Annotation Detail
Information
- Associated Genes
- ING1
- Associated Variants
- ING1 EXPRESSION
- Source Database
- MMMP
- Description
- The tumor suppressor p33ING1 (shares many biological functions with p53, such as cell cycle arrest, DNA repair, apoptosis, and chemosensitivity) does not affect camptothecin-induced cell death in melanoma cells (cell survival assay and flow cytometry analysis showed no significant difference among cells transfected with vector, p33ING1, and antisense p33ING1)
- MMMP State
- expressed
- MMMP Molecule
- p33ING1
- MMMP Relationship
- no relationship with
- MMMP Drug
- Camptothecin
- MMMP Model
- 3
- MMMP Reference
- Cheung KJ, Int J Oncol 2002, 20:1319-22
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Camptothecin | Resitance or Non-Reponse | true |