Annotation Detail
Information
- Associated Genes
- ROS1
- Associated Variants
- ROS1 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- Elesclomol is a small molecule inducing oxidative stress by increasing ROS levels
- MMMP State
- downregulated by
- MMMP Molecule
- ROS
- MMMP Molecule Alias
- Reactive oxygen species
- MMMP Modifier
- N-acetylcysteine
- MMMP Modifier Alias
- NAC
- MMMP Relationship
- resistance to
- MMMP Drug
- Elesclomol
- MMMP Model
- 3
- MMMP Reference
- Kirshner JR, Mol Cancer Ther 2008, 7:2319-27
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Elesclomol | Resitance or Non-Reponse | true |