Annotation Detail

Information
Associated Genes
TP53
Associated Variants
TP53 rs1625895
TP53 c.672+62A>G ( ENST00000576024.2, ENST00000359597.8, ENST00000504290.5, ENST00000413465.6, ENST00000455263.6, ENST00000604348.6, ENST00000269305.9, ENST00000445888.6, ENST00000510385.5, ENST00000420246.6, ENST00000504937.5, ENST00000610292.4, ENST00000610538.4, ENST00000610623.4, ENST00000618944.4, ENST00000619186.4, ENST00000619485.4, ENST00000620739.4, ENST00000622645.4, ENST00000714356.1, ENST00000714357.1, ENST00000714359.1, ENST00000714408.1, ENST00000714409.1 )
TP53 c.672+62A>C ( ENST00000618944.4, ENST00000445888.6, ENST00000455263.6, ENST00000619485.4, ENST00000620739.4, ENST00000504937.5, ENST00000619186.4, ENST00000714408.1, ENST00000576024.2, ENST00000610623.4, ENST00000420246.6, ENST00000622645.4, ENST00000714409.1, ENST00000604348.6, ENST00000359597.8, ENST00000413465.6, ENST00000714356.1, ENST00000714359.1, ENST00000610292.4, ENST00000504290.5, ENST00000269305.9, ENST00000714357.1, ENST00000510385.5, ENST00000610538.4 )
Source Database
MMMP
Description
Non melanoma specific model (ovarian cancer)
MMMP State
polymorphism rs1625895
MMMP Molecule
p53
MMMP Molecule Alias
TP53
MMMP Relationship
toxicity unchanged for
MMMP Drug
Cisplatin
MMMP Drug Alias
CDDP
MMMP Model
5
MMMP Reference
Khrunin AV, Pharmacogenomics J 2010, 10:54-61
MMMP DNA/mRNA/Protein
DNA
Drugs
Drug NameSensitivitySupported
Cisplatintoxicity unchangedtrue