Annotation Detail
Information
- Associated Genes
- XRCC1
- Associated Variants
-
XRCC1 rs25489
XRCC1 p.Arg280Pro (p.R280P) ( ENST00000262887.10, ENST00000543982.5 )
XRCC1 p.Arg280His (p.R280H) ( ENST00000262887.10, ENST00000543982.5 ) - Source Database
- MMMP
- Description
- Non melanoma specific model (ovarian cancer)
- MMMP State
- polymorphism rs25489
- MMMP Molecule
- XRCC1
- MMMP Relationship
- toxicity unchanged for
- MMMP Drug
- Cisplatin
- MMMP Drug Alias
- CDDP
- MMMP Model
- 5
- MMMP Reference
- Khrunin AV, Pharmacogenomics J 2010, 10:54-61
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Cisplatin | toxicity unchanged | true |