Annotation Detail
Information
- Associated Genes
- BRAF
- Associated Variants
- BRAF V600E
- Source Database
- MMMP
- Description
- Isolated limb infusion model. p16INK4a expression and absence of activated B-RAF are independent predictors of chemosensitivity in melanoma tumors
- MMMP State
- mut V600E
- MMMP Molecule
- BRAF
- MMMP Molecule Alias
- B-Raf
- MMMP Relationship
- resistance to
- MMMP Drug
- Melphalan + actinomycin-D
- MMMP Model
- 5
- MMMP Reference
- Gallagher SJ, Neoplasia 2008, 10:1231-9
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Melphalan + actinomycin-D | Resitance or Non-Reponse | true |