Annotation Detail

Information
Associated Genes
CTLA4
Associated Variants
CTLA4 UNKNOWN
Source Database
MMMP
Description
Phase III RCT of tremelimumab versus physician choice (dacarbazine or temozolomide)
MMMP Drug
Tremelimumab
MMMP State
uncharacterized
MMMP Molecule
CTLA4
MMMP Relationship
no relationship with
MMMP Drug Alias
CTLA4 antibody (antagonist) CP-675,206
MMMP Model
6
MMMP Reference
Ribas A, J Clin Oncol 2008, 26: May 20 suppl, Abstract LBA9011
Drugs
Drug NameSensitivitySupported
TremelimumabResitance or Non-Reponsetrue