Annotation Detail

Information
Associated Genes
MAP2K7
Associated Variants
MAP2K7 EXPRESSION
Source Database
MMMP
Description
PD0325901 exerts potent growth-inhibitory, proapoptotic, and antiangiogenic activity in melanoma (regardless of BRAF mutation status)
MMMP State
expressed
MMMP Molecule
MEK
MMMP Relationship
sensitivity to
MMMP Drug
PD0325901
MMMP Model
4
MMMP Reference
Ciuffreda L, Neoplasia 2009, 11:720-31
Drugs
Drug NameSensitivitySupported
PD0325901Sensitivitytrue