Annotation Detail
Information
- Associated Genes
- XRCC1
- Associated Variants
- XRCC1 UNKNOWN
- Source Database
- MMMP
- Description
- Non melanoma specific model (ovarian cancer). This genotype was associated with increased cisplatin-induced hematologic toxicity
- MMMP State
- genotype 399 Arg/Arg (SNP rs25487)
- MMMP Molecule
- XRCC1
- MMMP Relationship
- toxicity increased for
- MMMP Drug
- Cisplatin
- MMMP Drug Alias
- CDDP
- MMMP Model
- 5
- MMMP Reference
- Khrunin AV, Pharmacogenomics J 2010, 10:54-61
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Cisplatin | toxicity increased | true |