Annotation Detail
Information
- Associated Genes
- BRAF
- Associated Variants
- BRAF V600E
- Source Database
- MMMP
- Description
- When present, BRAF(V599E) appears to be essential for melanoma cell viability and transformation and, therefore, represents an attractive therapeutic target in the majority of melanomas that harbor the mutation
- MMMP State
- mut V600E
- MMMP Molecule
- BRAF
- MMMP Molecule Alias
- B-Raf
- MMMP Relationship
- sensitivity to
- MMMP Drug
- BRAF siRNA
- MMMP Model
- 3
- MMMP Reference
- Hingorani SR, Cancer Res 2003, 63:5198-202
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| BRAF siRNA | Sensitivity | true |