Annotation Detail
Information
- Associated Genes
- ABCB1
- Associated Variants
- ABCB1 UNKNOWN
- Source Database
- MMMP
- Description
- Non melanoma specific model (ovarian cancer). Phase III RCT of carboplatin + either paclitaxel or docetaxel
- MMMP State
- polymorphism 1236C>T
- MMMP Molecule
- ABCB1
- MMMP Molecule Alias
- MDR1, P-gp
- MMMP Relationship
- toxicity unchanged for
- MMMP Drug
- Carboplatin + Taxane (Paclitaxel or Docetaxel)
- MMMP Model
- 5
- MMMP Reference
- Marsh S, J Clin Oncol 2007, 25:4528-35
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Carboplatin + Taxane (Paclitaxel or Docetaxel) | toxicity unchanged | true |