Annotation Detail
Information
- Associated Genes
- SRC
- Associated Variants
- SRC EXPRESSION
- Source Database
- MMMP
- Description
- Uveal melanoma. SRC levels are higher in primary UM and lower in metastatic UM: SRC inhibition (by PP1 or siRNA) is effective in primary but not metastatic UM cell lines
- MMMP State
- expressed
- MMMP Molecule
- SRC
- MMMP Molecule Alias
- c-Src
- MMMP Relationship
- sensitivity to
- MMMP Drug
- PP1
- MMMP Drug Alias
- SRC inhibitor
- MMMP Model
- 3
- MMMP Reference
- Maat W, Br J Cancer 2009, 101:312-9
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| PP1 | Sensitivity | true |