Ascites

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Information
Disease name
Ascites
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04315571 Active, not recruiting N/A Comparing Ascites Relief In Two Standard Treatments: Large Volume Paracentesis Vs. Early Tips Using Viatorr Controlled Expansion Stents March 24, 2020 January 1, 2026
NCT03973866 Active, not recruiting N/A Alfapump® System in the Treatment of Refractory or Recurrent Ascites (POSEIDON Study) September 16, 2019 June 30, 2024
NCT00108355 Completed Phase 4 Vasoconstrictors as Alternatives to Albumin After Large-Volume Paracentesis (LVP) in Cirrhosis December 2003 August 2012
NCT00115947 Completed Phase 2/Phase 3 Renal and Cardiovascular Effects of Terlipressin in Patients With Cirrhosis and Ascites December 2004 January 2006
NCT00327444 Completed Phase 2/Phase 3 Study of the Effect of Intravenous AVE0005 (VEGF Trap) in Advanced Ovarian Cancer Patients With Recurrent Symptomatic Malignant Ascites July 2006 October 2009
NCT00358878 Completed Phase 3 Cirrhotic Ascites Treatment With Satavaptan in Patients With Ascites Due to Cirrhosis of the Liver (CATS) July 2006 December 2008
NCT01030185 Completed Phase 2/Phase 3 Safety and Performance of the Automated Fluid Shunt in Patients With Ascites and Diuretic Resistance February 2010 June 2013
NCT00006166 Completed Phase 3 North American Study for the Treatment of Refractory Ascites (NASTRA) March 1997 October 2001
NCT00490217 Completed Spontaneous Bacterial Peritonitis: Incidence, Risk Factors and Outcome December 1993 March 2007
NCT00501384 Completed Phase 2 Satavaptan Dose-Ranging Study in the Prevention of Ascites April 2004 May 2005
NCT00501566 Completed Phase 2 Satavaptan Dose-Ranging Study in Normonatraemic Patients With Cirrhotic Ascites April 2004 January 2005
NCT00501722 Completed Phase 2 Satavaptan Dose-Ranging Study in Hyponatraemic Patients With Cirrhotic Ascites April 2004 March 2005
NCT00570622 Completed Phase 4 Effect of Pioglitazone on Portal and Systemic Hemodynamics in Patients With Advanced Cirrhosis December 2004 November 2008
NCT00591968 Completed N/A Telesonography Adaptation and Use to Improve the Standard of Patient Care Within a Dominican Community January 2008 March 2008
NCT00741663 Completed Phase 4 Spironolactone Versus Spironolactone Plus Furosemide (SVSSF) April 2005 September 2008
NCT00825877 Completed Long-term Follow-up of HALT-C Sustained Virological Responders January 15, 2009 June 29, 2012
NCT00907673 Completed N/A The Automated Fluid Shunt (AFS)in Chronic Congestive Heart Failure May 2009 March 2010
NCT00968695 Completed Phase 4 Effects of Long Term Albumin 20% Administration in Patients With Cirrhosis and Ascites. July 2009 April 2014
NCT00005906 Completed Phase 2 Treatment With Octreotide in Patients With Lymphangioleiomyomatosis June 2000
NCT01059396 Completed Phase 4 Study on B-blockers to Prevent Decompensation of Cirrhosis With HTPortal January 28, 2010 July 15, 2015
NCT01150916 Completed N/A B-type Natriuretic Peptide in the Diagnosis of Heart Failure Related Ascites June 2010 March 2012
NCT01188746 Completed N/A Impact of Palliative Catheter Placement on the Quality of Life of Patients With Refractory Ascites August 2010 February 2020
NCT01288794 Completed Phase 4 Human Albumin for the Treatment of Ascites in Patients With Hepatic Cirrhosis March 2011 May 2016
NCT01292304 Completed Phase 4 Tolvaptan for Ascites in Cirrhotic Patients March 2012 January 2015
NCT01349335 Completed Phase 2 Dose Exploring and Setting Study for Tolvaptan to Treat Hepatic Cirrhosis With Ascites April 2009 April 2010
NCT01349348 Completed Phase 3 Phase III Study of Tolvaptan Tablet to Treat Cirrhosis Ascites October 2010 July 2012
NCT01359462 Completed Phase 1 Multiple-dose Pharmacokinetics Study of Tolvaptan Tablets in Chinese Patients With Hepatocirrhosis April 2009 January 2010
NCT01403987 Completed N/A Improving Performance of Paracentesis in Medical Residency Training January 2011 March 2012
NCT01578226 Completed Procalcitonin in Cirrhotic Patients at High Risk for Sepsis October 2009 September 2011
NCT01769040 Completed Phase 4 Intestinal Decontamination With Rifaximin. The Inflammatory and Circulatory State in Patients With Cirrhosis November 2012 January 2016
NCT02400164 Completed N/A A (M)Ulti-center, Prospective, (O)Pen Label, Uncontrolled Feasibility (S)Tudy to Assess the Safety and Effectiveness of an Automatic Low Flow (A)Scites (Alfa) Pump (I)n Patients With (C)Irrhosis and Refractory or Recurrent Ascites March 2015 March 31, 2018
NCT02608658 Completed N/A Evaluation of Serum-Derived Bovine Immunoglobulin Protein Isolate in Subjects With Decompensated Cirrhosis With Ascites March 2016 April 27, 2017
NCT02638051 Completed Phase 2 Local mEHT + TCM Versus Intraperitoneal Chemoinfusion in Treatment of Malignant Ascites: Phase II RCT January 2014 December 2015
NCT02649335 Completed Phase 3 To Study the Effect of Nonselective Beta Blockers in Advanced Stage Liver Disease With Ascites July 1, 2015 December 30, 2016
NCT02787772 Completed N/A Abdominal Hernia in Cirrhotic Patients: Surgery or Conservative Treatment? January 2009 January 2016
NCT02821377 Completed Phase 2 Metabolic Effects of Furosemide +HSS in Refractory Ascites December 2013 April 2016
NCT02975726 Completed N/A Peritoneal Dialysis Catheters for the Treatment of Refractory Ascites January 2017 February 2019
NCT03069131 Completed Phase 3 Two Strategies of Primary Prophylaxis of Spontaneous Bacterial Peritonitis in Severe Cirrhotic Patients With Ascites March 20, 2018 March 20, 2023
NCT03263598 Completed Validation of Diagnostic Usefulness of the Random Urine Na/K Ratio for Replacement of 24hr Urine Na Excretion in Cirrhotic Patients With Ascites May 2016 February 2020
NCT03327688 Completed N/A Point-of-care Ultrasound in Finland October 20, 2017 December 31, 2019
NCT03493204 Completed N/A Tackling 30-day Readmissions in Patients With Cirrhosis: The SALTYFOOD Trial April 24, 2018 August 19, 2019
NCT04245553 Completed N/A Does Point of Care Ultrasound Change Needle Insertion Location During Routine Bedside Paracentesis? February 7, 2020 March 1, 2021
NCT04533854 Completed Investigating Signal Change in Malignant and Non-malignant Pleural Effusions and asCitic Fluid Using fTiR Analysis March 26, 2021 September 26, 2023
NCT04641364 Completed Phase 1 Safety and Tolerance Study of Recombinant Human Albumin Injection in Healthy Subjects. June 24, 2019 May 6, 2020
NCT04650295 Completed N/A Non-Pharmaceutical Intervention for Cirrhotic Cramps Reduction: The NICCles Trial January 18, 2021 December 2, 2021
NCT04675775 Completed N/A The BRAINFOOD Trial to Prevent Recurrent Hepatic Encephalopathy. January 21, 2021 March 5, 2023
NCT04701697 Completed Phase 1 Phase Ib of Recombinant Human Albumin Injection March 15, 2020 October 25, 2020
NCT05013502 Completed Phase 1 Empagliflozin in Diuretic Refractory Ascites November 15, 2021 June 30, 2023
NCT05309200 Completed Phase 2 A Study of OCE-205 in Participants With Cirrhosis With Ascites Who Developed Hepatorenal Syndrome-Acute Kidney Injury April 28, 2022 October 13, 2023
NCT05278013 Enrolling by invitation N/A Utility of 2- Octyl Cyanoacrylate (2-OCA) January 13, 2022 January 13, 2024
NCT05569798 Not yet recruiting N/A The INSIGHT Feasibility Study Ultrasound in the Intensive Care Unit: A Randomised Controlled Feasibility Trial December 4, 2023 December 1, 2024
NCT06436807 Not yet recruiting PMCF Study of the CE-marked Drainova® ArgentiC Catheter May 2024 August 2026
NCT05867602 Recruiting Phase 2 High Dose Albumin in Refractory Ascites March 25, 2019 March 2026
NCT03506893 Recruiting N/A Medical-economic Evaluation of the Care of Refractory Ascites by Implantation of Alfapump® Device in Cirrhotic Patients July 17, 2018 December 31, 2025
NCT04767945 Recruiting Cirrhosis Registry of Hospitalized Patients July 1, 2014 December 31, 2029
NCT05900050 Recruiting Phase 2 Efficacy, Safety and Tolerability of VS-01 in Adult Patients With Acute-on-Chronic Liver Failure and Ascites (UNVEIL-IT)™ July 2, 2023 June 2025
NCT05511766 Recruiting Phase 2/Phase 3 Allopurinol Versus Atorvastatin to Prevent Complications of Liver Cirrhosis November 15, 2022 January 30, 2025
NCT05734729 Recruiting N/A Clinical Validation of Programmable Drain Fluid Regulator to Reduce Morbidity, Care Requirements, and Improve Outcomes February 27, 2023 September 2025
NCT05025878 Recruiting 13C-Glucose Tracing of Tumour and T Cells in the Ascites of Ovarian Cancer Patients. October 20, 2021 August 2023
NCT03267615 Recruiting VICIS - Vienna Cirrhosis Study February 1, 2017 December 31, 2027
NCT05700708 Recruiting Point-of-Care Echocardiography to Assess Impact of Dynamic Cardiac Function, Renal and Cardiac Biomarkers in Cirrhosis With Refractory Ascites November 15, 2022 July 15, 2024
NCT02742428 Suspended N/A Preoperative Ascites Drainage Versus Standard Care for Patients With Advanced Ovarian Cancer January 2018 March 2020
NCT00511394 Suspended N/A Acute Hemodynamics of Albumin Versus Normal Saline in Cirrhosis May 2007 December 2008
NCT01701297 Terminated Phase 2 VSL#3 and Spontaneous Bacterial Peritonitis February 2012 October 2014
NCT00796861 Terminated Phase 2 Trial of Sunitinib for Refractory Malignant Ascites May 2007 April 2011
NCT00366795 Terminated Phase 3 Satavaptan for the Prevention of Ascites Recurrence in Patients With Ascites Due to Cirrhosis of the Liver August 2006 December 2008
NCT01455246 Terminated Phase 2/Phase 3 Daptomycin + Meropenem Versus Ceftazidime in the Treatment of Nosocomial Spontaneous Bacterial Peritonitis October 2010 July 2014
NCT03827200 Terminated Phase 2 A Study Evaluating the Utility of Ambrisentan in Lowering Portal Pressure in Patients With Liver Cirrhosis April 11, 2019 January 21, 2021
NCT00359437 Terminated Phase 3 Satavaptan in the Prevention of Ascites Recurrence in Patients With Ascites Due to Cirrhosis of the Liver July 2006 October 2008
NCT01236339 Terminated N/A Early TIPS for Ascites Study December 2010 March 2013
NCT04112199 Terminated Phase 2 A Study for Evaluation of BIV201 to Reduce Ascites and Complications in Patients With Cirrhosis and Refractory Ascites June 17, 2021 May 8, 2023
NCT04232384 Terminated N/A Comparison of "Roll-over' Technique With Standard Abdominal Paracentesis in Suspected Peritoneal Carcinomatosis June 15, 2020 July 1, 2021
NCT02417753 Terminated Phase 2 AZD9150, a STAT3 Antisense Oligonucleotide, in People With Malignant Ascites April 3, 2015 April 7, 2016
NCT00548366 Terminated Phase 4 Sodium Restriction in the Management of Cirrhotic Ascites October 2007 September 2010
NCT04550091 Unknown status Role Of Multi-detector Computed Tomography In Differentiation Between Different Types Of Ascites October 19, 2020 October 2022
NCT04640116 Unknown status N/A TIPS Combined With Microwave Ablation in HCC Patients With Refractory Ascites February 1, 2021 June 30, 2023
NCT02755701 Unknown status Phase 4 The Effect of Branched-chain Amino Acid on the Improvement of Serum Albumin Level in Cirrhotic Patients With Ascites July 2016 December 2018
NCT02811406 Unknown status N/A The Role of Intravenous Albumin Replacement During Abdominal Paracentesis in Patients With Malignancy Related Ascites June 2016 December 2017
NCT02891642 Unknown status Liquid Biopsy With Immunomagnetic Beads Capture Technique for Malignant Cell Detection in Body Fluid September 2016 February 2021
NCT03205748 Unknown status Evaluation of Different Etiologies of Obscure Ascites August 1, 2017 November 2018
NCT03210298 Unknown status International Registry of Patients Treated With Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) January 2016 September 2022
NCT05220891 Unknown status Comparison of Crystalloid and Colloid I.V Fluid Therapy in Prevention of Paracentesis Induced Circulatory Dysfunction (PICD) and Renal Dysfunction in Patients With Decompensated Liver Cirrhosis in Egypt: a Randomized Piolet Study January 11, 2023 February 11, 2024
NCT03341221 Unknown status Diagnosis of Ascites in Infants and Children December 1, 2017 November 1, 2018
NCT01073345 Unknown status Portal Venous Hemodynamic Changes After Hepatectomy February 2010 December 2010
NCT04279327 Unknown status Cell Block Immunohistochemistry in Effusion Cytology April 1, 2020 January 2022
NCT01421550 Unknown status Phase 3 Conservative Treatment Versus Elective Repair of Umbilical Hernia in Patients With Ascites and Liver Cirrhosis January 2011 December 2015
NCT00239096 Unknown status Phase 4 Prevention of Decompensation in Liver Cirrhosis September 2005 September 2011
NCT01716611 Unknown status Phase 4 Tolvaptan for Hyponatremia in Cirrhotic Patients With Ascites November 2012 February 2014
NCT02022150 Unknown status Body Composition Analysis in Cirrhotic Undergoing Paracentesis December 2012 December 2021
NCT02120196 Unknown status Phase 3 Comparative Study of Rifaximin Versus Norfloxacin in the Secondary Prophylaxis of Spontaneous Bacterial Peritonitis January 2014 December 2023
NCT02895919 Withdrawn Bedside Inoculation of Ascitic Fluid in Diagnostic Paracentesis August 22, 2016 August 19, 2018
NCT01331785 Withdrawn N/A Mechanism and the Effect of Midodrine on Portal Pressures in Patients With Cirrhosis April 2011 July 2012
NCT00603200 Withdrawn Effect of Large Volume Paracentesis on Fatigue in Cirrhosis January 2008 December 2009
NCT01777971 Withdrawn The Effect of a Large-volume Paracentesis on Fatigue, Sleep, and Quality of Life in Cirrhosis July 2012 October 2014
NCT01091233 Withdrawn The Influence of Paracentesis on Intra-abdominal Pressure and Kidney Function in Critically Ill Patients With Liver Cirrhosis and Ascites: an Observational Study March 2010 December 2012
NCT01801228 Withdrawn Phase 2 Eplerenone Versus Spironolactone as Treatment of Ascites Due to Liver Cirrhosis; a Study of Efficacy and Side Effects February 2013 October 2015
NCT00760032 Withdrawn Phase 4 Lipopolysaccharide Binding Protein and Development of Infectious Events in Cirrhotic Patients
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0001541
ICD10 preferred id (Insert disease from ICD10)
D0014993
ICD10 class code (Insert disease from ICD10)
R18
MeSH unique ID (MeSH (Medical Subject Headings))
D001201