Annotation Detail
Information
- Associated Genes
- ABCC1
- Associated Variants
- ABCC1 UNKNOWN
- Source Database
- MMMP
- Description
- Non melanoma specific model (ovarian cancer). Phase III RCT of carboplatin + either paclitaxel or docetaxel
- MMMP Model
- 5
- MMMP State
- polymorphism IVS18-30C>G
- MMMP Molecule
- ABCC1
- MMMP Molecule Alias
- MRP1
- MMMP Relationship
- toxicity unchanged for
- MMMP Drug
- Carboplatin + Taxane (Paclitaxel or Docetaxel)
- MMMP Reference
- Marsh S, J Clin Oncol 2007, 25:4528-35
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Carboplatin + Taxane (Paclitaxel or Docetaxel) | toxicity unchanged | true |