Annotation Detail
Information
- Associated Genes
- ABCB1
- Associated Variants
- ABCB1 UNKNOWN
- Source Database
- MMMP
- Description
- Non melanoma specific model (prostate cancer). Patients carrying the 2677GG genotype had a significantly longer time to neuropathy
- MMMP State
- genotype 2677GG
- MMMP Molecule
- ABCB1
- MMMP Molecule Alias
- MDR1, P-gp
- MMMP Relationship
- toxicity decreased for
- MMMP Drug
- Docetaxel
- MMMP Model
- 5
- MMMP Reference
- Sissung TM, Clin Cancer Res 2008, 14:4543-9
- MMMP DNA/mRNA/Protein
- DNA
Drugs
Drug Name | Sensitivity | Supported |
---|---|---|
Docetaxel | toxicity decrease | true |