Annotation Detail
Information
- Associated Genes
- CTLA4
- Associated Variants
- NC_000002.12:g.203867624C>T ( ENST00000696479.1 )
- Source Database
- MMMP
- Description
- Influence of cytotoxic T lymphocyte-associated antigen 4 (CTLA4) common polymorphisms on outcome in treatment of melanoma patients with CTLA-4 blockade
- MMMP State
- polymorphism rs5742909
- MMMP Molecule
- CTLA4
- MMMP Relationship
- no relationship with
- MMMP Drug
- Ipilimumab
- MMMP Drug Alias
- CTLA4 antibody (antagonist)
- MMMP Model
- 5
- MMMP Reference
- Breunis WB, J Immunother 2008, 31:586-90
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Ipilimumab | Resitance or Non-Reponse | true |