Annotation Detail
Information
- Associated Genes
- TP53
- Associated Variants
- TP53 UNKNOWN
- Source Database
- MMMP
- Description
- Non melanoma specific model (ovarian cancer). This genotype was associated with increased cisplatin-induced hematologic toxicity
- MMMP State
- genotype 72 Pro/Pro (SNP rs1042522)
- MMMP Molecule
- p53
- MMMP Molecule Alias
- TP53
- MMMP Relationship
- toxicity increased for
- MMMP Drug
- Cisplatin
- MMMP Drug Alias
- CDDP
- MMMP Model
- 5
- MMMP Reference
- Khrunin AV, Pharmacogenomics J 2010, 10:54-61
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Cisplatin | toxicity increased | true |