Chronic cough

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Information
Disease name
Chronic cough
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04193176 Completed Phase 3 Efficacy and Safety of Gefapixant (MK-7264) in Women With Chronic Cough and Stress Urinary Incontinence (MK-7264-042) May 10, 2020 September 2, 2022
NCT04525885 Completed Phase 3 A Study of Gefapixant (MK-7264) in Adult Participants With Chronic Cough (MK-7264-030)-China Extension May 17, 2019 September 15, 2022
NCT01297790 Completed Cough Responses to Tussive Agents in Health and Disease November 2009 May 2011
NCT00858624 Completed N/A Neurophysiology and Pharmacology of Cough Reflex Hypersensitivity February 2008 July 2009
NCT01432730 Completed Phase 2 A Study to Assess the Efficacy of Gefapixant (MK-7264/AF-219), in Participants With Chronic Cough (MK-7264-006) September 22, 2011 February 21, 2013
NCT01566968 Completed Novel Endpoints in Cough Challenge Testing January 2011 April 2012
NCT01777867 Completed Cough Reflex Sensitivity and Bronchial Hyper-responsiveness December 2012 February 2016
NCT04193202 Completed Phase 3 Efficacy and Safety of Gefapixant (MK-7264) in Adult Participants With Recent Onset Chronic Cough (MK-7264-043) May 21, 2020 November 3, 2021
NCT05642559 Completed Study for the Development and Validation of Chronic Cough Patient Perspective Questionnaire December 1, 2022 August 31, 2023
NCT01865422 Completed N/A French Linguistic and Metric Validations of Parent-proxy QOL Chronic Cough Specific Questionnaire (PC-QOL) May 2013 June 2014
NCT05392192 Completed Phase 2 A Clinical Trial to Evaluate the Safety and Efficacy in Subjects With Chronic Cough April 7, 2022 April 13, 2023
NCT03172130 Completed N/A Sham CPAP vs. Straight CPAP for Chronic Cough October 13, 2014 November 25, 2019
NCT03449134 Completed Phase 3 A Study of Gefapixant (MK-7264) in Adult Participants With Chronic Cough (MK-7264-027) March 14, 2018 August 17, 2020
NCT03449147 Completed Phase 3 A Study of Gefapixant (MK-7264) in Adult Participants With Chronic Cough (MK-7264-030) March 15, 2018 October 30, 2020
NCT03482713 Completed Phase 2 Study of Gefapixant (MK-7264) in Adult Japanese Participants With Unexplained or Refractory Chronic Cough (MK-7264-033) March 16, 2018 June 7, 2018
NCT03622216 Completed Phase 2 A Dose Escalation Study of Bradanicline in Refractory Chronic Cough November 5, 2018 May 22, 2019
NCT05274516 Completed Phase 1 A Trial of HRS-2261 in Healthy Subjects After Single and Multiple Oral Administration March 28, 2022 October 25, 2022
NCT03639727 Completed N/A Cough in Eastern and Central Finland September 1, 2018 January 31, 2019
NCT03696108 Completed Phase 3 A Study of Gefapixant (MK-7264) in Japanese Adult Participants With Refractory or Unexplained Chronic Cough (MK-7264-038) October 31, 2018 October 7, 2020
NCT01252225 Completed Phase 4 Lidocaine: Effect of Lidocaine in Chronic Cough February 2011 May 2011
NCT04861155 Completed N/A Validation and Evaluation of a Novel Cough Detection Device April 22, 2021 October 26, 2021
NCT04110054 Completed Phase 2 Evaluation of S-600918 in Adults With Refractory Chronic Cough February 13, 2020 December 28, 2020
NCT05689307 Enrolling by invitation N/A Validation Study With a Non-CE Marked Medical Device (MD) March 2, 2023 August 2024
NCT06378671 Recruiting N/A Single-center Clinical Study on the Safety and Effect of Bronchoscopic Cryotherapy in Patients With Chronic Cough April 2024 September 2024
NCT03787511 Recruiting N/A Chronic Cough and Small Fiber Neuropathy March 5, 2019 August 2023
NCT04765722 Recruiting Phase 4 Mepolizumab for the Treatment of Chronic Cough With Eosinophilic Airways Diseases December 14, 2021 April 30, 2024
NCT04866563 Recruiting Phase 2 A Study of Efficacy and Safety of AX-8 in Chronic Cough August 11, 2021 July 2024
NCT04984304 Recruiting N/A Individualized Diagnosis and Treatment of Extraesophageal Reflux in Patients With Chronic Cough June 1, 2021 May 2024
NCT05362097 Recruiting Analysis of the Reliability and Validity of the Chinese Version of CC-QoL March 5, 2023 May 5, 2026
NCT05522699 Recruiting N/A Cough Suppressive Therapy in Patients With Chronic Cough November 3, 2022 December 31, 2024
NCT05813223 Recruiting Early Phase 1 Effect of Gefapixant on Cough-related Brain Activity in Patients With Chronic Cough January 1, 2024 June 30, 2026
NCT06286163 Recruiting Neuroinflammatory Interactions of ATP and P2X3 Receptor in the Airways of Chronic Cough Patients October 1, 2023 June 30, 2025
NCT06376448 Recruiting An Observational Study Using Novel Questionnaire to Characterize Cough Phenotypes in Patients With Chronic Cough October 24, 2022 February 10, 2025
NCT04758351 Recruiting Prospective Study on the Evaluation, Patient Reported Outcomes and Effectiveness of Treatment for Chronic Cough December 14, 2021 April 30, 2024
NCT04654481 Terminated N/A Study of AffloVest in At-Risk Respiratory Patients During COVID-19 Pandemic July 20, 2021 October 19, 2021
NCT03864328 Terminated Phase 2 A Phase 2b Study of Inhaled RVT-1601 for the Treatment of Persistent Cough in IPF March 29, 2019 June 5, 2020
NCT01807832 Unknown status N/A The Use of Capsaicin Challenge for Diagnosis, Monitoring and Follow-up of Chronic Cough. March 2013 December 2013
NCT02196493 Unknown status Phase 3 An Open Label Trial of Azithromycin in Chronic Productive Cough December 2013 December 2016
NCT03638063 Unknown status ATP and Capsaicin Cough Provocation Test in Chronic Cough and Bronchiectasis October 29, 2018 July 2020
NCT01413698 Unknown status Cough Count Validation September 2011 September 2012
NCT01858584 Unknown status N/A Prospective, Comparative, Randomized, Controlled Trial on the Efficacy of the Treatment of Gastroesophageal Reflux Infant With Magnesium Alginate February 2013
NCT04694963 Unknown status A Multi-center Study to Determine the Prevalence and Influence of Pertussis on Subacute Cough in Shenzhen January 1, 2021 December 31, 2021