Annotation Detail
Information
- Associated Genes
- HDAC1
- Associated Variants
- HDAC1 OVEREXPRESSION
- Source Database
- MMMP
- Description
- Butyrate: HDAC inhibitor. Overexpression of histone deacetylase 1 confers resistance to sodium butyrate-mediated apoptosis in melanoma cells through a p53-mediated pathway
- MMMP State
- upregulated by
- MMMP Molecule
- HDAC1
- MMMP Molecule Alias
- Histone deacetylase 1
- MMMP Modifier
- HDAC1 genetic engineering
- MMMP Relationship
- resistance to
- MMMP Drug
- Butyric acid
- MMMP Drug Alias
- HDAC inhibitor
- MMMP Model
- 3
- MMMP Reference
- Bandyopadhyay D, Cancer Res 2004, 64:7706-10
- MMMP DNA/mRNA/Protein
- mRNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Butyric acid | Resitance or Non-Reponse | true |