Annotation Detail
Information
- Associated Genes
- CDKN2A
- Associated Variants
- CDKN2A EXPRESSION
- Source Database
- MMMP
- Description
- Melanoma cells lacking p16 are more sensitive than those expressing p16. Flavopiridol inhibits CDK and seems to act as p16 in p16 negative cells
- MMMP State
- expressed
- MMMP Molecule
- CDKN2A
- MMMP Molecule Alias
- p16, INK4A
- MMMP Relationship
- resistance to
- MMMP Drug
- Flavopiridol
- MMMP Model
- 3
- MMMP Reference
- Robinson WA, Melanoma Res 2003, 13:231-8
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Flavopiridol | Resitance or Non-Reponse | true |