Hemoglobinuria, Paroxysmal

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Information
Disease name
Hemoglobinuria, Paroxysmal
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT00438789 Approved for marketing The Paroxysmal Nocturnal Hemoglobinuria Early Access Treatment Protocol
NCT00122304 Completed Phase 3 Study of Safety in Hemolytic Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients Treated With Eculizumab December 2004 November 2006
NCT00122330 Completed Phase 3 Study Using Eculizumab in Transfusion Dependent Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients October 2004 January 2006
NCT00152139 Completed Phase 3 Stem Cell Transplantation for Patients With Hematologic Malignancies May 2002 January 2009
NCT00098280 Completed Phase 3 Eculizumab to Treat Paroxysmal Nocturnal Hemoglobinuria December 2004 February 2006
NCT00721864 Completed The Molecular Biology of Paroxysmal Nocturnal Hemoglobinuria (PNH) May 2006 December 2010
NCT00867932 Completed Phase 4 Eculizumab Pharmacokinetics/Pharmacodynamics Study in Pediatric/Adolescent Paroxysmal Nocturnal Hemoglobinuria (PNH) October 2, 2009 May 12, 2011
NCT00975975 Completed Phase 2 Basiliximab #2: In-Vivo Activated T-Cell Depletion to Prevent Graft-Versus_Host Disease (GVHD) After Nonmyeloablative Allotransplantation for the Treatment of Blood Cancer September 2009 November 2013
NCT00997386 Completed Phase 2 Reduced Intensity Allogeneic PBSCT to Treat Hematologic Malignancies and Hematopoietic Failure States September 2009 January 2016
NCT00618969 Completed Phase 2 Peripheral Blood Stem Cell Transplantation (PBSCT)From Haploidentical Related Donors February 2008 February 2016
NCT00315419 Unknown status Identifying Characteristics of Bone Marrow Failure Syndromes April 2006 July 2009
NCT01642979 Unknown status Phase 2 Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Classic Paroxysmal Nocturnal Hemoglobinuria July 2012 July 2017
NCT01760096 Unknown status Phase 2 Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Subclinical Paroxysmal Nocturnal Hemoglobinuria and PNH in the Setting of Another Bone Marrow Failure Syndromes(PNH-2013) January 2013 July 2017
NCT01224483 Unknown status Multicenter Retrospective Analysis About the Clinical Characteristics of Korean Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients August 2010 December 2010
MeSH unique ID (MeSH (Medical Subject Headings))
D006457