Annotation Detail
Information
- Associated Genes
- BRAF
- Associated Variants
- BRAF V600E
- Source Database
- MMMP
- Description
- No objective responses were observed, either in BRAF mutant or wild type tumors
- MMMP State
- mut V600E
- MMMP Molecule
- BRAF
- MMMP Molecule Alias
- B-Raf
- MMMP Relationship
- no relationship with
- MMMP Drug
- 17-AAG
- MMMP Drug Alias
- Tanespimycin (17-allylamino-17-demethoxygeldanamycin)
- MMMP Model
- 5
- MMMP Reference
- Solit DB, Clin Cancer Res 2008, 14:8302-7
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| 17-AAG | Resitance or Non-Reponse | true |