Annotation Detail
Information
- Associated Genes
- BRAF
- Associated Variants
- BRAF V600E
- Source Database
- MMMP
- Description
- PLX 4720 is a BRAF inhibitor with high selectivity for mutated BRAF V600E (compared to wild type)
- MMMP State
- mut V600E
- MMMP Molecule
- BRAF
- MMMP Molecule Alias
- B-Raf
- MMMP Relationship
- sensitivity to
- MMMP Drug
- PLX 4720
- MMMP Model
- 4
- MMMP Reference
- Tsai J, Proc Natl Acad Sci USA 2008, 105:3041-6
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| PLX 4720 | Sensitivity | true |