Annotation Detail
Information
- Associated Genes
- UGT1A1
- Associated Variants
- UGT1A1 UNKNOWN
- Source Database
- MMMP
- Description
- Non melanoma specific model (colon cancer). Irinotecan alone or irinotecan-containing regimens
- MMMP State
- polymorphism *28
- MMMP Molecule
- UGT1A1
- MMMP Relationship
- toxicity unchanged for
- MMMP Drug
- Irinotecan
- MMMP Drug Alias
- CPT-11
- MMMP Model
- 5
- MMMP Reference
- Braun MS, J Clin Oncol 2009, 33:5519-28
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Irinotecan | toxicity unchanged | true |