Annotation Detail
Information
- Associated Genes
- IGF1R
- Associated Variants
- IGF1R UNDEREXPRESSION
- Source Database
- MMMP
- Description
- These results support development of IGF1R targeting as therapy for melanoma, regardless of the presence of activating mutations in the RAS-RAF pathway
- MMMP State
- downregulated by
- MMMP Molecule
- IGF1R
- MMMP Molecule Alias
- IGF1 receptor
- MMMP Modifier
- IGF1R siRNA
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Cisplatin
- MMMP Drug Alias
- CDDP
- MMMP Model
- 3
- MMMP Reference
- Yeh AH, Oncogene 2006, 25:6574-81
- MMMP DNA/mRNA/Protein
- mRNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Cisplatin | Sensitivity | true |