Annotation Detail
Information
- Associated Genes
- CREB1
- Associated Variants
- CREB1 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- Through its transcriptional activity, CREB plays an important role in the acquisition of characteristic phenotypes of human melanoma cells including resistance to irradiation
- MMMP State
- downregulated by
- MMMP Molecule
- CREB
- MMMP Molecule Alias
- cAMP response element binding protein
- MMMP Modifier
- CREB dominant negative
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Radiotherapy
- MMMP Model
- 3
- MMMP Reference
- Yang YM, Oncogene 1996, 12:2223-33
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Radiotherapy | Sensitivity | true |