Primary hypercholesterolemia
Information
- Disease name
- Primary hypercholesterolemia
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05118230 | Active, not recruiting | Study to Assess the Real World Effectiveness of Inclisiran in Chinese Adult Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia | December 9, 2021 | September 30, 2024 | |
| NCT00269217 | Completed | Phase 3 | Lipid Efficacy Study (0524B-022)(COMPLETED) | January 2006 | January 2007 |
| NCT00479388 | Completed | Phase 3 | Study of Extended Release Niacin/Laropiprant on Lipids (0524A-067) | July 2007 | October 2008 |
| NCT00479882 | Completed | Phase 3 | MK-0524B Lipid Study (MK-0524B-063) | June 15, 2007 | June 16, 2008 |
| NCT00704535 | Completed | Evaluation of the Safety, Tolerability and Efficacy of Ezetimibe on a Select Population of Filipinos With Hypercholesterolemia (Study P04748)(COMPLETED) | March 2006 | April 2008 | |
| NCT00724477 | Completed | Retrospective Evaluation of the Percentage of Subjects Who Have Reached Their LDL-C Objectives After Treatment With INEGY (Study P05103)(COMPLETED) | October 2007 | August 2008 | |
| NCT00746811 | Completed | Phase 4 | Effects of Prescription Omega-3 on LDL-C in Primary Hypercholesterolemia | January 2010 | October 2010 |
| NCT00776321 | Completed | Phase 2 | Eprotirome for the Treatment of Dyslipidemia, Efficacy and Safety 12-Week, Phase ii Study to Assess the Safety and Efficacy of KB2115 in Patients With Primary Hypercholesterolemia | September 2006 | October 2007 |
| NCT00867165 | Completed | Phase 3 | Pediatric Study to Evaluate the Efficacy and Safety of Ezetimibe Monotherapy in Children With Primary Hypercholesterolemia (P05522) | May 21, 2009 | April 13, 2012 |
| NCT00871351 | Completed | Phase 4 | Evaluation of Ezetimibe and Atorvastatin Coadministration Versus Atorvastatin or Rosuvastatin Monotherapy in Japanese Patients With Hypercholesterolemia (Study P06027)(COMPLETED) | February 1, 2009 | May 1, 2010 |
| NCT00941603 | Completed | Phase 2 | Phase 2 Dose-Ranging Efficacy and Safety Trial of SCH 900271 in Participants With Primary Hypercholesterolemia or Mixed Hyperlipidemia (P05675) | June 29, 2009 | February 22, 2010 |
| NCT01012219 | Completed | Phase 1 | A Study to Evaluate the Effects of Laropiprant on the Antiplatelet Effects of Clopidogrel and Aspirin in Combination (MK-0524A-114)(COMPLETED) | November 2009 | April 2010 |
| NCT06448962 | Completed | Phase 3 | Phase 3 Study to Evaluate the Efficacy and Safety of Co-administrated AD-2021 and AD-2022 | October 22, 2020 | November 22, 2021 |
| NCT01879319 | Completed | Phase 3 | Study to Assess in Home Use of Evolocumab (AMG 145) Administration Using Either an Automated Mini-doser or a Prefilled Autoinjector/Pen | July 11, 2013 | |
| NCT02087917 | Completed | Phase 2 | A 4-week, Randomized, Placebo-Controlled, Double-Blind, Efficacy and Safety Study of HS-25 in Adults With Primary Hypercholesterolemia | March 2014 | December 2014 |
| NCT02205606 | Completed | Phase 3 | Efficacy/Safety of HCP1306 Tablet Versus HGP0816 Tablet in Patients With Primary Hypercholesterolemia | June 2014 | April 2015 |
| NCT02445352 | Completed | Phase 3 | Efficacy/Safety of DP-R207 Tablet Versus CRESTOR Tablet in Patients With Primary Hypercholesterolemia | July 2014 | March 2015 |
| NCT02941848 | Completed | Phase 1 | Evaluate the Pharmacokinetics and Safety of HCP1306 and Co-administration of HGP0816, HGP1404 in Healthy Male Volunteers | November 2014 | January 2015 |
| NCT03413462 | Completed | Phase 3 | Efficacy and Safety Study of HS-25 in Chinese Adults With Primary Hypercholesterolemia | April 12, 2016 | September 20, 2018 |
| NCT03516955 | Completed | Efficacy and Safety of a Generic Rosuvastatin in a Real-world Setting | November 2014 | August 2015 | |
| NCT03571087 | Completed | Phase 3 | Efficacy and Safety of Combination of Rosuvastatin and Ezetimibe in Patients With Primary Hypercholesterolemia | September 2014 | September 2015 |
| NCT03882905 | Completed | Phase 3 | A Study of SCH 58235 (Ezetimibe) When Added to Ongoing Therapy With a Statin in Participants With Primary Hypercholesterolemia, Known Coronary Heart Disease, or Multiple Cardiovascular Risk Factors (P02173) | January 31, 2001 | July 27, 2001 |
| NCT04584736 | Completed | Phase 3 | To Evaluate the Efficacy and Safety in Patients With Primary Hypercholesterolemia | June 11, 2019 | October 12, 2020 |
| NCT04643093 | Completed | Phase 3 | Compare the Efficacy and Safety of 1PC111 With Pitavastatin and Ezetimibe in Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia | August 1, 2020 | October 5, 2021 |
| NCT04652349 | Completed | Phase 3 | Efficacy and Safety of HGP1910 and HCP1903 in Patients With Primary Hypercholesterolemia | July 6, 2020 | January 14, 2021 |
| NCT04844125 | Completed | Phase 3 | SHR - 1209 Treatment Efficacy and Safety of the Patients With Hypercholesterolemia Ⅲ Period Clinical Research | April 14, 2021 | August 12, 2022 |
| NCT04849000 | Completed | Phase 3 | Study of SHR-1209 in the Treatment of Hypercholesterolemia and Hyperlipidemia Ⅲ Stage | April 23, 2021 | January 13, 2023 |
| NCT05131997 | Completed | Phase 3 | A Study to Evaluate the Efficacy and Safety of AD-221 and AD-221A | November 16, 2021 | June 8, 2022 |
| NCT06184269 | Completed | Phase 1 | A Study to Evaluate the Pharmacokinetics and the Safety After Administration of "BR1017-1" and Co-administration of "BR1017-1A" and "BR1017-1B" | December 23, 2023 | February 18, 2024 |
| NCT00249249 | Completed | Phase 3 | Study to Compare the Efficacy of Pitavastatin With That of Atorvastatin in Lowering Cholesterol Levels | October 2005 | November 2006 |
| NCT01849497 | Completed | Phase 3 | Study to Assess In-home Use of Evolocumab (AMG 145) Using a Prefilled Syringe or a Prefilled Autoinjector/Pen | April 18, 2013 | |
| NCT06386419 | Not yet recruiting | Phase 4 | A Clinical Study to Evaluate the Safety and Effectiveness of Inclisiran Sodium in Indian Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia | May 15, 2024 | August 30, 2025 |
| NCT05657574 | Recruiting | Phase 3 | A Clinical Trial to Evaluate the Efficacy and Safety of CKD-391 and CKD-331 in Patients With Primary Hypercholesterolemia | November 24, 2022 | June 2023 |
| NCT06314919 | Recruiting | A Study to Evaluate the Efficacy and Safety of Fixed-Dose Combination of Pitavastatin/Ezetimib | March 15, 2024 | March 2026 | |
| NCT05930028 | Recruiting | Phase 3 | A Study to Evaluate the Efficacy and Safety of BR1017A and BR1017B Combination Therapy in Essential Hypertension Patients With Primary Hypercholesterolemia | July 13, 2023 | June 2024 |
| NCT05559606 | Recruiting | An OS to Evaluate the Safety & Efficacy of Fixed Dose Combination Therapy With Atorvastatin and Ezetimibe | September 7, 2022 | July 30, 2024 | |
| NCT05399992 | Recruiting | Study Evaluating Effectiveness and Adherence of Inclisiran Plus Standard of Care (SoC) Lipid-lowering Therapy Compared to SoC in ASCVD | September 12, 2022 | April 1, 2027 | |
| NCT06165250 | Recruiting | Phase 3 | A Study to Evaluate the Efficacy and Safety of Co-administrated BR1018B and BR1018C | April 17, 2024 | April 2025 |
| NCT01274559 | Terminated | Phase 3 | Efficacy and Safety of Extended Release (ER) Niacin/Laropiprant When Added to Ongoing Lipid-Modifying Therapy in Patients With High Cholesterol or Abnormal Lipid Levels (MK-0524A-133) | March 1, 2011 | February 26, 2013 |
| NCT01335997 | Terminated | Phase 3 | Efficacy and Safety of Extended-Release Niacin/ Laropiprant/Simvastatin Tablets in Participants With Hypercholesterolemia or Mixed Dyslipidemia (MK-0524B-143) | May 1, 2011 | January 1, 2012 |
| NCT01294683 | Terminated | Phase 3 | A Study to Evaluate Efficacy and Safety of Extended-Release Niacin + Laropiprant + Simvastatin in Participants With Primary Hypercholesterolemia or Mixed Dyslipidemia (MK-0524B-118) | February 4, 2011 | January 17, 2012 |
| NCT03433755 | Terminated | Phase 3 | Safety and Efficacy of Evolocumab in Addition to Optimal Stable Background Statin Therapy in Chinese Participants With Primary Hypercholesterolemia and Mixed Dyslipidemia | May 9, 2019 | May 9, 2020 |
| NCT03464682 | Unknown status | Phase 3 | Efficacy and Safety of HS-25 or in Combination With Atorvastatin in Chinese Adults With Primary Hypercholesterolemia | February 28, 2015 | May 28, 2019 |
| NCT05206578 | Unknown status | Phase 3 | Study to Evaluate the Efficacy and Safety in Patients With Primary Hypercholesterolemia | December 8, 2020 | September 8, 2022 |
| NCT04659070 | Unknown status | Phase 3 | To Evaluate the Efficacy and Safety of Co-administrated Ezetimibe/Rosuvastatin and Telmisartan in Patients With Essential Hypertension and Primary Hypercholesterolemia | July 15, 2020 | May 19, 2022 |
| NCT02009787 | Unknown status | N/A | Efficacy Study of Vitamin D and Statins to Treat Hypercholesterolemia | December 2013 | January 2015 |
| NCT03952169 | Unknown status | N/A | Effect of Probiotics on Lipid Management | May 12, 2019 | December 2022 |
| NCT05798390 | Withdrawn | Treatment With Bempedoic Acid And/Or Its Fixed-dose Combination With Ezetimibe in Routine Clinical Practice in Patients With Primary Hypercholesterolemia Or Mixed Dyslipidemia | September 1, 2023 | April 1, 2026 |
- MedGen concept unique identifier (MedGen Concept name)
- C0342879
- MedGen unique identifier (MedGen Concept name)
- 575264