronary Artery Bypass Graft Surgery January 2010 December 2017
NCT03775122 Unknown status N/A TAES Improve the Function of Respiration and Circulation on Elderly Patients Undergoing Colonoscopy Procedure February 15, 2019 April 30, 2019
NCT03948880 Unknown status Incidence OIRD Medical and Trauma Patients July 29, 2019 November 29, 2019
NCT01482078 Unknown status Magnesium for Neonatal Neuroprotection and Mothers January 26, 2012 July 2019
NCT01517217 Unknown status N/A Effect of Postoperative Girdle Following Abdominal Surgery on Pulmonary Function, Mobilisation and Postoperative Pain April 2011 June 2012
NCT04046068 Unknown status Multimodal Perioperative Pain Management: ComfortSafe Program May 11, 2020 September 2021
NCT05235503 Unknown status Phase 4 Influence of Δ9-tetrahydrocannabinol (THC) on Oxycodone Induced Ventilatory Depression in Healthy Volunteers December 9, 2021 June 2023
NCT02819661 Unknown status N/A Respiratory Depression in Women With BMI≥30 Underwent Spinal Anesthesia With Intrathecal Morphine in Elective C-section May 1, 2018 June 30, 2019
NCT04495452 Withdrawn Precision Medicine in Anesthesia June 10, 2024 September 1, 2025
NCT03647696 Withdrawn Incidence of Opioid-Induced Respiratory Depression in Medical and Trauma Patients August 30, 2018 August 30, 2018