Opioid-Related Disorders
Information
- Disease name
- Opioid-Related Disorders
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05577026 | Active, not recruiting | N/A | Safe Prescription of Opioids in Primary Care | February 9, 2023 | January 2027 |
| NCT03950492 | Active, not recruiting | N/A | Feasibility of Deep Brain Stimulation as a Novel Treatment for Refractory Opioid Use Disorder | September 30, 2019 | December 2023 |
| NCT05122676 | Active, not recruiting | N/A | More Individualized Care: Assessment and Recovery Through Engagement | November 10, 2021 | August 2024 |
| NCT05859035 | Active, not recruiting | N/A | Informational App Development for mHealth for Patient Self-Management of Opioid Use Disorder | June 29, 2023 | January 10, 2024 |
| NCT05657106 | Active, not recruiting | N/A | Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk | March 6, 2023 | July 31, 2027 |
| NCT03949764 | Active, not recruiting | Phase 4 | The Kentucky Viral Hepatitis Treatment Study | September 23, 2019 | December 31, 2024 |
| NCT03918850 | Active, not recruiting | Phase 3 | Medication Treatment for Opioid Use Disorder in Expectant Mothers | July 21, 2020 | January 31, 2025 |
| NCT03911466 | Active, not recruiting | Phase 3 | Medication Treatment for Opioid Use Disorder in Expectant Mothers: Conceptual Model Assessments Sub-study | July 21, 2020 | January 31, 2025 |
| NCT03698669 | Active, not recruiting | N/A | Treating Chronic Pain in Buprenorphine Patients in Primary Care Settings | August 21, 2019 | November 2024 |
| NCT02751762 | Active, not recruiting | A Prospective Investigation of the Risks of Opioid Misuse, Abuse, and Addiction Among Patients Treated With Opioids for the Treatment of Chronic Pain | November 1, 2017 | March 2023 | |
| NCT00000219 | Completed | Phase 1 | Buprenorphine Dose Alteration Study - 1 | December 1991 | July 2001 |
| NCT00000220 | Completed | Phase 1 | Gradual Vs. Rapid Buprenorphine Detoxification - 2 | June 1991 | July 2001 |
| NCT00000221 | Completed | Phase 1 | Alternate-Day Buprenorphine Administration. Phase I - 3 | April 1992 | |
| NCT00000222 | Completed | Phase 1 | Alternate-Day Buprenorphine Administration. Phase II - 4 | July 1992 | |
| NCT00000223 | Completed | Phase 2 | Alternate-Day Buprenorphine Administration. Phase IV - 5 | June 1993 | |
| NCT00000224 | Completed | Phase 1 | Alternate-Day Buprenorphine. Phase V - 6 | February 1993 | |
| NCT00000225 | Completed | Phase 2 | Alternate-Day Buprenorphine Administration. Phase VI - 7 | December 1992 | |
| NCT00000226 | Completed | Phase 2 | Alternate-Day Buprenorphine Administration. Phase VII - 8 | November 1994 | |
| NCT00000227 | Completed | Phase 2 | Alternate-Day Buprenorphine Administration. Phase VIII - 9 | August 1994 | |
| NCT00000228 | Completed | Phase 2 | Buprenorphine Detox With Two Types of Treatment. BBD I - 10 | August 1994 | |
| NCT00000229 | Completed | Phase 2 | Buprenorphine Detox With Two Types of Treatment. BBD II - 11 | October 1995 | |
| NCT00000230 | Completed | Phase 2 | Buprenorphine Detoxification With Two Types of Treatment. BBD III - 12 | January 1995 | |
| NCT00000231 | Completed | Phase 2 | Buprenorphine Detoxification With Two Types of Treatment. BBD IV - 13 | February 1992 | |
| NCT00000232 | Completed | Phase 2 | Alternate Day Buprenorphine Administration, Phase IX - 14 | March 1992 | |
| NCT00000233 | Completed | Phase 2 | Alternate Day Buprenorphine Administration, Phase X - 15 | May 1993 | |
| NCT00000234 | Completed | Phase 2 | Alternate Day Buprenorphine Administration, Phase XI - 16 | ||
| NCT00000235 | Completed | Phase 2 | Alternate Day Buprenorphine Administration, Phase XII - 17 | ||
| NCT00000236 | Completed | Phase 2 | Buprenorphine Pharmacology Related to Addiction Treatment - 18 | ||
| NCT00000237 | Completed | Phase 2 | Buprenorphine Detoxification - BBDVI - 19 | May 1997 | |
| NCT00000238 | Completed | Phase 2 | Temporal Discounting Delayed Outcomes on Opioid-Dependent Outpatients - 20 | August 1997 | |
| NCT00000239 | Completed | Phase 2 | Buprenorphine Pharmacology Related to Addiction Treatment - 21 | ||
| NCT00000240 | Completed | Phase 2 | Combined Buprenorphine and Behavioral Treatment With and Without Contingent Reinforcement on Opioid and Cocaine Abstinence. - 22 | April 1999 | |
| NCT00000244 | Completed | Phase 2 | Effects of Dynorphin 1-13 on Heroin Addiction - 1 | August 1994 | March 1997 |
| NCT00000249 | Completed | Phase 2 | Effects of Subanesthetic Concentrations of Nitrous Oxide - 1 | September 1993 | June 1995 |
| NCT00000250 | Completed | Phase 2 | Cold Water Immersion Modulates Reinforcing Effects of Nitrous Oxide - 2 | December 1993 | May 1995 |
| NCT00000251 | Completed | Phase 2 | Effects of Subanesthetic Concentrations of Isoflurane/Nitrous Oxide - 3 | April 1994 | January 1996 |
| NCT00000252 | Completed | Phase 2 | Lack of Acute Tolerance Development to Effects of Nitrous Oxide - 4 | June 1994 | June 1996 |
| NCT00000253 | Completed | N/A | Effects of Nitrous Oxide: A Dose-Response Analysis - 5 | November 1994 | March 1996 |
| NCT00000254 | Completed | Phase 2 | Isoflurane at Subanesthetic Concentrations - 6 | January 1995 | September 1995 |
| NCT00000255 | Completed | Phase 2 | Differential Acute Tolerance Development to Effects of Nitrous Oxide - 7 | April 1995 | May 1996 |
| NCT00000256 | Completed | N/A | Reinforcing Effects of Brief Exposures to Nitrous Oxide - 8 | August 1995 | November 1996 |
| NCT00000257 | Completed | N/A | Effects of Alcohol History on Effects of Nitrous Oxide - 9 | September 1995 | April 1997 |
| NCT00000258 | Completed | N/A | Role of Instructions in Nitrous Oxide Effects and Choice - 10 | April 1996 | November 1997 |
| NCT00000259 | Completed | N/A | Sevoflurane vs Nitrous Oxide Inhalation at Subanesthetic Concentrations - 11 | August 1996 | November 1997 |
| NCT00000260 | Completed | N/A | Effects of Behavioral Contingencies on Effects of Nitrous Oxide - 12 | June 1997 | January 1998 |
| NCT00000261 | Completed | Phase 2 | Effects of Alcohol History on Effects of Sevoflurane and Nitrous Oxide - 13 | November 1997 | October 1998 |
| NCT00000262 | Completed | N/A | Effects of Combined Sevoflurane and Nitrous Oxide Inhalation - 14 | November 1996 | February 1999 |
| NCT00000263 | Completed | N/A | Effects of Combined Alcohol and Nitrous Oxide Intake - 15 | January 1997 | October 1998 |
| NCT00000264 | Completed | N/A | Subjective/Psychomotor/ Effects of Combined Alcohol & Nitrous Oxide - 16 | September 1997 | October 1999 |
| NCT00000265 | Completed | Subjective Effects of Nitrous Oxide in Dental Patients - 17 | July 1997 | January 2002 | |
| NCT00000273 | Completed | Phase 2 | A Laboratory Model for Heroin Abuse Medications - 8 | August 1995 | November 2005 |
| NCT00000279 | Completed | Phase 2 | Novel Medications for Opiate Detoxification - 4 | September 1994 | August 1999 |
| NCT00000298 | Completed | Phase 2 | Buprenorphine Combination Tablet Feasibility - 1 | August 1995 | |
| NCT00000299 | Completed | Phase 2 | Rapid Opiate Detoxification and Naltrexone Induction Using Buprenorphine - 2 | October 2008 | November 2009 |
| NCT00000300 | Completed | Phase 4 | Feasibility Study of Take-Home LAAM Medication - 3 | March 1995 | |
| NCT00000306 | Completed | Phase 2 | Dextroamphetamine as Adjunct in Cocaine/Opiate Dependent Patients - 3 | September 1994 | September 2001 |
| NCT00000311 | Completed | Phase 3 | Combining Behavioral Treatment With Agonist Maintenance - 1 | February 1995 | February 1999 |
| NCT00000318 | Completed | Phase 2 | Buprenorphine Maintenance Dose Schedule and Treatment Setting - 1 | December 1994 | August 2007 |
| NCT00000319 | Completed | Phase 2 | Buprenorphine Maintenance Dose Schedule and Treatment Setting - 2 | June 1996 | January 2005 |
| NCT00000320 | Completed | Phase 1/Phase 2 | Buprenorphine Formulation Comparison: Sublingual Tablet vs. Solution - 1 | October 1997 | August 1999 |
| NCT03377855 | Completed | N/A | Addressing Origins of the Opioid Epidemic by Improving Prescribing for Opioid-Naive Patients | February 1, 2018 | December 31, 2019 |
| NCT00000202 | Completed | Phase 2 | Buprenorphine Maintenance for Opioid Addicts - 1 | August 1988 | May 2006 |
| NCT00000203 | Completed | Phase 2 | Buprenorphine Maintenance for Opioid Addicts - 2 | August 1988 | May 2006 |
| NCT00000204 | Completed | Phase 2 | Buprenorphine Maintenance for Opioid Addicts - 3 | August 1988 | May 2006 |
| NCT00000205 | Completed | Phase 3 | Buprenorphine Maintenance Protocol - 1 | October 1990 | September 1993 |
| NCT00000206 | Completed | Phase 2 | Clinical Rescue Protocol - 2 | April 1991 | |
| NCT00000207 | Completed | Phase 3 | Multicenter Clinical Trial of Buprenorphine - 3 | May 1992 | |
| NCT00000208 | Completed | Phase 2 | Methadone/Buprenorphine Cross-Over Study - 4 | February 1992 | |
| NCT00000209 | Completed | Phase 2 | Buprenorphine Dosing Interval - 5 | November 1992 | |
| NCT00000216 | Completed | Phase 3 | Buprenorphine Maintenance for Cocaine Abusing Opioid Addicts - 1 | January 2005 | |
| NCT01570699 | Completed | Variation of COMT Val158Met Polymorphism Between COM-ON Patients and METHADOSE Patients | December 2012 | June 2016 | |
| NCT01595867 | Completed | Phase 1 | Abuse Potential Assessment of Intranasally Administered EMBEDA Compared To Morphine Sulfate Controlled Release And Placebo | August 2010 | January 2011 |
| NCT01733693 | Completed | Phase 4 | Neurocognitive Effects of Opiate Agonist Treatment | January 2013 | June 2017 |
| NCT01759446 | Completed | Phase 2 | Abuse Potential of Intranasal VYCAVERT Tablets (Hydrocodone Bitartrate/Acetaminophen) in Recreational Opioid Users | February 2013 | April 2013 |
| NCT01848054 | Completed | Phase 3 | Study to Assess Efficacy and Safety of BNX Sublingual Tablets for the Induction of Treatment of Opioid Dependence | June 2013 | January 2014 |
| NCT01880086 | Completed | Phase 2 | Clomiphene Citrate for the Treatment of Low Testosterone Associated With Chronic Opioid Pain Medication Administration | August 2013 | November 2017 |
| NCT01894087 | Completed | N/A | Safety & Prevention Outcomes Study | April 2013 | January 2015 |
| NCT01909076 | Completed | N/A | Transforming Opioid Prescribing in Primary Care | January 2014 | March 2016 |
| NCT01999946 | Completed | Phase 4 | Extended-Release Naltrexone Opioid Treatment at Jail Re-Entry | June 27, 2014 | December 24, 2020 |
| NCT02093559 | Completed | N/A | Repeated-dose Brief Intervention to Reduce Overdose and Risk Behaviors Among Naloxone Recipients | July 2014 | December 2016 |
| NCT02247024 | Completed | Pupil Response in Patients on Opioids. | January 2015 | November 2018 | |
| NCT02282306 | Completed | N/A | Phone Interview to Prevent Recurring Opioid Overdoses | September 2014 | February 2015 |
| NCT02360007 | Completed | Phase 1/Phase 2 | Interim Buprenorphine: Leveraging Medication + Technology to Bridge Delays in Treatment Access | January 2015 | June 2016 |
| NCT02372591 | Completed | Phase 1 | Study of the Treatment of Experimental Pain in Buprenorphine Maintained Persons With Chronic Musculoskeletal Pain | August 2015 | June 2017 |
| NCT02510014 | Completed | Phase 3 | Safety and Tolerability Study of Depot Buprenorphine in Treatment Seeking Subjects With Opioid Use Disorder | July 27, 2015 | January 31, 2017 |
| NCT02526212 | Completed | Phase 3 | Buprenorphine Group Medical Visits in Primary Care | January 1, 2017 | May 2019 |
| NCT02571400 | Completed | Prevalence and Predictors of Prolonged Post-surgical Opioid Use: a Prospective Observational Cohort Study | October 2015 | October 2016 | |
| NCT02572089 | Completed | Phase 1 | Pharmacokinetic Evaluation of Intranasal and Intramuscular Naloxone in Healthy Volunteers | October 2014 | January 2015 |
| NCT02583243 | Completed | Project BEST: Buprenorphine Entry Into Substance Abuse Treatment | May 2005 | August 2008 | |
| NCT02616523 | Completed | Phase 4 | Influence of Dexmedetomidine and Lidocaine on Opioid Consumption in Laparoscopic Intestine Resection | July 2014 | May 2016 |
| NCT02660606 | Completed | A Qualitative Study to Assess the Content Validity of the Prescription Opioid Misuse and Abuse Questionnaire | January 2, 2015 | January 18, 2016 | |
| NCT02660619 | Completed | Validation of PRISM-5-Op, Measure Of Addiction To Prescription Opioid Medication | November 17, 2015 | November 28, 2017 | |
| NCT02667158 | Completed | A Survey to Eval the Relation Between Doctor/Pharmacy Shopping and Outcomes Suggestive of Misuse, Abuse and/or Diversion | November 7, 2014 | December 19, 2018 | |
| NCT02667197 | Completed | Study to Validate Coded Medical Terms Used to Identify Opioid-Related Overdose in Databases Used for PMR Study 1B | April 7, 2015 | May 17, 2017 | |
| NCT02667210 | Completed | Study to Eval Relation Btw Doctor/Pharmacy Shopping & Outcomes of Misuse, Diversion, Abuse, Addiction by Med Rec Review | November 6, 2014 | June 21, 2017 | |
| NCT02667262 | Completed | An Observational Study to Develop Algorithms for Identifying Opioid Abuse and Addiction Based on Admin Claims Data | May 20, 2015 | May 17, 2017 | |
| NCT02668549 | Completed | Cross-Sectional Study to Define and Validate "Doctor/Pharmacy Shopping" as Outcomes Suggestive of Abuse and/or Addiction | February 5, 2015 | August 9, 2017 | |
| NCT02669901 | Completed | N/A | Naloxone Auto-injector as a Universal Precaution for Patients With Opioid Substance Use Disorder | April 4, 2016 | August 20, 2020 |
| NCT02678507 | Completed | A Quantitative Study to Assess the Construct Validity of the Prescription Opioid Misuse and Abuse Questionnaire | April 7, 2015 | June 21, 2017 | |
| NCT02750748 | Completed | Phase 1 | Pharmacokinetic Evaluation of Intranasal, Intramuscular, and Oral Naltrexone in Healthy Volunteers | July 2016 | September 2016 |
| NCT02797990 | Completed | Conflict Between Maternal Autonomy and Child Health in Substance-use | May 2016 | September 2016 | |
| NCT02896296 | Completed | Phase 3 | Open-Label Treatment Extension Study | August 17, 2016 | August 23, 2017 |
| NCT02922959 | Completed | N/A | A Tailored, Peer-delivered Intervention to Reduce Recurring Opioid Overdoses | February 7, 2017 | July 25, 2019 |
| NCT02941809 | Completed | N/A | Harnessing Placebo Effects in Methadone Treatment | December 5, 2017 | July 31, 2020 |
| NCT02969668 | Completed | Interferon-free Antiviral Treatment of Chronic Hepatitis C Virus Infection Among Opioid-substituted Patients | March 2016 | December 2019 | |
| NCT02978417 | Completed | Phase 4 | Feasibility Study of Extended-release Naltrexone (Vivitrol) in Drug Court Settings | September 21, 2017 | June 30, 2019 |
| NCT02992938 | Completed | Phase 4 | Administration of Acetazolamide to Prevent Remifentanil Induced Hyperalgesia | December 2016 | September 28, 2018 |
| NCT03022890 | Completed | N/A | Study of Yoga vs. Health Education for Chronic Pain in Persons Receiving Opioid Agonist Therapy | April 1, 2017 | July 1, 2019 |
| NCT03098407 | Completed | N/A | Opioid Dependence Treatment Therapies in Pregnancy | April 20, 2017 | October 5, 2020 |
| NCT03129347 | Completed | Phase 1 | Pharmacokinetic Evaluation of Nalmefene Administered Intranasally to Healthy Volunteers | June 1, 2017 | July 3, 2017 |
| NCT03143855 | Completed | Phase 1 | Drug Interaction and Subjective Effects of Compounds for Opioid Use Disorder | January 30, 2017 | April 5, 2019 |
| NCT03161795 | Completed | Addressing the Risks of Long-Term Opioid Therapy in Chronic Noncancer Pain | April 25, 2017 | March 12, 2018 | |
| NCT03175640 | Completed | N/A | Prescribe to Save Lives | July 12, 2017 | December 31, 2019 |
| NCT03306368 | Completed | N/A | Youth Opioid Recovery Support: A Developmentally-specific Intervention for Home Delivery of Extended Release Naltrexone | February 1, 2018 | December 1, 2019 |
| NCT03411265 | Completed | N/A | RETAIN: Retaining Opioid Users Entering Medication Assisted Treatment and Encouraging HCV/HIV Testing | November 8, 2017 | September 6, 2018 |
| NCT03521960 | Completed | Phase 1 | Buspirone for Opioid Tapering | May 30, 2018 | June 30, 2020 |
| NCT03526380 | Completed | N/A | The OPT-IN Project | October 11, 2018 | June 30, 2020 |
| NCT03567356 | Completed | N/A | Treatment of Opioid Use: Medication Adherence Therapy | May 1, 2019 | June 1, 2023 |
| NCT03604861 | Completed | An Observational Study of Environmental and SocioEconomic Factors in Opioid Recovery | August 2015 | March 2019 | |
| NCT03684681 | Completed | N/A | The Navigator Trial | November 14, 2018 | November 30, 2022 |
| NCT03779997 | Completed | N/A | Trial of Adherence App for Buprenorphine Treatment (TAAB) Study | February 15, 2019 | July 29, 2020 |
| NCT03833245 | Completed | N/A | Optimizing Pregnancy and Treatment Interventions for Moms 2.0 | March 11, 2019 | October 1, 2022 |
| NCT03838510 | Completed | N/A | Repeated-dose Behavioral Intervention to Reduce Opioid Overdose | April 22, 2019 | December 12, 2023 |
| NCT03859778 | Completed | Evaluation of Pharmacy Students' Perception of Opioid / Opiate Dependence | January 14, 2019 | March 31, 2019 | |
| NCT03891628 | Completed | N/A | Modified ABC: A Home-based Parenting Program for Opioid-dependent Mothers and Their Infants | August 13, 2018 | March 31, 2021 |
| NCT03932799 | Completed | Comparing State Payer Strategies to Prevent Unsafe Opioid Prescribing | August 6, 2019 | June 30, 2022 | |
| NCT03961789 | Completed | Assessment of the Satisfaction of Patient Undergoing Opioid Replacement Therapy Toward Their Management in Community Pharmacy | January 29, 2018 | May 21, 2019 | |
| NCT04015115 | Completed | N/A | Youth Opioid Recovery Support: Improving Care Systems | July 26, 2019 | October 31, 2020 |
| NCT04164342 | Completed | N/A | Prevalence of Chronic Pain and Its Risk Factors After a Surgical Intensive Care Unit Stay. Prospective Observational Cohort | November 27, 2019 | July 26, 2022 |
| NCT04199728 | Completed | Phase 1/Phase 2 | Use of a GLP-1R Agonist to Treat Opioid Use Disorder | October 18, 2021 | September 13, 2023 |
| NCT04235582 | Completed | N/A | Incentives to Decrease Opioid Use - Pilot | August 25, 2020 | May 15, 2021 |
| NCT04251208 | Completed | MOms in REcovery (MORE) Study: Defining Optimal Care | July 30, 2019 | January 31, 2024 | |
| NCT04272671 | Completed | N/A | De-prescribing Program to Evaluate Falls in Older Adults | February 26, 2020 | October 1, 2021 |
| NCT04314648 | Completed | N/A | Substance Use Treatment and Recovery Team (START) | December 4, 2020 | December 31, 2022 |
| NCT04320004 | Completed | N/A | Evaluation of a Medication Disposal Program in Primary Care | May 1, 2020 | June 30, 2021 |
| NCT04495673 | Completed | N/A | Combining Neuro-Imaging and Non-Invasive Brain Stimulation for Clinical Intervention in Opioid Use Disorder | January 11, 2021 | February 22, 2022 |
| NCT04675840 | Completed | N/A | Intrathecal Morphine for Robotic-assisted Laparoscopic Hysterectomy. | November 1, 2020 | June 30, 2022 |
| NCT05086796 | Completed | N/A | Substance Use Treatment and Recovery Team | November 11, 2021 | December 19, 2023 |
| NCT05803603 | Completed | N/A | Social Work Assistance and Stipends for Housing (SASH) | December 1, 2022 | January 1, 2024 |
| NCT00000334 | Completed | Phase 2 | Comparison of Buprenorphine and Methadone - 3 | December 1, 2002 | January 15, 2005 |
| NCT00000335 | Completed | Phase 2 | Activity Monitoring Assessment of Opiate Withdrawal - 4 | September 30, 1995 | May 20, 1996 |
| NCT00000341 | Completed | Phase 2 | Evaluation of Liquid vs. Tablet Buprenorphine - 6 | August 1996 | August 2000 |
| NCT00000344 | Completed | Phase 2 | Buprenorphine/Naloxone for Treatment of Opiate Dependence - 9 | August 2000 | |
| NCT00000345 | Completed | Phase 1 | Evaluation of Lofexidine for Treatment of Opiate Withdrawal - 10 | April 1996 | |
| NCT00000352 | Completed | Phase 2 | Effects of Dextromethorphan on Opioid Tolerance in Methadone Patients - 1 | December 1996 | April 1998 |
| NCT00000353 | Completed | Phase 2 | Trial of Buprenorphine/Naloxone for Opiate Dependence - 2 | October 1996 | October 1997 |
| NCT00000354 | Completed | Phase 1 | Evaluation of Lofexidine for Treatment of Opioid Withdrawal - 3 | July 1996 | December 1997 |
| NCT00000355 | Completed | Phase 1 | Effects of Buprenorphine and Naloxone in Opiate Addicts - 4 | November 1994 | March 1996 |
| NCT00000356 | Completed | Phase 2 | Evaluation of L-alpha-acetylmethadol (LAAM) in Methadone Patients - 5 | June 1991 | October 1992 |
| NCT00000357 | Completed | Phase 2 | Buprenorphine Maintenance for Opiate Dependence - 6 | June 1992 | October 1993 |
| NCT00000358 | Completed | Phase 1 | Evaluation of Lofexidine for Treatment of Opioid Withdrawal - 7 | ||
| NCT00015028 | Completed | Phase 2 | Buprenorphine/Naloxone for Opiate-Dependence Treatment - 1 | November 1996 | January 1997 |
| NCT00015041 | Completed | Phase 1 | Buprenorphine Dose Escalation Trial for Treatment of Non-Dependent Opiate Users - 2 | November 1996 | July 1998 |
| NCT00015288 | Completed | Phase 1 | Buprenorphine and Naloxone Combination Study - 10 | November 1996 | |
| NCT00018226 | Completed | Phase 2 | Effect Of Case Management Following Discharge From Methadone Treatment | April 1998 | March 2001 |
| NCT00023283 | Completed | Phase 2 | Counseling Conditions for Buprenorphine in a Primary Care Clinic - 1 | August 2000 | February 2004 |
| NCT00032942 | Completed | Phase 3 | Lofexidine for Opiate Withdrawal - 1 | April 2001 | |
| NCT00061087 | Completed | Phase 2/Phase 3 | Treatment of Adult Attention Deficit Hyperactivity Disorder (ADHD) in Methadone Patients - 1 | February 1998 | October 2004 |
| NCT00061100 | Completed | Phase 1 | HIV Counseling Intervention for Methadone-Maintained Patients - 2 | October 1999 | October 2003 |
| NCT00067184 | Completed | Fetal Neurobehavioral Development in Methadone Maintained Pregnancies | September 2002 | August 2010 | |
| NCT00078117 | Completed | Phase 3 | Suboxone: (Buprenorphine/Naloxone) Comparison of Two Taper Schedules - 1 | June 2003 | May 2005 |
| NCT00078130 | Completed | Phase 3 | Buprenorphine/Naloxone - Facilitated Rehabilitation for Opioid Dependent Adolescents - 1 | July 2003 | January 2006 |
| NCT00134888 | Completed | N/A | Blockade Efficacy of Buprenorphine/Naloxone For Opioid Dependence | December 2000 | November 2002 |
| NCT00134914 | Completed | N/A | Effects of Buprenorphine/Naloxone Administered in Different Ways For Treating Opioid Dependence | August 1996 | May 1998 |
| NCT00135759 | Completed | Phase 2 | Addition of Naltrexone to Methadone Taper | April 2005 | July 2006 |
| NCT00142779 | Completed | N/A | Fluoxetine to Reduce Cocaine Use in Cocaine and Opioid Addicts | April 2001 | March 2006 |
| NCT00142896 | Completed | Phase 2 | Tramadol to Reduce Opioid Withdrawal Symptoms | February 2005 | December 2005 |
| NCT00142909 | Completed | Phase 2 | Effectiveness of Lofexidine to Prevent Stress-Related Opiate Relapse During Naltrexone Treatment - 1 | February 2005 | January 2009 |
| NCT00142935 | Completed | N/A | Effectiveness of Opiate Replacement Therapy Administered Prior to Release From a Correctional Facility - 1 | September 2006 | December 2009 |
| NCT00149669 | Completed | N/A | Employment-based Reinforcement of Naltrexone Ingestion and Abstinence | December 2005 | December 2010 |
| NCT00158184 | Completed | Phase 2 | Prescription Opioid Effects in Abusers Versus Non-Abusers | June 2004 | June 2009 |
| NCT00158236 | Completed | N/A | Abuse Potential of Buprenorphine and Naloxone in Non-Dependent Opioid Users | January 1997 | March 1998 |
| NCT00218010 | Completed | Methadone Levels in Breast Milk of Women Taking Methadone for Opiate Addiction - 2 | November 2000 | September 2005 | |
| NCT00218101 | Completed | Phase 2 | Buprenorphine as a Treatment for Individuals Dependent on Analgesic Opioids | May 2004 | March 2005 |
| NCT00218127 | Completed | Phase 2 | Treatment of Opioid/Heroin Dependence: Comparison of Three Medication Dosing Regimens | November 2001 | July 2005 |
| NCT00218309 | Completed | Effects of Pre-Session Supplemental Hydromorphone on Drug Seeking Behavior in Opioid Dependent Individuals | September 2003 | July 2005 | |
| NCT00218361 | Completed | Effects of Post-Session Supplemental Hydromorphone on Drug Seeking Behavior in Opioid Dependent Individuals | August 2005 | ||
| NCT00218374 | Completed | N/A | Dextromethorphan, Gabapentin, and Oxycodone to Treat Opioid-Induced Hyperalgesia | October 2006 | June 2007 |
| NCT00218426 | Completed | Phase 2/Phase 3 | Addiction Treatment in Russia: Oral vs. Naltrexone Implant | July 2006 | November 4, 2010 |
| NCT00218608 | Completed | Phase 2 | Disulfiram for Treating Cocaine Dependence in Individuals Maintained on Methadone | April 2001 | January 2007 |
| NCT00237406 | Completed | Interactive Voice Response (IVR) for Methadone Patients | January 2006 | October 2006 | |
| NCT00249470 | Completed | N/A | The Therapeutic Workplace Initiation Study | April 2003 | October 2004 |
| NCT00295308 | Completed | Phase 1 | Clonidine for Relapse Prevention in Buprenorphine-Maintenance Patients | November 8, 2005 | July 30, 2014 |
| NCT00301210 | Completed | Phase 1/Phase 2 | Assessment of Tramadol as a Treatment for Opioid Addiction | January 2006 | November 2007 |
| NCT00316277 | Completed | Phase 3 | Prescription Opioid Addiction Treatment Study (POATS) | May 2006 | January 2013 |
| NCT00348868 | Completed | N/A | Buprenorphine HIV Care Integration Project | July 2006 | December 2007 |
| NCT00429767 | Completed | Sustained Release d-Amphetamine & Buprenorphine on Drug Seeking Behavior in Opioid & Cocaine Dependent Individuals | January 2007 | January 2010 | |
| NCT00460239 | Completed | Phase 2 | Buprenorphine's Dose Response Curve | January 2007 | July 2009 |
| NCT00471042 | Completed | Study of Buprenorphine Maintenance Treatment for Opioid Dependence in Primary Care | June 2006 | August 2012 | |
| NCT00473993 | Completed | Hepatitis C Among Opioid Addicts in Opioid Maintenance Treatment in Zurich, Switzerland | July 2007 | December 2007 | |
| NCT00608504 | Completed | Effects of Environmental Factors on Opiate Drug Choice in Opioid Dependent Individuals. | July 2007 | April 2009 | |
| NCT00637000 | Completed | Phase 2 | Induction of Opioid-Dependent Individuals Onto Buprenorphine and Buprenorphine/Naloxone | March 2008 | September 2008 |
| NCT00640835 | Completed | Phase 2 | Safety and Tolerability of Buprenorphine/Naloxone Film Strips | February 2008 | October 2008 |
| NCT00684554 | Completed | Phase 2/Phase 3 | Buprenorphine Maintenance Treatment of Opioid Dependence in Primary Care: A Randomized Clinical Trial | December 2007 | April 2010 |
| NCT00684840 | Completed | Effects of Stress and Other Factors on Opiate Drug Choice. | March 2008 | December 2011 | |
| NCT00698737 | Completed | Treatment Study: Reducing Cocaine/Heroin Abuse With SR-Amphetamine and Buprenorphine (ARC) | April 2008 | November 2012 | |
| NCT00710385 | Completed | Phase 3 | Abuse Liability of Suboxone Versus Subutex | September 2007 | August 2008 |
| NCT00723177 | Completed | Phase 2 | Phase IIa Study of AV411, a Glial Activation Inhibitor, for Opioid Withdrawal | October 2008 | June 2012 |
| NCT00723749 | Completed | Treatment of Opioid Dependent Patients With Suboxone: Acceptability & Safety Data From Real Life Scenario (Study P05603) | March 2008 | December 2010 | |
| NCT00725608 | Completed | Acceptability and Safety of Switching From Subutex or Other Opioid Drug Dependence Therapy to Suboxone (NIS P05444) | May 2008 | April 2011 | |
| NCT00734461 | Completed | Phase 2 | Study to Evaluate the Subjective Effects of PTI-801 in Non-Physically Dependent Subjects With a History of Drug Abuse | August 2007 | March 2009 |
| NCT00780702 | Completed | Phase 1 | Aripiprazole for Prevention of Relapse to Cocaine Use in Methadone-Maintenance Patients | May 8, 2008 | April 16, 2013 |
| NCT00992095 | Completed | N/A | Bioequivalency Study of Buprenorphine Hydrochloride 8 mg Tablet Under Fasted Conditions | August 2006 | September 2006 |
| NCT01004393 | Completed | Phase 2 | Methylnaltrexone for Opioid-induced Constipation in Cancer Patients | October 2009 | December 2013 |
| NCT01108679 | Completed | Neurocognitive Effects of Buprenorphine Among HIV+ and HIV-Opioid Users | December 1, 2009 | February 1, 2012 | |
| NCT01275599 | Completed | Phase 1 | Drug-Drug Interaction Study Between Telaprevir and Buprenorphine | January 2011 | |
| NCT01315184 | Completed | Phase 2 | Study of Computer-Based Treatment for Drug Dependence | July 2010 | July 2012 |
| NCT01344122 | Completed | N/A | Medication-Assisted Treatment Implementation in Community Correctional Environments (MATICCE) | October 2010 | September 2013 |
| NCT01471145 | Completed | Phase 4 | Depot Naltrexone Mechanism of Action in Heroin Dependent Patients Using fMRI and SPECT | January 2013 | October 2014 |
| NCT01530542 | Completed | Phase 1 | A Clinical Study To Characterize The Pharmacokinetics And The Effects Of Food On Oxycodone In Healthy Volunteers | July 2010 | September 2010 |
| NCT01536925 | Completed | Studies of Opioid Seeking Behavior: Yohimbine and Hydrocortisone Effects | December 2011 | April 2017 | |
| NCT05336188 | Enrolling by invitation | Phase 2 | Neurocognitive Mechanisms Underlying Smartphone-Assisted Prevention of Relapse in Opioid Use Disorder | May 16, 2023 | September 30, 2028 |
| NCT06084221 | Enrolling by invitation | N/A | Fatal Overdose Review Teams - Research to Enhance Surveillance Systems | September 21, 2023 | September 30, 2027 |
| NCT04499079 | Enrolling by invitation | N/A | Alliances to Disseminate Addiction Prevention and Treatment (ADAPT) | June 1, 2020 | April 30, 2025 |
| NCT06454903 | Not yet recruiting | N/A | Developing a Smartphone Application to Support Veteran Opioid Use Disorder Treatment | February 3, 2025 | May 31, 2029 |
| NCT06023459 | Not yet recruiting | Phase 3 | Extended-release Buprenorphine Compared to Sublingual Buprenorphine in Rural Settings (RXR) | July 1, 2024 | December 30, 2024 |
| NCT06387290 | Not yet recruiting | N/A | Optimizing Chronic Pain Care With Mindfulness and Chronic Pain Management Visits | May 6, 2024 | May 1, 2030 |
| NCT06134882 | Not yet recruiting | N/A | OUD Smartphone Services | April 22, 2024 | August 30, 2026 |
| NCT03804619 | Not yet recruiting | N/A | Accelerated Intermittent Theta-Burst Stimulation for Opiate Use Disorder | June 1, 2024 | December 1, 2025 |
| NCT06001749 | Not yet recruiting | Phase 2 | Psilocybin in Cancer Pain Study | July 2024 | December 31, 2026 |
| NCT05480956 | Recruiting | N/A | SIRI Checklist: An Integrated Hospital Model to Optimize HIV Prevention in Persons Who Inject Drugs | October 11, 2022 | December 2024 |
| NCT05651516 | Recruiting | Early Phase 1 | Tau PET Imaging in Opioid Use Disorder | April 25, 2023 | December 2026 |
| NCT04567784 | Recruiting | Phase 2 | Neuroimaging and CBD for Opiod Use Disorder | November 12, 2020 | November 12, 2025 |
| NCT05121428 | Recruiting | Patients' Attitudes Toward and Experiences With Buprenorphine Treatment | November 20, 2021 | March 20, 2025 | |
| NCT05141266 | Recruiting | N/A | Healthy Opioid Prescription Engagement | November 8, 2021 | December 1, 2026 |
| NCT06215963 | Recruiting | N/A | A4i-O: A Platform for Complex Behavioral Health to Address OUD | February 5, 2024 | November 2024 |
| NCT05380440 | Recruiting | N/A | Preventing Parental Opioid and/or Methamphetamine Addiction Within DHS-Involved Families: FAIR | June 9, 2021 | August 31, 2025 |
| NCT05903495 | Recruiting | N/A | Deep Brain Stimulation as a Novel Treatment for Refractory Opioid Use Disorder | July 1, 2023 | December 2028 |
| NCT03745339 | Recruiting | Outcome Inference in the Sensory Preconditioning Task in Opioid-Use Disorder | June 7, 2019 | October 1, 2024 | |
| NCT04933084 | Recruiting | N/A | Pre-operative Education Modalities to Decrease Opioid Use | September 16, 2021 | May 2024 |
| NCT05505227 | Recruiting | N/A | Developing a Tailored Stigma Reduction Intervention to Increase Buprenorphine Prescribing | September 1, 2022 | June 30, 2025 |
| NCT04325659 | Recruiting | Phase 2/Phase 3 | An Innovative Intervention for OUD Treatment | November 15, 2020 | October 30, 2025 |
| NCT05512897 | Recruiting | N/A | Does ESP Block Reduce Pain and Opiates Consumption After Surgery | September 1, 2020 | February 2024 |
| NCT05840276 | Recruiting | N/A | Cryoneurolysis Prior to Total Knee Arthroplasty | August 30, 2023 | December 1, 2024 |
| NCT03911739 | Recruiting | Phase 3 | Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-study | June 14, 2021 | January 31, 2025 |
| NCT05603702 | Recruiting | Phase 1 | STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis | March 17, 2023 | December 31, 2024 |
| NCT00396734 | Suspended | N/A | The Effects of Pharmacotherapy on Brain Mechanisms Underlying Cocaine Dependence. | April 2007 | April 2011 |
| NCT03925610 | Terminated | Recovery of Ventilation After General Anesthesia in Morbidly Obese Patients | April 10, 2019 | March 30, 2020 | |
| NCT00149539 | Terminated | Phase 2 | Abuse Potential of Buprenorphine/Naloxone | June 2004 | January 2006 |
| NCT01517165 | Terminated | Phase 1 | Pioglitazone to Treat Opioid Withdrawal Symptoms | January 4, 2012 | February 2, 2015 |
| NCT03316339 | Terminated | Phase 3 | Postoperative and Opioid Free Anesthesia | November 29, 2017 | June 19, 2019 |
| NCT03427424 | Terminated | Imaging Biomarker for Addiction Treatment Outcome | July 10, 2019 | April 29, 2024 | |
| NCT04188288 | Terminated | N/A | Neurofeedback in Individuals With Substance Use Disorders | July 1, 2021 | March 15, 2023 |
| NCT00270257 | Terminated | Phase 3 | Drug Treatment Combined With Drug and Risk Reduction Counseling to Prevent of HIV Infection and Death Among Injection Drug Users | May 2008 | July 2012 |
| NCT00142727 | Terminated | Phase 2 | Opioid Agonist and Antagonist Effects on Opioid Dependence | January 2004 | February 2006 |
| NCT03143543 | Terminated | Phase 1 | Phase I Functional Magnetic Resonance Imaging (fMRI) Pharmacodynamic Studies of Compounds for Opioid Use Disorder and Cocaine Use Disorder | July 2015 | December 6, 2019 |
| NCT02698098 | Terminated | Comparative Evaluation of PUSPENs and C&Cs | August 2012 | September 2015 | |
| NCT03948464 | Terminated | Phase 3 | Slow-Release Oral Morphine for the Treatment of Opioid Use Disorder | December 6, 2019 | June 1, 2020 |
| NCT02741076 | Terminated | Phase 4 | Discontinuation vs Continuation of Long-term Opioid Therapy in Suboptimal and Optimal Responders With Chronic Pain | September 14, 2016 | April 27, 2018 |
| NCT02902835 | Terminated | N/A | BUPrenorphine Facilitated Access and Supportive Treatment --AIM 3 | September 1, 2016 | June 30, 2018 |
| NCT00134875 | Terminated | N/A | Assessing Abuse Potential of Parenteral Buprenorphine/Naloxone in Non-Dependent Opioid Abusers | December 2000 | December 2017 |
| NCT00000243 | Terminated | N/A | Effects of Buprenorphine/Naloxone in Treating Opioid Dependent Individuals Who Are Maintained on Methadone | September 2002 | January 2004 |
| NCT00726960 | Unknown status | Phase 1 | Ability of Aprepitant to Block Opioid Reward in Non-Dependent Opiate Abusers | January 2008 | June 2010 |
| NCT04961294 | Unknown status | N/A | EA for Protracted Withdrawal of OUD | July 2021 | December 2023 |
| NCT03394911 | Unknown status | Phase 3 | Healthy Adult Male Facial Skin Surface Lipid Pheromone p.o. to Treat Opioid Addiction | December 31, 2020 | November 2021 |
| NCT01874964 | Unknown status | N/A | Trial of Methadone Maintenance Versus Methadone Detox in Jail | June 2010 | May 2014 |
| NCT03610672 | Unknown status | N/A | Mobile Intervention for Young Opioid Users | September 15, 2017 | February 28, 2020 |
| NCT00124358 | Unknown status | Phase 4 | Buprenorphine and Integrated HIV Care Evaluation | August 2005 | December 2008 |
| NCT05387408 | Unknown status | N/A | Improving Health and Employment Outcomes Through Workplace Opioid Policies | May 31, 2022 | February 2023 |
| NCT03845699 | Unknown status | Development of an Algorithm That Predicts Hypoventilation Due to an Opioid Overdose | May 15, 2019 | May 14, 2020 | |
| NCT02733822 | Unknown status | Phase 1 | Buccal Versus Injectable Naloxone: a Phase I Healthy Volunteer Study | June 2016 | June 2017 |
| NCT02866266 | Unknown status | ER/LA Opioid Surveillance for Emergency Department Visits and Hospitalizations for Overdose and Poisoning | |||
| NCT02871232 | Unknown status | Surveillance Monitoring of Opioid Abuse in Poison and Drug Treatment Centers | |||
| NCT02897414 | Unknown status | ER/LA Opioid Analgesics - Surveillance Monitoring of State Medical Examiner Databases | |||
| NCT00000327 | Withdrawn | Phase 2 | Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment I(2) - 2 | June 1997 | August 1997 |
| NCT00000328 | Withdrawn | Phase 2 | Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment III) - 3 | July 1997 | August 1997 |
| NCT03137030 | Withdrawn | Phase 1 | A Comparison of Plasma Concentrations of Hydrocodone and Acetaminophen After Administration of Different Amounts of Tablets of a New and a Marketed Tablet Formulation in Healthy Adults | September 2017 | January 2018 |
| NCT03137017 | Withdrawn | Phase 1 | A Comparison of Plasma Concentrations of Hydrocodone and Acetaminophen After Administration of a New and a Marketed Tablet Formulation Under Fasted and Fed Conditions in Healthy Adults | September 2017 | November 2017 |
| NCT00000193 | Withdrawn | Phase 2 | Neurobiology of Opioid Dependence: 2 - 2 | January 1993 | January 1998 |
| NCT00000331 | Withdrawn | Phase 2 | Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-3 - 6 | December 2002 | December 2002 |
| NCT00000195 | Withdrawn | Phase 2 | Neurobiology of Opioid Dependence: 4 - 4 | January 1993 | January 1998 |
| NCT00000329 | Withdrawn | Phase 2 | Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-1 - 4 | April 1999 | August 1999 |
| NCT03678792 | Withdrawn | Phase 3 | Comparison of Three Opioid Detoxification Treatment Regimens | November 15, 2019 | October 25, 2020 |
| NCT00000196 | Withdrawn | Phase 2 | Neurobiology of Opioid Dependence: 5 - 5 | January 1993 | January 1998 |
| NCT00000192 | Withdrawn | Phase 2 | Neurobiology of Opioid Dependence: 1 - 1 | January 1993 | January 1998 |
| NCT03287180 | Withdrawn | N/A | Adolescent Community Reinforcement Approach in Combination With Buprenorphine/Naloxone for Severe Opioid Use | January 1, 2019 | June 9, 2020 |
| NCT04740099 | Withdrawn | N/A | Surviving Opioid Overdose With Naloxone Education and Resuscitation Trial (SOONER) | December 2021 | March 2023 |
| NCT00000194 | Withdrawn | Phase 2 | Neurobiology of Opioid Dependence: 3 - 3 | January 1993 | January 1998 |
| NCT00000326 | Withdrawn | Phase 2 | Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment 1 - 1 | April 1997 | August 1997 |
| NCT00000330 | Withdrawn | Phase 2 | Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-2 - 5 | October 1999 | November 1999 |
- MeSH unique ID (MeSH (Medical Subject Headings))
- D009293