Annotation Detail
Information
- Associated Genes
- MSH2
- Associated Variants
-
MSH2 rs2303428
MSH2 c.2006-6T>C ( ENST00000543555.6, ENST00000233146.7, ENST00000406134.5, ENST00000645506.1, ENST00000713854.1, ENST00000713919.1 )
MSH2 rs2303428 - Source Database
- MMMP
- Description
- The genetic variant rs2303428 (MSH2) might serve as a predictive marker for hematologic side effects
- MMMP State
- polymorphism rs2303428
- MMMP Molecule
- MSH2
- MMMP Relationship
- toxicity increased for
- MMMP Drug
- Temozolomide
- MMMP Drug Alias
- TMZ
- MMMP Model
- 5
- MMMP Reference
- Boeckmann L, Pharmacogenet Genomics 2009, 19:760-9
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Temozolomide | toxicity increased | true |