Annotation Detail

Information
Associated Genes
BRAF
Associated Variants
BRAF G469E
Source Database
MMMP
Description
Sorafenib: BRAF, CRAF, VEGFR and PDGFR inhibitor
MMMP State
mut G469E
MMMP Molecule
BRAF
MMMP Molecule Alias
B-Raf
MMMP Relationship
sensitivity to
MMMP Drug
Sorafenib
MMMP Drug Alias
Nexavar (R)
MMMP Model
3
MMMP Reference
Smalley KS, Oncogene 2009, 28:85-94
MMMP DNA/mRNA/Protein
DNA
Drugs
Drug NameSensitivitySupported
SorafenibSensitivitytrue