Annotation Detail
Information
- Associated Genes
- AKT1
- Associated Variants
- AKT1 OVEREXPRESSION
- Source Database
- MMMP
- Description
- LY294002: PI3K inhibitor. Overexpression of AKT protects WM9 melanoma cells from apoptosis induced by LY294002 or AG1478
- MMMP State
- upregulated by
- MMMP Molecule
- AKT
- MMMP Molecule Alias
- PKB
- MMMP Modifier
- AKT genetic engineering
- MMMP Relationship
- resistance to
- MMMP Drug
- LY294002
- MMMP Drug Alias
- AKT inhibitor
- MMMP Model
- 3
- MMMP Reference
- Ivanov VN, Oncogene 2005, 24:616-26
- MMMP DNA/mRNA/Protein
- mRNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| LY294002 | Resitance or Non-Reponse | true |