Mast cell leukemia

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Information
Disease name
Mast cell leukemia
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03580655 Active, not recruiting Phase 2 (PATHFINDER) Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285), A Selective KIT Mutation-targeted Tyrosine Kinase Inhibitor, in Patients With Advanced Systemic Mastocytosis November 21, 2018 January 31, 2026
NCT05219266 Available Managed Access Programs for PKC412, Midostaurin
NCT00112593 Completed N/A Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer November 1999
NCT00118352 Completed Phase 2 Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer March 2005 May 26, 2015
NCT00890747 Completed Phase 1 Sunitinib Malate in Treating HIV-Positive Patients With Cancer Receiving Antiretroviral Therapy August 2009
NCT00898079 Completed Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer October 13, 2003 June 30, 2018
NCT01053494 Completed N/A Massage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Cancer April 2010 February 2012
NCT01199562 Completed Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant December 2010 December 2013
NCT00006251 Completed Phase 1/Phase 2 Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine, Mycophenolate Mofetil, Donor Lymphocyte Infusion in Treating Patients With Hematopoietic Cancer May 2000
NCT01273766 Completed Phase 2 Deferasirox in Treating Iron Overload Caused By Blood Transfusions in Patients With Hematologic Malignancies January 2011 December 2014
NCT01807598 Completed Phase 2 Brentuximab Vedotin in Treating Patients With Advanced Systemic Mastocytosis or Mast Cell Leukemia September 2013 September 2017
NCT01869777 Completed N/A Bioelectrical Impedance Measurement for Predicting Treatment Outcome in Patients With Newly Diagnosed Acute Leukemia July 2013 May 2020
NCT02561988 Completed Phase 1 (EXPLORER) Study of BLU-285 in Patients With Advanced Systemic Mastocytosis (AdvSM) and Relapsed or Refractory Myeloid Malignancies March 10, 2016 January 19, 2023
NCT01231919 Completed Phase 1 MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia January 2011
NCT00014235 Completed N/A Fludarabine Phosphate and Total-Body Radiation Followed by Donor Peripheral Blood Stem Cell Transplant and Immunosuppression in Treating Patients With Hematologic Malignancies December 2000
NCT04695431 Completed Retrospective Study Assessing the Effect of Avapritinib Versus Best Available Therapy in Patients With AdvSM December 2, 2020 October 4, 2021
NCT02415608 Terminated Phase 2 Ibrutinib in Treating Patients With Advanced Systemic Mastocytosis March 2015 June 14, 2017
NCT00387426 Terminated Phase 2 Sunitinib in Treating Patients With Idiopathic Myelofibrosis September 2006 February 2009
NCT03214666 Terminated Phase 1/Phase 2 GTB-3550 Tri-Specific Killer Engager (TriKE®) for High Risk Hematological Malignancies January 1, 2020 September 29, 2021
OrphaNumber from OrphaNet (Orphanet)
98851