Annotation Detail
Information
- Associated Genes
- FGF2
- Associated Variants
- FGF2 EXPRESSION
- Source Database
- MMMP
- Description
- Uveal melanoma. Proliferation was strongly reduced by the antisense oligonucleotide-mediated depletion of endogenous FGF2, immunoneutralization of secreted FGF2, and pharmacologic inhibition of FGFR1
- MMMP State
- expressed
- MMMP Molecule
- FGF-2
- MMMP Molecule Alias
- Fibroblast growth factor 2 (bFGF)
- MMMP Relationship
- sensitivity to
- MMMP Drug
- FGF2 antibody (antagonist)
- MMMP Model
- 3
- MMMP Reference
- Lefevre G, Invest Ophthalmol Vis Sci 2009, 50:1047-57
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| FGF2 antibody (antagonist) | Sensitivity | true |