Clinically isolated syndrome
Information
- Disease name
- Clinically isolated syndrome
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT04466150 | Active, not recruiting | Phase 4 | Impact of Ocrelizumab on Cerebrospinal Fluid Biomarkers at Multiple Sclerosis Onset | August 30, 2020 | July 2027 |
| NCT04009005 | Active, not recruiting | N/A | Clinically Isolated Syndrome and Relapsing-Remitting Multiple Sclerosis | May 1, 2020 | September 1, 2027 |
| NCT04998851 | Active, not recruiting | Phase 4 | A Study Evaluating B Cell Levels In Infants Of Lactating Women With CIS Or MS Receiving Ocrelizumab | September 16, 2021 | February 26, 2025 |
| NCT04998812 | Active, not recruiting | Phase 4 | A Study Evaluating B Cell Levels In Infants Potentially Exposed To Ocrelizumab During Pregnancy | April 13, 2022 | April 21, 2025 |
| NCT01728922 | Completed | Phase 1/Phase 2 | Dose-related Effects of Vitamin D3 on Immune Responses in Patients With Clinically Isolated Syndrome | November 6, 2012 | June 5, 2016 |
| NCT01737372 | Completed | A Pilot Study to Assess microRNA Biomarkers in Early and Later Stage Multiple Sclerosis | November 2012 | October 2016 | |
| NCT02043964 | Completed | N/A | Tear Analysis by Isoelectric Focusing in Clinically Isolated Syndrome as Multiple Sclerosis Criterion | October 2012 | December 2018 |
| NCT02254304 | Completed | Phase 4 | Effectiveness of Rebif® in Clinically Isolated Syndrome and Relapsing Multiple Sclerosis Using RebiSmart™ | December 31, 2014 | August 20, 2016 |
| NCT02549703 | Completed | Mitochondrial Dysfunction and Disease Progression | September 2015 | September 27, 2018 | |
| NCT02671682 | Completed | N/A | Immunoadsorption vs. Plasmapheresis in the Escalation Therapy of Relapse in Multiple Sclerosis | February 26, 2016 | January 25, 2019 |
| NCT00232193 | Completed | Safety/Effectiveness of Adding Monthly Dexamethasone to Weekly Avonex for MS | December 2003 | August 2010 | |
| NCT00287079 | Completed | Phase 3 | A Prospective Study Looking at the Use of Rebif® in Subjects With Clinically Isolated Syndrome | October 2005 | November 2008 |
| NCT00617383 | Completed | AT RISK FOR MS - Clinical Conversion of Female Monozygotic Twins Discordant for CIS/MS | February 2008 | December 2010 | |
| NCT00813709 | Completed | Phase 3 | Long-term Follow-Up of Patients Who Participated in Study 27025 (REFLEX) | December 2008 | September 2013 |
| NCT03438357 | Completed | Evaluation of an Automatic Segmentation Software (Pixyl.Neuro) to Track Lesions in Multiple Sclerosis Patients Via Cerebral MRI | January 2, 2019 | July 6, 2022 | |
| NCT03451955 | Completed | N/A | The Effect of a Gluten Free Diet on the Permeability of the Blood Brain Barrier in Patients With CIS | January 19, 2018 | June 16, 2022 |
| NCT03872583 | Completed | N/A | Understanding Magnetic Resonance Imaging in Multiple Sclerosis | March 15, 2019 | December 1, 2022 |
| NCT04387110 | Completed | Ocrelizumab in Breastmilk | August 7, 2020 | March 1, 2022 | |
| NCT04705610 | Completed | N/A | Social Cognition in Multiple Sclerosis, From a Study of Eye Movement and Gaze Strategies Using Video-oculography | May 23, 2017 | June 26, 2019 |
| NCT06395909 | Completed | A Study to Assess the Effectiveness and Safety of Mayzent in Chinese Patients With Relapsing Forms of Multiple Sclerosis | April 23, 2023 | August 31, 2023 | |
| NCT05706220 | Enrolling by invitation | Visual Processing Speed and Objective Analysis of Ocular Movements in Multiple Sclerosis | June 13, 2022 | December 31, 2023 | |
| NCT06455332 | Not yet recruiting | N/A | Predictive Value of the Optic Nerve Involvement in Clinically Isolated Syndrome | July 1, 2024 | July 1, 2028 |
| NCT06280755 | Not yet recruiting | Clinical Impact Through AI-assisted MS Care - A Retrospective Multi-center Observational Study. | March 2024 | April 2027 | |
| NCT06274671 | Not yet recruiting | Glymphatic MRI in Clinically Isolated Syndrome | March 1, 2024 | May 15, 2025 | |
| NCT05057676 | Recruiting | N/A | Autoimmune Intervention Mastery Course Study | December 1, 2021 | December 1, 2026 |
| NCT03979391 | Recruiting | N/A | Isoelectric Focusing of Tears in Children With Radiologically Isolated or Clinically Isolated Syndrome | September 26, 2019 | November 26, 2024 |
| NCT04798651 | Recruiting | N/A | Pathogenicity of B and CD4 T Cell Subsets in Multiple Sclerosis | September 30, 2021 | September 2026 |
| NCT03586986 | Recruiting | Risk Factors in Early Multiple Sclerosis | July 26, 2018 | May 2024 | |
| NCT05154370 | Recruiting | China National Registry of Neuro-Inflammatory Diseases | December 15, 2021 | November 1, 2026 | |
| NCT05204459 | Recruiting | MS-ResearchBiomarkerS | November 11, 2021 | November 11, 2041 | |
| NCT05277740 | Recruiting | Implementation of a Novel Functional Eye-Tracking Biomarker for Multiple Sclerosis | September 1, 2022 | July 2024 | |
| NCT00595920 | Terminated | Phase 2 | Open Label Extension of Prior TERMS Study to Treat Relapsing Forms of Multiple Sclerosis | November 2007 | December 2008 |
| NCT04291456 | Terminated | Phase 3 | Minocycline in MS: Confirmation of Benefit | January 31, 2020 | December 31, 2022 |
| NCT01039103 | Terminated | Phase 2 | Nanocort in Acute Exacerbation of Relapsing-Remitting Multiple Sclerosis (MS) | December 2009 | November 2011 |
| NCT04599023 | Terminated | Assessing the Feasibility of the MSPT Device in Routine Clinical Practice in the Swiss Healthcare System | October 16, 2020 | August 31, 2022 | |
| NCT00819897 | Terminated | Longitudinal Study in Clinically Isolated Syndrome (CIS) Patients Treated With Interferon Beta | June 2008 | June 2014 | |
| NCT03004079 | Unknown status | Clinical Importance of Glucose Regulation in Relapsing MS | October 2016 | September 2020 | |
| NCT03541226 | Unknown status | Clinical Monitoring, MRI and Neuro-Ophthalmology of a Cohort of Patients With a Clinically Isolated Syndrome (CIS) | September 2014 | September 2021 | |
| NCT01371071 | Unknown status | Cohort Study of Clinically Isolated Syndrome and Early Multiple Sclerosis | January 2011 | December 2017 | |
| NCT03610139 | Unknown status | N/A | Longitudinal Effect of Vitamin D3 Replacement on Cognitive Performance and MRI Markers in Multiple Sclerosis Patients | May 21, 2018 | December 31, 2022 |