Annotation Detail
Information
- Associated Genes
- XRCC1
- Associated Variants
- XRCC1 UNKNOWN
- Source Database
- MMMP
- Description
- Non melanoma specific model (lung cancer). This polymorphism was associated with increased gastrointestinal toxicity
- MMMP State
- polymorphism Arg399Gln
- MMMP Molecule
- XRCC1
- MMMP Relationship
- toxicity increased for
- MMMP Drug
- Cisplatin based regimens
- MMMP Model
- 5
- MMMP Reference
- Wang Z, Lung Cancer 2008, 62:99-104
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Cisplatin based regimens | toxicity increased | true |