Annotation Detail
Information
- Associated Genes
- SOCS3
- Associated Variants
- SOCS3 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- SOCS3 inhibition seems to act through STAT1 activation by phosphorylation
- MMMP State
- downregulated by
- MMMP Molecule
- SOCS3
- MMMP Molecule Alias
- Suppressor of cytokine signaling 3
- MMMP Modifier
- SOCS3 siRNA
- MMMP Relationship
- sensitivity to
- MMMP Drug
- IL-6
- MMMP Drug Alias
- Interleukin-6
- MMMP Model
- 3
- MMMP Reference
- Komyod W, Mol Cancer Res 2007, 5:271-81
- MMMP DNA/mRNA/Protein
- mRNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| IL-6 | Sensitivity | true |