Annotation Detail
Information
- Associated Genes
- KDR
- Associated Variants
- KDR EXPRESSION
- Source Database
- MMMP
- Description
- Sorafenib is a BRAF CRAF VEGFR and PDGFR inhibitor. VEGFR2 expression was significantly higher in pretreatment specimens from patients with a complete or partial response to this regimen (metastatic setting)
- MMMP State
- expressed
- MMMP Molecule
- VEGFR2
- MMMP Molecule Alias
- VEGF receptor 2
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Sorafenib + Carboplatin + Paclitaxel
- MMMP Model
- 5
- MMMP Reference
- Jilaveanu L, Clin Cancer Res 2009, 15:1076-85
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Sorafenib + Carboplatin + Paclitaxel | Sensitivity | true |