Annotation Detail

Information
Associated Genes
ATF2
Associated Variants
ATF2 UNDEREXPRESSION
Source Database
MMMP
Description
Cells were transfected with ATF2 cDNA lacking the transactivation domain (ATF2(delta1-195)): these cells showed weaker transcriptional activities and an altered pattern of homo/hetero dimers (similar article by the same investigators: Bhoumik A, Clin Cancer Res 2001, 7:331-42)
MMMP State
downregulated by
MMMP Molecule
ATF2
MMMP Modifier
ATF2 dominant negative
MMMP Relationship
sensitivity to
MMMP Drug
Cytarabine
MMMP Drug Alias
Cytosine arabinoside
MMMP Model
3
MMMP Reference
Ronai Z, Oncogene 1998, 16:523-31
Drugs
Drug NameSensitivitySupported
CytarabineSensitivitytrue