Annotation Detail

Information
Associated Genes
APAF1
Associated Variants
APAF1 EXPRESSION
Source Database
MMMP
Description
Results in melanoma cells expressing or not expressing APAF-1 suggest that the response of human melanoma cells to different proapoptotic agents may be independent of their APAF1 expression levels
MMMP State
expressed
MMMP Molecule
APAF1
MMMP Relationship
no relationship with
MMMP Drug
Cisplatin
MMMP Drug Alias
CDDP
MMMP Model
3
MMMP Reference
Zanon M, Cancer Res 2004, 64:7386-94
Drugs
Drug NameSensitivitySupported
CisplatinResitance or Non-Reponsetrue