Annotation Detail

Information
Associated Genes
APAF1
Associated Variants
APAF1 EXPRESSION
Source Database
MMMP
Description
Using melanoma cells expressing or not expressing APAF1, investigators found that response to high dose etoposide is better in APAF1 positive cells
MMMP State
expressed
MMMP Molecule
APAF1
MMMP Relationship
sensitivity to
MMMP Drug
Etoposide
MMMP Drug Alias
VP-16
MMMP Model
3
MMMP Reference
Zanon M, Cancer Res 2004, 64:7386-94
Drugs
Drug NameSensitivitySupported
EtoposideSensitivitytrue