Annotation Detail
Information
- Associated Genes
- BRAF
- Associated Variants
- BRAF WILD_TYPE
- Source Database
- MMMP
- Description
- PD0325901 is a MEK inhibitor with significant anti-melanoma activity independently of BRAF mutational status
- MMMP State
- wild type (vs mutated)
- MMMP Molecule
- BRAF
- MMMP Molecule Alias
- B-Raf
- MMMP Relationship
- no relationship with
- MMMP Drug
- PD0325901
- MMMP Model
- 4
- MMMP Reference
- Ciuffreda L, Neoplasia 2009, 11:720-31
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| PD0325901 | Resitance or Non-Reponse | true |