Annotation Detail
Information
- Associated Genes
- SNAI2
- Associated Variants
- SNAI2 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- Short interfering RNA directed against the SLUG gene increases cell death induction in human melanoma cell lines exposed to cisplatin and fotemustine. Slug inhibition seems to act through PUMA upregulation
- MMMP State
- downregulated by
- MMMP Molecule
- SLUG
- MMMP Molecule Alias
- Snail
- MMMP Modifier
- Slug siRNA
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Fotemustine
- MMMP Model
- 3
- MMMP Reference
- Vannini I, Cell Oncol 2007, 29:279-87
- MMMP DNA/mRNA/Protein
- mRNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Fotemustine | Sensitivity | true |