Annotation Detail
Information
- Associated Genes
- HDAC9
- Associated Variants
- HDAC9 UNKNOWN
- Source Database
- MMMP
- Description
- Plitidepsin (a marine depsipeptide) is a HDAC inhibitor. In this trial plitidepsin yielded 5.7% partial response and 14.3% stable disease rates as second line treatment of metastatic melanoma
- MMMP State
- uncharacterized
- MMMP Molecule
- HDAC
- MMMP Molecule Alias
- Histone deacetylase
- MMMP Relationship
- no relationship with
- MMMP Drug
- Plitidepsin
- MMMP Drug Alias
- Aplidin
- MMMP Model
- 5
- MMMP Reference
- Eisen T, Melanoma Res 2009, 19:185-92
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Plitidepsin | Resitance or Non-Reponse | true |